Human Metabolome Database Version 3.5

Showing metabocard for Guanosine monophosphate (HMDB01397)

Record Information
Version 3.5
Creation Date 2005-11-16 08:48:42 -0700
Update Date 2013-02-08 17:10:28 -0700
HMDB ID HMDB01397
Secondary Accession Numbers None
Metabolite Identification
Common Name Guanosine monophosphate
Description Guanosine 5'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
Structure Thumb
Download: MOL | SDF | PDB | SMILES | InChI
Display: 2D Structure | 3D Structure
Synonyms
  1. 5'-GMP
  2. E 626
  3. GMP
  4. Guanidine monophosphate
  5. Guanosine 5'-monophosphate
  6. Guanosine 5'-phosphate
  7. Guanosine 5'-phosphorate
  8. Guanosine 5'-phosphoric acid
  9. Guanosine monophosphate
  10. Guanosine-5'-monophosphate
  11. Guanosine-5'-phosphate
  12. Guanosine-phosphate
  13. Guanylate
  14. Guanylic acid
Chemical Formula C10H14N5O8P
Average Molecular Weight 363.2206
Monoisotopic Molecular Weight 363.057998961
IUPAC Name {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Traditional IUPAC Name [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxyphosphonic acid
CAS Registry Number 85-32-5
SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1
InChI Identifier InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChI Key RQFCJASXJCIDSX-UUOKFMHZSA-N
Chemical Taxonomy
Kingdom Organic Compounds
Super Class Nucleosides, Nucleotides, and Analogues
Class Purine Nucleotides
Sub Class Purine Ribonucleotides
Other Descriptors
  • Aromatic Heteropolycyclic Compounds
Substituents
  • 1,2 Diol
  • 1 Phosphoribosyl Imidazole
  • Aminopyrimidine
  • Glycosyl Compound
  • Hypoxanthine
  • Imidazole
  • Imidazopyrimidine
  • Monosaccharide Phosphate
  • N Glycosyl Compound
  • Organic Hypophosphite
  • Organic Phosphite
  • Oxolane
  • Pentose Monosaccharide
  • Phosphoric Acid Ester
  • Purine
  • Purinone
  • Pyrimidine
  • Pyrimidone
  • Saccharide
  • Secondary Alcohol
Direct Parent Purine Ribonucleoside Monophosphates
Ontology
Status Detected and Quantified
Origin
  • Endogenous
Biofunction
  • Component of Glutamate metabolism
  • Component of Purine metabolism
  • Component of Pyrimidine metabolism
  • Second messenger
Application Not Available
Cellular locations
  • Extracellular
  • Mitochondria
  • Nucleus
  • Lysosome
  • Golgi apparatus
Physical Properties
State Solid
Experimental Properties
Property Value Reference
Melting Point Not Available Not Available
Boiling Point Not Available Not Available
Water Solubility 369 mg/mL Not Available
LogP Not Available Not Available
Predicted Properties
Property Value Source
Water Solubility 3.56 g/L ALOGPS
LogP -1.99 ALOGPS
LogP -2.9 ChemAxon
LogS -2.01 ALOGPS
pKa (strongest acidic) 1.05 ChemAxon
pKa (strongest basic) 1.73 ChemAxon
Hydrogen Acceptor Count 10 ChemAxon
Hydrogen Donor Count 6 ChemAxon
Polar Surface Area 201.75 A2 ChemAxon
Rotatable Bond Count 4 ChemAxon
Refractivity 75.49 ChemAxon
Polarizability 30.7 ChemAxon
Formal Charge 0 ChemAxon
Physiological Charge -2 ChemAxon
Spectra
1H NMR Spectrum
MS/MS Spectrum Quattro_QQQ 10
MS/MS Spectrum Quattro_QQQ 25
MS/MS Spectrum Quattro_QQQ 40
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters)
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) 30
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters)
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters)
MS/MS Spectrum LC-ESI-QTOF (UPLC Q-Tof Premier, Waters)
MS/MS Spectrum GC-MS
[1H,13C] 2D NMR Spectrum
Biological Properties
Cellular Locations
  • Extracellular
  • Mitochondria
  • Nucleus
  • Lysosome
  • Golgi apparatus
Biofluid Locations
  • Blood
Tissue Location
  • Bladder
  • Intestine
  • Neuron
  • Epidermis
  • Nerve Cells
  • Platelet
  • Heart
  • Smooth Muscle
Pathways
Name SMPDB Link KEGG Link
Transcription/Translation SMP00019 Not Available
Purine Metabolism SMP00050 map00230 Link_out
Glutamate Metabolism SMP00072 map00250 Link_out
Normal Concentrations
Biofluid Status Value Age Sex Condition Reference
Blood Detected and Quantified
0.0099 +/- 0.0024 uM Adult (>18 years old) Male Normal
  • Geigy Scient...
