Hmp_logo

Human Metabolome Database Version 3.5

HMDB has recently undergone some major changes, if you are experiencing problems please click here to provide us with feedback.

Showing metabocard for Norepinephrine (HMDB00216)

Record Information
Version 3.5
Creation Date 2005-11-16 08:48:42 -0700
Update Date 2013-02-08 17:08:06 -0700
HMDB ID HMDB00216
Secondary Accession Numbers None
Metabolite Identification
Common Name Norepinephrine
Description Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Structure Thumb
Download: MOL | SDF | SMILES | InChI
Display: 2D Structure | 3D Structure
Synonyms
  1. (-)-(R)-Norepinephrine
  2. (-)-alpha-(Aminomethyl)protocatechuyl alcohol
  3. (-)-Arterenol
  4. (-)-Noradrenaline
  5. (-)-Norepinephrine
  6. (R)-(-)-Norepinephrine
  7. (R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol
  8. (R)-Noradrenaline
  9. (R)-Norepinephrine
  10. 4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol
  11. 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
  12. Adrenor
  13. Aktamin
  14. Arterenol
  15. L-2-Amino-1-(3,4-dihydroxyphenyl)ethanol
  16. L-3,4-Dihydroxyphenylethanolamine
  17. L-alpha-(Aminomethyl)-3,4-dihydroxybenzyl alcohol
  18. L-Arterenol
  19. L-Noradrenaline
  20. L-Norepinephrine
  21. Levarterenol
  22. Levoarterenol
  23. Levonor
  24. Levonoradrenaline
  25. Levonorepinephrine
  26. Levophed
  27. Nor-Epirenan
  28. Noradrenalin
  29. Noradrenaline
  30. Norartrinal
  31. Norepirenamine
  32. Sympathin E
Chemical Formula C8H11NO3
Average Molecular Weight 169.1778
Monoisotopic Molecular Weight 169.073893223
IUPAC Name 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
Traditional IUPAC Name norepinephrine
CAS Registry Number 51-41-2
SMILES NC[C@H](O)C1=CC(O)=C(O)C=C1
InChI Identifier InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
InChI Key SFLSHLFXELFNJZ-QMMMGPOBSA-N
Chemical Taxonomy
Kingdom Organic Compounds
Super Class Aromatic Homomonocyclic Compounds
Class Phenols and Derivatives
Sub Class Benzenediols
Other Descriptors
  • Adrenalines(KEGG)
  • Aromatic Homomonocyclic Compounds
  • Biogenic amines(KEGG)
  • noradrenaline(ChEBI)
Substituents
  • 1,2 Aminoalcohol
  • 1,2 Diphenol
  • Benzyl Alcohol Derivative
  • Phenethylamine
  • Primary Aliphatic Amine (Alkylamine)
  • Secondary Alcohol
Direct Parent Catecholamines and Derivatives
Ontology
Status Detected and Quantified
Origin
  • Endogenous
Biofunction
  • Component of Tyrosine metabolism
Application Not Available
Cellular locations
  • Extracellular
Physical Properties
State Solid
Experimental Properties
Property Value Reference
Melting Point 145.2 - 146.4 °C Not Available
Boiling Point Not Available Not Available
Water Solubility 849 mg/mL Not Available
LogP -1.24 HANSCH,C ET AL. (1995)
Predicted Properties
Property Value Source
Water Solubility 12.5 g/L ALOGPS
LogP -1.40 ALOGPS
LogP -0.68 ChemAxon
LogS -1.13 ALOGPS
pKa (strongest acidic) 9.5 ChemAxon
pKa (strongest basic) 8.85 ChemAxon
Hydrogen Acceptor Count 4 ChemAxon
Hydrogen Donor Count 4 ChemAxon
Polar Surface Area 86.71 A2 ChemAxon
Rotatable Bond Count 2 ChemAxon
Refractivity 44.46 ChemAxon
Polarizability 16.96 ChemAxon
Formal Charge 0 ChemAxon
