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Human Metabolome Database Version 3.5

Showing metabocard for DG(16:0e/18:0/0:0) (HMDB11146)

• Identification
• Taxonomy
• Ontology
• Physical properties
• Spectra
• Biological properties
• Concentrations
• Links
• References

enzymes (130)

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Record Information
Version	3.5
Creation Date	2008-10-29 08:21:14 -0600
Update Date	2013-02-08 17:25:46 -0700
HMDB ID	HMDB11146
Secondary Accession Numbers	HMDB11184
Metabolite Identification
Common Name	DG(16:0e/18:0/0:0)
Description	2-Octadecanoyl-1-hexadecyl-sn-glycerol is an intermediate in ether lipid metabolism. 2-Octadecanoyl-1-hexadecyl-sn-glycerol is converted from 2-octadecanoyl-1-hexadecyl-sn-glycero-3-phosphate via phosphatidate phosphatase (EC: 3.1.3.4). Ether lipids are lipids in which one or more of the carbon atoms on glycerol is bonded to an alkyl chain via an ether linkage, as opposed to the usual ester linkage. Ether lipids are called plasmalogens (1-O-1'-alkenyl-2-acylglycerophospholipids) if these are glycerol-containing phospholipids with an unsaturated O-(1-alkenyl) (vinyl ether) group at the first position on the glycerol chain. Plasmalogens as well as some 1-O-alkyl lipids are ubiquitous and sometimes major parts of the cell membranes in mammals and anaerobic bacteria. In archaea, ether lipids are the major polar lipids in the cell envelope and their abundance is one of the major characteristics that separate this group of prokaryotes from the bacteria. In these cells, diphytanylglycerolipids or bipolar macrocyclic tetraethers can form covalently linked 'bilayers'.
Structure	Download: MOL | SDF | SMILES | InChI Display: 2D Structure | 3D Structure
Synonyms	2-Octadecanoyl-1-hexadecyl-sn-glycerol DG(O-16:0/18:0/0:0)
Chemical Formula	C37H74O4
Average Molecular Weight	582.9811
Monoisotopic Molecular Weight	582.558710856
IUPAC Name	(2S)-1-(hexadecyloxy)-3-hydroxypropan-2-yl octadecanoate
Traditional IUPAC Name	(2S)-1-(hexadecyloxy)-3-hydroxypropan-2-yl octadecanoate
CAS Registry Number	Not Available
SMILES	[H][C@](CO)(COCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC
InChI Identifier	InChI=1S/C37H74O4/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-37(39)41-36(34-38)35-40-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h36,38H,3-35H2,1-2H3/t36-/m0/s1
InChI Key	ALBMTLREXAADKV-BHVANESWSA-N
Chemical Taxonomy
Kingdom	Organic Compounds
Super Class	Lipids
Class	Glycerolipids
Sub Class	Other Glycerolipids
Other Descriptors	Aliphatic Acyclic Compounds
Substituents	Carboxylic Acid Ester Dialkyl Ether Fatty Acid Ester Primary Alcohol Saccharide Triose Monosaccharide
Direct Parent	Other Glycerolipids
Ontology
Status	Expected and Not Quantified
Origin	Endogenous Food
Biofunction	Cell signaling Fuel and energy storage Fuel or energy source Membrane integrity/stability
Application	Nutrients Stabilizers Surfactants and Emulsifiers
Cellular locations	Extracellular Membrane
Physical Properties
State	Solid
Experimental Properties	Property Value Reference Melting Point Not Available Not Available Boiling Point Not Available Not Available Water Solubility Not Available Not Available LogP Not Available Not Available
Predicted Properties	Property Value Source Water Solubility 1.570E-05 g/L ALOGPS LogP 10.43 ALOGPS LogP 13.27 ChemAxon LogS -7.57 ALOGPS pKa (strongest acidic) 14.58 ChemAxon pKa (strongest basic) -3 ChemAxon Hydrogen Acceptor Count 3 ChemAxon Hydrogen Donor Count 1 ChemAxon Polar Surface Area 55.76 A2 ChemAxon Rotatable Bond Count 36 ChemAxon Refractivity 177.15 ChemAxon Polarizability 79.55 ChemAxon Formal Charge 0 ChemAxon Physiological Charge 0 ChemAxon
Spectra
	Not Available
Biological Properties
Cellular Locations	Extracellular Membrane
Biofluid Locations	Not Available
Tissue Location	Not Available
Pathways	Not Available
Normal Concentrations
	Not Available
Abnormal Concentrations
	Not Available
Associated Disorders and Diseases
Disease References	None
Associated OMIM IDs	None
External Links
DrugBank ID	Not Available
Phenol Explorer Compound ID	Not Available
Phenol Explorer Metabolite ID	Not Available
FoodDB ID	FDB027921
KNApSAcK ID	Not Available
Chemspider ID	18558308
KEGG Compound ID	Not Available
BioCyc ID	Not Available
BiGG ID	Not Available
Wikipedia Link	Not Available
NuGOwiki Link	HMDB11146
Metagene Link	HMDB11146
METLIN ID	Not Available
PubChem Compound	18603089
PDB ID	Not Available
ChEBI ID	Not Available
References
Synthesis Reference	Not Available
Material Safety Data Sheet (MSDS)	Not Available
General References	Not Available

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Enzymes
