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Record Information
Version5.0
StatusDetected and Quantified
Creation Date2006-05-22 15:12:13 UTC
Update Date2021-09-14 15:40:13 UTC
HMDB IDHMDB0002833
Secondary Accession Numbers
  • HMDB02833
Metabolite Identification
Common NameTestosterone sulfate
DescriptionTestosterone is a predominantly male hormone, though females do produce certain amounts of it. The primary female hormone is estrogen and males also produce certain amounts of this hormone. testosterone causes the appearance of male traits (i.e deepening voice, pubic and facial hairs, muscular build, etc.). The keto group on C-17 is reduced to an alcohol to yield testosterone. Testosterone is a steroid hormone from the androgen group. testosterone is primarily secreted in the testes of males and the ovaries of females although small amounts are secreted by the adrenal glands. It is the principal male sex hormone and an anabolic steroid. In both males and females, it plays key roles in health and well-being. On average, the adult male body produces about twenty times the amount of testosterone that an adult female's body does. Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5-alpha -dihydrotestosterone (DHT) by the cytoplasmic enzyme 5-alpha-reductase(5-alpha-reduktas). DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about 2.5 times that of T. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects. It is important to note that if there is a too low amount of 5-alpha-reductase(5-alfa-reduktas), the body (of a human) will continue growing into a female with testicles.
Structure
Data?1582752257
Synonyms
ValueSource
Testosterone-17beta-sulfateChEBI
Testosterone-17b-sulfateGenerator
Testosterone-17b-sulfuric acidGenerator
Testosterone-17b-sulphateGenerator
Testosterone-17b-sulphuric acidGenerator
Testosterone-17beta-sulfuric acidGenerator
Testosterone-17beta-sulphateGenerator
Testosterone-17beta-sulphuric acidGenerator
Testosterone-17β-sulfateGenerator
Testosterone-17β-sulfuric acidGenerator
Testosterone-17β-sulphateGenerator
Testosterone-17β-sulphuric acidGenerator
Testosterone sulfuric acidGenerator
Testosterone sulphateGenerator
Testosterone sulphuric acidGenerator
17-O-SulfotestosteroneHMDB
17beta-(Sulfooxy)androst-4-en-3-oneHMDB
Testosterone 17-sulfateHMDB
Testosterone 17-sulphateHMDB
Testosterone 17b-sulfateHMDB
Testosterone 17b-sulphateHMDB
Testosterone hydrogen sulfateHMDB
Testosterone hydrogen sulphateHMDB
Testosterone monosulfateHMDB
Testosterone monosulphateHMDB
Testosterone-17-sulfateHMDB
Testosterone-17-sulphateHMDB
AndroGelHMDB
AstraZeneca brand OF testosteroneHMDB
GlaxoSmithKline brand OF testosteroneHMDB
Hauck brand OF testosteroneHMDB
Schering brand OF testosteroneHMDB
TestolinHMDB
Testosterone-17-sulfate, (17alpha)-isomerHMDB
Testosterone-17-sulfate, ammonium saltHMDB
Testosterone-17-sulfate, sodium saltHMDB
17 beta Hydroxy 4 androsten 3 oneHMDB
17 beta Hydroxy 8 alpha 4 androsten 3 oneHMDB
HisteroneHMDB
SustanonHMDB
17-beta-Hydroxy-4-androsten-3-oneHMDB
Faulding brand OF testosteroneHMDB
Ferring brand OF testosteroneHMDB
8 IsotestosteroneHMDB
8-IsotestosteroneHMDB
Paladin brand OF testosteroneHMDB
Pasadena brand OF testosteroneHMDB
Solvay brand OF testosteroneHMDB
SterotateHMDB
TestosteroneHMDB
Unimed brand OF testosteroneHMDB
Dr. kade brand OF testosteroneHMDB
TestimHMDB
TestopelHMDB
AndropatchHMDB
CEPA brand OF testosteroneHMDB
Ortho brand OF testosteroneHMDB
17-beta-Hydroxy-8 alpha-4-androsten-3-oneHMDB
Auxilium pharmaceuticals inc. brand OF testosteroneHMDB
Bartor brand OF testosteroneHMDB
Ulmer brand OF testosteroneHMDB
Watson brand OF testosteroneHMDB
AndrodermHMDB
AndrotopHMDB
SmithKline beecham brand OF testosteroneHMDB
TestodermHMDB
Chemical FormulaC19H28O5S
Average Molecular Weight368.488
Monoisotopic Molecular Weight368.165744696
IUPAC Name[(1S,2R,10R,11S,14S,15S)-2,15-dimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl]oxidanesulfonic acid
Traditional Nametestosterone sulfate
CAS Registry Number651-45-6
SMILES
[H][C@@]12CC[C@H](OS(O)(=O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C
InChI Identifier
InChI=1S/C19H28O5S/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(24-25(21,22)23)19(15,2)10-8-16(14)18/h11,14-17H,3-10H2,1-2H3,(H,21,22,23)/t14-,15-,16-,17-,18-,19-/m0/s1
InChI KeyWAQBISPOEAOCOG-DYKIIFRCSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as sulfated steroids. These are sterol lipids containing a sulfate group attached to the steroid skeleton.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassSteroids and steroid derivatives
Sub ClassSulfated steroids
Direct ParentSulfated steroids
Alternative Parents
Substituents
  • Sulfated steroid skeleton
  • Androgen-skeleton
  • Androstane-skeleton
  • 3-oxo-delta-4-steroid
  • 3-oxosteroid
  • Oxosteroid
  • Delta-4-steroid
  • Cyclohexenone
  • Sulfuric acid ester
  • Alkyl sulfate
  • Sulfate-ester
  • Sulfuric acid monoester
  • Organic sulfuric acid or derivatives
  • Ketone
  • Cyclic ketone
  • Organic oxygen compound
  • Carbonyl group
  • Organooxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Aliphatic homopolycyclic compound
Molecular FrameworkAliphatic homopolycyclic compounds
External Descriptors
Ontology
Physiological effectNot Available
Disposition
Biological locationRoute of exposureSource
Process
Role
Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting Point155 - 156 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic PropertiesNot Available
Predicted Molecular Properties
PropertyValueSource
Water Solubility0.007 g/LALOGPS
logP0.13ALOGPS
logP3.42ChemAxon
logS-4.7ALOGPS
pKa (Strongest Acidic)-1.3ChemAxon
pKa (Strongest Basic)-4.8ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area80.67 ŲChemAxon
Rotatable Bond Count2ChemAxon
Refractivity94.42 m³·mol⁻¹ChemAxon
Polarizability39.59 ųChemAxon
Number of Rings4ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DarkChem[M+H]+187.81431661259
DarkChem[M-H]-181.33431661259
DeepCCS[M-2H]-219.07130932474
DeepCCS[M+Na]+194.21630932474
AllCCS[M+H]+189.132859911
AllCCS[M+H-H2O]+186.632859911
AllCCS[M+NH4]+191.432859911
AllCCS[M+Na]+192.132859911
AllCCS[M-H]-187.332859911
AllCCS[M+Na-2H]-187.732859911
AllCCS[M+HCOO]-188.332859911