Physiological Charge 1 ChemAxon
Spectra
13C NMR Spectrum
1H NMR Spectrum
MS/MS Spectrum Quattro_QQQ 10
MS/MS Spectrum Quattro_QQQ 25
MS/MS Spectrum Quattro_QQQ 40
MS/MS Spectrum EI-B (HITACHI M-80)
MS/MS Spectrum LC-ESI-QQ (API3000, Applied Biosystems) 10
MS/MS Spectrum LC-ESI-QQ (API3000, Applied Biosystems) 20
MS/MS Spectrum LC-ESI-QQ (API3000, Applied Biosystems) 30
MS/MS Spectrum LC-ESI-QQ (API3000, Applied Biosystems) 40
MS/MS Spectrum LC-ESI-QQ (API3000, Applied Biosystems) 50
MS/MS Spectrum GC-MS
[1H,13C] 2D NMR Spectrum
Biological Properties
Cellular Locations
  • Extracellular
Biofluid Locations
  • Blood
  • Cerebrospinal Fluid (CSF)
  • Urine
Tissue Location
  • Muscle
  • Skeletal Muscle
  • Bladder
  • Fibroblasts
  • Intestine
  • Lymphocyte
  • Neuron
  • Pancreas
  • Placenta
  • Kidney
  • Epidermis
  • Brain
  • Prostate
  • Adrenal Gland
  • Adipose Tissue
  • Adrenal Cortex
  • Adrenal Medulla
  • Nerve Cells
  • Platelet
  • Gonads
  • Heart
  • Central Nervous System
Pathways
Name SMPDB Link KEGG Link
Catecholamine Biosynthesis SMP00012 map00350 Link_out
Tyrosine Metabolism SMP00006 map00350 Link_out
Normal Concentrations
Biofluid Status Value Age Sex Condition Comments
Blood Detected and Quantified
Article_icon
0.0070 (0.0034-0.011) uM Adult (>18 years old) Both Normal Exercise
Blood Detected and Quantified
Article_icon
0.0016 +/- 0.00012 uM Adult (>18 years old) Both Normal Not Available
Blood Detected and Quantified
Article_icon
0.00165 +/- 0.001 uM Adult (>18 years old) Both Normal Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.00112 +/- 6.506e-05 uM Not Specified Not Specified Normal Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.0001 +/- 0.00002 uM Adult (>18 years old) Male Normal Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.0014 uM Adult (>18 years old) Both Normal Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.02 (0.0096-0.031) uM Adult (>18 years old) Both Normal Not Available
Urine Detected and Quantified
Article_icon
0.047 +/- 0.0050 umol/mmol creatinine Adult (>18 years old) Both Normal Not Available
Urine Detected and Quantified
Article_icon
0.0185 (0.00342-0.0336) umol/mmol creatinine Adult (>18 years old) Both Normal Not Available
Urine Detected and Quantified
Article_icon
0.0138 (0.0062-0.032) umol/mmol creatinine Adult (>18 years old) Both Normal Not Available
Abnormal Concentrations
Biofluid Status Value Age Sex Condition Comments
Blood Detected and Quantified
Article_icon
0.001 +/- 0.0013 uM Adult (>18 years old) Both Heat stress Not Available
Blood Detected and Quantified
Article_icon
0.004 +/- 0.022 uM Adult (>18 years old) Both Pheochromocytoma Not Available
Blood Detected and Quantified
Article_icon
0.0037 +/- 0.00048 uM Adult (>18 years old) Both Subarachnoid haemorrhage Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.00005 (0.00003-0.00007) uM Adult (>18 years old) Both Hypothyroidism Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.00141 +/- 8.872e-05 uM Adult (>18 years old) Not Specified borderline hypertensives Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.000757 +/- 0.000266 uM Adult (>18 years old) Not Specified Cerebral infarction, headache, paresthesia and ununconfirmed