Blood Detected and Quantified
0.0095 +/- 0.0021 uM Adult (>18 years old) Female Normal
  • Geigy Scient...
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease References None
Associated OMIM IDs None
DrugBank ID DB01972 Link_out
DrugBank Metabolite ID Not Available
Phenol Explorer Compound ID Not Available
Phenol Explorer Metabolite ID Not Available
FoodDB ID FDB012390
KNApSAcK ID C00019635 Link_out
Chemspider ID 6545 Link_out
KEGG Compound ID C00144 Link_out
BioCyc ID GMP Link_out
BiGG ID 34024 Link_out
Wikipedia Link GMP Link_out
NuGOwiki Link HMDB01397 Link_out
Metagene Link HMDB01397 Link_out
METLIN ID 6216 Link_out
PubChem Compound 6804 Link_out
PDB ID 5GP Link_out
ChEBI ID 17345 Link_out
References
Synthesis Reference Sato, Katsuaki; Matsui, Hiroshi; Ei, Hitoshi; Takinami, Koichi. Guanosine-5'-monophosphate. Jpn. Kokai Tokkyo Koho (1979), 3 pp.
Material Safety Data Sheet (MSDS) Download (PDF)
General References
  1. Matata BM, Galinanes M: Effect of diabetes on nitric oxide metabolism during cardiac surgery. Diabetes. 2001 Nov;50(11):2603-10. Pubmed: 11679441 Link_out
  2. Sales ME, Espanol AJ, Sterin-Borda L, Borda E, de Bracco MM: Protein kinase C regulates NO-cGMP pathway in muscarinic receptor activation by HIV+-IgA. Int J Mol Med. 1999 Jun;3(6):633-7. Pubmed: 10341295 Link_out
  3. Scheen AJ: [Medication of the month. Vardenafil (Levitra)] Rev Med Liege. 2003 Sep;58(9):576-9. Pubmed: 14626653 Link_out
  4. Boehning D, Moon C, Sharma S, Hurt KJ, Hester LD, Ronnett GV, Shugar D, Snyder SH: Carbon monoxide neurotransmission activated by CK2 phosphorylation of heme oxygenase-2. Neuron. 2003 Sep 25;40(1):129-37. Pubmed: 14527438 Link_out
  5. Begonja AJ, Gambaryan S, Geiger J, Aktas B, Pozgajova M, Nieswandt B, Walter U: Platelet NAD(P)H-oxidase-generated ROS production regulates alphaIIbbeta3-integrin activation independent of the NO/cGMP pathway. Blood. 2005 Oct 15;106(8):2757-60. Epub 2005 Jun 23. Pubmed: 15976180 Link_out
  6. Favory R, Lancel S, Tissier S, Mathieu D, Decoster B, Neviere R: Myocardial dysfunction and potential cardiac hypoxia in rats induced by carbon monoxide inhalation. Am J Respir Crit Care Med. 2006 Aug 1;174(3):320-5. Epub 2006 May 11. Pubmed: 16690979 Link_out
  7. Yildiz O, Gul H, Ozgok Y, Onguru O, Kilciler M, Aydin A, Isimer A, Harmankaya AC: Increased vasoconstrictor reactivity and decreased endothelial function in high grade varicocele; functional and morphological study. Urol Res. 2003 Oct;31(5):323-8. Epub 2003 Jul 11. Pubmed: 14574537 Link_out
  8. Seftel AD: Phosphodiesterase type 5 inhibitor differentiation based on selectivity, pharmacokinetic, and efficacy profiles. Clin Cardiol. 2004 Apr;27(4 Suppl 1):I14-19. Pubmed: 15115191 Link_out
  9. Salomon P, Przewlocka-Kosmala M, Orda A: [Plasma levels of brain natriuretic peptide, cyclic 3'5'-guanosine monophosphate, endothelin 1, and noradrenaline in patients with chronic congestive heart failure] Pol Arch Med Wewn. 2003 Jan;109(1):43-8. Pubmed: 12879765 Link_out
