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Human Metabolome Database Version 3.5

Showing metabocard for (2E)-Dodecenoyl-CoA (HMDB03712)

• Identification
• Taxonomy
• Ontology
• Physical properties
• Spectra
• Biological properties
• Concentrations
• Links
• References

enzymes (114) transporters (1)

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Record Information
Version	3.5
Creation Date	2006-08-12 21:47:32 -0600
Update Date	2013-02-08 17:12:44 -0700
HMDB ID	HMDB03712
Secondary Accession Numbers	None
Metabolite Identification
Common Name	(2E)-Dodecenoyl-CoA
Description	(2E)-Dodecenoyl-CoA is an intermediate in fatty acid metabolism, the substrate of the enzyme acyl-CoA oxidase [EC-1.3.3.6], and enzymes acyl-CoA dehydrogenase, long-chain-acyl-CoA dehydrogenase [EC 1.3.99.3-1.3.99.13]; (2E)-Dodecenoyl-CoA is an intermediate in fatty acid elongation in mitochondria, being the substrate of the enzyme enoyl-CoA hydratase and [EC 4.2.1.17]. (KEGG).
Structure	Download: MOL | SDF | SMILES | InChI Display: 2D Structure | 3D Structure
Synonyms	(2E)-Dodec-2-enoyl-CoA (2E)-Dodec-2-enoyl-Coenzyme A 2-trans-Dodecenoyl-CoA 2-trans-Dodecenoyl-Coenzyme A
Chemical Formula	C33H52N7O17P3S
Average Molecular Weight	943.789
Monoisotopic Molecular Weight	943.235323499
IUPAC Name	[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-{[2-({2-[(2E)-dodec-2-enoylsulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}-3-hydroxy-2,2-dimethylpropyl phosphonato]oxy}phosphonate
Traditional IUPAC Name	[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl [(3R)-3-{[2-({2-[(2E)-dodec-2-enoylsulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}-3-hydroxy-2,2-dimethylpropyl phosphonato]oxyphosphonate
CAS Registry Number	1066-12-2
SMILES	CCCCCCCCC\C=C\C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)([O-])OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(=O)([O-])[O-])N1C=NC2=C1N=CN=C2N
InChI Identifier	InChI=1S/C33H56N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-24(42)61-17-16-35-23(41)14-15-36-31(45)28(44)33(2,3)19-54-60(51,52)57-59(49,50)53-18-22-27(56-58(46,47)48)26(43)32(55-22)40-21-39-25-29(34)37-20-38-30(25)40/h12-13,20-22,26-28,32,43-44H,4-11,14-19H2,1-3H3,(H,35,41)(H,36,45)(H,49,50)(H,51,52)(H2,34,37,38)(H2,46,47,48)/p-4/b13-12+/t22-,26-,27-,28+,32-/m1/s1
InChI Key	IRFYVBULXZMEDE-DEEZISNZSA-J
Chemical Taxonomy
Kingdom	Organic Compounds
Super Class	Lipids
Class	Fatty Acid Esters
Sub Class	Acyl CoAs
Other Descriptors	Aromatic Heteropolycyclic Compounds
Substituents	1 Phosphoribosyl Imidazole Aminopyrimidine Carboxamide Group Carboxylic Thioester Coenzyme A Enone Glycosyl Compound Imidazole Imidazopyrimidine Monosaccharide Phosphate N Glycosyl Compound Organic Hypophosphite Organic Phosphite Organic Pyrophosphate Oxolane Pentose Monosaccharide Phosphoric Acid Ester Purine Purine Ribonucleoside Diphosphate Pyrimidine Saccharide Secondary Alcohol Secondary Carboxylic Acid Amide Thiocarboxylic Acid Ester
Direct Parent	Acyl CoAs
Ontology
Status	Expected and Not Quantified
Origin	Endogenous Food
Biofunction	Cell signaling Fuel and energy storage Fuel or energy source Lipid biosynthesis, Fatty acid transport Membrane integrity/stability
Application	Nutrients Stabilizers Surfactants and Emulsifiers
Cellular locations	Extracellular Membrane
Physical Properties
State	Solid
Experimental Properties	Property Value Reference Melting Point Not Available Not Available Boiling Point Not Available Not Available Water Solubility Not Available Not Available LogP 0.519 Not Available
Predicted Properties	Property Value Source Water Solubility 2.56 g/L ALOGPS LogP 2.22 ALOGPS LogP -2 ChemAxon LogS -2.60 ALOGPS pKa (strongest acidic) 0.83 ChemAxon pKa (strongest basic) 4.95 ChemAxon Hydrogen Acceptor Count 17 ChemAxon Hydrogen Donor Count 5 ChemAxon Polar Surface Area 374.95 A2 ChemAxon Rotatable Bond Count 29 ChemAxon Refractivity 214.85 ChemAxon Polarizability 90.8 ChemAxon Formal Charge -4 ChemAxon Physiological Charge -4 ChemAxon
Spectra
	Not Available
Biological Properties
Cellular Locations	Extracellular Membrane
Biofluid Locations	Not Available
Tissue Location	Not Available
