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Human Metabolome Database Version 3.5

Showing metabocard for Guanosine monophosphate (HMDB01397)

• Identification
• Taxonomy
• Ontology
• Physical properties
• Spectra
• Biological properties
• Concentrations
• Links
• References

enzymes (194)

• Blood
• Urine

Record Information
Version	3.5
Creation Date	2005-11-16 08:48:42 -0700
Update Date	2013-02-08 17:10:28 -0700
HMDB ID	HMDB01397
Secondary Accession Numbers	None
Metabolite Identification
Common Name	Guanosine monophosphate
Description	Guanosine 5'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Structure	Download: MOL | SDF | SMILES | InChI Display: 2D Structure | 3D Structure
Synonyms	5'-GMP E 626 GMP Guanidine monophosphate Guanosine 5'-monophosphate Guanosine 5'-phosphate Guanosine 5'-phosphorate Guanosine 5'-phosphoric acid Guanosine monophosphate Guanosine-5'-monophosphate Guanosine-5'-phosphate Guanosine-phosphate Guanylate Guanylic acid
Chemical Formula	C10H14N5O8P
Average Molecular Weight	363.2206
Monoisotopic Molecular Weight	363.057998961
IUPAC Name	{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Traditional IUPAC Name	[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxyphosphonic acid
CAS Registry Number	85-32-5
SMILES	NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1
InChI Identifier	InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChI Key	RQFCJASXJCIDSX-UUOKFMHZSA-N
Chemical Taxonomy
Kingdom	Organic Compounds
Super Class	Nucleosides, Nucleotides, and Analogues
Class	Purine Nucleotides
Sub Class	Purine Ribonucleotides
Other Descriptors	Aromatic Heteropolycyclic Compounds
Substituents	1,2 Diol 1 Phosphoribosyl Imidazole Aminopyrimidine Glycosyl Compound Hypoxanthine Imidazole Imidazopyrimidine Monosaccharide Phosphate N Glycosyl Compound Organic Hypophosphite Organic Phosphite Oxolane Pentose Monosaccharide Phosphoric Acid Ester Purine Purinone Pyrimidine Pyrimidone Saccharide Secondary Alcohol
Direct Parent	Purine Ribonucleoside Monophosphates
Ontology
Status	Detected and Quantified
Origin	Endogenous
Biofunction	Component of Glutamate metabolism Component of Purine metabolism Component of Pyrimidine metabolism Second messenger
Application	Not Available
Cellular locations	Extracellular Mitochondria Nucleus Lysosome Golgi apparatus
Physical Properties
State	Solid
Experimental Properties	Property Value Reference Melting Point Not Available Not Available Boiling Point Not Available Not Available Water Solubility 369 mg/mL Not Available LogP Not Available Not Available
Predicted Properties	Property Value Source Water Solubility 3.56 g/L ALOGPS LogP -1.99 ALOGPS LogP -2.9 ChemAxon LogS -2.01 ALOGPS pKa (strongest acidic) 1.05 ChemAxon pKa (strongest basic) 1.73 ChemAxon Hydrogen Acceptor Count 10 ChemAxon Hydrogen Donor Count 6 ChemAxon Polar Surface Area 201.75 A2 ChemAxon Rotatable Bond Count 4 ChemAxon Refractivity 75.49 ChemAxon Polarizability 30.7 ChemAxon Formal Charge 0 ChemAxon Physiological Charge -2 ChemAxon
Spectra
	1H NMR Spectrum MS/MS Spectrum Quattro_QQQ 10 MS/MS Spectrum Quattro_QQQ 25 MS/MS Spectrum Quattro_QQQ 40 MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) 30 MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) MS/MS Spectrum GC-MS [1H,13C] 2D NMR Spectrum
Biological Properties
Cellular Locations	Extracellular Mitochondria Nucleus Lysosome Golgi apparatus
Biofluid Locations	Blood
Tissue Location	Bladder Intestine Neuron Epidermis Nerve Cells Platelet Heart Smooth Muscle
Pathways	Name SMPDB Link KEGG Link Transcription/Translation SMP00019 Not Available Purine Metabolism SMP00050 map00230 Glutamate Metabolism SMP00072 map00250
Normal Concentrations
	Biofluid Status Value Age Sex Condition Comments Blood Detected and Quantified 0.0099 +/- 0.0024 uM Adult (>18 years old) Male Normal Not Available Blood Detected and Quantified 0.0095 +/- 0.0021 uM Adult (>18 years old) Female Normal Not Available
Abnormal Concentrations
	Not Available
Associated Disorders and Diseases
Disease References	None
Associated OMIM IDs	None
External Links
DrugBank ID	DB01972
Phenol Explorer Compound ID	Not Available
Phenol Explorer Metabolite ID	Not Available
FoodDB ID	FDB012390
KNApSAcK ID	C00019635
Chemspider ID	6545
KEGG Compound ID	C00144
BioCyc ID	GMP
BiGG ID	34024
Wikipedia Link	GMP