suspicion of leucemic infaction or brain metastasis with normal CSF value Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.00101 uM Adult (>18 years old) Not Specified Cerebral infarction, headache, paresthesia and ununconfirmed suspicion of leucemic infaction or brain metastasis with normal CSF value but renal insufficiency Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.00108 uM Adult (>18 years old) Not Specified Haemorrhagic infraction Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.00432 uM Adult (>18 years old) Not Specified Bacterial meningitis Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.00214 uM Adult (>18 years old) Not Specified Leucemic meningiosa Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.000745 uM Adult (>18 years old) Not Specified Encephalitis Not Available
Cerebrospinal Fluid (CSF) Detected and Quantified
Article_icon
0.0001 +/- 0.00002 uM Adult (>18 years old) Both Hypothyroidism Not Available
Urine Detected and Quantified
Article_icon
0.084 +/- 0.0068 umol/mmol creatinine Adult (>18 years old) Both Exercise Not Available
Associated Disorders and Diseases
Disease References
Hypothyroidism
  • Sjoberg S, Eriksson M, Nordin C: L-thyroxine treatment and neurotransmitter levels in the cerebrospinal fluid of hypothyroid patients: a pilot study. Eur J Endocrinol. 1998 Nov;139(5):493-7. Pubmed: 9849813 Link_out
    Subarachnoid hemorrhage
    • Lambert G, Naredi S, Eden E, Rydenhag B, Friberg P: Monoamine metabolism and sympathetic nervous activation following subarachnoid haemorrhage: influence of gender and hydrocephalus. Brain Res Bull. 2002 May;58(1):77-82. Pubmed: 12121816 Link_out
      Heat stress
      • McMorris T, Swain J, Smith M, Corbett J, Delves S, Sale C, Harris RC, Potter J: Heat stress, plasma concentrations of adrenaline, noradrenaline, 5-hydroxytryptamine and cortisol, mood state and cognitive performance. Int J Psychophysiol. 2006 Aug;61(2):204-15. Epub 2005 Nov 23. Pubmed: 16309771 Link_out
        Pheochromocytoma
        • Eisenhofer G, Keiser H, Friberg P, Mezey E, Huynh TT, Hiremagalur B, Ellingson T, Duddempudi S, Eijsbouts A, Lenders JW: Plasma metanephrines are markers of pheochromocytoma produced by catechol-O-methyltransferase within tumors. J Clin Endocrinol Metab. 1998 Jun;83(6):2175-85. Pubmed: 9626157 Link_out
          Associated OMIM IDs
          DrugBank ID DB00368 Link_out
          Phenol Explorer Compound ID Not Available
          Phenol Explorer Metabolite ID Not Available
          FoodDB ID FDB000895
          KNApSAcK ID C00001424 Link_out
          Chemspider ID 388394 Link_out
          KEGG Compound ID C00547 Link_out
          BioCyc ID NOREPINEPHRINE Link_out
          BiGG ID 35313 Link_out
          Wikipedia Link Norepinephrine Link_out
          NuGOwiki Link HMDB00216 Link_out
          Metagene Link HMDB00216 Link_out
          METLIN ID 5226 Link_out
          PubChem Compound 439260 Link_out
          PDB ID LNR Link_out
          ChEBI ID 18357 Link_out
          References
          Synthesis Reference Goodall, McC.; Kirshner, Norman. Biosynthesis of adrenaline and norepinephrine by sympathetic nerves and ganglia. Circulation (1958), 17 366-71.