Pathways	Name SMPDB Link KEGG Link Fatty Acid Elongation In Mitochondria SMP00054 map00062 Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids SMP00481 Not Available
Normal Concentrations
	Not Available
Abnormal Concentrations
	Not Available
Associated Disorders and Diseases
Disease References	None
Associated OMIM IDs	None
External Links
DrugBank ID	Not Available
Phenol Explorer Compound ID	Not Available
Phenol Explorer Metabolite ID	Not Available
FoodDB ID	FDB023218
KNApSAcK ID	Not Available
Chemspider ID	26330706
KEGG Compound ID	C03221
BioCyc ID	CPD-7222
BiGG ID	41433
Wikipedia Link	Not Available
NuGOwiki Link	HMDB03712
Metagene Link	HMDB03712
METLIN ID	Not Available
PubChem Compound	45266564
PDB ID	Not Available
ChEBI ID	57330
References
Synthesis Reference	Struijk, Cornelia B.; Beerthuis, R. K. The enzymic conversion of 3cis-and 3trans-alkenoyl-CoA esters into their 2trans-isomers. Biochimica et Biophysica Acta, Lipids and Lipid Metabolism (1966), 116(1), 12-22.
Material Safety Data Sheet (MSDS)	Not Available
General References	Not Available

---

Enzymes
Name: 3-ketoacyl-CoA thiolase, mitochondrial Reactions: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA [RN:R00391] Gene Name: ACAA2 Uniprot ID: P42765 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 3-ketoacyl-CoA thiolase, peroxisomal Reactions: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA [RN:R00391] Gene Name: ACAA1 Uniprot ID: P09110 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Trifunctional enzyme subunit beta, mitochondrial Reactions: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA [RN:R00391] Gene Name: HADHB Uniprot ID: P55084 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial Reactions: 2-methyl-3-oxopropanoate + CoA + H2O + NAD+ = propanoyl-CoA + HCO3- + NADH [RN:R00922] Gene Name: ALDH6A1 Uniprot ID: Q02252 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain specific acyl-CoA dehydrogenase, mitochondrial Reactions: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor [RN:R00392] Gene Name: ACADL Uniprot ID: P28330 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Short-chain specific acyl-CoA dehydrogenase, mitochondrial Reactions: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor [RN:R01178] Gene Name: ACADS Uniprot ID: P16219 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Reactions: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor [RN:R00392] Gene Name: ACADM Uniprot ID: P11310 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal acyl-coenzyme A oxidase 1 Reactions: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2 [RN:R00388] Gene Name: ACOX1 Uniprot ID: Q15067 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal acyl-coenzyme A oxidase 2 Reactions: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26- oyl-CoA + reduced acceptor [RN:R07374] Gene Name: ACOX2 Uniprot ID: Q99424 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Isovaleryl-CoA dehydrogenase, mitochondrial Reactions: 3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor [RN:R04096] Gene Name: IVD Uniprot ID: P26440 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal acyl-coenzyme A oxidase 3 Reactions: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2 [RN:R00388] Gene Name: ACOX3 Uniprot ID: O15254 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Glutaryl-CoA dehydrogenase, mitochondrial Reactions: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor [RN:R02488] Gene Name: GCDH Uniprot ID: Q92947 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Hepatic triacylglycerol lipase Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: LIPC Uniprot ID: P11150 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol O-acyltransferase 1 Reactions: acyl-CoA + 1,2-diacyl-sn-glycerol = CoA + triacylglycerol [RN:R02251] Gene Name: DGAT1 Uniprot ID: O75907 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Reactions: 3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine = [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2 [RN:R01701] Gene Name: BCKDHB Uniprot ID: P21953 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial Reactions: 3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine = [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2 [RN:R01701] Gene Name: BCKDHA Uniprot ID: P12694 