NuGOwiki Link	HMDB01397
Metagene Link	HMDB01397
METLIN ID	6216
PubChem Compound	6804
PDB ID	5GP
ChEBI ID	17345
References
Synthesis Reference	Sato, Katsuaki; Matsui, Hiroshi; Ei, Hitoshi; Takinami, Koichi. Guanosine-5'-monophosphate. Jpn. Kokai Tokkyo Koho (1979), 3 pp.
Material Safety Data Sheet (MSDS)	Download (PDF)
General References	Matata BM, Galinanes M: Effect of diabetes on nitric oxide metabolism during cardiac surgery. Diabetes. 2001 Nov;50(11):2603-10. Pubmed: 11679441 Sales ME, Espanol AJ, Sterin-Borda L, Borda E, de Bracco MM: Protein kinase C regulates NO-cGMP pathway in muscarinic receptor activation by HIV+-IgA. Int J Mol Med. 1999 Jun;3(6):633-7. Pubmed: 10341295 Scheen AJ: [Medication of the month. Vardenafil (Levitra)] Rev Med Liege. 2003 Sep;58(9):576-9. Pubmed: 14626653 Boehning D, Moon C, Sharma S, Hurt KJ, Hester LD, Ronnett GV, Shugar D, Snyder SH: Carbon monoxide neurotransmission activated by CK2 phosphorylation of heme oxygenase-2. Neuron. 2003 Sep 25;40(1):129-37. Pubmed: 14527438 Begonja AJ, Gambaryan S, Geiger J, Aktas B, Pozgajova M, Nieswandt B, Walter U: Platelet NAD(P)H-oxidase-generated ROS production regulates alphaIIbbeta3-integrin activation independent of the NO/cGMP pathway. Blood. 2005 Oct 15;106(8):2757-60. Epub 2005 Jun 23. Pubmed: 15976180 Favory R, Lancel S, Tissier S, Mathieu D, Decoster B, Neviere R: Myocardial dysfunction and potential cardiac hypoxia in rats induced by carbon monoxide inhalation. Am J Respir Crit Care Med. 2006 Aug 1;174(3):320-5. Epub 2006 May 11. Pubmed: 16690979 Yildiz O, Gul H, Ozgok Y, Onguru O, Kilciler M, Aydin A, Isimer A, Harmankaya AC: Increased vasoconstrictor reactivity and decreased endothelial function in high grade varicocele; functional and morphological study. Urol Res. 2003 Oct;31(5):323-8. Epub 2003 Jul 11. Pubmed: 14574537 Seftel AD: Phosphodiesterase type 5 inhibitor differentiation based on selectivity, pharmacokinetic, and efficacy profiles. Clin Cardiol. 2004 Apr;27(4 Suppl 1):I14-19. Pubmed: 15115191 Salomon P, Przewlocka-Kosmala M, Orda A: [Plasma levels of brain natriuretic peptide, cyclic 3'5'-guanosine monophosphate, endothelin 1, and noradrenaline in patients with chronic congestive heart failure] Pol Arch Med Wewn. 2003 Jan;109(1):43-8. Pubmed: 12879765 Khush KK, De Marco T, Vakharia KT, Harmon C, Fineman JR, Chatterjee K, Michaels AD: Nesiritide acutely increases pulmonary and systemic levels of nitric oxide in patients with pulmonary hypertension. J Card Fail. 2006 Sep;12(7):507-13. Pubmed: 16952783 Yoshimura N, Seki S, Chancellor MB, de Groat WC, Ueda T: Targeting afferent hyperexcitability for therapy of the painful bladder syndrome. Urology. 2002 May;59(5 Suppl 1):61-7. Pubmed: 12007524 Ralph DJ: Normal erectile function. Clin Cornerstone. 2005;7(1):13-8. Pubmed: 16156419 Rosen RC, McKenna KE: PDE-5 inhibition and sexual response: pharmacological mechanisms and clinical outcomes. Annu Rev Sex Res. 2002;13:36-88. Pubmed: 12836729 Zhao L, Gray L, Leonardi-Bee J, Weaver CS, Heptinstall S, Bath PM: Effect of aspirin, clopidogrel and dipyridamole on soluble markers of vascular function in normal volunteers and patients with prior ischaemic stroke. Platelets. 2006 Mar;17(2):100-4. Pubmed: 16421011 Zusman RM, Morales A, Glasser DB, Osterloh IH: Overall cardiovascular profile of sildenafil citrate. Am J Cardiol. 1999 Mar 4;83(5A):35C-44C. Pubmed: 10078541 Hamed EA, Meki AR, Gaafar AA, Hamed SA: Role of some vasoactive mediators in patients with erectile dysfunction: their relationship with angiotensin-converting enzyme and growth hormone. Int J Impot Res. 2003 Dec;15(6):418-25. Pubmed: 14671660 Ehsan A, Sommer F, Schmidt A, Klotz T, Koslowski J, Niggemann S, Jacobs G, Engelmann U, Addicks K, Bloch W: Nitric oxide pathways in human bladder carcinoma. The distribution of nitric oxide synthases, soluble guanylyl cyclase, cyclic guanosine monophosphate, and nitrotyrosine. Cancer. 2002 Dec 1;95(11):2293-301. Pubmed: 12436434 Lepore JJ, Maroo A, Bigatello LM, Dec GW, Zapol WM, Bloch KD, Semigran MJ: Hemodynamic effects of sildenafil in patients with congestive heart failure and pulmonary hypertension: combined administration with inhaled nitric oxide. Chest. 2005 May;127(5):1647-53. Pubmed: 15888841 Kekilli M, Beyazit Y, Purnak T, Dogan S, Atalar E: Acute myocardial infarction after sildenafil citrate ingestion. Ann Pharmacother. 2005 Jul-Aug;39(7-8):1362-4. Epub 2005 May 24. Pubmed: 15914518 Ivanovic Z, Duchez P, Dazey B, Hermitte F, Lamrissi-Garcia I, Mazurier F, Praloran V, Reiffers J, Vezon G, Boiron JM: A clinical-scale expansion of mobilized CD 34+ hematopoietic stem and progenitor cells by use of a new serum-free medium. Transfusion. 2006 Jan;46(1):126-31. Pubmed: 16398741

