| Record Information |
| Version |
3.5 |
| Creation Date |
2006-12-19 14:02:33 -0700 |
| Update Date |
2013-02-08 17:14:16 -0700 |
| HMDB ID |
HMDB05775 |
| Secondary Accession Numbers |
None |
| Metabolite Identification |
| Common Name |
Tetragastrin |
| Description |
Tetragastrin is the C-terminal tetrapeptide of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin. |
| Structure |
Download:
MOL |
SDF |
SMILES |
InChI
Display:
2D Structure |
3D Structure
|
| Synonyms |
- Carbobenzoxy-TRP-met-asp-phe-amide
- Gatratet
- L-Tryptophyl-L-methionyl-L-aspartylphenyl-Alaninamide
|
| Chemical Formula |
C29H36N6O6S |
| Average Molecular Weight |
596.698 |
| Monoisotopic Molecular Weight |
596.241703604 |
| IUPAC Name |
(3S)-3-[(2S)-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]-4-(methylsulfanyl)butanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid |
| Traditional IUPAC Name |
(3S)-3-[(2S)-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]-4-(methylsulfanyl)butanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid |
| CAS Registry Number |
1947-37-1 |
| SMILES |
CSCC[C@H](NC(=O)[C@@H](N)CC1=CNC2=CC=CC=C12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O |
| InChI Identifier |
InChI=1S/C29H36N6O6S/c1-42-12-11-22(33-27(39)20(30)14-18-16-32-21-10-6-5-9-19(18)21)28(40)35-24(15-25(36)37)29(41)34-23(26(31)38)13-17-7-3-2-4-8-17/h2-10,16,20,22-24,32H,11-15,30H2,1H3,(H2,31,38)(H,33,39)(H,34,41)(H,35,40)(H,36,37)/t20-,22-,23-,24-/m0/s1 |
| InChI Key |
RGYLYUZOGHTBRF-BIHRQFPBSA-N |
| Chemical Taxonomy |
| Kingdom |
Organic Compounds |
| Super Class |
Amino Acids, Peptides, and Analogues |
| Class |
Peptides |
| Sub Class |
N/A |
| Other Descriptors |
- Aromatic Heteropolycyclic Compounds
|
| Substituents |
- 1,3 Aminoalcohol
- Amphetamine Or Derivative
- Carboxamide Group
- Carboxylic Acid
- Indole
- N Acyl Alpha Amino Acid
- N Substituted Alpha Amino Acid
- Primary Aliphatic Amine (Alkylamine)
- Primary Carboxylic Acid Amide
- Pyrrole
- Secondary Carboxylic Acid Amide
- Thioether
- Triptan
- Tryptamine
|
| Direct Parent |
Peptides |
| Ontology |
| Status |
Expected and Not Quantified |
| Origin |
|
| Biofunction |
Not Available |
| Application |
Not Available |
| Cellular locations |
Not Available |
| Physical Properties |
| State |
Solid |
| Experimental Properties |
| Property |
Value |
Reference |
| Melting Point |
Not Available |
Not Available |
| Boiling Point |
Not Available |
Not Available |
| Water Solubility |
Not Available |
Not Available |
| LogP |
Not Available |
Not Available |
|
| Predicted Properties |
|
| Spectra |
|
Not Available
|
| Biological Properties |
| Cellular Locations |
Not Available
|
| Biofluid Locations |
Not Available
|
| Tissue Location |
Not Available
|
| Pathways |
Not Available
|
| Normal Concentrations |
|
Not Available |
| Abnormal Concentrations |
|
Not Available |
| Associated Disorders and Diseases |
| Disease References |
None |
| Associated OMIM IDs |
None |
| External Links |
| DrugBank ID |
Not Available |
| Phenol Explorer Compound ID |
Not Available |
| Phenol Explorer Metabolite ID |
Not Available |
| FoodDB ID |
FDB023765 |
| KNApSAcK ID |
Not Available |
| Chemspider ID |
393888  |
| KEGG Compound ID |
Not Available |
| BioCyc ID |
Not Available |
| BiGG ID |
Not Available |
| Wikipedia Link |
Not Available |
| NuGOwiki Link |
HMDB05775  |
| Metagene Link |
HMDB05775  |
| METLIN ID |
Not Available |
| PubChem Compound |
446569  |
| PDB ID |
Not Available |
| ChEBI ID |
298115  |
| References |
| Synthesis Reference |
Hardy, P. M.; Kenner, G. W.; Sheppard, R. C.; MacLeod, J. K.; Morley, J. S. Therapeutical acylated tetrapeptides. (1965), 58 pp. BE 665591 19651217 CAN 64:104706 AN 1966:104706 |
| Material Safety Data Sheet (MSDS) |
Download (PDF)
|
| General References |
Not Available
|