          Material Safety Data Sheet (MSDS) Not Available
          General References
          1. Ahlskog JE, Uitti RJ, Tyce GM, O'Brien JF, Petersen RC, Kokmen E: Plasma catechols and monoamine oxidase metabolites in untreated Parkinson's and Alzheimer's diseases. J Neurol Sci. 1996 Mar;136(1-2):162-8. Pubmed: 8815165 Link_out
          2. Rajda C, Bencsik K, Fuvesi J, Seres E, Vecsei L, Bergquist J: The norepinephrine level is decreased in the lymphocytes of long-term interferon-beta-treated multiple sclerosis patients. Mult Scler. 2006 Jun;12(3):265-70. Pubmed: 16764338 Link_out
          3. Sjoberg S, Eriksson M, Nordin C: L-thyroxine treatment and neurotransmitter levels in the cerebrospinal fluid of hypothyroid patients: a pilot study. Eur J Endocrinol. 1998 Nov;139(5):493-7. Pubmed: 9849813 Link_out
          4. Panholzer TJ, Beyer J, Lichtwald K: Coupled-column liquid chromatographic analysis of catecholamines, serotonin, and metabolites in human urine. Clin Chem. 1999 Feb;45(2):262-8. Pubmed: 9931050 Link_out
          5. Eklundh T, Eriksson M, Sjoberg S, Nordin C: Monoamine precursors, transmitters and metabolites in cerebrospinal fluid: a prospective study in healthy male subjects. J Psychiatr Res. 1996 May-Jun;30(3):201-8. Pubmed: 8884658 Link_out
          6. Takahashi S, Gjessing LR: A fluorometric method combined with thin layer chromatography for the determination of norepinephrine, epinephrine and dopamine in human urine. Clin Chim Acta. 1972 Feb;36(2):369-78. Pubmed: 5008799 Link_out
          7. Ross HA, van Gurp PJ, Willemsen JJ, Lenders JW, Tack CJ, Sweep FC: Transport within the interstitial space, rather than membrane permeability, determines norepinephrine recovery in microdialysis. J Pharmacol Exp Ther. 2006 Nov;319(2):840-6. Epub 2006 Aug 10. Pubmed: 16902052 Link_out
          8. Martinsons A, Rudzite V, Bratslavska O, Saulite V: The influence of kynurenine, neopterin, and norepinephrine on tubular epithelial cells and alveolar fibroblasts. Adv Exp Med Biol. 1999;467:347-52. Pubmed: 10721076 Link_out
          9. Lake CR, Sternberg DE, van Kammen DP, Ballenger JC, Ziegler MG, Post RM, Kopin IJ, Bunney WE: Schizophrenia: elevated cerebrospinal fluid norepinephrine. Science. 1980 Jan 18;207(4428):331-3. Pubmed: 7350667 Link_out
          10. Kaya M, Moriwaki Y, Ka T, Inokuchi T, Yamamoto A, Takahashi S, Tsutsumi Z, Tsuzita J, Oku Y, Yamamoto T: Plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine) and oxypurinol after rigorous exercise. Metabolism. 2006 Jan;55(1):103-7. Pubmed: 16324927 Link_out
          11. Eisenhofer G, Keiser H, Friberg P, Mezey E, Huynh TT, Hiremagalur B, Ellingson T, Duddempudi S, Eijsbouts A, Lenders JW: Plasma metanephrines are markers of pheochromocytoma produced by catechol-O-methyltransferase within tumors. J Clin Endocrinol Metab. 1998 Jun;83(6):2175-85. Pubmed: 9626157 Link_out
          12. Fernqvist E, Linde B: Potent mental stress and insulin absorption in normal subjects. Diabetes Care. 1988 Sep;11(8):650-5. Pubmed: 3065003 Link_out
          13. Pasternak K, Dabrowski W, Wyciszczok T, Korycinska A, Dobija J, Biernacka J, Rzecki Z: The relationship between magnesium, epinephrine and norepinephrine blood concentrations during CABG with normovolemic hemodilution. Magnes Res. 2005 Dec;18(4):245-52. Pubmed: 16548139 Link_out
          14. Engelborghs S, Marescau B, De Deyn PP: Amino acids and biogenic amines in cerebrospinal fluid of patients with Parkinson's disease. Neurochem Res. 2003 Aug;28(8):1145-50. Pubmed: 12834252 Link_out
          15. Albanese J, Leone M, Garnier F, Bourgoin A, Antonini F, Martin C: Renal effects of norepinephrine in septic and nonseptic patients. Chest. 2004 Aug;126(2):534-9. Pubmed: 15302741 Link_out
          16. Shibahara J, Goto A, Niki T, Tanaka M, Nakajima J, Fukayama M: Primary pulmonary paraganglioma: report of a functioning case with immunohistochemical and ultrastructural study. Am J Surg Pathol. 2004 Jun;28(6):825-9. Pubmed: 15166677 Link_out
          17. Wanner A, Horvath G, Brieva JL, Kumar SD, Mendes ES: Nongenomic actions of glucocorticosteroids on the airway vasculature in asthma. Proc Am Thorac Soc. 2004;1(3):235-8. Pubmed: 16113440 Link_out