  10. Khush KK, De Marco T, Vakharia KT, Harmon C, Fineman JR, Chatterjee K, Michaels AD: Nesiritide acutely increases pulmonary and systemic levels of nitric oxide in patients with pulmonary hypertension. J Card Fail. 2006 Sep;12(7):507-13. Pubmed: 16952783 Link_out
  11. Yoshimura N, Seki S, Chancellor MB, de Groat WC, Ueda T: Targeting afferent hyperexcitability for therapy of the painful bladder syndrome. Urology. 2002 May;59(5 Suppl 1):61-7. Pubmed: 12007524 Link_out
  12. Ralph DJ: Normal erectile function. Clin Cornerstone. 2005;7(1):13-8. Pubmed: 16156419 Link_out
  13. Rosen RC, McKenna KE: PDE-5 inhibition and sexual response: pharmacological mechanisms and clinical outcomes. Annu Rev Sex Res. 2002;13:36-88. Pubmed: 12836729 Link_out
  14. Zhao L, Gray L, Leonardi-Bee J, Weaver CS, Heptinstall S, Bath PM: Effect of aspirin, clopidogrel and dipyridamole on soluble markers of vascular function in normal volunteers and patients with prior ischaemic stroke. Platelets. 2006 Mar;17(2):100-4. Pubmed: 16421011 Link_out
  15. Zusman RM, Morales A, Glasser DB, Osterloh IH: Overall cardiovascular profile of sildenafil citrate. Am J Cardiol. 1999 Mar 4;83(5A):35C-44C. Pubmed: 10078541 Link_out
  16. Hamed EA, Meki AR, Gaafar AA, Hamed SA: Role of some vasoactive mediators in patients with erectile dysfunction: their relationship with angiotensin-converting enzyme and growth hormone. Int J Impot Res. 2003 Dec;15(6):418-25. Pubmed: 14671660 Link_out
  17. Ehsan A, Sommer F, Schmidt A, Klotz T, Koslowski J, Niggemann S, Jacobs G, Engelmann U, Addicks K, Bloch W: Nitric oxide pathways in human bladder carcinoma. The distribution of nitric oxide synthases, soluble guanylyl cyclase, cyclic guanosine monophosphate, and nitrotyrosine. Cancer. 2002 Dec 1;95(11):2293-301. Pubmed: 12436434 Link_out
  18. Lepore JJ, Maroo A, Bigatello LM, Dec GW, Zapol WM, Bloch KD, Semigran MJ: Hemodynamic effects of sildenafil in patients with congestive heart failure and pulmonary hypertension: combined administration with inhaled nitric oxide. Chest. 2005 May;127(5):1647-53. Pubmed: 15888841 Link_out
  19. Kekilli M, Beyazit Y, Purnak T, Dogan S, Atalar E: Acute myocardial infarction after sildenafil citrate ingestion. Ann Pharmacother. 2005 Jul-Aug;39(7-8):1362-4. Epub 2005 May 24. Pubmed: 15914518 Link_out
  20. Ivanovic Z, Duchez P, Dazey B, Hermitte F, Lamrissi-Garcia I, Mazurier F, Praloran V, Reiffers J, Vezon G, Boiron JM: A clinical-scale expansion of mobilized CD 34+ hematopoietic stem and progenitor cells by use of a new serum-free medium. Transfusion. 2006 Jan;46(1):126-31. Pubmed: 16398741 Link_out

Enzymes

Show all enzymes and transporters Important Only showing the first 50 enzymes. There are 198 enzymes in total.

