Record Information
Version3.6
Creation Date2005-11-16 15:48:42 UTC
Update Date2013-05-29 19:25:11 UTC
HMDB IDHMDB00234
Secondary Accession NumbersNone
Metabolite Identification
Common NameTestosterone
DescriptionTestosterone is the most important androgen in potency and quantity. Testosterone is synthesized and released by the Leydig cells that lie between the tubules and comprise less than 5% of the total testicular volume. testosterone diffuses into the seminiferous tubules where it is essential for maintaining spermatogenesis. Some binds to an androgen-binding protein (ABP) that is produced by the Sertoli cells and is homologous to the sex-hormone binding globulin that transports testosterone in the general circulation. The ABP carries testosterone in the testicular fluid where it maintains the activity of the accessory sex glands and may also help to retain testosterone within the tubule and bind excess free hormone. Some testosterone is converted to estradiol by Sertoli cell-derived aromatase enzyme. Leydig cell steroidogenesis is controlled primarily by luteinizing hormone with negative feedback of testosterone on the hypothalamic-pituitary axis. The requirement of spermatogenesis for high local concentrations of testosterone means that loss of androgen production is likely to be accompanied by loss of spermatogenesis. Indeed, if testicular androgen production is inhibited by the administration of exogenous androgens then spermatogenesis ceases. This is the basis of using exogenous testosterone as a male contraceptive. testosterone is converted to dihydrotestosterone by 5a-reductase type 2 (EC 1.3.1.22, SRD5A2), the androgen with the highest affinity for the androgen receptor. SRD5A2 deficiency illustrates the importance of dihydrotestosterone for external virilization, as individuals with this condition have normal male internal structures but their external genitalia are of female appearance. There is now clear evidence that the human fetal testis and also the fetal adrenal gland is capable of testosterone biosynthesis during the first trimester. Regardless of the source of androgen production, the target tissue responds by male sexual differentiation of the external genitalia by the end of the first trimester. It is clear that testicular damage may result in loss of testosterone production or the loss of spermatogenesis or both. Loss of androgen production results in hypogonadism, the symptoms of which reflect the functions of testosterone. Male hypogonadism is defined as failure of the testes to produce normal amounts of testosterone, combined with signs and symptoms of androgen deficiency. Systemic testosterone levels fall by about 1% each year in men. Therefore, with increasing longevity and the aging of the population, the number of older men with testosterone deficiency will increase substantially over the next several decades. Serum testosterone levels decrease progressively in aging men, but the rate and magnitude of decrease vary considerably. Approximately 1% of healthy young men have total serum testosterone levels below normal; in contrast, approximately 20% of healthy men over age 60 years have serum testosterone levels below normal. (PMID: 17904450 , 17875487 ).
Structure
Thumb
Synonyms
  1. (+)-testosterone
  2. (+-)-8-iso-testosterone
  3. (+-)-retrotestosterone
  4. (+-)-testosterone
  5. (17b)-17-hydroxy-androst-4-en-3-one
  6. 13-Iso-testosterone
  7. 17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
  8. 17-Hydroxy-androst-4-en-3-one
  9. 17-Hydroxy-D4-androsten-3-one
  10. 17a-Hydroxy-(13a)-androst-4-en-3-one
  11. 17a-Hydroxy-13a-androst-4-en-3-one
  12. 17a-Hydroxy-14b-androst-4-en-3-one
  13. 17a-Hydroxy-androst-4-en-3-one
  14. 17b-Hydroxy-(10a)-androst-4-en-3-one