          18. Raw I, Schmidt BJ, Merzel J: Catecholamines and congenital pain insensitivity. Braz J Med Biol Res. 1984;17(3-4):271-9. Pubmed: 6085021 Link_out
          19. Zhu Y, Zhang W, Chen M, Liu N, Guo J: [Study on expression of norepinephrine and dopamine placental tissues of normal pregnancy and pregnancy induced hypertension syndrome] Zhonghua Fu Chan Ke Za Zhi. 2002 Mar;37(3):142-5. Pubmed: 11953080 Link_out
          Enzymes
          Name: Amine oxidase [flavin-containing] B
          Reactions:
          • RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2 [RN:R01853]
          Gene Name: MAOB
          Uniprot ID: P27338 Link_out
          Protein Sequence: FASTA
          Gene Sequence: FASTA
          Name: Amine oxidase [flavin-containing] A
          Reactions:
          • RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2 [RN:R01853]
          Gene Name: MAOA
          Uniprot ID: P21397 Link_out
          Protein Sequence: FASTA
          Gene Sequence: FASTA
          Name: Dopamine beta-hydroxylase
          Reactions:
          • 3,4-dihydroxyphenethylamine + ascorbate + O2 = noradrenaline + dehydroascorbate + H2O [RN:R02535]
          Gene Name: DBH
          Uniprot ID: P09172 Link_out
          Protein Sequence: FASTA
          Gene Sequence: FASTA
          Name: Catechol O-methyltransferase
          Reactions:
          • S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol [RN:R07330]
          Gene Name: COMT
          Uniprot ID: P21964 Link_out
          Protein Sequence: FASTA
          Gene Sequence: FASTA
          Name: Phenylalanine-4-hydroxylase
          Reactions:
          • L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4a-hydroxytetrahydrobiopterin [RN:R07211]
          Gene Name: PAH
          Uniprot ID: P00439 Link_out
          Protein Sequence: FASTA
          Gene Sequence: FASTA
          Name: Phenylethanolamine N-methyltransferase
          Reactions:
          • S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine [RN:R04033]
          Gene Name: PNMT
          Uniprot ID: P11086 Link_out
          Protein Sequence: FASTA
          Gene Sequence: FASTA
          Name: Glycerol kinase
          Reactions:
          • ATP + glycerol = ADP + sn-glycerol 3-phosphate [RN:R00847]
          Gene Name: GK
          Uniprot ID: P32189 Link_out
          Protein Sequence: FASTA
          Gene Sequence: FASTA
          Name: Cytochrome P450 1A2
          Reactions:
          • RH + reduced flavoprotein + O2 = ROH + oxidized flavoprotein + H2O [RN:R04122]
          Gene Name: CYP1A2
          Uniprot ID: P05177 Link_out
          Protein Sequence: FASTA
          Gene Sequence: FASTA
          Name: Alpha-2A adrenergic receptor
          Reactions:
            Gene Name: ADRA2A
            Uniprot ID: P08913 Link_out
            Protein Sequence: FASTA
            Gene Sequence: FASTA
            Name: Alpha-2B adrenergic receptor
            Reactions:
              Gene Name: ADRA2B
              Uniprot ID: P18089 Link_out
              Protein Sequence: FASTA
              Gene Sequence: FASTA
              Name: Beta-1 adrenergic receptor
              Reactions:
                Gene Name: ADRB1
                Uniprot ID: P08588 Link_out
                Protein Sequence: FASTA
                Gene Sequence: FASTA
                Name: Beta-2 adrenergic receptor
                Reactions:
                  Gene Name: ADRB2
                  Uniprot ID: P07550 Link_out
                  Protein Sequence: FASTA
                  Gene Sequence: FASTA
                  Name: Alpha-1A adrenergic receptor
                  Reactions:
                    Gene Name: ADRA1A
                    Uniprot ID: P35348 Link_out
                    Protein Sequence: FASTA
                    Gene Sequence: FASTA
                    Name: Alpha-1B adrenergic receptor
                    Reactions:
                      Gene Name: ADRA1B
                      Uniprot ID: P35368 Link_out
                      Protein Sequence: FASTA
                      Gene Sequence: FASTA
                      Name: Alpha-1D adrenergic receptor