Name: Diacylglycerol kinase theta Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKQ Uniprot ID: P52824 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pancreatic triacylglycerol lipase Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: PNLIP Uniprot ID: P16233 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCB1 Uniprot ID: Q9NQ66 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCB4 Uniprot ID: Q15147 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCB2 Uniprot ID: Q00722 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol kinase gamma Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKG Uniprot ID: P49619 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Hepatic triacylglycerol lipase Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: LIPC Uniprot ID: P11150 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCB3 Uniprot ID: Q01970 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pancreatic lipase-related protein 1 Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: PNLIPRP1 Uniprot ID: P54315 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCG2 Uniprot ID: P16885 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lipid phosphate phosphohydrolase 2 Reactions: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate [RN:R02239] Gene Name: PPAP2C Uniprot ID: O43688 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Patatin-like phospholipase domain-containing protein 3 Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: PNPLA3 Uniprot ID: Q9NST1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol kinase alpha Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKA Uniprot ID: P23743 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol kinase delta Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKD Uniprot ID: Q16760 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol kinase epsilon Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKE Uniprot ID: P52429 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Gastric triacylglycerol lipase Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: LIPF Uniprot ID: P07098 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lipid phosphate phosphohydrolase 1 Reactions: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate [RN:R02239] Gene Name: PPAP2A Uniprot ID: O14494 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol kinase beta Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKB Uniprot ID: Q9Y6T7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Endothelial lipase Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: LIPG Uniprot ID: Q9Y5X9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol kinase iota Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKI Uniprot ID: O75912 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Bile salt-activated lipase Reactions: a steryl ester + H2O = a sterol + a fatty acid [RN:R02115] Gene Name: CEL Uniprot ID: P19835 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lipid phosphate phosphohydrolase 3 Reactions: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate [RN:R02239] Gene Name: PPAP2B Uniprot ID: O14495 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol O-acyltransferase 1 Reactions: acyl-CoA + 1,2-diacyl-sn-glycerol = CoA + triacylglycerol [RN:R02251] Gene Name: DGAT1 Uniprot ID: O75907 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCG1 Uniprot ID: P19174 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pancreatic lipase-related protein 2 Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: PNLIPRP2 Uniprot ID: P54317 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol kinase zeta Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKZ Uniprot ID: Q13574 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCD1 Uniprot ID: P51178 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lipoprotein lipase Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: LPL Uniprot ID: P06858 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Galactosylceramide sulfotransferase Reactions: 3'-phosphoadenylyl sulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate [RN:R04017 R06279] Gene Name: GAL3ST1 Uniprot ID: Q99999 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Hormone-sensitive lipase Reactions: (1) diacylglycerol + H2O = monoacylglycerol + a carboxylate [RN:R05209] (2) triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] (3) monoacylglycerol + H2O = glycerol + a carboxylate [RN:R07293] Gene Name: LIPE Uniprot ID: Q05469 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Phosphatidate cytidylyltransferase 2 Reactions: CTP + phosphatidate = diphosphate + CDP-diacylglycerol [RN:R01799] Gene Name: CDS2 Uniprot ID: O95674 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Choline-phosphate cytidylyltransferase A Reactions: CTP + choline phosphate = diphosphate + CDP-choline [RN:R01890] Gene Name: PCYT1A Uniprot ID: P49585 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Phosphatidate cytidylyltransferase 1 Reactions: CTP + phosphatidate = diphosphate + CDP-diacylglycerol [RN:R01799] Gene Name: CDS1 Uniprot ID: Q92903 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Phosphatidylcholine:ceramide cholinephosphotransferase 2 Reactions: a ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol [RN:R08969] Gene Name: SGMS2 Uniprot ID: Q8NHU3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: CDP-diacylglycerol--inositol 3-phosphatidyltransferase Reactions: CDP-diacylglycerol + myo-inositol = CMP + phosphatidyl-1D-myo-inositol [RN:R01802] Gene Name: CDIPT Uniprot ID: O14735 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Phosphatidylcholine:ceramide cholinephosphotransferase 1 Reactions: a ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol [RN:R08969] Gene Name: SGMS1 Uniprot ID: Q86VZ5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 2 Reactions: Gene Name: RAPGEF2 Uniprot ID: Q9Y4G8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: RAF proto-oncogene serine/threonine-protein kinase Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: RAF1 Uniprot ID: P04049 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C alpha type Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKCA Uniprot ID: P17252 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Serine/threonine-protein kinase A-Raf Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: ARAF Uniprot ID: P10398 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Citron Rho-interacting kinase Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: CIT Uniprot ID: O14578 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C beta type Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKCB Uniprot ID: P05771 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C zeta type Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKCZ Uniprot ID: Q05513 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C iota type Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKCI Uniprot ID: P41743 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho-associated protein kinase 1 Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: ROCK1 Uniprot ID: Q13464 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Serine/threonine-protein kinase D1 Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKD1 Uniprot ID: Q15139 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C gamma type Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKCG Uniprot ID: P05129 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho-associated protein kinase 2 Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: ROCK2 Uniprot ID: O75116 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C delta type Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKCD Uniprot ID: Q05655 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Serine/threonine-protein kinase D3 Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKD3 Uniprot ID: O94806 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C theta type Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKCQ Uniprot ID: Q04759 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C eta type Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKCH Uniprot ID: P24723 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCH2 Uniprot ID: O75038 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C epsilon type Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKCE Uniprot ID: Q02156 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras association domain-containing protein 1 Reactions: Gene Name: RASSF1 Uniprot ID: Q9NS23 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Serine/threonine-protein kinase B-raf Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: BRAF Uniprot ID: P15056 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Short transient receptor potential channel 3 Reactions: Gene Name: TRPC3 Uniprot ID: Q13507 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cholinephosphotransferase 1 Reactions: CDP-choline + 1,2-diacyl-sn-glycerol = CMP + a phosphatidylcholine [RN:R01321] Gene Name: CHPT1 Uniprot ID: Q8WUD6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 2-acylglycerol O-acyltransferase 2 Reactions: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol [RN:R01368] Gene Name: MOGAT2 Uniprot ID: Q3SYC2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Patatin-like phospholipase domain-containing protein 4 Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: PNPLA4 Uniprot ID: P41247 Protein Sequence: FASTA Gene Sequence: FASTA
