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Record Information
Version5.0
StatusExpected but not Quantified
Creation Date2005-11-16 15:48:42 UTC
Update Date2021-09-14 15:44:40 UTC
HMDB IDHMDB0001351
Secondary Accession Numbers
  • HMDB01351
Metabolite Identification
Common NameDeoxyribose 1-phosphate
DescriptionDeoxyribose 1-phosphate belongs to the class of organic compounds known as pentoses. These are monosaccharides in which the carbohydrate moiety contains five carbon atoms. A Deoxyribose 1-phosphate with D-ribofuranose as the sugar. Deoxyribose 1-phosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). Deoxyribose 1-phosphate exists in all living species, ranging from bacteria to humans.
Structure
Data?1582752194
Synonyms
ValueSource
2-Deoxy-1-O-phosphono-D-erythro-pentofuranoseChEBI
2-Deoxy-1-O-phosphono-D-ribofuranoseChEBI
2-Deoxy-D-ribose 1-phosphateChEBI
2-Deoxy-D-ribose 1-phosphoric acidGenerator
Deoxyribose 1-phosphoric acidGenerator
2-Deoxy-alpha-D-ribose 1-phosphateHMDB
2-Deoxy-alpha-delta-ribose 1-phosphateHMDB
2-Deoxy-D-erythro-pentofuranose 1-phosphateHMDB
2-Deoxy-D-ribose-1-phosphateHMDB
2-Deoxy-delta-erythro-pentofuranose 1-phosphateHMDB
2-Deoxy-delta-ribose 1-phosphateHMDB
2-Deoxy-delta-ribose-1-phosphateHMDB
2-Deoxyribofuranose 1-phosphateHMDB
D-2-Deoxy-ribofuranose 1-phosphateHMDB
delta-2-Deoxy-ribofuranose 1-phosphateHMDB
Deoxyribose-1-phosphateHMDB
2-Deoxyribose 1-phosphateHMDB
2-Deoxyribose 1-phosphate, (alpha-D-erythro)-isomerHMDB
2-Deoxyribose 1-phosphate, (beta-D-erythro)-isomerHMDB
Chemical FormulaC5H11O7P
Average Molecular Weight214.1104
Monoisotopic Molecular Weight214.024239218
IUPAC Name{[(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}phosphonic acid
Traditional Namedeoxyribose-1-phosphate
CAS Registry Number17210-42-3
SMILES
OC[C@H]1OC(C[C@@H]1O)OP(O)(O)=O
InChI Identifier
InChI=1S/C5H11O7P/c6-2-4-3(7)1-5(11-4)12-13(8,9)10/h3-7H,1-2H2,(H2,8,9,10)/t3-,4+,5?/m0/s1
InChI KeyKBDKAJNTYKVSEK-PYHARJCCSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as pentoses. These are monosaccharides in which the carbohydrate moiety contains five carbon atoms.
KingdomOrganic compounds
Super ClassOrganic oxygen compounds
ClassOrganooxygen compounds
Sub ClassCarbohydrates and carbohydrate conjugates
Direct ParentPentoses
Alternative Parents
Substituents
  • Pentose monosaccharide
  • Monoalkyl phosphate
  • Alkyl phosphate
  • Phosphoric acid ester
  • Organic phosphoric acid derivative
  • Tetrahydrofuran
  • Secondary alcohol
  • Oxacycle
  • Organoheterocyclic compound
  • Organic oxide
  • Hydrocarbon derivative
  • Primary alcohol
  • Alcohol
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External Descriptors
Ontology
Not AvailableNot Available
Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
PropertyValueSource
Water Solubility37.6 g/LALOGPS
logP-2.1ALOGPS
logP-1.5ChemAxon
logS-0.76ALOGPS
pKa (Strongest Acidic)1.37ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count4ChemAxon
Polar Surface Area116.45 ŲChemAxon
Rotatable Bond Count3ChemAxon
Refractivity39.32 m³·mol⁻¹ChemAxon
Polarizability17.21 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DarkChem[M+H]+148.09531661259
DarkChem[M-H]-141.38531661259
AllCCS[M+H]+146.58932859911
AllCCS[M-H]-138.19732859911
DeepCCS[M+H]+128.59730932474
DeepCCS[M-H]-126.20130932474
DeepCCS[M-2H]-160.61830932474
DeepCCS[M+Na]+136.11630932474
AllCCS[M+H]+146.632859911
AllCCS[M+H-H2O]+142.732859911
AllCCS[M+NH4]+150.232859911
AllCCS[M+Na]+151.332859911
AllCCS[M-H]-138.232859911
AllCCS[M+Na-2H]-139.132859911
AllCCS[M+HCOO]-140.132859911