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
Testosterone sulfate[H][C@@]12CC[C@H](OS(O)(=O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C4187.7Standard polar33892256
Testosterone sulfate[H][C@@]12CC[C@H](OS(O)(=O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C2792.4Standard non polar33892256
Testosterone sulfate[H][C@@]12CC[C@H](OS(O)(=O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C3305.6Semi standard non polar33892256

Derivatized

Derivative Name / StructureSMILESKovats RI ValueColumn TypeReference
Testosterone sulfate,1TMS,isomer #1C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2OS(=O)(=O)O[Si](C)(C)C3217.4Semi standard non polar33892256
Testosterone sulfate,1TMS,isomer #1C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2OS(=O)(=O)O[Si](C)(C)C3168.3Standard non polar33892256
Testosterone sulfate,1TMS,isomer #1C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2OS(=O)(=O)O[Si](C)(C)C3756.3Standard polar33892256
Testosterone sulfate,1TMS,isomer #2C[C@]12CC[C@H]3[C@@H](CCC4=CC(O[Si](C)(C)C)=CC[C@@]43C)[C@@H]1CC[C@@H]2OS(=O)(=O)O3152.3Semi standard non polar33892256
Testosterone sulfate,1TMS,isomer #2C[C@]12CC[C@H]3[C@@H](CCC4=CC(O[Si](C)(C)C)=CC[C@@]43C)[C@@H]1CC[C@@H]2OS(=O)(=O)O3024.9Standard non polar33892256
Testosterone sulfate,1TMS,isomer #2C[C@]12CC[C@H]3[C@@H](CCC4=CC(O[Si](C)(C)C)=CC[C@@]43C)[C@@H]1CC[C@@H]2OS(=O)(=O)O3854.6Standard polar33892256
Testosterone sulfate,2TMS,isomer #1C[C@]12CC[C@H]3[C@@H](CCC4=CC(O[Si](C)(C)C)=CC[C@@]43C)[C@@H]1CC[C@@H]2OS(=O)(=O)O[Si](C)(C)C3155.0Semi standard non polar33892256
Testosterone sulfate,2TMS,isomer #1C[C@]12CC[C@H]3[C@@H](CCC4=CC(O[Si](C)(C)C)=CC[C@@]43C)[C@@H]1CC[C@@H]2OS(=O)(=O)O[Si](C)(C)C3210.5Standard non polar33892256
Testosterone sulfate,2TMS,isomer #1C[C@]12CC[C@H]3[C@@H](CCC4=CC(O[Si](C)(C)C)=CC[C@@]43C)[C@@H]1CC[C@@H]2OS(=O)(=O)O[Si](C)(C)C3803.5Standard polar33892256
Testosterone sulfate,1TBDMS,isomer #1CC(C)(C)[Si](C)(C)OS(=O)(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C3432.3Semi standard non polar33892256
Testosterone sulfate,1TBDMS,isomer #1CC(C)(C)[Si](C)(C)OS(=O)(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C3450.1Standard non polar33892256
Testosterone sulfate,1TBDMS,isomer #1CC(C)(C)[Si](C)(C)OS(=O)(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C3877.9Standard polar33892256
Testosterone sulfate,1TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC1=CC[C@@]2(C)C(=C1)CC[C@H]1[C@@H]3CC[C@H](OS(=O)(=O)O)[C@@]3(C)CC[C@@H]123440.3Semi standard non polar33892256
Testosterone sulfate,1TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC1=CC[C@@]2(C)C(=C1)CC[C@H]1[C@@H]3CC[C@H](OS(=O)(=O)O)[C@@]3(C)CC[C@@H]123317.7Standard non polar33892256
Testosterone sulfate,1TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC1=CC[C@@]2(C)C(=C1)CC[C@H]1[C@@H]3CC[C@H](OS(=O)(=O)O)[C@@]3(C)CC[C@@H]123994.5Standard polar33892256
Testosterone sulfate,2TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1=CC[C@@]2(C)C(=C1)CC[C@H]1[C@@H]3CC[C@H](OS(=O)(=O)O[Si](C)(C)C(C)(C)C)[C@@]3(C)CC[C@@H]123646.7Semi standard non polar33892256
Testosterone sulfate,2TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1=CC[C@@]2(C)C(=C1)CC[C@H]1[C@@H]3CC[C@H](OS(=O)(=O)O[Si](C)(C)C(C)(C)C)[C@@]3(C)CC[C@@H]123770.1Standard non polar33892256
