HMDB0000073 (Dopamine) HMDB0000216 (Norepinephrine) HMDB0000217 (NADP) HMDB0000221 (NADPH) HMDB0000259 (Serotonin) HMDB0000464 (Calcium) HMDB0000538 (Adenosine triphosphate) HMDB0000586 (Potassium) HMDB0000588 (Sodium) HMDB0001341 (ADP)
- HMDB0000588 (Sodium)
- Desipramine Action Pathway
- it does so by competing for the same binding site as norepinephrine on the sodium-dependent noradraneline transporter (slc6a2) and by competing with serotonin for binding to the sodium-dependent serotonin transporter (slc6a4). this increases the concentrations of both norepinephrine and serotonin in their respective synapses and reverses the state of low concentrations of both neurotransmitters found in depression.
- Parent Term
- Biochemical pathway
- Parent Definition
- A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
- Other Metabolites Mapped to 'Desipramine Action Pathway'