| Record Information |
|---|
| Version |
3.5 |
| Creation Date |
2005-11-16 08:48:42 -0700 |
| Update Date |
2013-05-13 17:04:08 -0600 |
| HMDB ID |
HMDB01106 |
| Secondary Accession Numbers |
None |
| Metabolite Identification |
|---|
| Common Name |
3-Aminopropionaldehyde |
| Description |
3-Aminopropanal is a reactive aldehyde that mediates progressive neuronal necrosis and glial apoptosis. (PMID 11943872  ). Increased activity of polyamine oxidase catabolizes polyamines (such as spermine, spermidine and putrescine) to produce 3-aminopropanal. (PMID 15246852 ). |
| Structure |
Download:
MOL |
SDF |
SMILES |
InChI
Display:
2D Structure |
3D Structure
|
| Synonyms |
- 3-Aminopropanal
- 3-Aminopropionaldehyde
- beta-Aminopropion aldehyde
|
| Chemical Formula |
C3H7NO |
| Average Molecular Weight |
73.0938 |
| Monoisotopic Molecular Weight |
73.052763851 |
| IUPAC Name |
3-aminopropanal |
| Traditional IUPAC Name |
3-aminopropanal |
| CAS Registry Number |
352-92-1 |
| SMILES |
NCCC=O |
| InChI Identifier |
InChI=1S/C3H7NO/c4-2-1-3-5/h3H,1-2,4H2 |
| InChI Key |
PCXDJQZLDDHMGX-UHFFFAOYSA-N |
| Chemical Taxonomy |
|---|
| Kingdom |
Organic Compounds |
| Super Class |
Aliphatic Acyclic Compounds |
| Class |
Alkylamines |
| Sub Class |
N/A |
| Other Descriptors |
- Aldehydes
- propanals(ChEBI)
|
| Substituents |
|
| Direct Parent |
Alkylamines |
| Ontology |
|---|
| Status |
Expected and Not Quantified |
| Origin |
|
| Biofunction |
Not Available |
| Application |
Not Available |
| Cellular locations |
- Cytoplasm (predicted from logP)
|
| Physical Properties |
|---|
| State |
Solid |
| Experimental Properties |
| Property |
Value |
Reference |
| Melting Point |
Not Available |
Not Available |
| Boiling Point |
Not Available |
Not Available |
| Water Solubility |
Not Available |
Not Available |
| LogP |
Not Available |
Not Available |
|
| Predicted Properties |
|
| Spectra |
|---|
|
Not Available
|
| Biological Properties |
|---|
| Cellular Locations |
- Cytoplasm (predicted from logP)
|
| Biofluid Locations |
Not Available
|
| Tissue Location |
Not Available
|
| Pathways |
|
| Normal Concentrations |
|---|
|
Not Available |
| Abnormal Concentrations |
|---|
|
Not Available |
| Associated Disorders and Diseases |
|---|
| Disease References |
None |
| Associated OMIM IDs |
None |
| External Links |
|---|
| DrugBank ID |
Not Available |
| Phenol Explorer Compound ID |
Not Available |
| Phenol Explorer Metabolite ID |
Not Available |
| FoodDB ID |
FDB022427 |
| KNApSAcK ID |
Not Available |
| Chemspider ID |
74 |
| KEGG Compound ID |
C05665 |
| BioCyc ID |
3-AMINO-PROPANAL |
| BiGG ID |
46232 |
| Wikipedia Link |
Not Available |
| NuGOwiki Link |
HMDB01106 |
| Metagene Link |
HMDB01106 |
| METLIN ID |
6007 |
| PubChem Compound |
75 |
| PDB ID |
Not Available |
| ChEBI ID |
18090 |
| References |
|---|
| Synthesis Reference |
Bott, Kaspar. Amidomethylation of trichloroethylene and acetylene: syntheses of N-protected a-chloro-b-alanines and b-aminopropanals. Journal of the Chemical Society [Section] D: Chemical Communications (1969), (22), 1304. |
| Material Safety Data Sheet (MSDS) |
Not Available
|
| General References |
Not Available
|