  15. 17b-Hydroxy-(13a)-androst-4-en-3-one
  16. 17b-Hydroxy-(8a)-androst-4-en-3-one
  17. 17b-Hydroxy-(8a,10a)-androst-4-en-3-one
  18. 17b-Hydroxy-(9b)-androst-4-en-3-one
  19. 17b-Hydroxy-(9b,10a)-androst-4-en-3-one
  20. 17b-Hydroxy-13a-androst-4-en-3-one
  21. 17b-Hydroxy-8a-androst-4-en-3-one
  22. 17b-Hydroxy-androst-4-en-3-on
  23. 17b-Hydroxy-androst-4-en-3-one
  24. 17b-Hydroxy-D4-androsten-3-one
  25. 17b-Hydroxyandrost-4-en-3-one
  26. 17b-Hydroxyandrost-4-ene-3-one
  27. 17b-Testosterone
  28. 4-Androsten-3-one-17b-ol
  29. 8-Iso-testosterone
  30. 9b,10a-Testosterone
  31. 9b-Testosterone
  32. Androderm
  33. AndroGel
  34. Androlin
  35. Andronaq
  36. Andropatch
  37. Androst-4-en-17b-ol-3-one
  38. Androst-4-ene-17b-ol-3-one
  39. Andrusol
  40. Cristerona T
  41. D4-Androsten-17b-ol-3-one
  42. Epitestosteron
  43. Geno-cristaux Gremy
  44. Homosteron
  45. Homosterone
  46. Lumitestosteron
  47. Mertestate
  48. Neotestis
  49. Oreton
  50. Orquisteron
  51. Perandren
  52. Percutacrine androgenique
  53. Primotest
  54. Primoteston
  55. Rac-17b-hydroxy-(13a)androst-4-en-3-one
  56. Rac-17b-hydroxy-(8a)-androst-4-en-3-one
  57. Rac-17b-hydroxy-(9b,10a)androst-4-en-3-one
  58. Rac-17b-hydroxy-androst-4-en-3-one
  59. Relibra
  60. Retrotestosterone
  61. Sustanon
  62. Sustanone
  63. Sustason 250
  64. Synandrol F
  65. Teslen
  66. Testandrone
  67. Testiculosterone
  68. Testim
  69. Testobase
  70. Testoderm
  71. Testogel
  72. Testolent
  73. Testolin
  74. Testopropon
  75. Testosteroid
  76. Testosteron
  77. Testoviron Schering
  78. Testoviron T
  79. Testro AQ
  80. Testrone
  81. Testryl
  82. Tostrelle
  83. Tostrex
  84. Viatrel
  85. Virormone
  86. Virosterone
Chemical FormulaC19H28O2
Average Molecular Weight288.4244
Monoisotopic Molecular Weight288.20893014
IUPAC Name(1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
Traditional IUPAC Nametestosterone
CAS Registry Number58-22-0
SMILES
[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
InChI Identifier
InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1
InChI KeyMUMGGOZAMZWBJJ-DYKIIFRCSA-N
Chemical Taxonomy
KingdomOrganic Compounds
Super ClassLipids
ClassSteroids and Steroid Derivatives
Sub ClassAndrogens and Derivatives
Other Descriptors
  • Aliphatic Homopolycyclic Compounds
  • Hydroxysteroids
  • Ketosteroids
  • a hormone(Cyc)
Substituents
  • Cyclic Alcohol
  • Cyclohexane
  • Cyclohexene
  • Decaline
  • Ketone
  • Secondary Alcohol
  • Sesquiterpene Backbone
Direct ParentAndrogens and Derivatives
Ontology
StatusDetected and Quantified
Origin
  • Endogenous
  • Food
Biofunction
  • Cell signaling
  • Fuel and energy storage
  • Fuel or energy source
  • Hormones, Membrane component
  • Membrane integrity/stability
Application
  • Nutrients
  • Stabilizers
  • Surfactants and Emulsifiers
Cellular locations
  • Cytoplasm
  • Extracellular
  • Membrane (predicted from logP)
  • Endoplasmic reticulum
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting Point155 °CNot Available
Boiling PointNot AvailableNot Available
Water Solubility0.0234 mg/mLNot Available
LogP3.32HANSCH,C ET AL. (1995)
Predicted Properties
PropertyValueSource
water solubility0.033 g/LALOGPS
logP2.99ALOGPS
logP3.37ChemAxon
logS-3.9ALOGPS
pKa (strongest acidic)19.09ChemAxon
pKa (strongest basic)-0.88ChemAxon
physiological charge0ChemAxon
hydrogen acceptor count2ChemAxon
hydrogen donor count1ChemAxon
polar surface area37.3ChemAxon
rotatable bond count0ChemAxon
refractivity84.43ChemAxon
polarizability33.93ChemAxon
Spectra
Spectra
Biological Properties
Cellular Locations
  • Cytoplasm
  • Extracellular
  • Membrane (predicted from logP)
  • Endoplasmic reticulum
Biofluid Locations
  • Blood
  • Cerebrospinal Fluid (CSF)
  • Saliva
  • Urine
Tissue Location