                      Reactions:
                        Gene Name: ADRA1D
                        Uniprot ID: P25100 Link_out
                        Protein Sequence: FASTA
                        Gene Sequence: FASTA
                        Name: Synaptotagmin-5
                        Reactions:
                          Gene Name: SYT5
                          Uniprot ID: O00445 Link_out
                          Protein Sequence: FASTA
                          Gene Sequence: FASTA
                          Name: Beta-3 adrenergic receptor
                          Reactions:
                            Gene Name: ADRB3
                            Uniprot ID: P13945 Link_out
                            Protein Sequence: FASTA
                            Gene Sequence: FASTA
                            Name: Norepinephrine transporter isoform 2
                            Reactions:
                              Gene Name: Not Available
                              Uniprot ID: Q9Y6W9 Link_out
                              Protein Sequence: FASTA
                              Gene Sequence: FASTA
                              Name: Alpha-2C adrenergic receptor
                              Reactions:
                                Gene Name: ADRA2C
                                Uniprot ID: P18825 Link_out
                                Protein Sequence: FASTA
                                Gene Sequence: FASTA
                                Name: Norepinephrine transporter isoform 1
                                Reactions:
                                  Gene Name: Not Available
                                  Uniprot ID: Q9UQ04 Link_out
                                  Protein Sequence: FASTA
                                  Gene Sequence: FASTA
                                  Name: Norepinephrine transporter
                                  Reactions:
                                    Gene Name: NET
                                    Uniprot ID: Q71UR5 Link_out
                                    Protein Sequence: FASTA
                                    Gene Sequence: FASTA
                                    Transporters
                                    Name: Solute carrier family 22 member 5
                                    Reactions:
                                    • --- []
                                    Gene Name: SLC22A5
                                    Uniprot ID: O76082 Link_out
                                    Protein Sequence: FASTA
                                    Gene Sequence: FASTA
                                    Name: Sodium-dependent noradrenaline transporter
                                    Reactions:
                                    • --- []
                                    Gene Name: SLC6A2
                                    Uniprot ID: P23975 Link_out
                                    Protein Sequence: FASTA
                                    Gene Sequence: FASTA
                                    Name: Solute carrier family 22 member 1
                                    Reactions:
                                    • --- []
                                    Gene Name: SLC22A1
                                    Uniprot ID: O15245 Link_out
                                    Protein Sequence: FASTA
                                    Gene Sequence: FASTA
                                    Name: Solute carrier family 22 member 2
                                    Reactions:
                                      Gene Name: SLC22A2
                                      Uniprot ID: O15244 Link_out
                                      Protein Sequence: FASTA
                                      Gene Sequence: FASTA
                                      Name: Solute carrier family 22 member 3
                                      Reactions:
                                        Gene Name: SLC22A3
                                        Uniprot ID: O75751 Link_out
                                        Protein Sequence: FASTA
                                        Gene Sequence: FASTA