Ontological Term Details

Metabolite
HMDB0000254 (Succinic acid)
Term
Ketone Body Metabolism
Definition
the first two are synthesized from acetyl-coa, in the mitochondria of liver cells; acetone is formed by spontaneous decarboxylation of acetoacetate. ketone body synthesis (ketogenesis) in liver is effectively irreversible because the enzyme that catalyzes the conversion of acetoacetate to acetoacetyl-coa is not present in liver cells.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Ketone Body Metabolism'
  • HMDB0000011 ((R)-3-Hydroxybutyric acid)
  • HMDB0000060 (Acetoacetic acid)
  • HMDB0000254 (Succinic acid)
  • HMDB0000902 (NAD)
  • HMDB0001022 (Succinyl-CoA)
  • HMDB0001206 (Acetyl-CoA)
  • HMDB0001375 (3-Hydroxy-3-methylglutaryl-CoA)
  • HMDB0001423 (Coenzyme A)
  • HMDB0001484 (Acetoacetyl-CoA)
  • HMDB0001487 (NADH)
  • References