Human Metabolome Database Version 3.5

Showing metabocard for D-Mannose (HMDB00169)

Record Information
Version 3.5
Creation Date 2005-11-16 08:48:42 -0700
Update Date 2013-05-29 13:24:56 -0600
HMDB ID HMDB00169
Secondary Accession Numbers None
Metabolite Identification
Common Name D-Mannose
Description D-Mannose is a carbohydrate. High-mannose-type oligosaccharides have been shown to play important roles in protein quality control. Several intracellular proteins, such as lectins, chaperones and glycan-processing enzymes, are involved in this process. These include calnexin/calreticulin, UDP-glucose:glycoprotein glucosyltransferase (UGGT), cargo receptors (such as VIP36 and ERGIC-53), mannosidase-like proteins (e.g. EDEM and Htm1p) and ubiquitin ligase (Fbs). They are thought to recognize high-mannose-type glycans with subtly different structures. Mannose-binding lectin (MBL) is an important constituent of the innate immune system. This protein binds through multiple lectin domains to the repeating sugar arrays that decorate many microbial surfaces, and is then able to activate the complement system through a specific protease called MBL-associated protease-2. The primary pathway for the formation of L-fucose in procaryotic and eucaryotic cells is from D-mannose via an internal oxidation reduction and then epimerization of GDP-D-mannose to produce GDP-L-fucose. (PMID: 9488699 Link_out, 16154739 Link_out, 11414367 Link_out).
Structure Thumb
Download: MOL | SDF | PDB | SMILES | InChI
Display: 2D Structure | 3D Structure
Synonyms
  1. (+)-mannose
  2. (+-)-mannose
  3. Carubinose
  4. D(+)-Mannose
  5. D-Mannopyranose
  6. D-Mannose
  7. DL-mannose
  8. Mannose
  9. Seminose
Chemical Formula C6H12O6
Average Molecular Weight 180.1559
Monoisotopic Molecular Weight 180.063388116
IUPAC Name (3S,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Traditional IUPAC Name D-mannose
CAS Registry Number 3458-28-4
SMILES OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O
InChI Identifier InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1
InChI Key WQZGKKKJIJFFOK-QTVWNMPRSA-N
Chemical Taxonomy
Kingdom Organic Compounds
Super Class Carbohydrates and Carbohydrate Conjugates
Class Monosaccharides
Sub Class Hexoses
Other Descriptors
  • Aliphatic Heteromonocyclic Compounds
  • Carbohydrates and Carbohydrate Conjugates
  • D-galactopyranose(ChEBI)
Substituents
  • 1,2 Diol
  • Hemiacetal
  • Oxane
  • Primary Alcohol
  • Secondary Alcohol
Direct Parent Hexoses
Ontology
Status Detected and Quantified
Origin
  • Endogenous
Biofunction
  • Component of High-mannose type N-glycan biosynthesis
  • Component of N-Glycan biosynthesis
Application Not Available
Cellular locations
  • Cytoplasm
  • Extracellular
  • Lysosome
  • Endoplasmic reticulum
  • Golgi apparatus
Physical Properties
State Solid
Experimental Properties
Property Value Reference
Melting Point 132 °C Not Available
Boiling Point Not Available Not Available
Water Solubility 713.0 mg/mL at 17 °C Not Available
LogP Not Available Not Available
Predicted Properties
Property Value Source
Water Solubility 782 g/L ALOGPS
LogP -2.57 ALOGPS
LogP -2.9 ChemAxon
LogS 0.64 ALOGPS
