opiate receptors are coupled with g-protein receptors and function as both positive and negative regulators of synaptic transmission via g-proteins that activate effector proteins. as the effector system is adenylate cyclase and camp located at the inner surface of the plasma membrane, opioids decrease intracellular camp by inhibiting adenylate cyclase.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Tramadol Action Action Pathway'