Name: 5'-nucleotidase
Reactions:
Guanosine monophosphate + Water unknown Guanosine + Phosphoric acid details
Gene Name: NT5E
Uniprot ID: P21589 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cytosolic 5'-nucleotidase 1B
Reactions:
Guanosine monophosphate + Water unknown Guanosine + Phosphoric acid details
Gene Name: NT5C1B
Uniprot ID: Q96P26 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cytosolic 5'-nucleotidase 1A
Reactions:
Guanosine monophosphate + Water unknown Guanosine + Phosphoric acid details
Gene Name: NT5C1A
Uniprot ID: Q9BXI3 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: 5'(3')-deoxyribonucleotidase, cytosolic type
Reactions:
Guanosine monophosphate + Water unknown Guanosine + Phosphoric acid details
Gene Name: NT5C
Uniprot ID: Q8TCD5 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: 5'(3')-deoxyribonucleotidase, mitochondrial
Reactions:
Guanosine monophosphate + Water unknown Guanosine + Phosphoric acid details
Gene Name: NT5M
Uniprot ID: Q9NPB1 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 1
Reactions:
Guanosine diphosphate + Water unknown Guanosine monophosphate + Phosphoric acid details
Gene Name: ENTPD1
Uniprot ID: P49961 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Soluble calcium-activated nucleotidase 1
Reactions:
Guanosine diphosphate + Water unknown Guanosine monophosphate + Phosphoric acid details
Gene Name: CANT1
Uniprot ID: Q8WVQ1 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 3
Reactions:
Guanosine diphosphate + Water unknown Guanosine monophosphate + Phosphoric acid details
Gene Name: ENTPD3
Uniprot ID: O75355 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Inosine triphosphate pyrophosphatase
Reactions:
Guanosine triphosphate + Water unknown Guanosine monophosphate + Pyrophosphate details
Gene Name: ITPA
Uniprot ID: Q9BY32 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Adenine phosphoribosyltransferase
Reactions:
Guanosine monophosphate + Pyrophosphate unknown Guanine + Phosphoribosyl pyrophosphate details
Gene Name: APRT
Uniprot ID: P07741 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Hypoxanthine-guanine phosphoribosyltransferase
Reactions:
Guanosine monophosphate + Pyrophosphate unknown Guanine + Phosphoribosyl pyrophosphate details
Gene Name: HPRT1
Uniprot ID: P00492 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Reactions:
Guanosine 3',5'-cyclic phosphate + Water unknown Guanosine monophosphate details
Gene Name: PDE6H
Uniprot ID: Q13956 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE1A
Uniprot ID: P54750 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE8A
Uniprot ID: O60658 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE1B
Uniprot ID: Q01064 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cGMP-inhibited 3',5'-cyclic phosphodiesterase B
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE3B
Uniprot ID: Q13370 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
Reactions:
Guanosine 3',5'-cyclic phosphate + Water unknown Guanosine monophosphate details
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE6C
Uniprot ID: P51160 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE7A
Uniprot ID: Q13946 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: GMP synthase [glutamine-hydrolyzing]
Reactions:
Adenosine triphosphate + Xanthylic acid + L-Glutamine + Water unknown Adenosine monophosphate + Pyrophosphate + Guanosine monophosphate + L-Glutamic acid details
Adenosine triphosphate + Xanthylic acid + Ammonia unknown Adenosine monophosphate + Pyrophosphate + Guanosine monophosphate details
Gene Name: GMPS
Uniprot ID: P49915 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cGMP-inhibited 3',5'-cyclic phosphodiesterase A
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE3A
Uniprot ID: Q14432 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Reactions:
Guanosine 3',5'-cyclic phosphate + Water unknown Guanosine monophosphate details
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE10A
Uniprot ID: Q9Y233 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE1C
Uniprot ID: Q14123 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE4B
Uniprot ID: Q07343 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 7B
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE7B
Uniprot ID: Q9NP56 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Reactions:
Guanosine 3',5'-cyclic phosphate + Water unknown Guanosine monophosphate details
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE9A
