Record Information
Version3.6
Creation Date2005-11-16 15:48:42 UTC
Update Date2013-02-09 00:08:09 UTC
HMDB IDHMDB00243
Secondary Accession NumbersNone
Metabolite Identification
Common NamePyruvic acid
DescriptionPyruvic acid is an intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed.) Biological Source: Intermediate in primary metabolism including fermentation processes. Present in muscle in redox equilibrium with Lactic acid. A common constituent, as a chiral cyclic acetal linked to saccharide residues, of bacterial polysaccharides. Isolated from cane sugar fermentation broth and peppermint. Constituent of Bauhinia purpurea, Cicer arietinum (chickpea), Delonix regia, Pisum sativum (pea) and Trigonella caerulea (sweet trefoil) Use/Importance: Reagent for regeneration of carbonyl compdounds from semicarbazones, phenylhydrazones and oximes. Flavoring ingredient (Dictionary of Organic Compounds).
Structure
Thumb
Synonyms
  1. 2-Oxopropanoate
  2. 2-Oxopropanoic acid
  3. 2-Oxopropionate
  4. 2-Oxopropionic acid
  5. a-Ketopropionate
  6. a-Ketopropionic acid
  7. Acetylformate
  8. Acetylformic acid
  9. alpha-Ketopropionate
  10. alpha-Ketopropionic acid
  11. BTS
  12. Pyroracemate
  13. Pyroracemic acid
  14. Pyruvate
Chemical FormulaC3H4O3
Average Molecular Weight88.0621
Monoisotopic Molecular Weight88.016043994
IUPAC Name2-oxopropanoic acid
Traditional IUPAC Namepyruvic acid
CAS Registry Number127-17-3
SMILES
CC(=O)C(O)=O
InChI Identifier
InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
InChI KeyLCTONWCANYUPML-UHFFFAOYSA-N
Chemical Taxonomy
KingdomOrganic Compounds
Super ClassOrganic Acids and Derivatives
ClassKeto-Acids and Derivatives
Sub ClassAlpha Keto-Acids and Derivatives
Other Descriptors
  • 2-oxo monocarboxylic acid(ChEBI)
  • Aliphatic Acyclic Compounds
  • Oxo fatty acids(Lipidmaps)
Substituents
  • Carboxylic Acid
  • Ketone
Direct ParentAlpha Keto-Acids and Derivatives
Ontology
StatusDetected and Quantified
Origin
  • Endogenous
  • Microbial
Biofunction
  • Anti-oxidant
  • Component of Alanine and aspartate metabolism
  • Component of Butanoate metabolism
  • Component of Cysteine metabolism
  • Component of Glutamate metabolism
  • Component of Glycine, serine and threonine metabolism
  • Component of Phenylalanine, tyrosine and tryptophan biosynthesis
  • Component of Propanoate metabolism
  • Component of Purine metabolism
  • Component of Pyruvate metabolism
  • Component of Valine, leucine and isoleucine biosynthesis
  • Energy source
ApplicationNot Available
Cellular locations
  • Extracellular
  • Mitochondria
  • Peroxisome
Physical Properties
StateLiquid
Experimental Properties
PropertyValueReference
Melting Point13.8 °CNot Available
Boiling PointNot AvailableNot Available
Water Solubility1000.0 mg/mLNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
water solubility134 g/LALOGPS
logP-0.38ALOGPS
logP0.066ChemAxon
logS0.18ALOGPS
pKa (strongest acidic)2.93ChemAxon
pKa (strongest basic)-9.6ChemAxon
physiological charge-1ChemAxon
hydrogen acceptor count3ChemAxon
hydrogen donor count1ChemAxon
polar surface area54.37ChemAxon
rotatable bond count1ChemAxon
refractivity17.99ChemAxon
polarizability7.32ChemAxon
Spectra
Spectra
Biological Properties
Cellular Locations
  • Extracellular
  • Mitochondria
  • Peroxisome
Biofluid Locations
  • Blood
  • Cellular Cytoplasm
  • Cerebrospinal Fluid (CSF)
  • Saliva
  • Urine
Tissue Location
  • Adipose Tissue
  • Brain
  • Fibroblasts
  • Kidney
  • Liver
  • Muscle
  • Myocardium
  • Neuron
  • Pancreas
  • Skeletal Muscle
  • Spleen
  • Testes
  • Thyroid Gland
Pathways
NameSMPDB LinkKEGG Link
Alanine MetabolismSMP00055map00250
Amino Sugar MetabolismSMP00045map00520
Ammonia RecyclingSMP00009map00910
Citric Acid CycleSMP00057map00020
Cysteine MetabolismSMP00013map00270
GluconeogenesisSMP00128map00010
Glucose-Alanine CycleSMP00127Not Available
Glycine and Serine MetabolismSMP00004map00260
GlycolysisSMP00040map00010
Pyruvaldehyde DegradationSMP00459Not Available
Pyruvate MetabolismSMP00060map00620
Transfer of Acetyl Groups into MitochondriaSMP00466Not Available
Urea CycleSMP00059map00330
Normal Concentrations
BiofluidStatusValueAgeSexConditionReference
BloodDetected and Quantified34.5 +/- 25.2 uMAdult (>18 years old)Not SpecifiedNormal
BloodDetected and Quantified64 (22-258) uMAdult (>18 years old)BothNormal
BloodDetected and Quantified81.0 +/- 34.0 uMNewborn (0-30 days old)BothNormal
  • Geigy Scient...
