Record Information |
---|
Version | 4.0 |
---|
Status | Expected but not Quantified |
---|
Creation Date | 2005-11-16 15:48:42 UTC |
---|
Update Date | 2019-11-08 16:22:08 UTC |
---|
HMDB ID | HMDB0001187 |
---|
Secondary Accession Numbers | |
---|
Metabolite Identification |
---|
Common Name | D-myo-Inositol 1,3,4,6-tetrakisphosphate |
---|
Description | D-myo-Inositol 1,3,4,6-tetrakisphosphate, also known as Ins(1,3,4,6)P4, belongs to the class of organic compounds known as inositol phosphates. Inositol phosphates are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. D-myo-Inositol 1,3,4,6-tetrakisphosphate is an extremely strong acidic compound (based on its pKa). D-myo-Inositol 1,3,4,6-tetrakisphosphate participates in a number of enzymatic reactions. In particular, D-myo-inositol 1,3,4,6-tetrakisphosphate can be converted into D-myo-inositol 1,3,4,5,6-pentakisphosphate through the action of the enzyme inositol polyphosphate multikinase. In addition, D-myo-inositol 1,3,4,6-tetrakisphosphate can be biosynthesized from inositol 1,3,4-trisphosphate; which is mediated by the enzyme inositol-tetrakisphosphate 1-kinase. In humans, D-myo-inositol 1,3,4,6-tetrakisphosphate is involved in inositol phosphate metabolism and is a substrate for the tyrosine-protein kinase BTK. |
---|
Structure | |
---|
Synonyms | Value | Source |
---|
D-Myo-inositol 1,3,4,6-tetrakisphosphate | ChEBI | Inositol 1,3,4,6-tetrakisphosphate | ChEBI | Inositol-1,3,4,6-tetrakisphosphate | ChEBI | Inositol-1,3,4,6-tetraphosphate | ChEBI | Ins-1,3,4,6-P4 | ChEBI | Myo-inositol-1,3,4,6-tetrakisphosphate | ChEBI | D-Myo-inositol 1,3,4,6-tetrakisphosphoric acid | Generator | Inositol 1,3,4,6-tetrakisphosphoric acid | Generator | Inositol-1,3,4,6-tetrakisphosphoric acid | Generator | Inositol-1,3,4,6-tetraphosphoric acid | Generator | Myo-inositol-1,3,4,6-tetrakisphosphoric acid | Generator | 1D-Myo-inositol 1,3,4,6-tetrakisphosphoric acid | Generator | D-Myo-inositol 1,3,4,5-tetrakis-*phosphate potass | HMDB | D-Myo-inositol-1,3,4,5-tetrakisphosphate octapotassium salt | HMDB | 1D-myo-Inositol 1,3,4,6-tetrakisphosphate | HMDB | Inositol 1,3,4,6-tetrakis(phosphate) | HMDB | Inositol 1,3,4,6-tetraphosphate | HMDB | Ins(1,3,4,6)P4 | HMDB | D-myo-Inositol 1,3,4,6-tetraphosphate | HMDB |
|
---|
Chemical Formula | C6H16O18P4 |
---|
Average Molecular Weight | 500.0755 |
---|
Monoisotopic Molecular Weight | 499.928709756 |
---|
IUPAC Name | {[(1R,2s,3S,4S,5r,6R)-2,5-dihydroxy-3,4,6-tris(phosphonooxy)cyclohexyl]oxy}phosphonic acid |
---|
Traditional Name | [(1R,2s,3S,4S,5r,6R)-2,5-dihydroxy-3,4,6-tris(phosphonooxy)cyclohexyl]oxyphosphonic acid |
---|
CAS Registry Number | 110298-84-5 |
---|
SMILES | O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H](O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O |
---|
InChI Identifier | InChI=1S/C6H16O18P4/c7-1-3(21-25(9,10)11)5(23-27(15,16)17)2(8)6(24-28(18,19)20)4(1)22-26(12,13)14/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20)/t1-,2+,3-,4+,5-,6+ |
---|
InChI Key | ZAWIXNGTTZTBKV-JMVOWJSSSA-N |
---|
Chemical Taxonomy |
---|
Description | This compound belongs to the class of organic compounds known as inositol phosphates. These are compounds containing a phosphate group attached to an inositol (or cyclohexanehexol) moiety. |
---|
Kingdom | Organic compounds |
---|
Super Class | Organic oxygen compounds |
---|
Class | Organooxygen compounds |
---|
Sub Class | Alcohols and polyols |
---|
Direct Parent | Inositol phosphates |
---|
Alternative Parents | |
---|
Substituents | - Inositol phosphate
- Monoalkyl phosphate
- Cyclohexanol
- Alkyl phosphate
- Phosphoric acid ester
- Organic phosphoric acid derivative
- Secondary alcohol
- Organic oxide
- Hydrocarbon derivative
- Aliphatic homomonocyclic compound
|
---|
Molecular Framework | Aliphatic homomonocyclic compounds |
---|
External Descriptors | |
---|
Ontology |
---|
|
Disposition | Source: Biological location: |
---|
Process | Naturally occurring process: |
---|
Role | Industrial application: |
---|
Physical Properties |
---|
State | Solid |
---|
Experimental Properties | Property | Value | Reference |
---|
Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
|
---|
Predicted Properties | |
---|