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Record Information
Creation Date2005-11-16 15:48:42 UTC
Update Date2016-02-11 01:02:14 UTC
Secondary Accession Numbers
  • HMDB00835
Metabolite Identification
Common NameN-Acetylgalactosamine
DescriptionAcetylgalactosamine is an important constituent of brain heteropolysaccharides (glycoproteins). The concentration of the N-acetylgalactosamine-containing glycoproteins in the 3-year-old cerebral gray matter from human brain is 7-15 times greater than in 8-year old tissue and 15-30 times greater than in 72-year-old tissue. (PMID 1207868 ). Acetylgalactosamine patterns of the composition of the soluble glycoproteins from endoscopic mucosal biopsies tends to decrease in the tumor area in cancer of the stomach (compared with the antrum and corpus of control stomachs). (PMID: 7151277 ). Chondroitin 6-sulfotransferase (C6ST) is the key enzyme in the biosynthesis of chondroitin 6-sulfate, a glycosaminoglycan implicated in chondrogenesis, neoplasia, atherosclerosis, and other processes. C6ST catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to carbon 6 of the N- Acetylgalactosamine residues of chondroitin. (PMID: 9639683 ).
  1. 2-Acetamido-2-deoxy-a-D-allopyranose
  2. 2-Acetamido-2-deoxy-a-D-glucopyranose
  3. 2-Acetamido-2-deoxy-alpha-D-allopyranose
  4. 2-Acetamido-2-deoxy-alpha-D-glucopyranose
  5. 2-Acetamido-2-deoxy-alpha-delta-allopyranose
  6. 2-Acetamido-2-deoxy-alpha-delta-glucopyranose
  7. 2-Acetamido-2-deoxy-b-D-glucopyranose
  8. 2-Acetamido-2-deoxy-beta-D-glucopyranose
  9. 2-Acetamido-2-deoxy-beta-delta-glucopyranose
  10. 2-Acetamido-2-desoxy-b-D-talofuranose
  11. 2-Acetamido-2-desoxy-beta-D-talofuranose
  12. 2-Acetamido-2-desoxy-beta-delta-talofuranose
  13. 2-Acetamino-2-deoxy-a-D-glucose
  14. 2-Acetamino-2-deoxy-alpha-D-glucose
  15. 2-Acetamino-2-deoxy-alpha-delta-glucose
  16. 2-Acetamino-2-desoxy-a-D-glucopyranose
  17. 2-Acetamino-2-desoxy-alpha-D-glucopyranose
  18. 2-Acetamino-2-desoxy-alpha-delta-glucopyranose
  19. 2-Acetamino-2-desoxy-D-galaktose
  20. 2-Acetamino-2-desoxy-D-glucose
  21. 2-Acetamino-2-desoxy-delta-galaktose
  22. 2-Acetamino-2-desoxy-delta-glucose
  23. 2-Acetylamino-2-deoxy-a-D-galactopyranose
  24. 2-Acetylamino-2-deoxy-a-D-glucopyranose
  25. 2-Acetylamino-2-deoxy-a-D-mannopyranose
  26. 2-Acetylamino-2-deoxy-alpha-D-galactopyranose
  27. 2-Acetylamino-2-deoxy-alpha-D-glucopyranose
  28. 2-Acetylamino-2-deoxy-alpha-D-mannopyranose
  29. 2-Acetylamino-2-deoxy-alpha-delta-galactopyranose
  30. 2-Acetylamino-2-deoxy-alpha-delta-glucopyranose
  31. 2-Acetylamino-2-deoxy-alpha-delta-mannopyranose
  32. 2-Acetylamino-2-deoxy-b-D-allopyranose
  33. 2-Acetylamino-2-deoxy-b-D-altropyranose
  34. 2-Acetylamino-2-deoxy-b-D-galactopyranose
  35. 2-Acetylamino-2-deoxy-b-D-glucopyranose
  36. 2-Acetylamino-2-deoxy-b-D-mannopyranose
  37. 2-Acetylamino-2-deoxy-beta-D-allopyranose
  38. 2-Acetylamino-2-deoxy-beta-D-altropyranose
  39. 2-Acetylamino-2-deoxy-beta-D-galactopyranose
  40. 2-Acetylamino-2-deoxy-beta-D-glucopyranose
  41. 2-Acetylamino-2-deoxy-beta-D-mannopyranose
  42. 2-Acetylamino-2-deoxy-beta-delta-allopyranose
  43. 2-Acetylamino-2-deoxy-beta-delta-altropyranose
  44. 2-Acetylamino-2-deoxy-beta-delta-galactopyranose
  45. 2-Acetylamino-2-deoxy-beta-delta-glucopyranose
