| Record Information |
|---|
| Version |
3.5 |
| Creation Date |
2006-05-18 03:06:02 -0600 |
| Update Date |
2013-02-08 17:11:04 -0700 |
| HMDB ID |
HMDB01940 |
| Secondary Accession Numbers |
None |
| Metabolite Identification |
|---|
| Common Name |
Triamterene |
| Description |
Pteridine. A pteridine that is used as a mild diuretic. -- Pubchem; Triamterene is a potassium-sparing diuretic used in combination with thiazide diuretics for the treatment of hypertension. -- Wikipedia. |
| Structure |
Download:
MOL |
SDF |
SMILES |
InChI
Display:
2D Structure |
3D Structure
|
| Synonyms |
- 6-Phenyl-2,4,7-triaminopteridine
- Ademin
- Ademine
- Diren
- Ditak
- Diurene
- Dyren
- Dyrenium
- Dytac
- Jatropur
- Noridil
- Noridyl
- Pterofen
- Pterophene
- Taturil
- Teriam
- Teridin
- Tri-Span
- Triampur
- Triamteren
- Triamterene
- Triamteril
- Triamteril complex
- Trispan
- Triteren
|
| Chemical Formula |
C12H11N7 |
| Average Molecular Weight |
253.2626 |
| Monoisotopic Molecular Weight |
253.107593387 |
| IUPAC Name |
6-phenylpteridine-2,4,7-triamine |
| Traditional IUPAC Name |
triamterene |
| CAS Registry Number |
396-01-0 |
| SMILES |
NC1=NC(N)=C2N=C(C(N)=NC2=N1)C1=CC=CC=C1 |
| InChI Identifier |
InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19) |
| InChI Key |
FNYLWPVRPXGIIP-UHFFFAOYSA-N |
| Chemical Taxonomy |
|---|
| Kingdom |
Organic Compounds |
| Super Class |
Aromatic Heteropolycyclic Compounds |
| Class |
Pteridines and Derivatives |
| Sub Class |
N/A |
| Other Descriptors |
- Aromatic Heteropolycyclic Compounds
|
| Substituents |
- Aminopyrazine
- Aminopyrimidine
- Polyamine
- Pyrazine
- Pyrimidine
|
| Direct Parent |
Pteridines and Derivatives |
| Ontology |
|---|
| Status |
Expected and Not Quantified |
| Origin |
|
| Biofunction |
Not Available |
| Application |
Not Available |
| Cellular locations |
- Cytoplasm (predicted from logP)
|
| Physical Properties |
|---|
| State |
Solid |
| Experimental Properties |
| Property |
Value |
Reference |
| Melting Point |
316 °C |
Not Available |
| Boiling Point |
Not Available |
Not Available |
| Water Solubility |
Not Available |
Not Available |
| LogP |
0.98 |
HANSCH,C ET AL. (1995) |
|
| Predicted Properties |
|
| Spectra |
|---|
|
|
| Biological Properties |
|---|
| Cellular Locations |
- Cytoplasm (predicted from logP)
|
| Biofluid Locations |
Not Available
|
| Tissue Location |
Not Available
|
| Pathways |
Not Available
|
| Normal Concentrations |
|---|
|
Not Available |
| Abnormal Concentrations |
|---|
|
Not Available |
| Associated Disorders and Diseases |
|---|
| Disease References |
None |
| Associated OMIM IDs |
None |
| External Links |
|---|
| DrugBank ID |
Not Available |
| Phenol Explorer Compound ID |
Not Available |
| Phenol Explorer Metabolite ID |
Not Available |
| FoodDB ID |
FDB022755 |
| KNApSAcK ID |
Not Available |
| Chemspider ID |
5345  |
| KEGG Compound ID |
D00386 |
| BioCyc ID |
Not Available |
| BiGG ID |
Not Available |
| Wikipedia Link |
Triamterene |
| NuGOwiki Link |
HMDB01940 |
| Metagene Link |
HMDB01940 |
| METLIN ID |
2908 |
| PubChem Compound |
5546 |
| PDB ID |
DX2 |
| ChEBI ID |
117411 |
| References |
|---|
| Synthesis Reference |
Not Available |
| Material Safety Data Sheet (MSDS) |
Download (PDF)
|
| General References |
Not Available |