  • Brain
  • Gonads
  • Hypothalamus
  • Muscle
  • Sperm
  • Testes
Pathways
NameSMPDB LinkKEGG Link
Androgen and Estrogen MetabolismSMP00068map00150
Normal Concentrations
BiofluidStatusValueAgeSexConditionReference
BloodDetected and Quantified0.00125 +/- 0.00042 uMAdult (>18 years old)FemaleNormal
BloodDetected and Quantified0.013 (0.0083-0.0286) uMAdult (>18 years old)MaleNormal
BloodDetected and Quantified0.0094 +/- 0.0014 uMAdult (>18 years old)MaleNormal
Cerebrospinal Fluid (CSF)Detected and Quantified0.00101 (0.00002-0.002) uMAdult (>18 years old)Not SpecifiedNormal
Cerebrospinal Fluid (CSF)Detected and Quantified0.00065 +/- 0.00012 uMAdult (>18 years old)MaleNormal
SalivaDetected and Quantified0.00120 (0.00108-0.00133) uMAdult (>18 years old)MaleNormal
SalivaDetected and Quantified0.000677 (0.000590-0.000764) uMAdult (>18 years old)FemaleNormal
UrineDetected and Quantified0.000121 +/- 0.00002149 umol/mmol creatinineAdult (>18 years old)BothNormal
UrineDetected and Quantified1.07 +/- 0.19 umol/mmol creatinineAdult (>18 years old)BothNormal
Abnormal Concentrations
BiofluidStatusValueAgeSexConditionReference
BloodDetected and Quantified9.31 (3.31-19.95) uMAdult (>18 years old)MaleCadmium exposure
BloodDetected and Quantified0.010 +/- 0.013 uMAdolescent (13-18 years old)MaleHypogonadism
Cerebrospinal Fluid (CSF)Detected and Quantified3.400e-05 +/- 1.665e-05 uMAdult (>18 years old)Not SpecifiedLeuprolide acetate-induce hypogonadism
Cerebrospinal Fluid (CSF)Detected and Quantified0.000497 +/- 0.000222 uMAdult (>18 years old)Not SpecifiedLeuprolide acetate-induced hypogonadism with testosterone replacment
Associated Disorders and Diseases
Disease References
Cadmium exposure
  • Zeng X, Lin T, Zhou Y, Kong Q: Alterations of serum hormone levels in male workers occupationally exposed to cadmium. J Toxicol Environ Health A. 2002 Apr 12;65(7):513-21. Pubmed: 11939709
Hypogonadism
Associated OMIM IDsNone
DrugBank IDDB00624
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDFDB011544
KNApSAcK IDC00003675
Chemspider ID5791
KEGG Compound IDC00535
BioCyc IDNot Available
BiGG ID35280
Wikipedia LinkTestosterone
NuGOwiki LinkHMDB00234
Metagene LinkHMDB00234
METLIN ID390
PubChem Compound6013
PDB IDTES
ChEBI ID17347
References
Synthesis ReferenceErcoli, Alberto; De Ruggieri, Pietro. An improved method of preparing testosterone, dihydrotestosterone, and some of their esters. Journal of the American Chemical Society (1953), 75 650-3.
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Kim YS, Zhang H, Kim HY: Profiling neurosteroids in cerebrospinal fluids and plasma by gas chromatography/electron capture negative chemical ionization mass spectrometry. Anal Biochem. 2000 Jan 15;277(2):187-95. Pubmed: 10625505
  2. Cutolo M, Sulli A, Capellino S, Villaggio B, Montagna P, Pizzorni C, Paolino S, Seriolo B, Felli L, Straub RH: Anti-TNF and sex hormones. Ann N Y Acad Sci. 2006 Jun;1069:391-400. Pubmed: 16855166
  3. Schwarz S, Pohl P: Steroid hormones and steroid hormone binding globulins in cerebrospinal fluid studied in individuals with intact and with disturbed blood-cerebrospinal fluid barrier. Neuroendocrinology. 1992 Feb;55(2):174-82. Pubmed: 1620285
  4. Schaap LA, Pluijm SM, Smit JH, van Schoor NM, Visser M, Gooren LJ, Lips P: The association of sex hormone levels with poor mobility, low muscle strength and incidence of falls among older men and women. Clin Endocrinol (Oxf). 2005 Aug;63(2):152-60. Pubmed: 16060908
  5. Archer JS, Love-Geffen TE, Herbst-Damm KL, Swinney DA, Chang JR: Effect of estradiol versus estradiol and testosterone on brain-activation patterns in postmenopausal women. Menopause. 2006 May-Jun;13(3):528-37. Pubmed: 16735951