---

Enzymes
Name: Cytosolic 5'-nucleotidase 1B Reactions: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate [RN:R07297] Gene Name: NT5C1B Uniprot ID: Q96P26 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cytosolic 5'-nucleotidase 1A Reactions: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate [RN:R07297] Gene Name: NT5C1A Uniprot ID: Q9BXI3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 5'(3')-deoxyribonucleotidase, cytosolic type Reactions: Gene Name: NT5C Uniprot ID: Q8TCD5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 5'(3')-deoxyribonucleotidase, mitochondrial Reactions: Gene Name: NT5M Uniprot ID: Q9NPB1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 1 Reactions: ATP + 2 H2O = AMP + 2 phosphate [RN:R00085] Gene Name: ENTPD1 Uniprot ID: P49961 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Soluble calcium-activated nucleotidase 1 Reactions: a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329] Gene Name: CANT1 Uniprot ID: Q8WVQ1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 3 Reactions: ATP + 2 H2O = AMP + 2 phosphate [RN:R00085] Gene Name: ENTPD3 Uniprot ID: O75355 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Inosine triphosphate pyrophosphatase Reactions: a nucleoside triphosphate + H2O = a nucleotide + diphosphate [RN:R01532] Gene Name: ITPA Uniprot ID: Q9BY32 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Adenine phosphoribosyltransferase Reactions: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate [RN:R00190] Gene Name: APRT Uniprot ID: P07741 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Hypoxanthine-guanine phosphoribosyltransferase Reactions: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate [RN:R01132] Gene Name: HPRT1 Uniprot ID: P00492 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE6H Uniprot ID: Q13956 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE1A Uniprot ID: P54750 Protein Sequence: FASTA Gene Sequence: FASTA
Name: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE8A Uniprot ID: O60658 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE1B Uniprot ID: Q01064 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cGMP-inhibited 3',5'-cyclic phosphodiesterase B Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE3B Uniprot ID: Q13370 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' Reactions: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate [RN:R01234] Gene Name: PDE6C Uniprot ID: P51160 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GMP synthase [glutamine-hydrolyzing] Reactions: ATP + xanthosine 5'-phosphate + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate [RN:R01231] Gene Name: GMPS Uniprot ID: P49915 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cGMP-inhibited 3',5'-cyclic phosphodiesterase A Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE3A Uniprot ID: Q14432 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Reactions: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate [RN:R01234] Gene Name: PDE10A Uniprot ID: Q9Y233 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE1C Uniprot ID: Q14123 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4B Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE4B Uniprot ID: Q07343 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 7B Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE7B Uniprot ID: Q9NP56 Protein Sequence: FASTA Gene Sequence: FASTA
Name: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A Reactions: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate [RN:R01234] Gene Name: PDE9A Uniprot ID: O76083 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cGMP-dependent 3',5'-cyclic phosphodiesterase Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE2A Uniprot ID: O00408 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Reactions: P1,P4-bis(5'-guanosyl) tetraphosphate + H2O = GTP + GMP [RN:R01232] Gene Name: NUDT2 Uniprot ID: P50583 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Reactions: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate [RN:R01234] Gene Name: PDE6A Uniprot ID: P16499 Protein Sequence: FASTA Gene Sequence: FASTA