  46. 2-Acetylamino-2-deoxy-beta-delta-mannopyranose
  47. 2-Acetylamino-2-desoxy-a-D-galaktose
  48. 2-Acetylamino-2-desoxy-a-D-mannose
  49. 2-Acetylamino-2-desoxy-alpha-D-galaktose
  50. 2-Acetylamino-2-desoxy-alpha-D-mannose
  51. 2-Acetylamino-2-desoxy-alpha-delta-galaktose
  52. 2-Acetylamino-2-desoxy-alpha-delta-mannose
  53. 2-Acetylamino-2-desoxy-b-D-galaktose
  54. 2-Acetylamino-2-desoxy-b-D-mannose
  55. 2-Acetylamino-2-desoxy-beta-D-galaktose
  56. 2-Acetylamino-2-desoxy-beta-D-mannose
  57. 2-Acetylamino-2-desoxy-beta-delta-galaktose
  58. 2-Acetylamino-2-desoxy-beta-delta-mannose
  59. 2-Acetylamino-2-desoxy-D-mannose
  60. 2-Acetylamino-2-desoxy-delta-mannose
  61. 2-Acetylamino-2-desoxy-DL-glucopyranose
  62. 2-Acetylamino-a-D-2-deoxy-galactopyranose
  63. 2-Acetylamino-a-D-2-deoxy-glucopyranose
  64. 2-Acetylamino-a-D-2-deoxy-glucose
  65. 2-Acetylamino-a-D-2-deoxy-mannopyranose
  66. 2-Acetylamino-alpha-D-2-deoxy-galactopyranose
  67. 2-Acetylamino-alpha-D-2-deoxy-glucopyranose
  68. 2-Acetylamino-alpha-D-2-deoxy-glucose
  69. 2-Acetylamino-alpha-D-2-deoxy-mannopyranose
  70. 2-Acetylamino-alpha-delta-2-deoxy-galactopyranose
  71. 2-Acetylamino-alpha-delta-2-deoxy-glucopyranose
  72. 2-Acetylamino-alpha-delta-2-deoxy-glucose
  73. 2-Acetylamino-alpha-delta-2-deoxy-mannopyranose
  74. 2-Acetylamino-b-D-2-deoxy-galactopyranose
  75. 2-Acetylamino-b-D-2-deoxy-glucopyranose
  76. 2-Acetylamino-b-D-2-deoxy-mannopyranose
  77. 2-Acetylamino-beta-D-2-deoxy-galactopyranose
  78. 2-Acetylamino-beta-D-2-deoxy-glucopyranose
  79. 2-Acetylamino-beta-D-2-deoxy-mannopyranose
  80. 2-Acetylamino-beta-delta-2-deoxy-galactopyranose
  81. 2-Acetylamino-beta-delta-2-deoxy-glucopyranose
  82. 2-Acetylamino-beta-delta-2-deoxy-mannopyranose
  83. 2-Acetylamino-D-2-deoxy-galactose
  84. 2-Acetylamino-D-2-deoxy-glucose
  85. 2-Acetylamino-D-2-deoxy-gulose
  86. 2-Acetylamino-D-2-deoxy-idose
  87. 2-Acetylamino-D-2-deoxy-mannose
  88. 2-Acetylamino-D-2-deoxy-talose
  89. 2-Acetylamino-delta-2-deoxy-galactose
  90. 2-Acetylamino-delta-2-deoxy-glucose
  91. 2-Acetylamino-delta-2-deoxy-gulose
  92. 2-Acetylamino-delta-2-deoxy-idose
  93. 2-Acetylamino-delta-2-deoxy-mannose
  94. 2-Acetylamino-delta-2-deoxy-talose
  95. 2-Acetylamino-L-2-deoxy-galactose
  96. 2-Acetylamino-L-2-deoxy-mannose
  97. a-2-Acetamido-2-deoxy-D-galactose
  98. alpha-2-Acetamido-2-deoxy-D-galactose
  99. alpha-2-Acetamido-2-deoxy-delta-galactose
  100. GalNAc
  101. N-(2,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl)-acetamide
  102. N-Acetyl-a-D-glucosamine
  103. N-Acetyl-alpha-D-glucosamine
  104. N-Acetyl-alpha-delta-glucosamine
  105. N-Acetyl-D-allosamine
  106. N-Acetyl-D-galactosamine
  107. N-Acetyl-delta-allosamine
  108. N-Acetyl-delta-galactosamine
  109. N-Acetylgalactosamin
  110. N-Acetylgalactosamine
  111. N-Acetylglucosamin
  112. N-Acetylgluosamin
  113. N-Acetylmannosamin
Chemical FormulaC8H15NO6
Average Molecular Weight221.2078
Monoisotopic Molecular Weight221.089937217
IUPAC NameN-[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
Traditional Nameα-GalNAc
CAS Registry Number1811-31-0
InChI Identifier
Chemical Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as acylaminosugars. These are organic compounds containing a sugar linked to a chain through N-acyl group.
