Record Information
Version3.6
Creation Date2006-08-12 18:44:06 UTC
Update Date2013-02-09 00:12:27 UTC
HMDB IDHMDB03335
Secondary Accession NumbersNone
Metabolite Identification
Common NameIDP
DescriptionIDP is an inosine nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Structure
Thumb
Synonyms
  1. 5'-IDP
  2. IDP
  3. Inosine 5'-(trihydrogen diphosphate)
  4. Inosine 5'-(trihydrogen pyrophosphate)
  5. Inosine 5'-diphosphate
  6. Inosine 5'-pyrophosphate
  7. Inosine diphosphate
  8. Inosine pyrophosphate
  9. Riboxin
  10. Riboxine
Chemical FormulaC10H14N4O11P2
Average Molecular Weight428.1859
Monoisotopic Molecular Weight428.013430334
IUPAC Name[({[(2R,3S,4R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-3H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid
Traditional IUPAC Name{[(2R,3S,4R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methoxy(hydroxy)phosphoryl}oxyphosphonic acid
CAS Registry Number86-04-4
SMILES
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)OC([C@@H]1O)N1C=NC2=C1NC=NC2=O
InChI Identifier
InChI=1S/C10H14N4O11P2/c15-6-4(1-23-27(21,22)25-26(18,19)20)24-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10?/m1/s1
InChI KeyJPXZQMKKFWMMGK-VTHZCTBJSA-N
Chemical Taxonomy
KingdomOrganic Compounds
Super ClassNucleosides, Nucleotides, and Analogues
ClassPurine Nucleotides
Sub ClassPurine Ribonucleotides
Other Descriptors
  • Aromatic Heteropolycyclic Compounds
Substituents
  • 1,2 Diol
  • 1 Phosphoribosyl Imidazole
  • Glycosyl Compound
  • Hypoxanthine
  • Imidazole
  • Imidazopyrimidine
  • Monosaccharide Phosphate
  • N Glycosyl Compound
  • Organic Hypophosphite
  • Organic Phosphite
  • Organic Pyrophosphate
  • Oxolane
  • Pentose Monosaccharide
  • Phosphoric Acid Ester
  • Purine
  • Purinone
  • Pyrimidine
  • Pyrimidone
  • Saccharide
  • Secondary Alcohol
Direct ParentPurine Ribonucleoside Monophosphates
Ontology
StatusExpected and Not Quantified
Origin
  • Endogenous
BiofunctionNot Available
ApplicationNot Available
Cellular locations
  • Extracellular
  • Mitochondria
  • Nucleus
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
water solubility4.26 g/LALOGPS
logP-0.99ALOGPS
logP-3.6ChemAxon
logS-2ALOGPS
pKa (strongest acidic)2.65ChemAxon
pKa (strongest basic)1.73ChemAxon
physiological charge-3ChemAxon
hydrogen acceptor count12ChemAxon
hydrogen donor count6ChemAxon
polar surface area222.26ChemAxon
rotatable bond count6ChemAxon
refractivity82.64ChemAxon
polarizability33.75ChemAxon
Spectra
SpectraNot Available
Biological Properties
Cellular Locations
  • Extracellular
  • Mitochondria
  • Nucleus
Biofluid LocationsNot Available
Tissue LocationNot Available
Pathways
NameSMPDB LinkKEGG Link
Purine MetabolismSMP00050map00230
Normal Concentrations
Not Available
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDFDB023146
KNApSAcK IDNot Available
Chemspider ID559208
KEGG Compound IDC00104
BioCyc IDIDP
BiGG ID33869
Wikipedia LinkIDP
NuGOwiki LinkHMDB03335
Metagene LinkHMDB03335
METLIN ID6892
PubChem Compound644173
PDB IDNot Available
ChEBI ID17808
References
Synthesis ReferenceTakada, Masao; Kashiwa, Kenichi. Nucleoside 5'-pyrophosphates. Jpn. Tokkyo Koho (1971), 3 pp. CODEN: JAXXAD JP 46021587 19710618 Showa. CAN 75:130076 AN 1971:530076 CAPLUS
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Hlushko LV, Makovets'ka TI, Neiko IeM: [The dynamics of the glycocholic acid content of the bile in patients with chronic inactive hepatitis] Lik Sprava. 1995 May-Jun;(5-6):152-4. Pubmed: 8630789

Enzymes

Gene Name:
ENTPD1
Uniprot ID:
P49961
Reactions
