it is produced from the cleavage of pre-pro-opiomelanocortin by various endopeptidases, along with other physiologically active peptide fragments such as β-lipotropin, γ-lipotropin, melanocyte stimulating hormone (msh) and β-endorphin. it is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Corticotropin Activation of Cortisol Production'