KingdomOrganic compounds
Super ClassOrganooxygen compounds
ClassCarbohydrates and carbohydrate conjugates
Sub ClassAminosaccharides
Direct ParentAcylaminosugars
Alternative Parents
  • Acylaminosugar
  • N-acyl-alpha-hexosamine
  • Oxane
  • Monosaccharide
  • Acetamide
  • Secondary carboxylic acid amide
  • Secondary alcohol
  • Polyol
  • Hemiacetal
  • Carboxamide group
  • 1,2-diol
  • Oxacycle
  • Organoheterocyclic compound
  • Carboxylic acid derivative
  • Carboxylic acid amide
  • Hydrocarbon derivative
  • Primary alcohol
  • Organonitrogen compound
  • Carbonyl group
  • Alcohol
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External Descriptors
StatusDetected but not Quantified
  • Endogenous
  • Component of Aminosugars metabolism
  • Component of Globoside metabolism
  • Component of Glutamate metabolism
  • Component of Keratan sulfate biosynthesis
  • Component of N-Glycan biosynthesis
  • Component of O-Glycan biosynthesis
ApplicationNot Available
Cellular locations
  • Lysosome
  • Golgi apparatus
Physical Properties
Experimental Properties
Melting Point172 - 173 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
Water Solubility254.0 mg/mLALOGPS
pKa (Strongest Acidic)11.6ChemAxon
pKa (Strongest Basic)-0.78ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count5ChemAxon
Polar Surface Area119.25 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity47.02 m3·mol-1ChemAxon
Polarizability20.84 Å3ChemAxon
Number of Rings1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectrum TypeDescriptionSplash Key
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-2zt0000000-f6d052d0a798e4e2edeeView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-zk00000000-8dc5f0ece3a66ea3928dView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-z200000000-23b0bbbd1c8a5ad5551eView in MoNA
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
Biological Properties
Cellular Locations
  • Lysosome
  • Golgi apparatus
Biofluid Locations
  • Saliva
Tissue Location
  • Adipose Tissue
  • Brain
  • Epidermis
  • Intestine
  • Liver
  • Muscle
  • Myelin
  • Nerve Cells
  • Neuron
  • Pancreas
  • Placenta
  • Prostate
  • Skeletal Muscle
  • Spleen
  • Testes
PathwaysNot Available
Normal Concentrations
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
SalivaDetected but not QuantifiedNot ApplicableAdult (>18 years old)Male
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDFDB021906
KNApSAcK IDNot Available
Chemspider ID76020
KEGG Compound IDC01074
BiGG ID36880
Wikipedia LinkN-Acetylgalactosamine
NuGOwiki LinkHMDB00212
Metagene LinkHMDB00212
PubChem Compound84265
ChEBI ID40356
Synthesis ReferenceCardini, C. E.; Leloir, Luis F. Enzymic formation of acetylgalactosamine. Journal of Biological Chemistry (1957), 225 317-24.