pKa (strongest acidic) 11.3 ChemAxon
pKa (strongest basic) -3 ChemAxon
Hydrogen Acceptor Count 6 ChemAxon
Hydrogen Donor Count 5 ChemAxon
Polar Surface Area 110.38 A2 ChemAxon
Rotatable Bond Count 1 ChemAxon
Refractivity 35.92 ChemAxon
Polarizability 16.14 ChemAxon
Formal Charge 0 ChemAxon
Physiological Charge 0 ChemAxon
Spectra
Gas-MS Spectrum
1H NMR Spectrum
13C NMR Spectrum
MS/MS Spectrum Quattro_QQQ 10
MS/MS Spectrum Quattro_QQQ 25
MS/MS Spectrum GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)
MS/MS Spectrum GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)
MS/MS Spectrum GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)
MS/MS Spectrum GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)
MS/MS Spectrum GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)
MS/MS Spectrum GC-MS
MS/MS Spectrum GC-MS
[1H,13C] 2D NMR Spectrum
Biological Properties
Cellular Locations
  • Cytoplasm
  • Extracellular
  • Lysosome
  • Endoplasmic reticulum
  • Golgi apparatus
Biofluid Locations
  • Blood
  • Breast Milk
  • Cerebrospinal Fluid (CSF)
  • Urine
Tissue Location
  • Muscle
  • Bladder
  • Fibroblasts
  • Intestine
  • Pancreas
  • Placenta
  • Testes
  • Kidney
  • Epidermis
  • Myelin
  • Prostate
  • Adrenal Medulla
  • Spleen
Pathways
Name SMPDB Link KEGG Link
Fructose and Mannose Degradation SMP00064 map00051 Link_out
Galactose Metabolism SMP00043 map00052 Link_out
Normal Concentrations
Biofluid Status Value Age Sex Condition Reference
Blood Detected and Quantified
39.0 +/- 7.0 uM Adult (>18 years old) Both Normal
  • Geigy Scient...
Blood Detected and Quantified
64.0 +/- 12.0 uM Adult (>18 years old) Male Normal
  • Geigy Scient...
Breast Milk Detected and Quantified
66.4 +/- 2.3 uM Adult (>18 years old) Female Normal
Cerebrospinal Fluid (CSF) Detected and Quantified
64.0 (56.0-72.0) uM Adult (>18 years old) Both Normal
  • Geigy Scient...
Cerebrospinal Fluid (CSF) Detected and Quantified
24 +/- 13 uM Not Specified Both Normal
Urine Detected and Quantified
11.65 +/- 15.42 umol/mmol creatinine Infant (0-1 year old) Both Normal
Urine Detected and Quantified
2.5 (0.0-12.6) umol/mmol creatinine Newborn (0-30 days old) Both Normal
  • Geigy Scient...
Urine Detected and Quantified
1.25 (0.0-2.5) umol/mmol creatinine Adult (>18 years old) Both Normal
  • Geigy Scient...
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease References None
Associated OMIM IDs None
DrugBank ID DB02944 Link_out
DrugBank Metabolite ID Not Available
Phenol Explorer Compound ID Not Available
Phenol Explorer Metabolite ID Not Available
FoodDB ID FDB001202
KNApSAcK ID Not Available
Chemspider ID 17893 Link_out
KEGG Compound ID C00159 Link_out
BioCyc ID MANNOSE Link_out
BiGG ID 34085 Link_out
Wikipedia Link D-Mannose Link_out
NuGOwiki Link HMDB00169 Link_out
Metagene Link HMDB00169 Link_out
METLIN ID Not Available
PubChem Compound 18950 Link_out
PDB ID Not Available
ChEBI ID 4208 Link_out
References
Synthesis Reference Sowden, John C.; Fischer, Hermann O. L. Condensation of nitromethane with D- and L-arabinose: preparation of L-glucose and L-mannose. Journal of the American Chemical Society (1947), 69 1963-5.