Testosterone sulfate,2TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1=CC[C@@]2(C)C(=C1)CC[C@H]1[C@@H]3CC[C@H](OS(=O)(=O)O[Si](C)(C)C(C)(C)C)[C@@]3(C)CC[C@@H]123974.2Standard polar33892256
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted GC-MSPredicted GC-MS Spectrum - Testosterone sulfate GC-MS (Non-derivatized) - 70eV, Positivesplash10-0f76-0479000000-bdb3d4908eb17de0bf8e2017-09-01Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Testosterone sulfate GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 10V, Positive-QTOFsplash10-014i-0039000000-3c70201ac318944d23182016-06-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 20V, Positive-QTOFsplash10-00di-0291000000-40eaf6c5a802794664832016-06-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 40V, Positive-QTOFsplash10-0udl-4973000000-432f25c70a6a5a3f7b222016-06-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 10V, Negative-QTOFsplash10-014i-0029000000-c0079f3c134f1d99c4ed2016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 20V, Negative-QTOFsplash10-00kr-1092000000-705a336c46754ed244222016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 40V, Negative-QTOFsplash10-008i-4090000000-c74eaf7f9b7239e6720b2016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 10V, Negative-QTOFsplash10-014i-0009000000-c58c9c29bacda1fca2402021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 20V, Negative-QTOFsplash10-014j-7009000000-fd0f50e05b7ebfdcc66a2021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 40V, Negative-QTOFsplash10-0002-9003000000-58fd5118dcd0e2d4f5c42021-09-22Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 10V, Positive-QTOFsplash10-014i-0019000000-810038c8bedbbf20ea252021-09-23Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 20V, Positive-QTOFsplash10-0300-0891000000-45adc8bb06a4d3a477282021-09-23Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Testosterone sulfate 40V, Positive-QTOFsplash10-0a4i-0910000000-abcfbb505d2cd01adbea2021-09-23Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Cytoplasm
  • Extracellular
  • Membrane (predicted from logP)
Biospecimen Locations
  • Blood
  • Urine
Tissue Locations
  • Brain
  • Kidney
  • Liver
  • Placenta
  • Semen
  • Skeletal Muscle
  • Testis
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodExpected but not QuantifiedNot QuantifiedNot AvailableNot AvailableNormal
      Not Available
details
UrineDetected and Quantified0.0089 (0.0056-0.012) umol/mmol creatinineAdult (>18 years old)BothNormal details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB023072
KNApSAcK IDNot Available
Chemspider ID106493
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG ID2794968
Wikipedia LinkTestosterone sulfate
METLIN ID3558
PubChem Compound119207
PDB IDNot Available
ChEBI ID84094
Food Biomarker OntologyNot Available
VMH IDTSTSTERONES
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceHolden, G. W.; Levi, I.; Bromley, R. Sodium testosterone sulfate. Journal of the American Chemical Society (1949), 71 3844.
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Takanashi K: [Studies on 2-hydroxyestradiol 17-sulfate derived from fetoplacental unit: the antioxidant as a potential defense substance against preeclampsia]. Yakugaku Zasshi. 2003 Jun;123(6):399-411. [PubMed:12822484 ]
  2. Laatikainen T, Apter D, Wahlstrom T: Steroids in spermatic and peripheral vein blood in testicular feminization. Fertil Steril. 1980 Nov;34(5):461-4. [PubMed:7439411 ]