Material Safety Data Sheet (MSDS)Download (PDF)
General References
  1. Mazany KD, Peng T, Watson CE, Tabas I, Williams KJ: Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization. Biochim Biophys Acta. 1998 Jul 1;1407(1):92-7. [9639683 ]
  2. Zhang Y, Iwasaki H, Wang H, Kudo T, Kalka TB, Hennet T, Kubota T, Cheng L, Inaba N, Gotoh M, Togayachi A, Guo J, Hisatomi H, Nakajima K, Nishihara S, Nakamura M, Marth JD, Narimatsu H: Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen. J Biol Chem. 2003 Jan 3;278(1):573-84. Epub 2002 Oct 28. [12407114 ]
  3. White T, Bennett EP, Takio K, Sorensen T, Bonding N, Clausen H: Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. J Biol Chem. 1995 Oct 13;270(41):24156-65. [7592619 ]
  4. Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. [19212411 ]
  5. Nakagawa F, Schulte BA, Spicer SS: Lectin cytochemical evaluation of somatosensory neurons and their peripheral and central processes in rat and man. Cell Tissue Res. 1986;245(3):579-89. [3757018 ]
  6. Kamakura K, Kaida K, Kusunoki S, Miyamoto N, Masaki T, Nakamura R, Motoyoshi K, Fukuda J: Harmful effects of anti-GalNAc-GD1a antibodies and TNF-alpha on rat dorsal root ganglia. J Peripher Nerv Syst. 2005 Jun;10(2):190-201. [15958130 ]
  7. Petri WA Jr, Chaudhry O, Haque R, Houpt E: Adherence-blocking vaccine for amebiasis. Arch Med Res. 2006 Feb;37(2):288-91. [16380334 ]
  8. Petry K, Greinix HT, Nudelman E, Eisen H, Hakomori S, Levy HL, Reichardt JK: Characterization of a novel biochemical abnormality in galactosemia: deficiency of glycolipids containing galactose or N-acetylgalactosamine and accumulation of precursors in brain and lymphocytes. Biochem Med Metab Biol. 1991 Aug;46(1):93-104. [1931160 ]
  9. Kaida K, Kusunoki S, Kamakura K, Motoyoshi K, Kanazawa I: GalNAc-GD1a in human peripheral nerve: target sites of anti-ganglioside antibody. Neurology. 2003 Aug 26;61(4):465-70. [12939418 ]
  10. Gupta D, Sabesan S, Brewer CF: Selective inhibition of N-acetylglucosamine and galactose-specific lectins including the 14-kDa vertebrate lectin by novel synthetic biantennary oligosaccharides. Eur J Biochem. 1993 Sep 15;216(3):789-97. [8404897 ]
  11. Sutherlin ME, Nishimori I, Caffrey T, Bennett EP, Hassan H, Mandel U, Mack D, Iwamura T, Clausen H, Hollingsworth MA: Expression of three UDP-N-acetyl-alpha-D-galactosamine:polypeptide GalNAc N-acetylgalactosaminyltransferases in adenocarcinoma cell lines. Cancer Res. 1997 Nov 1;57(21):4744-8. [9354435 ]
  12. Kariniemi AL, Virtanen I: Dolichos biflorus agglutinin (DBA) reveals a similar basal cell differentiation in normal and psoriatic epidermis. Histochemistry. 1989;93(2):129-32. [2482277 ]
  13. Yuki N: Infectious origins of, and molecular mimicry in, Guillain-Barre and Fisher syndromes. Lancet Infect Dis. 2001 Aug;1(1):29-37. [11871407 ]
  14. Tao X, Gao G, Zhang HZ, Zhu DX, Boersma A, Lamblin G, Han KK: Isolation and characterization of human urinary colony-stimulating factor. Biol Chem Hoppe Seyler. 1987 Mar;368(3):187-94. [3496105 ]
  15. Hiruma T, Togayachi A, Okamura K, Sato T, Kikuchi N, Kwon YD, Nakamura A, Fujimura K, Gotoh M, Tachibana K, Ishizuka Y, Noce T, Nakanishi H, Narimatsu H: A novel human beta1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAcbeta1-3GlcNAc. J Biol Chem. 2004 Apr 2;279(14):14087-95. Epub 2004 Jan 14. [14724282 ]
  16. Chikakiyo H, Kunishige M, Yoshino H, Asano A, Sumitomo Y, Endo I, Matsumoto T, Mitsui T: Delayed motor and sensory neuropathy in a patient with brainstem encephalitis. J Neurol Sci. 2005 Jul 15;234(1-2):105-8. [15936038 ]
  17. Roelen HC, Bijsterbosch MK, Bakkeren HF, van Berkel TJ, Kempen HJ, Buytenhek M, van der Marel GA, van Boom JH: Water-soluble cholesteryl-containing phosphorothioate monogalactosides: synthesis, properties, and use in lowering blood cholesterol by directing plasma lipoproteins to the liver. J Med Chem. 1991 Mar;34(3):1036-42. [2002447 ]