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
Deoxyribose 1-phosphateOC[C@H]1OC(C[C@@H]1O)OP(O)(O)=O2908.4Standard polar33892256
Deoxyribose 1-phosphateOC[C@H]1OC(C[C@@H]1O)OP(O)(O)=O1745.1Standard non polar33892256
Deoxyribose 1-phosphateOC[C@H]1OC(C[C@@H]1O)OP(O)(O)=O1851.7Semi standard non polar33892256

Derivatized

Derivative Name / StructureSMILESKovats RI ValueColumn TypeReference
Deoxyribose 1-phosphate,1TMS,isomer #1C[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O)C[C@@H]1O1921.6Semi standard non polar33892256
Deoxyribose 1-phosphate,1TMS,isomer #2C[Si](C)(C)O[C@H]1CC(OP(=O)(O)O)O[C@@H]1CO1916.1Semi standard non polar33892256
Deoxyribose 1-phosphate,1TMS,isomer #3C[Si](C)(C)OP(=O)(O)OC1C[C@H](O)[C@@H](CO)O11893.8Semi standard non polar33892256
Deoxyribose 1-phosphate,2TMS,isomer #1C[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O)C[C@@H]1O[Si](C)(C)C1937.6Semi standard non polar33892256
Deoxyribose 1-phosphate,2TMS,isomer #2C[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O[Si](C)(C)C)C[C@@H]1O1958.7Semi standard non polar33892256
Deoxyribose 1-phosphate,2TMS,isomer #3C[Si](C)(C)O[C@H]1CC(OP(=O)(O)O[Si](C)(C)C)O[C@@H]1CO1945.4Semi standard non polar33892256
Deoxyribose 1-phosphate,2TMS,isomer #4C[Si](C)(C)OP(=O)(OC1C[C@H](O)[C@@H](CO)O1)O[Si](C)(C)C1890.0Semi standard non polar33892256
Deoxyribose 1-phosphate,3TMS,isomer #1C[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O[Si](C)(C)C)C[C@@H]1O[Si](C)(C)C1962.6Semi standard non polar33892256
Deoxyribose 1-phosphate,3TMS,isomer #1C[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O[Si](C)(C)C)C[C@@H]1O[Si](C)(C)C1920.3Standard non polar33892256
Deoxyribose 1-phosphate,3TMS,isomer #1C[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O[Si](C)(C)C)C[C@@H]1O[Si](C)(C)C2412.0Standard polar33892256
Deoxyribose 1-phosphate,3TMS,isomer #2C[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)C[C@@H]1O1951.0Semi standard non polar33892256
Deoxyribose 1-phosphate,3TMS,isomer #2C[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)C[C@@H]1O2001.0Standard non polar33892256
Deoxyribose 1-phosphate,3TMS,isomer #2C[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)C[C@@H]1O2336.7Standard polar33892256
Deoxyribose 1-phosphate,3TMS,isomer #3C[Si](C)(C)O[C@H]1CC(OP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@@H]1CO1933.8Semi standard non polar33892256
Deoxyribose 1-phosphate,3TMS,isomer #3C[Si](C)(C)O[C@H]1CC(OP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@@H]1CO1937.1Standard non polar33892256
Deoxyribose 1-phosphate,3TMS,isomer #3C[Si](C)(C)O[C@H]1CC(OP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@@H]1CO2216.5Standard polar33892256
Deoxyribose 1-phosphate,4TMS,isomer #1C[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)C[C@@H]1O[Si](C)(C)C1952.1Semi standard non polar33892256
Deoxyribose 1-phosphate,4TMS,isomer #1C[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)C[C@@H]1O[Si](C)(C)C1976.2Standard non polar33892256
Deoxyribose 1-phosphate,4TMS,isomer #1C[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)C[C@@H]1O[Si](C)(C)C2144.8Standard polar33892256
Deoxyribose 1-phosphate,1TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O)C[C@@H]1O2159.8Semi standard non polar33892256
Deoxyribose 1-phosphate,1TBDMS,isomer #2CC(C)(C)[Si](C)(C)O[C@H]1CC(OP(=O)(O)O)O[C@@H]1CO2163.1Semi standard non polar33892256
Deoxyribose 1-phosphate,1TBDMS,isomer #3CC(C)(C)[Si](C)(C)OP(=O)(O)OC1C[C@H](O)[C@@H](CO)O12134.4Semi standard non polar33892256
Deoxyribose 1-phosphate,2TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O)C[C@@H]1O[Si](C)(C)C(C)(C)C2374.6Semi standard non polar33892256
Deoxyribose 1-phosphate,2TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O[Si](C)(C)C(C)(C)C)C[C@@H]1O2386.1Semi standard non polar33892256
Deoxyribose 1-phosphate,2TBDMS,isomer #3CC(C)(C)[Si](C)(C)O[C@H]1CC(OP(=O)(O)O[Si](C)(C)C(C)(C)C)O[C@@H]1CO2374.9Semi standard non polar33892256