BloodDetected and Quantified76.0 +/- 10.0 uMChildren (1-13 year old)BothNormal
  • Geigy Scient...
BloodDetected and Quantified63.0 +/- 25.0 uMAdult (>18 years old)BothNormal
  • Geigy Scient...
BloodDetected and Quantified75.5 (10.0-141.0) uMNewborn (0-30 days old)Not SpecifiedNormal
BloodDetected and Quantified64 (28-145) uMAdult (>18 years old)MaleNormal
BloodDetected and Quantified64 (29-144) uMAdult (>18 years old)FemaleNormal
BloodDetected and Quantified67 (27-164) uMAdult (>18 years old)BothNormal
BloodDetected and Quantified64 (29-144) uMAdult (>18 years old)BothNormal
BloodDetected and Quantified66 (34-117) uMElderly (>65 years old)BothNormal
BloodDetected and Quantified93.5 (27.0-160.0) uMAdult (>18 years old)BothNormal
Cellular CytoplasmDetected and Quantified77.0 (27.0-127) uMAdult (>18 years old)BothNormal
Cellular CytoplasmDetected and Quantified360 (350-370) uMAdult (>18 years old)BothNormal
Cerebrospinal Fluid (CSF)Detected and Quantified153.0 (121.0-185.0) uMAdult (>18 years old)BothNormal
Cerebrospinal Fluid (CSF)Detected and Quantified53 +/- 42 uMNot SpecifiedBothNormal
Cerebrospinal Fluid (CSF)Detected and Quantified71.0 +/- 31.0 uMAdult (>18 years old)Not SpecifiedNormal
Cerebrospinal Fluid (CSF)Detected and Quantified115.0 +/- 17.0 uMAdult (>18 years old)BothNormal
  • Geigy Scient...
Cerebrospinal Fluid (CSF)Detected and Quantified136.0 +/- 29.0 uMChildren (1-13 year old)BothNormal
  • Geigy Scient...
SalivaDetected and Quantified5350 (100-10600) uMAdult (>18 years old)BothNormal
SalivaDetected and Quantified1-128 uMAdult (>18 years old)MaleCommentnormal
SalivaDetected and Quantified1-76 uMAdult (>18 years old)MaleCommentnormal
UrineDetected and Quantified9.79 +/- 9.34 umol/mmol creatinineInfant (0-1 year old)Not SpecifiedNormal
UrineDetected and Quantified2.1 (1.0-3.7) umol/mmol creatinineAdult (>18 years old)BothCommentNormal
UrineDetected and Quantified2.27-79.53 umol/mmol creatinineAdult (>18 years old)BothNormal
  • David F. Put...
UrineDetected but not QuantifiedNot ApplicableAdult (>18 years old)BothNormal
UrineDetected and Quantified4.21 +/- 1.37 umol/mmol creatinineChildren (1-13 year old)BothNormal
  • Geigy Scient...