Material Safety Data Sheet (MSDS) Download (PDF)
General References
  1. Lee SH, Nam SY, Chung BC: Altered profile of endogenous steroids in the urine of patients with prolactinoma. Clin Biochem. 1998 Oct;31(7):529-35. Pubmed: 9812172 Link_out
  2. Nakagawa F, Schulte BA, Spicer SS: Lectin cytochemical evaluation of somatosensory neurons and their peripheral and central processes in rat and man. Cell Tissue Res. 1986;245(3):579-89. Pubmed: 3757018 Link_out
  3. Thio CL, Mosbruger T, Astemborski J, Greer S, Kirk GD, O'Brien SJ, Thomas DL: Mannose binding lectin genotypes influence recovery from hepatitis B virus infection. J Virol. 2005 Jul;79(14):9192-6. Pubmed: 15994813 Link_out
  4. Otter M, Zockova P, Kuiper J, van Berkel TJ, Barrett-Bergshoeff MM, Rijken DC: Isolation and characterization of the mannose receptor from human liver potentially involved in the plasma clearance of tissue-type plasminogen activator. Hepatology. 1992 Jul;16(1):54-9. Pubmed: 1618483 Link_out
  5. Hu P, Parenti G, Keulemans J, Hoogeveen AT: Lysosomal tartrate sensitive acid phosphatase deficiency in cells which contain lysosomal "high uptake forms". Biochem Biophys Res Commun. 1990 Mar 16;167(2):520-7. Pubmed: 2322240 Link_out
  6. Hermentin P, Witzel R, Kanzy EJ, Diderrich G, Hoffmann D, Metzner H, Vorlop J, Haupt H: The hypothetical N-glycan charge: a number that characterizes protein glycosylation. Glycobiology. 1996 Mar;6(2):217-30. Pubmed: 8727793 Link_out
  7. DeRossi C, Bode L, Eklund EA, Zhang F, Davis JA, Westphal V, Wang L, Borowsky AD, Freeze HH: Ablation of mouse phosphomannose isomerase (Mpi) causes mannose 6-phosphate accumulation, toxicity, and embryonic lethality. J Biol Chem. 2006 Mar 3;281(9):5916-27. Epub 2005 Dec 8. Pubmed: 16339137 Link_out
  8. Miras MT, Aunis D, Mandel P: Studies on the interaction of dopamine beta-hydroxylase from various sources with phytohaemagglutinins. Clin Chim Acta. 1975 Nov 3;64(3):293-302. Pubmed: 1183043 Link_out
  9. Van der Ploeg AT, Kroos MA, Willemsen R, Brons NH, Reuser AJ: Intravenous administration of phosphorylated acid alpha-glucosidase leads to uptake of enzyme in heart and skeletal muscle of mice. J Clin Invest. 1991 Feb;87(2):513-8. Pubmed: 1991835 Link_out
  10. Cavallone D, Malagolini N, Monti A, Wu XR, Serafini-Cessi F: Variation of high mannose chains of Tamm-Horsfall glycoprotein confers differential binding to type 1-fimbriated Escherichia coli. J Biol Chem. 2004 Jan 2;279(1):216-22. Epub 2003 Oct 21. Pubmed: 14570881 Link_out
  11. Adlerberth I, Ahrne S, Johansson ML, Molin G, Hanson LA, Wold AE: A mannose-specific adherence mechanism in Lactobacillus plantarum conferring binding to the human colonic cell line HT-29. Appl Environ Microbiol. 1996 Jul;62(7):2244-51. Pubmed: 8779562 Link_out
  12. Hung CS, Bouckaert J, Hung D, Pinkner J, Widberg C, DeFusco A, Auguste CG, Strouse R, Langermann S, Waksman G, Hultgren SJ: Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol Microbiol. 2002 May;44(4):903-15. Pubmed: 12010488 Link_out
  13. Condaminet B, Peguet-Navarro J, Stahl PD, Dalbiez-Gauthier C, Schmitt D, Berthier-Vergnes O: Human epidermal Langerhans cells express the mannose-fucose binding receptor. Eur J Immunol. 1998 Nov;28(11):3541-51. Pubmed: 9842897 Link_out
  14. Go S, Sato C, Furuhata K, Kitajima K: Oral ingestion of mannose alters the expression level of deaminoneuraminic acid (KDN) in mouse organs. Glycoconj J. 2006 Jul;23(5-6):411-21. Pubmed: 16897182 Link_out
  15. Burk MR, Troeger C, Brinkhaus R, Holzgreve W, Hahn S: Severely reduced presence of tissue macrophages in the basal plate of pre-eclamptic placentae. Placenta. 2001 Apr;22(4):309-16. Pubmed: 11286566 Link_out
  16. Sarkar K, Das PK: Protective effect of neoglycoprotein-conjugated muramyl dipeptide against Leishmania donovani infection: the role of cytokines. J Immunol. 1997 Jun 1;158(11):5357-65. Pubmed: 9164956 Link_out