  18. Smith PL, Bousfield GR, Kumar S, Fiete D, Baenziger JU: Equine lutropin and chorionic gonadotropin bear oligosaccharides terminating with SO4-4-GalNAc and Sia alpha 2,3Gal, respectively. J Biol Chem. 1993 Jan 15;268(2):795-802. [8419356 ]
  19. Szkudlinski MW, Thotakura NR, Tropea JE, Grossmann M, Weintraub BD: Asparagine-linked oligosaccharide structures determine clearance and organ distribution of pituitary and recombinant thyrotropin. Endocrinology. 1995 Aug;136(8):3325-30. [7628367 ]
  20. Taguchi K, Ren J, Utsunomiya I, Aoyagi H, Fujita N, Ariga T, Miyatake T, Yoshino H: Neurophysiological and immunohistochemical studies on Guillain-Barre syndrome with IgG anti-GalNAc-GD1a antibodies-effects on neuromuscular transmission. J Neurol Sci. 2004 Oct 15;225(1-2):91-8. [15465091 ]
  21. Hoyte K, Kang C, Martin PT: Definition of pre- and postsynaptic forms of the CT carbohydrate antigen at the neuromuscular junction: ubiquitous expression of the CT antigens and the CT GalNAc transferase in mouse tissues. Brain Res Mol Brain Res. 2002 Dec 30;109(1-2):146-60. [12531524 ]
  22. Brunngraber EG, Brown BD, Aro A: Distribution and age-dependent concentration in brain tissue of glycoproteins containing N-acetylgalactosamine. Neurobiology. 1975 Dec;5(6):339-46. [1207868 ]
  23. Maury CP: Carbohydrate patterns of endoscopic mucosal biopsies in cancer of the stomach and chronic gastritis. Clin Chim Acta. 1982 Dec 9;126(2):155-9. [7151277 ]
  24. Pastuszak I, Drake R, Elbein AD. Kidney N-acetylgalactosamine (GalNAc)-1-phosphate kinase, a new pathway of GalNAc activation. J Biol Chem. 1996 Aug 23;271(34):20776-82.


General function:
Involved in galactosyltransferase activity
Specific function:
Transfers N-acetylgalactosamine onto globotriaosylceramide.
Gene Name:
Uniprot ID:
Molecular weight:
General function:
Involved in galactokinase activity
Specific function:
Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates.
Gene Name:
Uniprot ID:
Molecular weight:
General function:
Involved in catalytic activity
Specific function:
Not Available
Gene Name:
Uniprot ID:
Molecular weight:
Not Available
General function:
Involved in UDP-glucuronic acid transmembrane transport
Specific function:
Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis.
Gene Name:
Uniprot ID:
Molecular weight:
General function:
Involved in galactosyltransferase activity
Specific function:
May be involved in keratane sulfate biosynthesis. Transfers N-acetylgalactosamine on to keratan sulfate-related glycans. May play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues
Gene Name:
Uniprot ID:
Molecular weight:
General function:
Involved in transferase activity, transferring glycosyl groups
Specific function:
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
Gene Name:
Uniprot ID:
Molecular weight:
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N'-diacetyllactosediamine formation on gastric mucosa.
Gene Name:
Uniprot ID:
Molecular weight:
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.
Gene Name:
Uniprot ID:
Molecular weight:
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
Involved in the synthesis of the Sd(a) antigen (Sia- alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues. Transfers a beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain
Gene Name:
Uniprot ID:
Molecular weight:
General function:
Involved in catalytic activity
Specific function:
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.
Gene Name:
Uniprot ID:
Molecular weight:
Not Available
General function:
Involved in catalytic activity
Specific function:
Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
Gene Name:
Uniprot ID:
Molecular weight:
Not Available
General function:
Involved in catalytic activity
Specific function:
Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R.
Gene Name:
Uniprot ID:
Molecular weight:
Not Available