UrineDetected and Quantified1.7985 (0-3.597) umol/mmol creatinineAdult (>18 years old)BothNormal
UrineDetected and Quantified5.4 (2.6-7.9) umol/mmol creatinineAdult (>18 years old)BothNormal
UrineDetected and Quantified2.7 (0.8-6.4) umol/mmol creatinineAdult (>18 years old)BothCommentNormal
UrineDetected but not QuantifiedNot ApplicableAdult (>18 years old)MaleCommentNormal
UrineDetected but not QuantifiedNot ApplicableAdult (>18 years old)MaleCommentNormal
UrineDetected and Quantified21.2 (8.8-59.3) umol/mmol creatinineNewborn (0-30 days old)BothNormal
UrineDetected and Quantified28.6 (12.9-43.0) umol/mmol creatinineInfant (0-1 year old)BothNormal
UrineDetected and Quantified12.4 (5.3-22.1) umol/mmol creatinineChildren (1-13 year old)BothNormal
UrineDetected and Quantified10.2 (4.7-40.5) umol/mmol creatinineAdolescent (13-18 years old)BothNormal
UrineDetected and Quantified38.50 (18.32 – 69.64) umol/mmol creatinineAdult (>18 years old)BothNormal
  • Lorena Ivona...
UrineDetected and Quantified2.13 (0.54-8.67) umol/mmol creatinineAdult (>18 years old)MaleNormal
UrineDetected and Quantified1.68 (0.62-3.30) umol/mmol creatinineAdult (>18 years old)FemaleNormal
UrineDetected and Quantified7 umol/mmol creatinineAdult (>18 years old)BothNormal
Abnormal Concentrations
BiofluidStatusValueAgeSexConditionReference
BloodDetected and Quantified50.2 +/- 40 uMAdult (>18 years old)Not SpecifiedHeart Transplant
Cellular CytoplasmDetected and Quantified140 (130-150) uMAdult (>18 years old)BothAnoxia
Cerebrospinal Fluid (CSF)Detected and Quantified195.0 (175.0-215.0) uMAdult (>18 years old)BothCommentMeningitis
UrineDetected and Quantified0.2 (0.10-0.30) umol/mmol creatinineChildren (1-13 year old)Both3-Methylglutaconic Aciduria (TYPE II), X-LINKED
UrineDetected and Quantified45.58 (18.06 – 104.62) umol/mmol creatinineAdult (>18 years old)BothType 1 diabetes Mellitus
  • Lorena Ivona...
Associated Disorders and Diseases
Disease References
Anoxia
  • Zupke C, Sinskey AJ, Stephanopoulos G: Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas. Appl Microbiol Biotechnol. 1995 Dec;44(1-2):27-36. Pubmed: 8579834
Meningitis
  • Subramanian A, Gupta A, Saxena S, Gupta A, Kumar R, Nigam A, Kumar R, Mandal SK, Roy R: Proton MR CSF analysis and a new software as predictors for the differentiation of meningitis in children. NMR Biomed. 2005 Jun;18(4):213-25. Pubmed: 15627241
3-methylglutaconic aciduria type II, X-linked
Associated OMIM IDs
    302060 (3-methylglutaconic aciduria type II, X-linked)
DrugBank IDDB00119
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDFDB008293
KNApSAcK IDC00001200
Chemspider ID1031
KEGG Compound IDC00022
BioCyc IDPYRUVATE
BiGG ID33546
Wikipedia LinkPyruvic acid
NuGOwiki LinkHMDB00243
Metagene LinkHMDB00243
METLIN ID117
PubChem Compound1060
PDB IDPYR
ChEBI ID32816
References
Synthesis ReferenceXiang, Wei; Okita, Motomu. Preparation of pyruvic acid. Jpn. Kokai Tokkyo Koho (2003), 5 pp.