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA desaturase Reactions: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O [RN:R02222] Gene Name: SCD Uniprot ID: O00767 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal bifunctional enzyme Reactions: (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA [RN:R04100] Gene Name: EHHADH Uniprot ID: Q08426 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Enoyl-CoA hydratase, mitochondrial Reactions: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O [RN:R02685 R07314] Gene Name: ECHS1 Uniprot ID: P30084 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Trifunctional enzyme subunit alpha, mitochondrial Reactions: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O [RN:R02685 R07314] Gene Name: HADHA Uniprot ID: P40939 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Sterol O-acyltransferase 2 Reactions: acyl-CoA + cholesterol = CoA + cholesterol ester [RN:R01461] Gene Name: SOAT2 Uniprot ID: O75908 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Sterol O-acyltransferase 1 Reactions: acyl-CoA + cholesterol = CoA + cholesterol ester [RN:R01461] Gene Name: SOAT1 Uniprot ID: P35610 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Bile acid-CoA:amino acid N-acyltransferase Reactions: palmitoyl-CoA + H2O = CoA + palmitate [RN:R01274] Gene Name: BAAT Uniprot ID: Q14032 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain-fatty-acid--CoA ligase 4 Reactions: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390] Gene Name: ACSL4 Uniprot ID: O60488 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain-fatty-acid--CoA ligase 1 Reactions: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390] Gene Name: ACSL1 Uniprot ID: P33121 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain-fatty-acid--CoA ligase 6 Reactions: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390] Gene Name: ACSL6 Uniprot ID: Q9UKU0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain-fatty-acid--CoA ligase 5 Reactions: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390] Gene Name: ACSL5 Uniprot ID: Q9ULC5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain-fatty-acid--CoA ligase 3 Reactions: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390] Gene Name: ACSL3 Uniprot ID: O95573 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Glycerol-3-phosphate acyltransferase 1, mitochondrial Reactions: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate [RN:R00851] Gene Name: GPAM Uniprot ID: Q9HCL2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Trans-2-enoyl-CoA reductase, mitochondrial Reactions: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+ [RN:R07162] Gene Name: MECR Uniprot ID: Q9BV79 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal trans-2-enoyl-CoA reductase Reactions: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+ [RN:R07162] Gene Name: PECR Uniprot ID: Q9BY49 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cytosolic acyl coenzyme A thioester hydrolase Reactions: palmitoyl-CoA + H2O = CoA + palmitate [RN:R01274] Gene Name: ACOT7 Uniprot ID: O00154 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A thioesterase 2, mitochondrial Reactions: palmitoyl-CoA + H2O = CoA + palmitate [RN:R01274] Gene Name: ACOT2 Uniprot ID: P49753 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A thioesterase 4 Reactions: palmitoyl-CoA + H2O = CoA + palmitate [RN:R01274] Gene Name: ACOT4 Uniprot ID: Q8N9L9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A thioesterase 8 Reactions: choloyl-CoA + H2O = cholate + CoA [RN:R07296] Gene Name: ACOT8 Uniprot ID: O14734 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dihydroxyacetone phosphate acyltransferase Reactions: acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate [RN:R01013] Gene Name: GNPAT Uniprot ID: O15228 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma Reactions: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02241] Gene Name: AGPAT3 Uniprot ID: Q9NRZ7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta Reactions: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02241] Gene Name: AGPAT2 Uniprot ID: O15120 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha Reactions: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02241] Gene Name: AGPAT1 Uniprot ID: Q99943 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Reactions: --- [] Gene Name: ACADSB Uniprot ID: P45954 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Very long-chain acyl-CoA synthetase Reactions: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390] Gene Name: SLC27A2 Uniprot ID: O14975 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisome proliferator-activated receptor gamma Reactions: --- [] Gene Name: PPARG Uniprot ID: P37231 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisome proliferator-activated receptor alpha Reactions: Gene Name: PPARA Uniprot ID: Q07869 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisome proliferator-activated receptor delta Reactions: Gene Name: PPARD Uniprot ID: Q03181 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA-binding protein Reactions: Gene Name: DBI Uniprot ID: P07108 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Fatty acid-binding protein, heart Reactions: Gene Name: FABP3 Uniprot ID: P05413 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon Reactions: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02241] Gene Name: AGPAT5 Uniprot ID: Q9NUQ2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Bile acyl-CoA synthetase Reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA [RN:R02794] (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA [RN:R04580] Gene Name: SLC27A5 Uniprot ID: Q9Y2P5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Reactions: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine [RN:R02662] Gene Name: DBT Uniprot ID: P11182 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 2-acylglycerol O-acyltransferase 2 Reactions: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol [RN:R01368] Gene Name: MOGAT2 Uniprot ID: Q3SYC2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain fatty acid transport protein 3 Reactions: Gene Name: SLC27A3 Uniprot ID: Q5K4L6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA dehydrogenase family member 10 Reactions: Gene Name: ACAD10 Uniprot ID: Q6JQN1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA dehydrogenase family member 11 Reactions: Gene Name: ACAD11 Uniprot ID: Q709F0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Glycerol-3-phosphate acyltransferase 4 Reactions: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate [RN:R00851] Gene Name: AGPAT6 Uniprot ID: Q86UL3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 3,2-trans-enoyl-CoA isomerase, mitochondrial Reactions: (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA [RN:R04100] Gene Name: DCI Uniprot ID: P42126 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A synthetase ACSM1, mitochondrial Reactions: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389] Gene Name: ACSM1 Uniprot ID: Q08AH1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol O-acyltransferase 2 Reactions: acyl-CoA + 1,2-diacyl-sn-glycerol = CoA + triacylglycerol [RN:R02251] Gene Name: DGAT2 Uniprot ID: Q96PD7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-acyl-sn-glycerol-3-phosphate acyltransferase delta Reactions: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02241] Gene Name: AGPAT4 Uniprot ID: Q9NRZ5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 2-acylglycerol O-acyltransferase 1 Reactions: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol [RN:R01368] Gene Name: MOGAT1 Uniprot ID: Q96PD6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Isobutyryl-CoA dehydrogenase, mitochondrial Reactions: Gene Name: ACAD8 Uniprot ID: Q9UKU7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA dehydrogenase family member 9, mitochondrial Reactions: Gene Name: ACAD9 Uniprot ID: Q9H845 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain fatty acid transport protein 4 Reactions: Gene Name: SLC27A4 Uniprot ID: Q6P1M0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Fatty acyl-CoA reductase 1 Reactions: Gene Name: FAR1 Uniprot ID: Q8WVX9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Fatty acyl-CoA reductase 2 Reactions: Gene Name: FAR2 Uniprot ID: Q96K12 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA wax alcohol acyltransferase 