Only showing the first 10 proteins. There are 46 proteins in total.

Enzymes

General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme has glucuronidating capacity with steroid substrates such as 5-beta-androstane 3-alpha,17-beta-diol, estradiol, ADT, eugenol and bile acids. Only isoform 1 seems to be active.
Gene Name:
UGT2B28
Uniprot ID:
Q9BY64
Molecular weight:
38742.9
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
Gene Name:
UGT2B4
Uniprot ID:
P06133
Molecular weight:
60512.035
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate.
Gene Name:
UGT1A4
Uniprot ID:
P22310
Molecular weight:
60024.535
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Its unique specificity for 3,4-catechol estrogens and estriol suggests it may play an important role in regulating the level and activity of these potent and active estrogen metabolites. Is also active with androsterone, hyodeoxycholic acid and tetrachlorocatechol (in vitro).
Gene Name:
UGT2B7
Uniprot ID:
P16662
Molecular weight:
60720.15
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.
Gene Name:
UGT2B15
Uniprot ID:
P54855
Molecular weight:
61035.815
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Active on odorants and seems to be involved in olfaction; it could help clear lipophilic odorant molecules from the sensory epithelium.
Gene Name:
UGT2A1
Uniprot ID:
Q9Y4X1
Molecular weight:
60771.605
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone.
Gene Name:
UGT1A1
Uniprot ID:
P22309
Molecular weight:
59590.91
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.
Gene Name:
UGT1A9
Uniprot ID:
O60656
Molecular weight:
59940.495
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Gene Name:
UGT1A3
Uniprot ID:
P35503
Molecular weight:
60337.835
General function:
Involved in transferase activity, transferring hexosyl groups
Specific function:
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The major substrates of this isozyme are eugenol > 4-methylumbelliferone > dihydrotestosterone (DHT) > androstane-3-alpha,17-beta-diol (3-alpha-diol) > testosterone > androsterone (ADT).
Gene Name:
UGT2B17
Uniprot ID:
O75795
Molecular weight:
61094.915

Only showing the first 10 proteins. There are 46 proteins in total.