Inosine triphosphate + Water unknown IDP + Phosphoric aciddetails
IDP + Water unknown Inosinic acid + Phosphoric aciddetails
Gene Name:
CANT1
Uniprot ID:
Q8WVQ1
Reactions
IDP + Water unknown Inosinic acid + Phosphoric aciddetails
Gene Name:
ENTPD3
Uniprot ID:
O75355
Reactions
Inosine triphosphate + Water unknown IDP + Phosphoric aciddetails
IDP + Water unknown Inosinic acid + Phosphoric aciddetails
Gene Name:
UCK1
Uniprot ID:
Q9HA47
Reactions
Inosine triphosphate + Cytidine unknown IDP + Cytidine monophosphatedetails
Inosine triphosphate + Uridine unknown IDP + Uridine 5'-monophosphatedetails
Gene Name:
NME4
Uniprot ID:
O00746
Reactions
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Gene Name:
NME1
Uniprot ID:
P15531
Reactions
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Gene Name:
NME7
Uniprot ID:
Q9Y5B8
Reactions
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Gene Name:
NME2
Uniprot ID:
P22392
Reactions
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Gene Name:
NME3
Uniprot ID:
Q13232
Reactions
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Gene Name:
NME6
Uniprot ID:
O75414
Reactions
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails
Gene Name:
GCK
Uniprot ID:
P35557
Gene Name:
HK3
Uniprot ID:
P52790
Gene Name:
HK2
Uniprot ID:
P52789
Gene Name:
PFKP
Uniprot ID:
Q01813
Reactions
Inosine triphosphate + D-Tagatose 6-phosphate unknown IDP + D-Tagatose 1,6-bisphosphatedetails
Gene Name:
PFKL
Uniprot ID:
P17858
Reactions
Inosine triphosphate + D-Tagatose 6-phosphate unknown IDP + D-Tagatose 1,6-bisphosphatedetails
Gene Name:
PFKM
Uniprot ID:
P08237
Reactions
Inosine triphosphate + D-Tagatose 6-phosphate unknown IDP + D-Tagatose 1,6-bisphosphatedetails
Gene Name:
PKM
Uniprot ID:
P14618
Gene Name:
PKLR
Uniprot ID:
P30613
Gene Name:
ENTPD4
Uniprot ID:
Q9Y227
Reactions
IDP + Water unknown Inosinic acid + Phosphoric aciddetails
Gene Name:
ENTPD6
Uniprot ID:
O75354
Reactions
IDP + Water unknown Inosinic acid + Phosphoric aciddetails
Gene Name:
ENTPD5
Uniprot ID:
O75356
Reactions
IDP + Water unknown Inosinic acid + Phosphoric aciddetails
Gene Name:
SUCLG1
Uniprot ID:
P53597
Reactions
Inosine triphosphate + Succinic acid + Coenzyme A unknown IDP + Phosphoric acid + Succinyl-CoAdetails
Gene Name:
PCK2
Uniprot ID:
Q16822
Reactions
Inosine triphosphate + Oxalacetic acid unknown IDP + Phosphoenolpyruvic acid + Carbon dioxidedetails
Gene Name:
SUCLG2
Uniprot ID:
Q96I99
Reactions
Inosine triphosphate + Succinic acid + Coenzyme A unknown IDP + Phosphoric acid + Succinyl-CoAdetails
Gene Name:
PCK1
Uniprot ID:
P35558
Reactions
Inosine triphosphate + Oxalacetic acid unknown IDP + Phosphoenolpyruvic acid + Carbon dioxidedetails
Gene Name:
SUCLA2
Uniprot ID:
Q9P2R7
Reactions
Inosine triphosphate + Succinic acid + Coenzyme A unknown IDP + Phosphoric acid + Succinyl-CoAdetails
Gene Name:
UCK2
Uniprot ID:
Q9BZX2
Reactions
Inosine triphosphate + Cytidine unknown IDP + Cytidine monophosphatedetails
Inosine triphosphate + Uridine unknown IDP + Uridine 5'-monophosphatedetails
Gene Name:
ENTPD4
Uniprot ID:
Q8NE73
Gene Name:
UCKL1
Uniprot ID:
Q9NWZ5
Reactions
Inosine triphosphate + Cytidine unknown IDP + Cytidine monophosphatedetails
Inosine triphosphate + Uridine unknown IDP + Uridine 5'-monophosphatedetails
Gene Name:
ENTPD8
Uniprot ID:
Q5MY95
Reactions
Inosine triphosphate + Water unknown IDP + Phosphoric aciddetails
IDP + Water unknown Inosinic acid + Phosphoric aciddetails
Gene Name:
NME5
Uniprot ID:
P56597
Reactions
Adenosine triphosphate + IDP unknown ADP + Inosine triphosphatedetails