Uniprot ID: O76083 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cGMP-dependent 3',5'-cyclic phosphodiesterase
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE2A
Uniprot ID: O00408 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
Reactions:
P(1),P(4)-bis(5'-guanosyl) tetraphosphate + Water unknown Guanosine triphosphate + Guanosine monophosphate details
Diguanosine tetraphosphate + Water unknown Guanosine triphosphate + Guanosine monophosphate details
Gene Name: NUDT2
Uniprot ID: P50583 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
Reactions:
Guanosine 3',5'-cyclic phosphate + Water unknown Guanosine monophosphate details
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE6A
Uniprot ID: P16499 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE8B
Uniprot ID: O95263 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4C
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE4C
Uniprot ID: Q08493 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Reactions:
Guanosine 3',5'-cyclic phosphate + Water unknown Guanosine monophosphate details
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE6B
Uniprot ID: P35913 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE4D
Uniprot ID: Q08499 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Reactions:
Guanosine 3',5'-cyclic phosphate + Water unknown Guanosine monophosphate details
Gene Name: PDE6G
Uniprot ID: P18545 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Reactions: Not Available
Gene Name: PDE6D
Uniprot ID: O43924 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4A
Reactions:
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE4A
Uniprot ID: P27815 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: cGMP-specific 3',5'-cyclic phosphodiesterase
Reactions:
Guanosine 3',5'-cyclic phosphate + Water unknown Guanosine monophosphate details
Cyclic GMP + Water unknown Guanosine monophosphate details
Gene Name: PDE5A
Uniprot ID: O76074 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Protein-glutamine gamma-glutamyltransferase E
Reactions: Not Available
Gene Name: TGM3
Uniprot ID: Q08188 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: GMP reductase 2
Reactions:
Inosinic acid + Ammonia + NADP unknown Guanosine monophosphate + NADPH details
Inosinic acid + Ammonia + NADP unknown Guanosine monophosphate + NADPH + Hydrogen Ion details
Gene Name: GMPR2
Uniprot ID: Q9P2T1 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: GMP reductase 1
Reactions:
Inosinic acid + Ammonia + NADP unknown Guanosine monophosphate + NADPH details
Inosinic acid + Ammonia + NADP unknown Guanosine monophosphate + NADPH + Hydrogen Ion details
Gene Name: GMPR
Uniprot ID: P36959 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 4
Reactions:
Guanosine diphosphate + Water unknown Guanosine monophosphate + Phosphoric acid details
Gene Name: ENTPD4
Uniprot ID: Q9Y227 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 6
Reactions:
Guanosine diphosphate + Water unknown Guanosine monophosphate + Phosphoric acid details
Gene Name: ENTPD6
Uniprot ID: O75354 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 5
Reactions:
Guanosine diphosphate + Water unknown Guanosine monophosphate + Phosphoric acid details
Gene Name: ENTPD5
Uniprot ID: O75356 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Bifunctional purine biosynthesis protein PURH
Reactions: Not Available
Gene Name: ATIC
Uniprot ID: P31939 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Guanylate kinase
Reactions:
Adenosine triphosphate + Guanosine monophosphate unknown ADP + Guanosine diphosphate details
Gene Name: GUK1
Uniprot ID: Q16774 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Atrial natriuretic peptide receptor 2
Reactions: Not Available
Gene Name: NPR2
Uniprot ID: P20594 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Atrial natriuretic peptide receptor 1
Reactions: Not Available
Gene Name: NPR1
Uniprot ID: P16066 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Heat-stable enterotoxin receptor
Reactions: Not Available
Gene Name: GUCY2C
Uniprot ID: P25092 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Cyclic nucleotide-gated cation channel alpha-3
Reactions: Not Available
Gene Name: CNGA3
Uniprot ID: Q16281 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 2
Reactions: Not Available
Gene Name: RAPGEF2
Uniprot ID: Q9Y4G8 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA
Name: Disks large homolog 4
Reactions: Not Available
Gene Name: DLG4
Uniprot ID: P78352 Link_out
Protein Sequence: FASTA
Gene Sequence: FASTA