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Record Information
Version4.0
StatusExpected but not Quantified
Creation Date2012-09-11 20:49:47 UTC
Update Date2018-03-12 21:55:10 UTC
HMDB IDHMDB0035807
Secondary Accession Numbers
  • HMDB35807
Metabolite Identification
Common NameNitrous oxide
DescriptionNitrous oxide, also known as laughing gas or N2O, belongs to the class of inorganic compounds known as other non-metal nitrides. These are inorganic compounds of nitrogen where nitrogen has a formal oxidation state of -3, and the heaviest atom bonded to it belongs to the class of 'other non-metals'. Within the cell, nitrous oxide is primarily located in the cytoplasm. Nitrous oxide has an odorless taste.
Structure
Thumb
Synonyms
ValueSource
Diazyne 1-oxideChEBI
Dinitrogen monoxideChEBI
DistickstoffmonoxidChEBI
e942ChEBI
Factitious airChEBI
Gaz hilarantChEBI
LachgasChEBI
Laughing gasChEBI
N2OChEBI
Nitrogen protoxideChEBI
Nitrogenium oxydulatumChEBI
NNOChEBI
Oxyde nitreuxChEBI
Protoxyde d'azoteChEBI
R-744aChEBI
Stickstoff(I)-oxidChEBI
Dinitrogen oxideHMDB
FEMA 2779HMDB
Gas, laughingHMDB
Hyponitrous acid anhydrideHMDB
NitralHMDB
Nitrogen hypoxideHMDB
Nitrogen monoxideHMDB
Nitrogen oxide (N2O)HMDB
Nitrous oxide (JP15/usp)HMDB
Nitrous oxide, compressedHMDB
Nitrous oxide, jan, usanHMDB
Nitrous oxide, refrigerated liquidHMDB
Nitrous-oxideHMDB
Oxide, nitrousHMDB
oxido NitrosoHMDB
Oxidodinitrogen(N--N)HMDB
StickdioxydHMDB
Chemical FormulaN2O
Average Molecular Weight44.0128
Monoisotopic Molecular Weight44.001062632
IUPAC Namediazooxidane
Traditional Namenitrous oxide
CAS Registry Number10024-97-2
SMILES
[O-][N+]#N
InChI Identifier
InChI=1S/N2O/c1-2-3
InChI KeyGQPLMRYTRLFLPF-UHFFFAOYSA-N
Chemical Taxonomy
DescriptionThis compound belongs to the class of inorganic compounds known as other non-metal nitrides. These are inorganic compounds of nitrogen where nitrogen has a formal oxidation state of -3, and the heaviest atom bonded to it belongs to the class of 'other non-metals'.
KingdomInorganic compounds
Super ClassHomogeneous non-metal compounds
ClassOther non-metal organides
Sub ClassOther non-metal nitrides
Direct ParentOther non-metal nitrides
Alternative Parents
Substituents
  • Other non-metal nitride
  • Inorganic nitride
  • Inorganic oxide
Molecular FrameworkNot Available
External Descriptors
Ontology
Disposition

Source:

Biological location:

Role

Environmental role:

Industrial application:

Biological role:

Physical Properties
StateLiquid
Experimental Properties
PropertyValueReference
Melting Point-90.6 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogP0.36Not Available
Predicted Properties
PropertyValueSource
logP-0.021ChemAxon
pKa (Strongest Basic)-6.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area54.46 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity27.67 m³·mol⁻¹ChemAxon
Polarizability2.54 ųChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positivesplash10-0006-9000000000-eb7b02e9ea0e132b0a58View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-004l-9000000000-c53ff0d270e0310b3375View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-004i-9000000000-c8b9d8f80d3f41ad7f54View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-002f-9000000000-12c3fe456373daff732eView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0002-9000000000-2eee7435817186856ef7View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-001j-9000000000-d1a5381e3dd214cad7abView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-000t-9000000000-3ae2e01e3d626729760bView in MoNA
Biological Properties
Cellular Locations
  • Cytoplasm
  • Extracellular
Biospecimen LocationsNot Available
Tissue LocationsNot Available
Pathways
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDDB06690
Phenol Explorer Compound IDNot Available
FoodDB IDFDB014561
KNApSAcK IDNot Available
Chemspider ID14487442
KEGG Compound IDC00887
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNitrous_oxide
METLIN IDNot Available
PubChem Compound948
PDB IDNot Available
ChEBI ID17045
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Landauer B: [Anesthesia for ambulatory patients]. Fortschr Med. 1975 Nov 13;93(32):1573-80. [PubMed:1220997 ]
  2. Niijima K, Seto A, Uehara H, Takenaka I, Kadoya T: [Anesthetic management for an adult patient with secundum atrial septal defect associated with a large left-to-right shunt]. Masui. 2000 Jun;49(6):646-8. [PubMed:10885245 ]
  3. Erhardt W: [Anesthesia procedures in the rabbit]. Tierarztl Prax. 1984;12(3):391-402. [PubMed:6388029 ]
  4. LICHTENSTEIN ME, METHOD H: Edmund Andrews, M.D., a biographical sketch with historical notes concerning nitrousoxide oxygen anesthesia. Q Bull Northwest Univ Med Sch. 1953;27(4):337-52. [PubMed:13112367 ]
  5. Makkes PC, Jonker MJ, Turk T: [Nitrous-oxide sedation indispensable in the dental care of anxious people and the mentally impaired]. Ned Tijdschr Geneeskd. 2006 May 13;150(19):1055-8. [PubMed:16733980 ]
  6. Lanz E, Zimmerschitt W: [Volume and pressure changes due to nitrousoxide diffusion in costumary and in low-pressure cuffs of endotracheal tubes (author's transl)]. Anaesthesist. 1976 Oct;25(10):491-8. [PubMed:984380 ]
  7. (). Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.. .