Deoxyribose 1-phosphate,2TBDMS,isomer #4CC(C)(C)[Si](C)(C)OP(=O)(OC1C[C@H](O)[C@@H](CO)O1)O[Si](C)(C)C(C)(C)C2333.2Semi standard non polar33892256
Deoxyribose 1-phosphate,3TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O[Si](C)(C)C(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C2616.5Semi standard non polar33892256
Deoxyribose 1-phosphate,3TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O[Si](C)(C)C(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C2513.5Standard non polar33892256
Deoxyribose 1-phosphate,3TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O)O[Si](C)(C)C(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C2700.6Standard polar33892256
Deoxyribose 1-phosphate,3TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)C[C@@H]1O2590.3Semi standard non polar33892256
Deoxyribose 1-phosphate,3TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)C[C@@H]1O2588.9Standard non polar33892256
Deoxyribose 1-phosphate,3TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)C[C@@H]1O2643.7Standard polar33892256
Deoxyribose 1-phosphate,3TBDMS,isomer #3CC(C)(C)[Si](C)(C)O[C@H]1CC(OP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@@H]1CO2588.7Semi standard non polar33892256
Deoxyribose 1-phosphate,3TBDMS,isomer #3CC(C)(C)[Si](C)(C)O[C@H]1CC(OP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@@H]1CO2513.1Standard non polar33892256
Deoxyribose 1-phosphate,3TBDMS,isomer #3CC(C)(C)[Si](C)(C)O[C@H]1CC(OP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@@H]1CO2535.4Standard polar33892256
Deoxyribose 1-phosphate,4TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C2781.3Semi standard non polar33892256
Deoxyribose 1-phosphate,4TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C2657.3Standard non polar33892256
Deoxyribose 1-phosphate,4TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC[C@H]1OC(OP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C2560.1Standard polar33892256
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted GC-MSPredicted GC-MS Spectrum - Deoxyribose 1-phosphate GC-MS (Non-derivatized) - 70eV, Positivesplash10-0002-9100000000-0b83a26b67c41b7ca8c92016-09-22Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Deoxyribose 1-phosphate GC-MS (2 TMS) - 70eV, Positivesplash10-0002-9120000000-ed5a733798dcf4d7c4392017-10-06Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Deoxyribose 1-phosphate GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 10V, Positive-QTOFsplash10-00kb-9430000000-ef11f7c98a651dbe59d72015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 20V, Positive-QTOFsplash10-0002-9400000000-5e3754bb21aff6c3ce062015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 40V, Positive-QTOFsplash10-0002-9300000000-615ca1fa907e42aa9c9d2015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 10V, Negative-QTOFsplash10-03fs-9260000000-5a7b6b1faaba56e1c97d2015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 20V, Negative-QTOFsplash10-004i-9100000000-5f0b0b093f8d726f70762015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 40V, Negative-QTOFsplash10-004i-9000000000-b1cd1b026728c07d36bb2015-09-15Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 10V, Positive-QTOFsplash10-014i-3690000000-41b666017994305912b82021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 20V, Positive-QTOFsplash10-0002-9200000000-99440f284bdeb59e2f042021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 40V, Positive-QTOFsplash10-052b-9000000000-f613851350f97d5430bc2021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 10V, Negative-QTOFsplash10-03fr-9080000000-e66a31856a5562cb0b9d2021-09-25Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 20V, Negative-QTOFsplash10-004i-9000000000-a5e502a2627af2048a1f2021-09-25Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Deoxyribose 1-phosphate 40V, Negative-QTOFsplash10-004i-9000000000-a5e502a2627af2048a1f2021-09-25Wishart LabView Spectrum