Name: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE8B Uniprot ID: O95263 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4C Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE4C Uniprot ID: Q08493 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta Reactions: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate [RN:R01234] Gene Name: PDE6B Uniprot ID: P35913 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4D Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE4D Uniprot ID: Q08499 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE6G Uniprot ID: P18545 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta Reactions: Gene Name: PDE6D Uniprot ID: O43924 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4A Reactions: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate [RN:R03259] Gene Name: PDE4A Uniprot ID: P27815 Protein Sequence: FASTA Gene Sequence: FASTA
Name: cGMP-specific 3',5'-cyclic phosphodiesterase Reactions: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate [RN:R01234] Gene Name: PDE5A Uniprot ID: O76074 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein-glutamine gamma-glutamyltransferase E Reactions: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3 [RN:R03983] Gene Name: TGM3 Uniprot ID: Q08188 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GMP reductase 2 Reactions: inosine 5'-phosphate + NH3 + NADP+ = guanosine 5'-phosphate + NADPH + H+ [RN:R01134] Gene Name: GMPR2 Uniprot ID: Q9P2T1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GMP reductase 1 Reactions: inosine 5'-phosphate + NH3 + NADP+ = guanosine 5'-phosphate + NADPH + H+ [RN:R01134] Gene Name: GMPR Uniprot ID: P36959 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 6 Reactions: a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329] Gene Name: ENTPD6 Uniprot ID: O75354 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 5 Reactions: a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329] Gene Name: ENTPD5 Uniprot ID: O75356 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Bifunctional purine biosynthesis protein PURH Reactions: IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide [RN:R01127] Gene Name: ATIC Uniprot ID: P31939 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanylate kinase Reactions: ATP + GMP = ADP + GDP [RN:R00332] Gene Name: GUK1 Uniprot ID: Q16774 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Atrial natriuretic peptide receptor 2 Reactions: GTP = 3',5'-cyclic GMP + diphosphate [RN:R00434] Gene Name: NPR2 Uniprot ID: P20594 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Atrial natriuretic peptide receptor 1 Reactions: GTP = 3',5'-cyclic GMP + diphosphate [RN:R00434] Gene Name: NPR1 Uniprot ID: P16066 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Heat-stable enterotoxin receptor Reactions: GTP = 3',5'-cyclic GMP + diphosphate [RN:R00434] Gene Name: GUCY2C Uniprot ID: P25092 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cyclic nucleotide-gated cation channel alpha-3 Reactions: Gene Name: CNGA3 Uniprot ID: Q16281 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 2 Reactions: Gene Name: RAPGEF2 Uniprot ID: Q9Y4G8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Disks large homolog 4 Reactions: Gene Name: DLG4 Uniprot ID: P78352 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Histidine triad nucleotide-binding protein 1 Reactions: Gene Name: HINT1 Uniprot ID: P49773 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 1 Reactions: Gene Name: ARHGEF1 Uniprot ID: Q92888 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Reactions: Gene Name: GNG2 Uniprot ID: P59768 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related C3 botulinum toxin substrate 1 Reactions: Gene Name: RAC1 Uniprot ID: P63000 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Reactions: Gene Name: GNAS Uniprot ID: P63092 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Proto-oncogene DBL Reactions: Gene Name: MCF2 Uniprot ID: P10911 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cell