1 Reactions: acyl-CoA + a long-chain alcohol = CoA + a long-chain ester [RN:R01999] Gene Name: AWAT1 Uniprot ID: Q58HT5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA wax alcohol acyltransferase 2 Reactions: acyl-CoA + a long-chain alcohol = CoA + a long-chain ester [RN:R01999] Gene Name: AWAT2 Uniprot ID: Q6E213 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol O-acyltransferase 2-like protein 6 Reactions: Gene Name: DGAT2L6 Uniprot ID: Q6ZPD8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Putative diacylglycerol O-acyltransferase 2-like protein 7 Reactions: Gene Name: DGAT2L7 Uniprot ID: Q6IED9 Protein Sequence: FASTA
Name: 2-acylglycerol O-acyltransferase 3 Reactions: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol [RN:R01368] Gene Name: MOGAT3 Uniprot ID: Q86VF5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lysophospholipid acyltransferase 5 Reactions: acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine = CoA + 1,2-diacyl-sn-glycero-3-phosphocholine [RN:R01318] Gene Name: LPCAT3 Uniprot ID: Q6P1A2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lysophosphatidylcholine acyltransferase 1 Reactions: acetyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine [RN:R03437] Gene Name: LPCAT1 Uniprot ID: Q8NF37 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lysocardiolipin acyltransferase 1 Reactions: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02241] Gene Name: LCLAT1 Uniprot ID: Q6UWP7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lysophospholipid acyltransferase LPCAT4 Reactions: Gene Name: LPCAT4 Uniprot ID: Q643R3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Glycerol-3-phosphate acyltransferase 3 Reactions: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate [RN:R00851] Gene Name: AGPAT9 Uniprot ID: Q53EU6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Glycine N-acyltransferase Reactions: acyl-CoA + glycine = CoA + N-acylglycine [RN:R00395] Gene Name: GLYAT Uniprot ID: Q6IB77 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Glycine N-acyltransferase-like protein 1 Reactions: acyl-CoA + glycine = CoA + N-acylglycine [RN:R00395] Gene Name: GLYATL1 Uniprot ID: Q969I3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Glycine N-acyltransferase-like protein 2 Reactions: acyl-CoA + glycine = CoA + N-acylglycine [RN:R00395] Gene Name: GLYATL2 Uniprot ID: Q8WU03 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal 3,2-trans-enoyl-CoA isomerase Reactions: (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA [RN:R04100] Gene Name: PECI Uniprot ID: O75521 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA synthetase family member 4 Reactions: Gene Name: AASDH Uniprot ID: Q4L235 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Very long-chain specific acyl-CoA dehydrogenase, mitochondrial Reactions: Gene Name: ACADVL Uniprot ID: P49748 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A oxidase-like protein Reactions: Gene Name: ACOXL Uniprot ID: Q9NUZ1 Protein Sequence: FASTA
Name: Acyl-coenzyme A synthetase ACSM6, mitochondrial Reactions: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389] Gene Name: ACSM6 Uniprot ID: Q6P461 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A synthetase ACSM2A, mitochondrial Reactions: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389] Gene Name: ACSM2A Uniprot ID: Q08AH3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A synthetase ACSM2B, mitochondrial Reactions: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389] Gene Name: ACSM2B Uniprot ID: Q68CK6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A synthetase ACSM3, mitochondrial Reactions: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389] Gene Name: ACSM3 Uniprot ID: Q53FZ2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A synthetase ACSM5, mitochondrial Reactions: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389] Gene Name: ACSM5 Uniprot ID: Q6NUN0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal coenzyme A diphosphatase NUDT7 Reactions: Gene Name: NUDT7 Uniprot ID: P0C024 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A synthetase ACSM4, mitochondrial Reactions: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00389] Gene