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Tsuchiya H, Hashizume I, Tokunaga T, Tatsumi M, Takagi N, Hayashi T: High-performance liquid chromatography of alpha-keto acids in human saliva. Arch Oral Biol. 1983;28(11):989-92. Pubmed: 6581765
  2. Guneral F, Bachmann C: Age-related reference values for urinary organic acids in a healthy Turkish pediatric population. Clin Chem. 1994 Jun;40(6):862-6. Pubmed: 8087979
  3. Hoffmann GF, Meier-Augenstein W, Stockler S, Surtees R, Rating D, Nyhan WL: Physiology and pathophysiology of organic acids in cerebrospinal fluid. J Inherit Metab Dis. 1993;16(4):648-69. Pubmed: 8412012
  4. Silwood CJ, Lynch E, Claxson AW, Grootveld MC: 1H and (13)C NMR spectroscopic analysis of human saliva. J Dent Res. 2002 Jun;81(6):422-7. Pubmed: 12097436
  5. Subramanian A, Gupta A, Saxena S, Gupta A, Kumar R, Nigam A, Kumar R, Mandal SK, Roy R: Proton MR CSF analysis and a new software as predictors for the differentiation of meningitis in children. NMR Biomed. 2005 Jun;18(4):213-25. Pubmed: 15627241
  6. Nakayama Y, Kinoshita A, Tomita M: Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition. Theor Biol Med Model. 2005 May 9;2(1):18. Pubmed: 15882454
  7. Zupke C, Sinskey AJ, Stephanopoulos G: Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas. Appl Microbiol Biotechnol. 1995 Dec;44(1-2):27-36. Pubmed: 8579834
  8. Foster KJ, Alberti KG, Hinks L, Lloyd B, Postle A, Smythe P, Turnell DC, Walton R: Blood intermediary metabolite and insulin concentrations after an overnight fast: reference ranges for adults, and interrelations. Clin Chem. 1978 Sep;24(9):1568-72. Pubmed: 688619
  9. Nielsen J, Ytrebo LM, Borud O: Lactate and pyruvate concentrations in capillary blood from newborns. Acta Paediatr. 1994 Sep;83(9):920-2. Pubmed: 7819686
  10. Ka T, Yamamoto T, Moriwaki Y, Kaya M, Tsujita J, Takahashi S, Tsutsumi Z, Fukuchi M, Hada T: Effect of exercise and beer on the plasma concentration and urinary excretion of purine bases. J Rheumatol. 2003 May;30(5):1036-42. Pubmed: 12734903
  11. Talseth T, Haegele KD, McNay JL, Skrdlant HB, Clementi WA, Shepherd AM: Pharmacokinetics and cardiovascular effects in rabbits of a major hydralazine metabolite, the hydralazine pyruvic-acid hydrazone. J Pharmacol Exp Ther. 1979 Dec;211(3):509-13. Pubmed: 512915
  12. Reece PA, Cozamanis I, Zacest R: Selective high-performance liquid chromatographic assays for hydralazine and its metabolites in plasma of man. J Chromatogr. 1980 Mar 14;181(3-4):427-40. Pubmed: 7391156
  13. Meijer-Severs GJ, Van Santen E, Meijer BC: Short-chain fatty acid and organic acid concentrations in feces of healthy human volunteers and their correlations with anaerobe cultural counts during systemic ceftriaxone administration. Scand J Gastroenterol. 1990 Jul;25(7):698-704. Pubmed: 2396083
  14. Elling D, Bader K: [Biochemical changes in cervix mucus in stepwise malignant transformation of cervix epithelium] Zentralbl Gynakol. 1990;112(9):555-60. Pubmed: 2378186
  15. Mongan PD, Capacchione J, West S, Karaian J, Dubois D, Keneally R, Sharma P: Pyruvate improves redox status and decreases indicators of hepatic apoptosis during hemorrhagic shock in swine. Am J Physiol Heart Circ Physiol. 2002 Oct;283(4):H1634-44. Epub 2002 Jun 20. Pubmed: 12234818

Only showing the first 50 proteins. There are 59 proteins in total.

