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Showing metabocard for Nitroprusside (HMDB0014470)

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IdentificationTaxonomyOntologyPhysical propertiesSpectraBiological propertiesConcentrationsLinksReferencesenzymes (3) Show 3 proteinsXML
enzymes (3) Show 3 proteins
Record Information
Version5.0
StatusExpected but not Quantified
Creation Date2012-09-06 15:16:49 UTC
Update Date2022-03-07 02:51:38 UTC
HMDB IDHMDB0014470
Secondary Accession Numbers
  • HMDB14470
Metabolite Identification
Common NameNitroprusside
DescriptionNitroprusside is only found in individuals that have used or taken this drug. It serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency. [Wikipedia ]One molecule of sodium nitroprusside is metabolized by combination with hemoglobin to produce one molecule of cyanmethemoglobin and four CN- ions; methemoglobin, obtained from hemoglobin, can sequester cyanide as cyanmethemoglobin; thiosulfate reacts with cyanide to produce thiocyanate; thiocyanate is eliminated in the urine; cyanide not otherwise removed binds to cytochromes. Cyanide ion is normally found in serum; it is derived from dietary substrates and from tobacco smoke. Cyanide binds avidly (but reversibly) to ferric ion (Fe+++), most body stores of which are found in erythrocyte methemoglobin (metHgb) and in mitochondrial cytochromes. When CN is infused or generated within the bloodstream, essentially all of it is bound to methemoglobin until intraerythrocytic methemoglobin has been saturated.Once activated to NO, it activates guanylate cyclase in vascular smooth muscle and increases intracellular production of cGMP. cGMP stimulates calcium movement from the cytoplasm to the endoplasmic reticulum and reduces calcium available to bind with calmodulin. This eventually leads to vascular smooth muscle relaxation and vessel dilatation.
Structure
Data?1582753183
MOL3D MOLSDF3D SDFPDB3D PDBSMILESInChI

MOL for HMDB0014470 (Nitroprusside)


  Mrv0541 02231214362D          

 13 12  0  0  0  0            999 V2000
    0.0000   -1.6500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 Fe  0  6  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  3  3  0  0  0  0
  2  7  1  0  0  0  0
  2  5  3  0  0  0  0
  7  3  1  0  0  0  0
  7  4  1  0  0  0  0
  4  6  3  0  0  0  0
  7 12  1  0  0  0  0
  7  8  1  0  0  0  0
  7 10  1  0  0  0  0
  8  9  3  0  0  0  0
 10 11  3  0  0  0  0
 12 13  2  0  0  0  0
M  CHG  1   7  -2
M  END
Download

3D MOL for HMDB0014470 (Nitroprusside)

HMDB0014470
     RDKit          3D
Nitroprusside
 13 12  0  0  0  0  0  0  0  0999 V2000
   -3.1753    0.2201    1.5323 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3467    0.7779    0.9667 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9400    1.7286   -0.0081 Fe  0  0  0  0  0  6  0  0  0  0  0  0
    0.5090    2.5977   -0.9966 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3535    3.1093   -1.5825 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9777    3.3846    0.0025 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5873    4.3583    0.0090 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0845    2.1915    1.6904 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4106    2.4551    2.6925 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7519    1.1572   -1.6950 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2341    0.8134   -2.6789 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.1089    0.0781   -0.0179 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.0344   -0.6219    0.0857 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  3  0
  2  3  1  0
  3  4  1  0
  4  5  3  0
  3  6  1  0
  6  7  3  0
  3  8  1  0
  8  9  3  0
  3 10  1  0
 10 11  3  0
  3 12  1  0
 12 13  2  0
M  CHG  1   3  -2
M  END
Download

3D SDF for HMDB0014470 (Nitroprusside)