division control protein 42 homolog Reactions: Gene Name: CDC42 Uniprot ID: P60953 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related C3 botulinum toxin substrate 2 Reactions: Gene Name: RAC2 Uniprot ID: P15153 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Vinexin Reactions: Gene Name: SORBS3 Uniprot ID: O60504 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTPase HRas Reactions: Gene Name: HRAS Uniprot ID: P01112 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho-related GTP-binding protein RhoQ Reactions: Gene Name: RHOQ Uniprot ID: P17081 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(q) subunit alpha Reactions: Gene Name: GNAQ Uniprot ID: P50148 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-11 Reactions: Gene Name: GNA11 Uniprot ID: P29992 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Reactions: Gene Name: GNG11 Uniprot ID: P61952 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(t) subunit alpha-1 Reactions: Gene Name: GNAT1 Uniprot ID: P11488 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein ALEX Reactions: Gene Name: GNAS Uniprot ID: P84996 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 3 Reactions: Gene Name: RAPGEF3 Uniprot ID: O95398 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lysophosphatidic acid receptor 2 Reactions: Gene Name: LPAR2 Uniprot ID: Q9HBW0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 4 Reactions: Gene Name: RAPGEF4 Uniprot ID: Q8WZA2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cytosolic 5'-nucleotidase 3 Reactions: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate [RN:R07297] Gene Name: NT5C3 Uniprot ID: Q9H0P0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: ENTPD4 protein Reactions: Gene Name: ENTPD4 Uniprot ID: Q8NE73 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Reactions: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate [RN:R01234] Gene Name: PDE11A Uniprot ID: Q9HCR9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Reactions: Gene Name: PREX1 Uniprot ID: Q8TCU6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 8 Reactions: ATP + 2 H2O = AMP + 2 phosphate [RN:R00085] Gene Name: ENTPD8 Uniprot ID: Q5MY95 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Synembryn-B Reactions: Gene Name: RIC8B Uniprot ID: Q9NVN3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 6 Reactions: Gene Name: RAPGEF6 Uniprot ID: Q8TEU7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Neuroepithelial cell-transforming gene 1 protein Reactions: Gene Name: NET1 Uniprot ID: Q7Z628 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cell cycle progression protein 1 Reactions: Gene Name: CCPG1 Uniprot ID: Q9ULG6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Reactions: Gene Name: PREX2 Uniprot ID: Q70Z35 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 10 Reactions: Gene Name: DOCK10 Uniprot ID: Q96BY6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 1 Reactions: Gene Name: DOCK1 Uniprot ID: Q14185 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 2 Reactions: Gene Name: DOCK2 Uniprot ID: Q92608 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 3 Reactions: Gene Name: DOCK3 Uniprot ID: Q8IZD9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 4 Reactions: Gene Name: DOCK4 Uniprot ID: Q8N1I0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 5 Reactions: Gene Name: DOCK5 Uniprot ID: Q9H7D0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 6 Reactions: Gene Name: DOCK6 Uniprot ID: Q96HP0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 7 Reactions: Gene Name: DOCK7 Uniprot ID: Q96N67 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 8 Reactions: Gene Name: DOCK8 Uniprot ID: Q8NF50 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTPase-activating protein and VPS9 domain-containing protein 1 Reactions: Gene Name: GAPVD1 Uniprot ID: Q14C86 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Reactions: Gene Name: GNB1 Uniprot ID: P62873 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Reactions: Gene Name: GNB2 Uniprot ID: P62879 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Reactions: Gene Name: GNB3 Uniprot ID: P16520 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit beta-4 Reactions: Gene Name: GNB4 Uniprot ID: Q9HAV0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit beta-5 Reactions: Gene Name: GNB5 Uniprot ID: O14775 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Reactions: Gene Name: GNG10 Uniprot ID: P50151 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Reactions: Gene Name: GNG12 Uniprot ID: Q9UBI6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Reactions: Gene Name: GNG13 Uniprot ID: Q9P2W3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(T) subunit gamma-T1 Reactions: Gene Name: GNGT1 Uniprot ID: P63211 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Reactions: Gene Name: GNG3 Uniprot ID: P63215 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Reactions: Gene Name: GNG4 Uniprot ID: P50150 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Reactions: Gene Name: GNG5 Uniprot ID: P63218 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Reactions: Gene Name: GNG7 Uniprot ID: O60262 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Reactions: Gene Name: GNG8 Uniprot ID: Q9UK08 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Reactions: Gene Name: GNGT2 Uniprot ID: O14610 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein-like 1 Reactions: Gene Name: GNL1 Uniprot ID: P36915 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Probable E3 ubiquitin-protein ligase HERC1 Reactions: Gene Name: HERC1 Uniprot ID: Q15751 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Eukaryotic translation initiation factor 5 Reactions: Gene Name: EIF5 Uniprot ID: P55010 Protein Sequence: FASTA Gene Sequence: FASTA
Name: IQ motif and SEC7 domain-containing protein 1 Reactions: Gene Name: IQSEC1 Uniprot ID: Q6DN90 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor DBS Reactions: Gene Name: MCF2L Uniprot ID: O15068 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related protein Rab-5A Reactions: Gene Name: RAB5A Uniprot ID: P20339 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related protein Rab-5B Reactions: Gene Name: RAB5B Uniprot ID: P61020 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ran-binding protein 3 Reactions: Gene Name: RANBP3 Uniprot ID: Q9H6Z4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ral guanine nucleotide dissociation stimulator-like 2 Reactions: Gene Name: RGL2 Uniprot ID: O15211 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ral guanine nucleotide dissociation stimulator-like 3 Reactions: Gene Name: RGL3 Uniprot ID: Q3MIN7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Synembryn-A Reactions: Gene Name: RIC8A Uniprot ID: Q9NPQ8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras and Rab interactor 1 Reactions: Gene Name: RIN1 Uniprot ID: Q13671 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras and Rab interactor 2 Reactions: Gene Name: RIN2 Uniprot ID: Q8WYP3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras and Rab interactor 3 Reactions: Gene Name: RIN3 Uniprot ID: Q8TB24 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTP-binding protein Rit1 Reactions: Gene Name: RIT1 Uniprot ID: Q92963 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTP-binding protein Rit2 Reactions: Gene Name: RIT2 Uniprot ID: Q99578 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 5 Reactions: Gene Name: RAPGEF5 Uniprot ID: Q92565 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related GTP-binding protein A Reactions: Gene Name: RRAGA Uniprot ID: Q7L523 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related GTP-binding protein B Reactions: Gene Name: RRAGB Uniprot ID: Q5VZM2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related GTP-binding protein C Reactions: Gene Name: RRAGC Uniprot ID: Q9HB90 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related GTP-binding protein D Reactions: Gene Name: RRAGD Uniprot ID: Q9NQL2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Secretion-regulating guanine nucleotide exchange factor Reactions: Gene Name: SERGEF Uniprot ID: Q9UGK8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: T-lymphoma invasion and metastasis-inducing protein 2 Reactions: Gene Name: TIAM2 Uniprot ID: Q8IVF5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein XRP2 Reactions: Gene Name: RP2 Uniprot ID: O75695 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho-related GTP-binding protein RhoU Reactions: Gene Name: RHOU Uniprot ID: Q7L0Q8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(i) subunit alpha-1 Reactions: Gene Name: GNAI1 Uniprot ID: P63096 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Reactions: Gene Name: GNAS Uniprot ID: Q5JWF2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor VAV2 Reactions: Gene Name: VAV2 Uniprot ID: P52735 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho-guanine nucleotide exchange factor Reactions: Gene Name: RGNEF Uniprot ID: Q8N1W1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras guanyl-releasing protein 3 Reactions: Gene Name: RASGRP3 Uniprot ID: Q8IV61 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein RCC2 Reactions: Gene Name: RCC2 Uniprot ID: Q9P258 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein very KIND Reactions: Gene Name: KNDC1 Uniprot ID: Q76NI1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Abl interactor 1 Reactions: Gene Name: ABI1 Uniprot ID: Q8IZP0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTP-binding protein SAR1b Reactions: Gene Name: SAR1B Uniprot ID: Q9Y6B6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-GEF domain-containing family member 1A Reactions: Gene Name: RASGEF1A Uniprot ID: Q8N9B8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: G-protein-signaling modulator 1 Reactions: Gene Name: GPSM1 Uniprot ID: Q86YR5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTP-binding protein GEM Reactions: Gene Name: GEM Uniprot ID: P55040 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor-like 1 Reactions: Gene Name: RAPGEFL1 Uniprot ID: Q9UHV5 Protein Sequence: FASTA
Name: Guanine nucleotide binding protein-like 1 Reactions: Gene Name: GNL1 Uniprot ID: B0V0L1 Protein Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 6 Reactions: Gene Name: ARHGEF6 Uniprot ID: Q15052 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-14 Reactions: Gene Name: GNA14 Uniprot ID: O95837 Protein Sequence: FASTA Gene Sequence: FASTA
Name: PH and SEC7 domain-containing protein 4 Reactions: Gene Name: PSD4 Uniprot ID: Q8NDX1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 9 Reactions: Gene Name: ARHGEF9 Uniprot ID: O43307 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(k) subunit alpha Reactions: Gene Name: GNAI3 Uniprot ID: P08754 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Epithelial cell-transforming sequence 2 oncogene-like Reactions: Gene Name: ECT2L Uniprot ID: Q008S8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pleckstrin homology domain-containing family G member 6 Reactions: Gene Name: PLEKHG6 Uniprot ID: Q3KR16 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(i) subunit alpha-2 Reactions: Gene Name: GNAI2 Uniprot ID: P04899 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(t) subunit alpha-2 Reactions: Gene Name: GNAT2 Uniprot ID: P19087 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 37 Reactions: Gene Name: ARHGEF37 Uniprot ID: A1IGU5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: PH and SEC7 domain-containing protein 3 Reactions: Gene Name: PSD3 Uniprot ID: Q9NYI0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: PH and SEC7 domain-containing protein 1 Reactions: Gene Name: PSD Uniprot ID: A5PKW4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(o) subunit alpha Reactions: Gene Name: GNAO1 Uniprot ID: P09471 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-GEF domain-containing family member 1B Reactions: Gene Name: RASGEF1B Uniprot ID: Q0VAM2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 18 Reactions: Gene Name: ARHGEF18 Uniprot ID: Q6ZSZ5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: ALS2 C-terminal-like protein Reactions: Gene Name: ALS2CL Uniprot ID: Q60I27 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Switch-associated protein 70 Reactions: Gene Name: SWAP70 Uniprot ID: Q9UH65 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-specific guanine nucleotide-releasing factor RalGPS2 Reactions: Gene Name: RALGPS2 Uniprot ID: Q86X27 Protein Sequence: FASTA Gene Sequence: FASTA