Enzymes

Gene Name:
PDHB
Uniprot ID:
P11177
Reactions
Pyruvic acid + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine unknown [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2)details
Pyruvic acid + Thiamine pyrophosphate unknown 2-(a-Hydroxyethyl)thiamine diphosphate + Carbon dioxidedetails
Pyruvic acid + Enzyme N6-(lipoyl)lysine unknown [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Carbon dioxidedetails
Gene Name:
PC
Uniprot ID:
P11498
Reactions
Adenosine triphosphate + Pyruvic acid + Carbonic acid unknown ADP + Phosphoric acid + Oxalacetic aciddetails
Gene Name:
PDHA1
Uniprot ID:
P08559
Reactions
Pyruvic acid + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine unknown [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2)details
Pyruvic acid + Thiamine pyrophosphate unknown 2-(a-Hydroxyethyl)thiamine diphosphate + Carbon dioxidedetails
Pyruvic acid + Enzyme N6-(lipoyl)lysine unknown [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Carbon dioxidedetails
Gene Name:
PDHA2
Uniprot ID:
P29803
Reactions
Pyruvic acid + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine unknown [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO(2)details
Pyruvic acid + Thiamine pyrophosphate unknown 2-(a-Hydroxyethyl)thiamine diphosphate + Carbon dioxidedetails
Pyruvic acid + Enzyme N6-(lipoyl)lysine unknown [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Carbon dioxidedetails
Gene Name:
DAO
Uniprot ID:
P14920
Gene Name:
AGXT2
Uniprot ID:
Q9BYV1
Reactions
L-Alanine + Glyoxylic acid unknown Pyruvic acid + Glycinedetails
(R)-b-aminoisobutyric acid + Pyruvic acid unknown 2-Methyl-3-oxopropanoic acid + L-Alaninedetails
Gene Name:
CCBL1
Uniprot ID:
Q16773
Reactions
RS-CH(2)-CH(NH(3)(+))COO(-) + Water unknown RSH + Ammonia + Pyruvic aciddetails
Gene Name:
CTH
Uniprot ID:
P32929
Reactions
L-Cysteine + Water unknown Hydrogen sulfide + Pyruvic acid + Ammoniadetails
L-Cystine + Water unknown Pyruvic acid + Ammonia + Thiocysteinedetails
Gene Name:
SDS
Uniprot ID:
P20132
Reactions
L-Serine unknown Pyruvic acid + Ammoniadetails
Gene Name:
ADCY7
Uniprot ID:
P51828
Gene Name:
ADCY4
Uniprot ID:
Q8NFM4
Gene Name:
ADCY6
Uniprot ID:
O43306
Gene Name:
ADCY5
Uniprot ID:
O95622
Gene Name:
ADCY8
Uniprot ID:
P40145
Gene Name:
ADCY9
Uniprot ID:
O60503
Gene Name:
ADCY3
Uniprot ID:
O60266
Gene Name:
ADCY1
Uniprot ID:
Q08828
Gene Name:
PKM
Uniprot ID:
P14618
Reactions
Adenosine triphosphate + Pyruvic acid unknown ADP + Phosphoenolpyruvic aciddetails
Guanosine triphosphate + Pyruvic acid unknown Guanosine diphosphate + Phosphoenolpyruvic aciddetails
Deoxyadenosine triphosphate + Pyruvic acid unknown dADP + Phosphoenolpyruvic aciddetails
dGTP + Pyruvic acid unknown dGDP + Phosphoenolpyruvic aciddetails
Nucleoside triphosphate + Pyruvic acid unknown NDP + Phosphoenolpyruvic aciddetails
Gene Name:
PKLR
Uniprot ID:
P30613
Reactions
Adenosine triphosphate + Pyruvic acid unknown ADP + Phosphoenolpyruvic aciddetails
Guanosine triphosphate + Pyruvic acid unknown Guanosine diphosphate + Phosphoenolpyruvic aciddetails
Deoxyadenosine triphosphate + Pyruvic acid unknown dADP + Phosphoenolpyruvic aciddetails
dGTP + Pyruvic acid unknown dGDP + Phosphoenolpyruvic aciddetails
Nucleoside triphosphate + Pyruvic acid unknown NDP + Phosphoenolpyruvic aciddetails
Gene Name:
MPST
Uniprot ID:
P25325
Reactions
3-Mercaptopyruvic acid + Hydrogen cyanide unknown Pyruvic acid + Thiocyanatedetails
3-Mercaptopyruvic acid + Sulfurous acid unknown Thiosulfate + Pyruvic aciddetails
Gene Name:
AGXT
Uniprot ID:
P21549
