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Record Information
Version4.0
Creation Date2012-09-06 15:16:52 UTC
Update Date2017-09-25 12:23:53 UTC
HMDB IDHMDB0015435
Secondary Accession Numbers
  • HMDB15435
StatusExpected but not Quantified
Metabolite Identification
Common NamePolystyrene sulfonate
DescriptionSodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV. [Wikipedia]
Structure
Thumb
SynonymsNot Available
Chemical FormulaC8H8O3S
Average Molecular Weight184.21
Monoisotopic Molecular Weight184.019415292
IUPAC Name4-ethenylbenzene-1-sulfonic acid
Traditional Nametolevamer
CAS Registry Number28210-41-5
SMILES
OS(=O)(=O)C1=CC=C(C=C)C=C1
InChI Identifier
InChI=1S/C8H8O3S/c1-2-7-3-5-8(6-4-7)12(9,10)11/h2-6H,1H2,(H,9,10,11)
InChI KeyMAGFQRLKWCCTQJ-UHFFFAOYSA-N
Chemical Taxonomy
ClassificationNot classified
Ontology
Disposition
Biological Location:
Biofluid and excreta:
Role
Industrial application:
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water Solubility2.59e-01 g/LNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP-0.78ALOGPS
logP1.89ChemAxon
logS-2.2ALOGPS
pKa (Strongest Acidic)-2.1ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area54.37 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity46.37 m3·mol-1ChemAxon
Polarizability17.68 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
SpectraNot Available
Biological Properties
Cellular LocationsNot Available
Biofluid Locations
  • Blood
  • Urine
Tissue LocationNot Available
PathwaysNot Available
NameSMPDB/PathwhizKEGG
No entries found
Normal Concentrations
BiofluidStatusValueAgeSexConditionReferenceDetails
BloodExpected but not Quantified Not AvailableNot AvailableTaking drug identified by DrugBank entry DB01344 details
UrineExpected but not Quantified Not AvailableNot AvailableTaking drug identified by DrugBank entry DB01344 details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDDB01344
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDNot Available
KNApSAcK IDNot Available
Chemspider IDNot Available
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkPolystyrene_sulfonate
NuGOwiki LinkHMDB0015435
METLIN IDNot Available
PubChem CompoundNot Available
PDB IDNot Available
ChEBI IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available