  17. Kusmierz J, DeGeorge JJ, Sweeney D, May C, Rapoport SI: Quantitative analysis of polyols in human plasma and cerebrospinal fluid. J Chromatogr. 1989 Dec 29;497:39-48. Pubmed: 2625478 Link_out
  18. Biessen EA, Noorman F, van Teijlingen ME, Kuiper J, Barrett-Bergshoeff M, Bijsterbosch MK, Rijken DC, van Berkel TJ: Lysine-based cluster mannosides that inhibit ligand binding to the human mannose receptor at nanomolar concentration. J Biol Chem. 1996 Nov 8;271(45):28024-30. Pubmed: 8910412 Link_out
  19. Smith ME: Phagocytic properties of microglia in vitro: implications for a role in multiple sclerosis and EAE. Microsc Res Tech. 2001 Jul 15;54(2):81-94. Pubmed: 11455615 Link_out
  20. Della Porta M, Danova M, Rigolin GM, Brugnatelli S, Rovati B, Tronconi C, Fraulini C, Russo Rossi A, Riccardi A, Castoldi G: Dendritic cells and vascular endothelial growth factor in colorectal cancer: correlations with clinicobiological findings. Oncology. 2005;68(2-3):276-84. Epub 2005 Jul 7. Pubmed: 16015045 Link_out
  21. Patnaik SK, Stanley P: Mouse large can modify complex N- and mucin O-glycans on alpha-dystroglycan to induce laminin binding. J Biol Chem. 2005 May 27;280(21):20851-9. Epub 2005 Mar 23. Pubmed: 15788414 Link_out
  22. Shoemaker JD, Elliott WH: Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease. J Chromatogr. 1991 Jan 2;562(1-2):125-38. Pubmed: 2026685 Link_out
  23. Brysk MM, Miller J: Concanavalin A binding glycoprotein in human stratum corneum. J Invest Dermatol. 1984 Mar;82(3):280-2. Pubmed: 6421939 Link_out
  24. Takahashi I, Takahashi T, Mikami T, Komatsu M, Ohura T, Schuchman EH, Takada G: Acid sphingomyelinase: relation of 93lysine residue on the ratio of intracellular to secreted enzyme activity. Tohoku J Exp Med. 2005 Aug;206(4):333-40. Pubmed: 15997205 Link_out
  25. Wu X, Rush JS, Karaoglu D, Krasnewich D, Lubinsky MS, Waechter CJ, Gilmore R, Freeze HH: Deficiency of UDP-GlcNAc:Dolichol Phosphate N-Acetylglucosamine-1 Phosphate Transferase (DPAGT1) causes a novel congenital disorder of Glycosylation Type Ij. Hum Mutat. 2003 Aug;22(2):144-50. Pubmed: 12872255 Link_out
  26. Akazawa S, Metzger BE, Freinkel N: Relationships between glucose and mannose during late gestation in normal pregnancy and pregnancy complicated by diabetes mellitus: concurrent concentrations in maternal plasma and amniotic fluid. J Clin Endocrinol Metab. 1986 May;62(5):984-9. Pubmed: 3958133 Link_out
  27. Blach-Olszewska Z: Innate immunity: cells, receptors, and signaling pathways. Arch Immunol Ther Exp (Warsz). 2005 May-Jun;53(3):245-53. Pubmed: 15995585 Link_out
  28. Pietila EM, Tuusa JT, Apaja PM, Aatsinki JT, Hakalahti AE, Rajaniemi HJ, Petaja-Repo UE: Inefficient maturation of the rat luteinizing hormone receptor. A putative way to regulate receptor numbers at the cell surface. J Biol Chem. 2005 Jul 15;280(28):26622-9. Epub 2005 May 18. Pubmed: 15901736 Link_out
  29. Carchon HA, Jaeken J: Determination of D-mannose in serum by capillary electrophoresis. Clin Chem. 2001;47(7):1319-21. Pubmed: 11427470 Link_out
  30. Alton G, Hasilik M, Niehues R, Panneerselvam K, Etchison JR, Fana F, Freeze HH: Direct utilization of mannose for mammalian glycoprotein biosynthesis. Glycobiology. 1998 Mar;8(3):285-95. Pubmed: 9451038 Link_out
  31. Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. Pubmed: 19212411 Link_out
  32. Park SH, Pastuszak I, Drake R, Elbein AD: Purification to apparent homogeneity and properties of pig kidney L-fucose kinase. J Biol Chem. 1998 Mar 6;273(10):5685-91. Pubmed: 9488699 Link_out
  33. Ito Y, Hagihara S, Matsuo I, Totani K: Structural approaches to the study of oligosaccharides in glycoprotein quality control. Curr Opin Struct Biol. 2005 Oct;15(5):481-9. Pubmed: 16154739 Link_out