NMR Spectra

Spectrum TypeDescriptionDeposition DateSourceView
Predicted 1D NMR13C NMR Spectrum (1D, 100 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 100 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 1000 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 1000 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 200 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 200 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 300 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 300 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 400 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 400 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 500 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 500 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 600 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 600 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 700 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 700 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 800 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 800 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 900 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 900 MHz, H2O, predicted)2022-08-18Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Cytoplasm (predicted from logP)
Biospecimen LocationsNot Available
Tissue LocationsNot Available
Pathways
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB022571
KNApSAcK IDNot Available
Chemspider ID388420
KEGG Compound IDC00672
BioCyc IDNot Available
BiGG ID35664
Wikipedia LinkNot Available
METLIN ID6182
PubChem Compound439287
PDB IDNot Available
ChEBI ID28542
Food Biomarker OntologyNot Available
VMH ID2DR1P
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Holmberg I, Stal P, Hamberg M: Quantitative determination of 8-hydroxy-2'-deoxyguanosine in human urine by isotope dilution mass spectrometry: normal levels in hemochromatosis. Free Radic Biol Med. 1999 Jan;26(1-2):129-35. [PubMed:9890648 ]

Enzymes

General function:
Involved in ribokinase activity
Specific function:
Not Available
Gene Name:
RBKS
Uniprot ID:
Q9H477
Molecular weight:
34142.685
General function:
Involved in intramolecular transferase activity, phosphotransferases
Specific function:
Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity.
Gene Name:
PGM2
Uniprot ID:
Q96G03
Molecular weight:
68282.765
Reactions
Deoxyribose 1-phosphate → Deoxyribose 5-phosphatedetails
Deoxyribose 1-phosphate → Deoxyribose 5-monophosphatedetails
General function:
Involved in purine-nucleoside phosphorylase activity
Specific function:
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
Gene Name:
PNP
Uniprot ID:
P00491
Molecular weight:
32117.69
Reactions
Deoxyguanosine + Phosphate → Guanine + Deoxyribose 1-phosphatedetails
Deoxyuridine + Phosphate → Uracil + Deoxyribose 1-phosphatedetails
Deoxyadenosine + Phosphate → Adenine + Deoxyribose 1-phosphatedetails
Deoxyinosine + Phosphate → Hypoxanthine + Deoxyribose 1-phosphatedetails
General function:
Involved in transferase activity, transferring glycosyl groups
Specific function:
May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro. Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Gene Name:
TYMP
Uniprot ID:
P19971
Molecular weight:
49954.965
Reactions
Thymidine + Phosphate → Thymine + Deoxyribose 1-phosphatedetails
Deoxyuridine + Phosphate → Uracil + Deoxyribose 1-phosphatedetails
Fluorouracil + Deoxyribose 1-phosphate → Floxuridine + Phosphatedetails