Name: FERM, RhoGEF and pleckstrin domain-containing protein 2 Reactions: Gene Name: FARP2 Uniprot ID: O94887 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ral guanine nucleotide dissociation stimulator-like 1 Reactions: Gene Name: RGL1 Uniprot ID: Q9NZL6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-13 Reactions: Gene Name: GNA13 Uniprot ID: Q14344 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Vav-like protein C9orf100 Reactions: Gene Name: C9orf100 Uniprot ID: Q8N4T4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Probable guanine nucleotide exchange factor MCF2L2 Reactions: Gene Name: MCF2L2 Uniprot ID: Q86YR7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 7 Reactions: Gene Name: ARHGEF7 Uniprot ID: Q14155 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein (G protein), alpha 14 Reactions: Gene Name: GNA14 Uniprot ID: B1ALW3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein-like 1 Reactions: Gene Name: GNL1 Uniprot ID: A2AB27 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-12 Reactions: Gene Name: GNA12 Uniprot ID: Q03113 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-specific guanine nucleotide-releasing factor RalGPS1 Reactions: Gene Name: RALGPS1 Uniprot ID: Q5JS13 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 11 Reactions: Gene Name: ARHGEF11 Uniprot ID: O15085 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Growth factor receptor-bound protein 2 Reactions: Gene Name: GRB2 Uniprot ID: P62993 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein (G protein), beta polypeptide 1 Reactions: Gene Name: GNB1 Uniprot ID: B1AKQ8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 10-like protein Reactions: Gene Name: ARHGEF10L Uniprot ID: Q9HCE6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein (G protein), q polypeptide Reactions: Gene Name: GNAQ Uniprot ID: B1AM21 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein SOLO Reactions: Gene Name: SOLO Uniprot ID: Q8TER5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Prolactin regulatory element-binding protein Reactions: Gene Name: PREB Uniprot ID: Q9HCU5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 4 Reactions: Gene Name: ARHGEF4 Uniprot ID: Q9NR80 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor for Rab-3A Reactions: Gene Name: RAB3IL1 Uniprot ID: Q8TBN0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Engulfment and cell motility protein 1 Reactions: Gene Name: ELMO1 Uniprot ID: Q92556 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GRB2-related adapter protein Reactions: Gene Name: GRAP Uniprot ID: Q13588 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(z) subunit alpha Reactions: Gene Name: GNAZ Uniprot ID: P19086 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Engulfment and cell motility protein 3 Reactions: Gene Name: ELMO3 Uniprot ID: Q96BJ8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor GEFT Reactions: Gene Name: GEFT Uniprot ID: Q86VW2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Differentially expressed in FDCP 6 homolog Reactions: Gene Name: DEF6 Uniprot ID: Q9H4E7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Alpha-catulin Reactions: Gene Name: CTNNAL1 Uniprot ID: Q9UBT7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: IQ motif and SEC7 domain-containing protein 3 Reactions: Gene Name: IQSEC3 Uniprot ID: Q9UPP2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Engulfment and cell motility protein 2 Reactions: Gene Name: ELMO2 Uniprot ID: Q96JJ3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 17 Reactions: Gene Name: ARHGEF17 Uniprot ID: Q96PE2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-GEF domain-containing family member 1C Reactions: Gene Name: RASGEF1C Uniprot ID: Q8N431 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 12 Reactions: Gene Name: ARHGEF12 Uniprot ID: Q9NZN5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ephexin-1 Reactions: Gene Name: NGEF Uniprot ID: Q8N5V2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein-like 1 Reactions: Gene Name: GNL1 Uniprot ID: B0V0L0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(olf) subunit alpha Reactions: Gene Name: GNAL Uniprot ID: P38405 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-15 Reactions: Gene Name: GNA15 Uniprot ID: P30679 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 3 Reactions: Gene Name: ARHGEF3 Uniprot ID: Q9NR81 Protein Sequence: FASTA Gene Sequence: FASTA

This project is supported by Genome Alberta & Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $600 million in funding from the federal government.