  34. Jack DL, Klein NJ, Turner MW: Mannose-binding lectin: targeting the microbial world for complement attack and opsonophagocytosis. Immunol Rev. 2001 Apr;180:86-99. Pubmed: 11414367 Link_out

Enzymes
Name: Phospholipase A2
Reactions: Not Available
Gene Name: PLA2G1B
Uniprot ID: P04054 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Prostatic acid phosphatase
Reactions: Not Available
Gene Name: ACPP
Uniprot ID: P15309 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Glucokinase
Reactions: Not Available
Gene Name: GCK
Uniprot ID: P35557 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Hexokinase-3
Reactions:
Adenosine triphosphate + D-Mannose unknown ADP + Mannose 6-phosphate details
Gene Name: HK3
Uniprot ID: P52790 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Hexokinase-2
Reactions:
Adenosine triphosphate + D-Mannose unknown ADP + Mannose 6-phosphate details
Gene Name: HK2
Uniprot ID: P52789 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Hexokinase-1
Reactions:
Adenosine triphosphate + D-Mannose unknown ADP + Mannose 6-phosphate details
Gene Name: HK1
Uniprot ID: P19367 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Lactase-phlorizin hydrolase
Reactions: Not Available
Gene Name: LCT
Uniprot ID: P09848 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Deoxyribonuclease-1
Reactions: Not Available
Gene Name: DNASE1
Uniprot ID: P24855 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Liver carboxylesterase 1
Reactions: Not Available
Gene Name: CES1
Uniprot ID: P23141 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cholinesterase
Reactions: Not Available
Gene Name: BCHE
Uniprot ID: P06276 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Alpha-galactosidase A
Reactions:
Epimelibiose + Water unknown D-Mannose + Beta-D-Galactose details
Gene Name: GLA
Uniprot ID: P06280 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Beta-glucuronidase
Reactions: Not Available
Gene Name: GUSB
Uniprot ID: P08236 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Alpha-mannosidase 2
Reactions:
+ Water unknown + D-Mannose details
Gene Name: MAN2A1
Uniprot ID: Q16706 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB
Reactions:
+ Water unknown + D-Mannose details
Water + unknown D-Mannose + details
Gene Name: MAN1A2
Uniprot ID: O60476 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Reactions:
+ Water unknown + D-Mannose details
Water + unknown D-Mannose + details
Gene Name: MAN1B1
Uniprot ID: Q9UKM7 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA
Reactions:
+ Water unknown + D-Mannose details
Water + unknown D-Mannose + details
Gene Name: MAN1A1
Uniprot ID: P33908 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Nitric oxide synthase, brain
Reactions: Not Available
Gene Name: NOS1
Uniprot ID: P29475 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Prostaglandin G/H synthase 1
Reactions: Not Available
Gene Name: PTGS1
Uniprot ID: P23219 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Polypeptide N-acetylgalactosaminyltransferase 1
Reactions: Not Available
Gene Name: GALNT1
Uniprot ID: Q10472 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Insulin-like growth factor 1 receptor
Reactions: Not Available
Gene Name: IGF1R
Uniprot ID: P08069 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Lysozyme C
Reactions: Not Available
Gene Name: LYZ
Uniprot ID: P61626 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase
Reactions: Not Available
Gene Name: ALG3
Uniprot ID: Q92685 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Dipeptidyl peptidase 4
Reactions: Not Available
Gene Name: DPP4
Uniprot ID: P27487 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cytokine receptor common subunit beta
Reactions: Not Available
Gene Name: CSF2RB