  Mrv0541 02231214362D          

 13 12  0  0  0  0            999 V2000
    0.0000   -1.6500    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.7145    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000   -0.8250    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145    0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289    0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289    0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.0000    0.0000 Fe  0  6  0  0  0  0  0  0  0  0  0  0
    0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.4289   -0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.7145   -0.4125    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.4289   -0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    0.8250    0.0000 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.0000    1.6500    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  3  3  0  0  0  0
  2  7  1  0  0  0  0
  2  5  3  0  0  0  0
  7  3  1  0  0  0  0
  7  4  1  0  0  0  0
  4  6  3  0  0  0  0
  7 12  1  0  0  0  0
  7  8  1  0  0  0  0
  7 10  1  0  0  0  0
  8  9  3  0  0  0  0
 10 11  3  0  0  0  0
 12 13  2  0  0  0  0
M  CHG  1   7  -2
M  END
> <DATABASE_ID>
HMDB0014470

> <DATABASE_NAME>
hmdb

> <SMILES>
O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N

> <INCHI_IDENTIFIER>
InChI=1S/5CN.Fe.NO/c5*1-2;;1-2/q;;;;;2*-1

> <INCHI_KEY>
ASPOIVQEUUCDQT-UHFFFAOYSA-N

> <FORMULA>
C5FeN6O

> <MOLECULAR_WEIGHT>
215.938

> <EXACT_MASS>
215.948300785

> <JCHEM_ACCEPTOR_COUNT>
6

> <JCHEM_AVERAGE_POLARIZABILITY>
16.522119235660675

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
-2

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
pentacyano(nitroso)irondiuide

> <JCHEM_LOGP>
0.07120000000000004

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
0

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-2

> <JCHEM_PKA_STRONGEST_BASIC>
-3.287197304660514

> <JCHEM_POLAR_SURFACE_AREA>
148.38

> <JCHEM_REFRACTIVITY>
39.4351

> <JCHEM_ROTATABLE_BOND_COUNT>
1

> <JCHEM_RULE_OF_FIVE>
1

> <JCHEM_TRADITIONAL_IUPAC>
nitroprusside

> <JCHEM_VEBER_RULE>
0

$$$$
Download

3D-SDF for HMDB0014470 (Nitroprusside)

HMDB0014470
     RDKit          3D
Nitroprusside
 13 12  0  0  0  0  0  0  0  0999 V2000
   -3.1753    0.2201    1.5323 N   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3467    0.7779    0.9667 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.9400    1.7286   -0.0081 Fe  0  0  0  0  0  6  0  0  0  0  0  0
    0.5090    2.5977   -0.9966 C   0  0  0  0  0  0  0  0  0  0  0  0
    1.3535    3.1093   -1.5825 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9777    3.3846    0.0025 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5873    4.3583    0.0090 N   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0845    2.1915    1.6904 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.4106    2.4551    2.6925 N   0  0  0  0  0  0  0  0  0  0  0  0
   -1.7519    1.1572   -1.6950 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2341    0.8134   -2.6789 N   0  0  0  0  0  0  0  0  0  0  0  0
    0.1089    0.0781   -0.0179 N   0  0  0  0  0  0  0  0  0  0  0  0
    1.0344   -0.6219    0.0857 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  3  0
  2  3  1  0
  3  4  1  0
  4  5  3  0
  3  6  1  0
  6  7  3  0
  3  8  1  0
  8  9  3  0
  3 10  1  0
 10 11  3  0
  3 12  1  0
 12 13  2  0
M  CHG  1   3  -2
M  END
Download

PDB for HMDB0014470 (Nitroprusside)