Name: ACSM4 Uniprot ID: P0C7M7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Glycerol-3-phosphate acyltransferase 2, mitochondrial Reactions: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate [RN:R00851] Gene Name: GPAT2 Uniprot ID: Q6NUI2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal D3,D2-enoyl-CoA isomerase isoform 1 variant Reactions: Gene Name: Not Available Uniprot ID: Q53GC8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal D3,D2-enoyl-CoA isomerase isoform 1 variant Reactions: Gene Name: Not Available Uniprot ID: Q53HG3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nef-associated protein 1 Reactions: Gene Name: C9orf156 Uniprot ID: Q9BU70 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Peroxisomal D3,D2-enoyl-CoA isomerase isoform 1 variant Reactions: Gene Name: Not Available Uniprot ID: Q59E94 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A thioesterase 9, mitochondrial Reactions: Gene Name: ACOT9 Uniprot ID: Q9Y305 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA synthetase family member 3, mitochondrial Reactions: Gene Name: ACSF3 Uniprot ID: Q4G176 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A thioesterase 1 Reactions: palmitoyl-CoA + H2O = CoA + palmitate [RN:R01274] Gene Name: ACOT1 Uniprot ID: Q86TX2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cytosolic acyl coenzyme A thioester hydrolase-like Reactions: palmitoyl-CoA + H2O = CoA + palmitate [RN:R01274] Gene Name: ACOT7L Uniprot ID: Q6ZUV0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA synthetase family member 2, mitochondrial Reactions: Gene Name: ACSF2 Uniprot ID: Q96CM8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-coenzyme A thioesterase 11 Reactions: Gene Name: ACOT11 Uniprot ID: Q8WXI4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain-fatty-acid--CoA ligase ACSBG2 Reactions: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390] Gene Name: ACSBG2 Uniprot ID: Q5FVE4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Long-chain-fatty-acid--CoA ligase ACSBG1 Reactions: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA [RN:R00390] Gene Name: ACSBG1 Uniprot ID: Q96GR2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Golgi resident protein GCP60 Reactions: Gene Name: ACBD3 Uniprot ID: Q9H3P7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA-binding domain-containing protein 4 Reactions: Gene Name: ACBD4 Uniprot ID: Q8NC06 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA-binding domain-containing protein 5 Reactions: Gene Name: ACBD5 Uniprot ID: Q5T8D3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: ACAD11 protein Reactions: Gene Name: ACAD11 Uniprot ID: Q08AE9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Putative uncharacterized protein HADHA Reactions: Gene Name: HADHA Uniprot ID: Q53T69 Protein Sequence: FASTA Gene Sequence: FASTA
Name: KIAA1996 protein Reactions: Gene Name: KIAA1996 Uniprot ID: Q8NCM9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Benzodiazepine receptor ligand Reactions: Gene Name: BRL Uniprot ID: Q71U42 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Putative uncharacterized protein HADHA Reactions: Gene Name: HADHA Uniprot ID: Q53TA2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA-binding domain-containing protein 6 Reactions: Gene Name: ACBD6 Uniprot ID: Q9BR61 Protein Sequence: FASTA Gene Sequence: FASTA
Name: PECI protein Reactions: Gene Name: PECI Uniprot ID: Q6IBN4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-Coenzyme A binding domain containing 5 Reactions: Gene Name: ACBD5 Uniprot ID: Q5T8E0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA-binding domain-containing protein 7 Reactions: Gene Name: ACBD7 Uniprot ID: Q8N6N7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Fatty acid-binding protein, intestinal Reactions: Gene Name: FABP2 Uniprot ID: P12104 Protein Sequence: FASTA Gene Sequence: FASTA

Transporters
Name: Long-chain fatty acid transport protein 1 Reactions: --- [] Gene Name: SLC27A1 Uniprot ID: Q6PCB7 Protein Sequence: FASTA Gene Sequence: FASTA

This project is supported by Genome Alberta & Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $600 million in funding from the federal government.