Uniprot ID: P32927 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Heparin cofactor 2
Reactions: Not Available
Gene Name: SERPIND1
Uniprot ID: P05546 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Beta-2-glycoprotein 1
Reactions: Not Available
Gene Name: APOH
Uniprot ID: P02749 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Antithrombin-III
Reactions: Not Available
Gene Name: SERPINC1
Uniprot ID: P01008 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cation-independent mannose-6-phosphate receptor
Reactions: Not Available
Gene Name: IGF2R
Uniprot ID: P11717 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Glycophorin-B
Reactions: Not Available
Gene Name: GYPB
Uniprot ID: P06028 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Zinc-alpha-2-glycoprotein
Reactions: Not Available
Gene Name: AZGP1
Uniprot ID: P25311 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Lactotransferrin
Reactions: Not Available
Gene Name: LTF
Uniprot ID: P02788 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Low-density lipoprotein receptor
Reactions: Not Available
Gene Name: LDLR
Uniprot ID: P01130 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Rhodopsin
Reactions: Not Available
Gene Name: RHO
Uniprot ID: P08100 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Alpha-amylase 2B
Reactions: Not Available
Gene Name: AMY2B
Uniprot ID: P19961 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cathepsin D
Reactions: Not Available
Gene Name: CTSD
Uniprot ID: P07339 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Galectin-1
Reactions: Not Available
Gene Name: LGALS1
Uniprot ID: P09382 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Sialic acid-binding Ig-like lectin 7
Reactions: Not Available
Gene Name: SIGLEC7
Uniprot ID: Q9Y286 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Mannose-binding protein C
Reactions: Not Available
Gene Name: MBL2
Uniprot ID: P11226 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Granzyme B
Reactions: Not Available
Gene Name: GZMB
Uniprot ID: P10144 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: CD209 antigen
Reactions: Not Available
Gene Name: CD209
Uniprot ID: Q9NNX6 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Interferon beta precursor
Reactions: Not Available
Gene Name: IFNB1
Uniprot ID: P01574 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC
Reactions:
+ Water unknown + D-Mannose details
Water + unknown D-Mannose + details
Gene Name: MAN1C1
Uniprot ID: Q9NR34 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Complement C1r subcomponent
Reactions: Not Available
Gene Name: C1R
Uniprot ID: P00736 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Atrial natriuretic peptide receptor 3
Reactions: Not Available
Gene Name: NPR3
Uniprot ID: P17342 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: N-acetylglucosamine-1-phosphotransferase subunits alpha/beta
Reactions: Not Available
Gene Name: GNPTAB
Uniprot ID: Q3T906 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Carboxypeptidase D
Reactions: Not Available
Gene Name: CPD
Uniprot ID: O75976 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Putative hexokinase HKDC1
Reactions:
Adenosine triphosphate + D-Mannose unknown ADP + Mannose 6-phosphate details
Gene Name: HKDC1
Uniprot ID: Q2TB90 Link_out
Protein Sequence: FASTA
Name: Alpha-mannosidase 2x
Reactions:
+ Water unknown + D-Mannose details
Gene Name: MAN2A2
Uniprot ID: P49641 Link_out
Protein Sequence: FASTA
Name: Lysosomal alpha-mannosidase
Reactions:
+ Water unknown + D-Mannose details
+ Water unknown + D-Mannose details
Gene Name: MAN2B1
Uniprot ID: O00754 Link_out
Protein Sequence: FASTA
Name: Epididymis-specific alpha-mannosidase
Reactions:
+ Water unknown + D-Mannose details
+ Water unknown + D-Mannose details
Gene Name: MAN2B2
Uniprot ID: Q9Y2E5 Link_out
Protein Sequence: FASTA