  6. Handelsman DJ: Clinical review: The rationale for banning human chorionic gonadotropin and estrogen blockers in sport. J Clin Endocrinol Metab. 2006 May;91(5):1646-53. Epub 2006 Feb 14. Pubmed: 16478815
  7. Duschek EJ, Gooren LJ, Netelenbos C: Comparison of effects of the rise in serum testosterone by raloxifene and oral testosterone on serum insulin-like growth factor-1 and insulin-like growth factor binding protein-3. Maturitas. 2005 Jul 16;51(3):286-93. Pubmed: 15978972
  8. Huang I, Jones J, Khorram O: Human seminal plasma nitric oxide: correlation with sperm morphology and testosterone. Med Sci Monit. 2006 Mar;12(3):CR103-6. Epub 2006 Feb 23. Pubmed: 16501419
  9. Hussein A, Ozgok Y, Ross L, Niederberger C: Clomiphene administration for cases of nonobstructive azoospermia: a multicenter study. J Androl. 2005 Nov-Dec;26(6):787-91; discussion 792-3. Pubmed: 16291975
  10. Ahtiainen JP, Pakarinen A, Alen M, Kraemer WJ, Hakkinen K: Short vs. long rest period between the sets in hypertrophic resistance training: influence on muscle strength, size, and hormonal adaptations in trained men. J Strength Cond Res. 2005 Aug;19(3):572-82. Pubmed: 16095405
  11. Landman AD, Sanford LM, Howland BE, Dawes C, Pritchard ET: Testosterone in human saliva. Experientia. 1976;32(7):940-1. Pubmed: 954994
  12. Knickmeyer RC, Wheelwright S, Taylor K, Raggatt P, Hackett G, Baron-Cohen S: Gender-typed play and amniotic testosterone. Dev Psychol. 2005 May;41(3):517-28. Pubmed: 15910159
  13. Fejes I, Koloszar S, Szollosi J, Zavaczki Z, Pal A: Is semen quality affected by male body fat distribution? Andrologia. 2005 Oct;37(5):155-9. Pubmed: 16266392
  14. Jarow JP, Zirkin BR: The androgen microenvironment of the human testis and hormonal control of spermatogenesis. Ann N Y Acad Sci. 2005 Dec;1061:208-20. Pubmed: 16467270
  15. Rovensky J, Radikova Z, Imrich R, Greguska O, Vigas M, Macho L: Gonadal and adrenal steroid hormones in plasma and synovial fluid of patients with rheumatoid arthritis. Endocr Regul. 2004 Dec;38(4):143-9. Pubmed: 15841793
  16. Klimek M, Pabian W, Tomaszewska B, Kolodziejczyk J: Levels of plasma ACTH in men from infertile couples. Neuro Endocrinol Lett. 2005 Aug;26(4):347-50. Pubmed: 16136011
  17. Shores MM, Matsumoto AM, Sloan KL, Kivlahan DR: Low serum testosterone and mortality in male veterans. Arch Intern Med. 2006 Aug 14-28;166(15):1660-5. Pubmed: 16908801
  18. Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS, Montori VM: Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2006 Jun;91(6):1995-2010. Epub 2006 May 23. Pubmed: 16720669
  19. Jarow JP, Wright WW, Brown TR, Yan X, Zirkin BR: Bioactivity of androgens within the testes and serum of normal men. J Androl. 2005 May-Jun;26(3):343-8. Pubmed: 15867001
  20. Bridger T, MacDonald S, Baltzer F, Rodd C: Randomized placebo-controlled trial of metformin for adolescents with polycystic ovary syndrome. Arch Pediatr Adolesc Med. 2006 Mar;160(3):241-6. Pubmed: 16520442
  21. Kazi M, Geraci SA, Koch CA: Considerations for the diagnosis and treatment of testosterone deficiency in elderly men. Am J Med. 2007 Oct;120(10):835-40. Pubmed: 17904450
  22. Krone N, Hanley NA, Arlt W: Age-specific changes in sex steroid biosynthesis and sex development. Best Pract Res Clin Endocrinol Metab. 2007 Sep;21(3):393-401. Pubmed: 17875487
  23. Contraceptive efficacy of testosterone-induced azoospermia in normal men. World Health Organization Task Force on methods for the regulation of male fertility. Lancet. 1990 Oct 20;336(8721):955-9. Pubmed: 1977002
  24. Hoberman JM, Yesalis CE: The history of synthetic testosterone. Sci Am. 1995 Feb;272(2):76-81. Pubmed: 7817189
  25. Freeman ER, Bloom DA, McGuire EJ: A brief history of testosterone. J Urol. 2001 Feb;165(2):371-3. Pubmed: 11176375

Only showing the first 50 proteins. There are 74 proteins in total.