HEADER    PROTEIN                                 23-FEB-12   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   23-FEB-12         0                                  
HETATM    1  N   UNK     0       0.000  -3.080   0.000  0.00  0.00           N+0
HETATM    2  C   UNK     0       1.334   0.770   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0       0.000  -1.540   0.000  0.00  0.00           C+0
HETATM    4  C   UNK     0      -1.334   0.770   0.000  0.00  0.00           C+0
HETATM    5  N   UNK     0       2.667   1.540   0.000  0.00  0.00           N+0
HETATM    6  N   UNK     0      -2.667   1.540   0.000  0.00  0.00           N+0
HETATM    7 Fe   UNK     0       0.000   0.000   0.000  0.00  0.00          Fe-2
HETATM    8  C   UNK     0       1.334  -0.770   0.000  0.00  0.00           C+0
HETATM    9  N   UNK     0       2.667  -1.540   0.000  0.00  0.00           N+0
HETATM   10  C   UNK     0      -1.334  -0.770   0.000  0.00  0.00           C+0
HETATM   11  N   UNK     0      -2.667  -1.540   0.000  0.00  0.00           N+0
HETATM   12  N   UNK     0       0.000   1.540   0.000  0.00  0.00           N+0
HETATM   13  O   UNK     0       0.000   3.080   0.000  0.00  0.00           O+0
CONECT    1    3                                                            
CONECT    2    7    5                                                       
CONECT    3    1    7                                                       
CONECT    4    7    6                                                       
CONECT    5    2                                                            
CONECT    6    4                                                            
CONECT    7    2    3    4   12                                             
CONECT    7    8   10                                   
CONECT    8    7    9                                                       
CONECT    9    8                                                            
CONECT   10    7   11                                                       
CONECT   11   10                                                            
CONECT   12    7   13                                                       
CONECT   13   12                                                            
MASTER        0    0    0    0    0    0    0    0   13    0   24    0
END
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3D PDB for HMDB0014470 (Nitroprusside)

COMPND    HMDB0014470
HETATM    1  N1  UNL     1      -3.175   0.220   1.532  1.00  0.00           N  
HETATM    2  C1  UNL     1      -2.347   0.778   0.967  1.00  0.00           C  
HETATM    3 FE1  UNL     1      -0.940   1.729  -0.008  1.00  0.00          FE2-
HETATM    4  C2  UNL     1       0.509   2.598  -0.997  1.00  0.00           C  
HETATM    5  N2  UNL     1       1.353   3.109  -1.583  1.00  0.00           N  
HETATM    6  C3  UNL     1      -1.978   3.385   0.003  1.00  0.00           C  
HETATM    7  N3  UNL     1      -2.587   4.358   0.009  1.00  0.00           N  
HETATM    8  C4  UNL     1      -0.085   2.192   1.690  1.00  0.00           C  
HETATM    9  N4  UNL     1       0.411   2.455   2.692  1.00  0.00           N  
HETATM   10  C5  UNL     1      -1.752   1.157  -1.695  1.00  0.00           C  
HETATM   11  N5  UNL     1      -2.234   0.813  -2.679  1.00  0.00           N  
HETATM   12  N6  UNL     1       0.109   0.078  -0.018  1.00  0.00           N  
HETATM   13  O1  UNL     1       1.034  -0.622   0.086  1.00  0.00           O  
CONECT    1    2    2    2
CONECT    2    3
CONECT    3    4    6    8   10
CONECT    3   12
CONECT    4    5    5    5
CONECT    6    7    7    7
CONECT    8    9    9    9
CONECT   10   11   11   11
CONECT   12   13   13
END
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SMILES for HMDB0014470 (Nitroprusside)

O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
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INCHI for HMDB0014470 (Nitroprusside)

InChI=1S/5CN.Fe.NO/c5*1-2;;1-2/q;;;;;2*-1
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View in JSmolView Stereo Labels
Synonyms
ValueSource
[Fe(CN)5(no)](2-)ChEBI
NitroferricyanideChEBI
Pentacyanidonitrosylferrate(2-)Kegg
Pentacyanidonitrosylferric acid(2-)Generator
Chemical FormulaC5FeN6O
Average Molecular Weight215.938
Monoisotopic Molecular Weight215.948300785
IUPAC Namepentacyano(nitroso)irondiuide
Traditional Namenitroprusside
CAS Registry Number15078-28-1
SMILES
O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
InChI Identifier
InChI=1S/5CN.Fe.NO/c5*1-2;;1-2/q;;;;;2*-1
InChI KeyASPOIVQEUUCDQT-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as organic transition metal salts. These are organic salt compounds containing a transition metal atom in its ionic form.
KingdomOrganic compounds
Super ClassOrganic salts
ClassOrganic metal salts
Sub ClassOrganic transition metal salts
Direct ParentOrganic transition metal salts
Alternative Parents
Substituents
  • Organic transition metal salt
  • Organic nitrogen compound
  • Organic oxygen compound
  • Organopnictogen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organonitrogen compound
  • Organometallic compound
  • Organic transition metal moeity
  • Organic anion
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
Physiological effectNot Available
Disposition
Biological location
ProcessNot Available
Role
Indirect biological role
Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
PropertyValueSource
logP0.071ChemAxon
pKa (Strongest Basic)-3.3ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area148.38 ŲChemAxon
Rotatable Bond Count1ChemAxon
Refractivity39.44 m³·mol⁻¹ChemAxon
Polarizability16.52 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
AllCCS[M+H]+133.532859911
AllCCS[M+H-H2O]+130.432859911
AllCCS[M+NH4]+136.432859911
AllCCS[M+Na]+137.232859911
AllCCS[M-H]-123.632859911
AllCCS[M+Na-2H]-124.632859911
AllCCS[M+HCOO]-125.832859911