Name: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial Reactions: CDP-diacylglycerol + sn-glycerol 3-phosphate = CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate [RN:R01801] Gene Name: PGS1 Uniprot ID: Q32NB8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol kinase eta Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKH Uniprot ID: Q86XP1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCD4 Uniprot ID: Q9BRC7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCH1 Uniprot ID: Q4KWH8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCE1 Uniprot ID: Q9P212 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCD3 Uniprot ID: Q8N3E9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol O-acyltransferase 2 Reactions: acyl-CoA + 1,2-diacyl-sn-glycerol = CoA + triacylglycerol [RN:R02251] Gene Name: DGAT2 Uniprot ID: Q96PD7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 2-acylglycerol O-acyltransferase 1 Reactions: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol [RN:R01368] Gene Name: MOGAT1 Uniprot ID: Q96PD6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA wax alcohol acyltransferase 1 Reactions: acyl-CoA + a long-chain alcohol = CoA + a long-chain ester [RN:R01999] Gene Name: AWAT1 Uniprot ID: Q58HT5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acyl-CoA wax alcohol acyltransferase 2 Reactions: acyl-CoA + a long-chain alcohol = CoA + a long-chain ester [RN:R01999] Gene Name: AWAT2 Uniprot ID: Q6E213 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol O-acyltransferase 2-like protein 6 Reactions: Gene Name: DGAT2L6 Uniprot ID: Q6ZPD8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Putative diacylglycerol O-acyltransferase 2-like protein 7 Reactions: Gene Name: DGAT2L7 Uniprot ID: Q6IED9 Protein Sequence: FASTA
Name: Sn1-specific diacylglycerol lipase alpha Reactions: Gene Name: DAGLA Uniprot ID: Q9Y4D2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Sn1-specific diacylglycerol lipase beta Reactions: Gene Name: DAGLB Uniprot ID: Q8NCG7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 2-acylglycerol O-acyltransferase 3 Reactions: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol [RN:R01368] Gene Name: MOGAT3 Uniprot ID: Q86VF5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Diacylglycerol kinase kappa Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: DGKK Uniprot ID: Q5KSL6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Serine/threonine-protein kinase D2 Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: PRKD2 Uniprot ID: Q9BZL6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Membrane-associated phosphatidylinositol transfer protein 1 Reactions: Gene Name: PITPNM1 Uniprot ID: O00562 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 Reactions: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol Gene Name: PLCZ1 Uniprot ID: Q86YW0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Patatin-like phospholipase domain-containing protein 2 Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: PNPLA2 Uniprot ID: Q96AD5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: A-kinase anchor protein 13 Reactions: Gene Name: AKAP13 Uniprot ID: Q12802 Protein Sequence: FASTA Gene Sequence: FASTA
Name: RAS guanyl-releasing protein 1 Reactions: Gene Name: RASGRP1 Uniprot ID: O95267 Protein Sequence: FASTA Gene Sequence: FASTA
Name: RAS guanyl-releasing protein 2 Reactions: Gene Name: RASGRP2 Uniprot ID: Q7LDG7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Myosin-IXb Reactions: Gene Name: MYO9B Uniprot ID: Q13459 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Short transient receptor potential channel 6 Reactions: Gene Name: TRPC6 Uniprot ID: Q9Y210 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Short transient receptor potential channel 7 Reactions: Gene Name: TRPC7 Uniprot ID: Q9HCX4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein unc-13 homolog A Reactions: Gene Name: UNC13A Uniprot ID: Q9UPW8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein unc-13 homolog B Reactions: Gene Name: UNC13B Uniprot ID: O14795 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein unc-13 homolog C Reactions: Gene Name: UNC13C Uniprot ID: Q8NB66 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 2 Reactions: Gene Name: ARHGEF2 Uniprot ID: Q92974 Protein Sequence: FASTA Gene Sequence: FASTA
Name: RAS guanyl-releasing protein 4 Reactions: Gene Name: RASGRP4 Uniprot ID: Q8TDF6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Serine/threonine-protein kinase MRCK alpha Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: CDC42BPA Uniprot ID: Q5VT25 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Serine/threonine-protein kinase MRCK beta Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: CDC42BPB Uniprot ID: Q9Y5S2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Serine/threonine-protein kinase MRCK gamma Reactions: ATP + a protein = ADP + a phosphoprotein [RN:R00162] Gene Name: CDC42BPG Uniprot ID: Q6DT37 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor VAV3 Reactions: Gene Name: VAV3 Uniprot ID: Q9UKW4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Acylglycerol kinase, mitochondrial Reactions: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate [RN:R02240] Gene Name: AGK Uniprot ID: Q53H12 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pancreatic lipase-related protein 3 Reactions: triacylglycerol + H2O = diacylglycerol + a carboxylate [RN:R01369] Gene Name: PNLIPRP3 Uniprot ID: Q17RR3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: CDC42 binding protein kinase beta (DMPK-like) Reactions: Gene Name: CDC42BPB Uniprot ID: A9JR72 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Kinase suppressor of Ras 2 Reactions: Gene Name: KSR2 Uniprot ID: Q6VAB6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Tensin-like C1 domain-containing phosphatase Reactions: Gene Name: TENC1 Uniprot ID: Q63HR2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein kinase C, alpha variant Reactions: Gene Name: Not Available Uniprot ID: Q59FI5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Kinase suppressor of Ras 1 Reactions: Gene Name: KSR1 Uniprot ID: Q8IVT5 Protein Sequence: FASTA
Name: Protein kinase C, gamma variant Reactions: Gene Name: Not Available Uniprot ID: Q59EZ0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: CDC42-binding protein kinase beta Reactions: Gene Name: CDC42BPA Uniprot ID: Q8IWQ7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: PRKCA protein Reactions: Gene Name: PRKCA Uniprot ID: Q7Z727 Protein Sequence: FASTA Gene Sequence: FASTA
Name: SH3 and cysteine-rich domain-containing protein 3 Reactions: Gene Name: STAC3 Uniprot ID: Q96MF2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GEM-interacting protein Reactions: Gene Name: GMIP Uniprot ID: Q9P107 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Differentially expressed in FDCP 8 homolog Reactions: Gene Name: DEF8 Uniprot ID: Q6ZN54 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho GTPase-activating protein 29 Reactions: Gene Name: ARHGAP29 Uniprot ID: Q52LW3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pleckstrin homology domain-containing family M member 3 Reactions: Gene Name: PLEKHM3 Uniprot ID: Q6ZWE6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Minor histocompatibility protein HA-1 Reactions: Gene Name: HMHA1 Uniprot ID: Q92619 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor VAV2 Reactions: Gene Name: VAV2 Uniprot ID: P52735 Protein Sequence: FASTA Gene Sequence: FASTA
Name: UNC13B variant protein Reactions: Gene Name: UNC13B variant protein Uniprot ID: Q4LE73 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho-guanine nucleotide exchange factor Reactions: Gene Name: RGNEF Uniprot ID: Q8N1W1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pleckstrin homology domain-containing family M member 1 Reactions: Gene Name: PLEKHM1 Uniprot ID: Q9Y4G2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: SH3 and cysteine-rich domain-containing protein 2 Reactions: Gene Name: STAC2 Uniprot ID: Q6ZMT1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Beta-chimaerin Reactions: Gene Name: CHN2 Uniprot ID: P52757 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Gamma-1-syntrophin Reactions: Gene Name: SNTG1 Uniprot ID: Q9NSN8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: N-chimaerin Reactions: Gene Name: CHN1 Uniprot ID: P15882 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Unc-13 homolog B (C. elegans) Reactions: Gene Name: UNC13B Uniprot ID: B1AM27 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Myosin-IXa Reactions: Gene Name: MYO9A Uniprot ID: B2RTY4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras association domain-containing protein 5 Reactions: Gene Name: RASSF5 Uniprot ID: Q8WWW0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: UNC13B protein Reactions: Gene Name: UNC13B Uniprot ID: Q2NKJ5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Aging-associated gene 6 protein Reactions: Gene Name: Not Available Uniprot ID: Q2TSD3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: PDZ domain-containing protein 8 Reactions: Gene Name: PDZD8 Uniprot ID: Q8NEN9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Proto-oncogene vav Reactions: Gene Name: VAV1 Uniprot ID: P15498 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Putative pleckstrin homology domain-containing family M member 1P Reactions: Gene Name: PLEKHM1P Uniprot ID: Q69YJ1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: SH3 and cysteine-rich domain-containing protein Reactions: Gene Name: STAC Uniprot ID: Q99469 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rac GTPase-activating protein 1 Reactions: Gene Name: RACGAP1 Uniprot ID: Q9H0H5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras guanyl-releasing protein 3 Reactions: Gene Name: RASGRP3 Uniprot ID: Q8IV61 Protein Sequence: FASTA Gene Sequence: FASTA

This project is supported by Genome Alberta & Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $600 million in funding from the federal government.