Reactions
L-Serine + Pyruvic acid unknown Hydroxypyruvic acid + L-Alaninedetails
L-Alanine + Glyoxylic acid unknown Pyruvic acid + Glycinedetails
Gene Name:
GPT
Uniprot ID:
P24298
Reactions
L-Alanine + Oxoglutaric acid unknown Pyruvic acid + L-Glutamic aciddetails
Gene Name:
ME1
Uniprot ID:
P48163
Reactions
L-Malic acid + NADP unknown Pyruvic acid + CO(2) + NADPHdetails
Oxalacetic acid unknown Pyruvic acid + CO(2)details
L-Malic acid + NADP unknown Pyruvic acid + Carbon dioxide + NADPH + Hydrogen Iondetails
Gene Name:
ME3
Uniprot ID:
Q16798
Reactions
L-Malic acid + NADP unknown Pyruvic acid + CO(2) + NADPHdetails
Oxalacetic acid unknown Pyruvic acid + CO(2)details
L-Malic acid + NADP unknown Pyruvic acid + Carbon dioxide + NADPH + Hydrogen Iondetails
Gene Name:
ME2
Uniprot ID:
P23368
Reactions
L-Malic acid + NAD unknown Pyruvic acid + CO(2) + NADHdetails
Oxalacetic acid unknown Pyruvic acid + CO(2)details
L-Malic acid + NAD unknown Pyruvic acid + Carbon dioxide + NADH + Hydrogen Iondetails
Gene Name:
HDC
Uniprot ID:
P19113
Gene Name:
LDHAL6A
Uniprot ID:
Q6ZMR3
Reactions
L-Lactic acid + NAD unknown Pyruvic acid + NADHdetails
L-Lactic acid + NAD unknown Pyruvic acid + NADH + Hydrogen Iondetails
Gene Name:
ADCY2
Uniprot ID:
Q08462
Gene Name:
TST
Uniprot ID:
Q16762
Reactions
3-Mercaptopyruvic acid + Sulfurous acid unknown Thiosulfate + Pyruvic aciddetails
Hydrogen cyanide + 3-Mercaptopyruvic acid unknown Thiocyanate + Pyruvic aciddetails
Gene Name:
SLC16A8
Uniprot ID:
O95907
Gene Name:
SLC16A6
Uniprot ID:
O15403
Gene Name:
SLC16A5
Uniprot ID:
O15375
Gene Name:
SLC16A4
Uniprot ID:
O15374
Gene Name:
LDHB
Uniprot ID:
P07195
Reactions
L-Lactic acid + NAD unknown Pyruvic acid + NADHdetails
L-Lactic acid + NAD unknown Pyruvic acid + NADH + Hydrogen Iondetails
Gene Name:
LDHC
Uniprot ID:
P07864
Reactions
L-Lactic acid + NAD unknown Pyruvic acid + NADHdetails
L-Lactic acid + NAD unknown Pyruvic acid + NADH + Hydrogen Iondetails
Gene Name:
LDHA
Uniprot ID:
P00338
Reactions
L-Lactic acid + NAD unknown Pyruvic acid + NADHdetails
L-Lactic acid + NAD unknown Pyruvic acid + NADH + Hydrogen Iondetails
Gene Name:
LDHAL6B
Uniprot ID:
Q9BYZ2
Reactions
L-Lactic acid + NAD unknown Pyruvic acid + NADHdetails
L-Lactic acid + NAD unknown Pyruvic acid + NADH + Hydrogen Iondetails
Gene Name:
LDHD
Uniprot ID:
Q86WU2
Reactions
D-Lactic acid + ferricytochrome c unknown Pyruvic acid + ferrocytochrome c + Hydrogen Iondetails
D-Lactic acid + Ferricytochrome c unknown Pyruvic acid + Ferrocytochrome c + Hydrogen Iondetails
Gene Name:
GPT2
Uniprot ID:
Q8TD30
Reactions
L-Alanine + Oxoglutaric acid unknown Pyruvic acid + L-Glutamic aciddetails
Gene Name:
SCLY
Uniprot ID:
Q96I15
Reactions
Se-Methylselenocysteine + Water unknown Pyruvic acid + Ammonia + Methaneselenoldetails
Gene Name:
NPL
Uniprot ID:
Q9BXD5
Reactions
N-Acetylneuraminic acid unknown N-Acetylmannosamine + Pyruvic aciddetails
Gene Name:
ILVBL
Uniprot ID:
A1L0T0
Gene Name:
ME3
Uniprot ID:
Q8TBJ0
Gene Name:
FAHD1
Uniprot ID:
Q6P587
Reactions
A 3-acylpyruvate + Water unknown a carboxylate + Pyruvic aciddetails
3-Fumarylpyruvate + Water unknown Fumaric acid + Pyruvic aciddetails
Gene Name:
CCBL2
Uniprot ID:
Q6YP21
Reactions
RS-CH(2)-CH(NH(3)(+))COO(-) + Water unknown RSH + Ammonia + Pyruvic aciddetails

Transporters

Gene Name:
SLC16A3
Uniprot ID:
O15427
Gene Name:
SLC16A1
Uniprot ID:
P53985
Gene Name:
SLC16A2
Uniprot ID:
P36021
Gene Name:
SLC16A7
Uniprot ID:
O60669
Gene Name:
SLC16A10
Uniprot ID:
Q8TF71

Only showing the first 50 proteins. There are 59 proteins in total.