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
NitroprussideO=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N2224.9Standard polar33892256
NitroprussideO=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N1504.2Standard non polar33892256
NitroprussideO=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N1429.2Semi standard non polar33892256
Spectra

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Nitroprusside 10V, Positive-QTOFsplash10-014i-0090000000-5ba4626d0e175ef0de842016-06-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Nitroprusside 20V, Positive-QTOFsplash10-014i-0090000000-5ba4626d0e175ef0de842016-06-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Nitroprusside 40V, Positive-QTOFsplash10-014i-0090000000-5ba4626d0e175ef0de842016-06-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Nitroprusside 10V, Negative-QTOFsplash10-03di-0090000000-7e8d649dd353ce7c7dfd2016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Nitroprusside 20V, Negative-QTOFsplash10-03di-0090000000-7e8d649dd353ce7c7dfd2016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Nitroprusside 40V, Negative-QTOFsplash10-03di-0090000000-7e8d649dd353ce7c7dfd2016-08-03Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Membrane
Biospecimen Locations
  • Blood
  • Urine
Tissue LocationsNot Available
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodExpected but not QuantifiedNot QuantifiedNot AvailableNot AvailableTaking drug identified by DrugBank entry DB00325 details
UrineExpected but not QuantifiedNot QuantifiedNot AvailableNot AvailableTaking drug identified by DrugBank entry DB00325 details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDDB00325
Phenol Explorer Compound IDNot Available
FooDB IDNot Available
KNApSAcK IDNot Available
Chemspider ID21607452
KEGG Compound IDC07269
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkSodium nitroprusside
METLIN IDNot Available
PubChem CompoundNot Available
PDB IDNot Available
ChEBI ID7596
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available

Enzymes

Enzyme Details
1. Atrial natriuretic peptide receptor 1
General function:
Involved in phosphorus-oxygen lyase activity
Specific function:
Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Gene Name:
NPR1
Uniprot ID:
P16066
Molecular weight:
118918.11
References
  1. Fortin Y, De Lean A: Role of cyclic GMP and calcineurin in homologous and heterologous desensitization of natriuretic peptide receptor-A. Can J Physiol Pharmacol. 2006 May;84(5):539-46. [PubMed:16902599 ]
  2. Madhani M, Okorie M, Hobbs AJ, MacAllister RJ: Reciprocal regulation of human soluble and particulate guanylate cyclases in vivo. Br J Pharmacol. 2006 Nov;149(6):797-801. Epub 2006 Oct 3. [PubMed:17016498 ]
  3. Steinmetz M, Potthast R, Sabrane K, Kuhn M: Diverging vasorelaxing effects of C-type natriuretic peptide in renal resistance arteries and aortas of GC-A-deficient mice. Regul Pept. 2004 Jun 15;119(1-2):31-7. [PubMed:15093694 ]
Enzyme Details
2. Cytochrome P450 1A1
General function:
Involved in monooxygenase activity
Specific function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Gene Name:
CYP1A1
Uniprot ID:
P04798
Molecular weight:
58164.815
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Enzyme Details
3. Cytochrome P450 1A2
General function:
Involved in monooxygenase activity
Specific function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Gene Name:
CYP1A2
Uniprot ID:
P05177
Molecular weight:
58406.915
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]