Enzymes

Gene Name:
MAOA
Uniprot ID:
P21397
Gene Name:
SULT1E1
Uniprot ID:
P49888
Gene Name:
AKR1C3
Uniprot ID:
P42330
Reactions
Testosterone + NAD unknown Androstenedione + NADHdetails
Testosterone + NADP unknown Androstenedione + NADPHdetails
Gene Name:
HSD17B2
Uniprot ID:
P37059
Reactions
Testosterone + NAD unknown Androstenedione + NADHdetails
Testosterone + NAD unknown Androstenedione + NADH + Hydrogen Iondetails
Gene Name:
UGT2B28
Uniprot ID:
Q9BY64
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
HSD17B8
Uniprot ID:
Q92506
Reactions
Testosterone + NAD unknown Androstenedione + NADHdetails
Testosterone + NAD unknown Androstenedione + NADH + Hydrogen Iondetails
Gene Name:
UGT2B4
Uniprot ID:
P06133
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT1A4
Uniprot ID:
P22310
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT2B10
Uniprot ID:
P36537
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT2B7
Uniprot ID:
P16662
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT2B15
Uniprot ID:
P54855
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT2A1
Uniprot ID:
Q9Y4X1
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT1A1
Uniprot ID:
P22309
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT1A9
Uniprot ID:
O60656
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT1A8
Uniprot ID:
Q9HAW9
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT1A3
Uniprot ID:
P35503
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT1A10
Uniprot ID:
Q9HAW8
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT2B17
Uniprot ID:
O75795
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT1A6
Uniprot ID:
P19224
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT1A5
Uniprot ID:
P35504
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT2B11
Uniprot ID:
O75310
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
UGT1A7
Uniprot ID:
Q9HAW7
Reactions
Testosterone + Uridine diphosphate glucuronic acid unknown Testosterone glucuronide + Uridine 5'-diphosphatedetails
Gene Name:
HSD17B11
Uniprot ID:
Q8NBQ5
Gene Name:
AKR1D1
Uniprot ID:
P51857
Reactions
5b-Dihydrotestosterone + NADP unknown Testosterone + NADPH + Hydrogen Iondetails
Gene Name:
SRD5A2
Uniprot ID:
P31213
Reactions
Dihydrotestosterone + Acceptor unknown Testosterone + Reduced acceptordetails
Gene Name:
SRD5A1
Uniprot ID:
P18405
Reactions
Dihydrotestosterone + Acceptor unknown Testosterone + Reduced acceptordetails
Gene Name:
GSTA3
Uniprot ID:
Q16772
Gene Name:
HSD17B3
Uniprot ID:
P37058
Reactions
Testosterone + NADP unknown Androstenedione + NADPHdetails
Testosterone + NADP unknown Androstenedione + NADPH + Hydrogen Iondetails
Gene Name:
CYP3A4
Uniprot ID:
P08684
Gene Name:
CYP2C9
Uniprot ID:
P11712
Gene Name:
CYP2C19
Uniprot ID:
P33261
Gene Name:
CYP2E1
Uniprot ID:
P05181
Gene Name:
CYP3A43
Uniprot ID:
Q9HB55
Gene Name:
CYP1B1
Uniprot ID:
Q16678
Gene Name:
CYP2C18
Uniprot ID:
P33260
Gene Name:
CYP2F1
Uniprot ID:
P24903
Gene Name:
CYP4X1
Uniprot ID:
Q8N118
Gene Name:
CYP2B6
Uniprot ID:
P20813
Gene Name:
CYP3A5
Uniprot ID:
P20815
Gene Name:
CYP1A1
Uniprot ID:
P04798
Gene Name:
CYP2A13
Uniprot ID:
Q16696
Gene Name:
CYP3A7
Uniprot ID:
P24462
Gene Name:
CYP4B1
Uniprot ID:
P13584
Gene Name:
CYP4Z1
Uniprot ID:
Q86W10
Gene Name:
CYP1A2
Uniprot ID:
P05177
Gene Name:
CYP19A1
Uniprot ID:
P11511
Gene Name:
CYP2C8
Uniprot ID:
P10632
Gene Name:
CYP2S1
Uniprot ID:
Q96SQ9
Gene Name:
CYP2J2
Uniprot ID:
P51589

Transporters

Gene Name:
ABCB1
Uniprot ID:
P08183
Gene Name:
SLC22A4
Uniprot ID:
Q9H015
Gene Name:
SLC10A1
Uniprot ID:
Q14973
Gene Name:
SLC22A1
Uniprot ID:
O15245
Gene Name:
SLC22A3
Uniprot ID:
O75751
Gene Name:
SLC22A7
Uniprot ID:
Q9Y694

Only showing the first 50 proteins. There are 74 proteins in total.