Human Metabolome Database: Showing Protein A-kinase anchor protein 9 (HMDBP01637)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 metabolite

Identification
HMDB Protein ID	HMDBP01637
Secondary Accession Numbers	6962
Name	A-kinase anchor protein 9
Synonyms	A-kinase anchor protein 350 kDa A-kinase anchor protein 450 kDa AKAP 120-like protein AKAP 350 AKAP 450 AKAP-9 CG-NAP Centrosome- and Golgi-localized PKN-associated protein PRKA9 Protein hyperion Protein kinase A-anchoring protein 9 Protein yotiao hgAKAP 350
Gene Name	AKAP9
Protein Type	Enzyme
Biological Properties
General Function	Cell cycle control, cell division, chromosome partitioning
Specific Function	Binds to type II regulatory subunits of protein kinase A. Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. May be required to maintain the integrity of the Golgi apparatus. Isoform 4 is associated with the N-methyl-D-aspartate receptor and is specifically found in the neuromuscular junction (NMJ) as well as in neuronal synapses, suggesting a role in the organization of postsynaptic specializations
Pathways	Not Available
Reactions	Not Available
GO Classification	Not Available
Cellular Location	Cytoplasm Cytoplasm Golgi apparatus cytoskeleton centrosome
Gene Properties
Chromosome Location	Chromosome:7
Locus	7q21-q22
SNPs	AKAP9
Gene Sequence	>11736 bp ATGGAGGACGAGGAGAGACAGAAGAAGCTGGAGGCCGGCAAAGCCAAGATTGAAGAACTC TCTTTAGCTTTTCTTGTCAGACAGCTTGCCCAGTTTCGACAAAGAAAAGCTCAGTCGGAT GGGCAGAGTCCTTCCAAGAAGCAGAAAAAAAAGAGAAAAACGTCAAGCAGTAAACATGAT GTGTCAGCACACCATGATTTGAATATTGATCAATCACAGTGTAATGAAATGTACATAAAT AGTTCTCAGAGAGTAGAATCAACTGTGATTCCTGAATCTACAATAATGAGAACTCTACAT AGTGGAGAAATAACCAGTCATGAGCAGGGCTTCTCTGTGGAACTGGAAAGTGAAATTTCA ACCACAGCAGATGACTGCAGTTCAGAGGTAAATGGTTGCAGTTTTGTGATGAGAACAGGA AAGCCTACAAATTTATTAAGGGAAGAAGAATTTGGTGTTGATGATTCTTATTCTGAACAA GGAGCACAAGACAGTCCGACTCATCTAGAGATGATGGAAAGTGAGTTGGCTGGGAAGCAG CATGAGATTGAAGAGCTAAACAGAGAGCTGGAAGAAATGAGGGTTACCTATGGGACTGAA GGACTGCAGCAGTTACAAGAATTTGAAGCTGCCATTAAACAAAGAGATGGCATTATAACC CAGCTCACTGCTAATTTACAACAAGCAAGAAGAGAAAAGGATGAGACAATGAGAGAATTT TTAGAGTTGACAGAACAGAGTCAAAAATTACAGATTCAATTTCAGCAATTACAGGCTAGT GAAACTCTGAGAAACAGCACTCATAGTAGCACAGCTGCAGACTTACTACAAGCCAAACAA CAGATCCTCACTCATCAACAGCAGCTTGAAGAACAAGACCACTTATTAGAAGATTATCAG AAAAAGAAAGAAGACTTCACAATGCAAATTAGTTTCTTGCAAGAGAAAATTAAAGTATAT GAAATGGAACAAGATAAAAAAGTAGAAAACTCAAATAAAGAAGAAATACAGGAAAAGGAG ACAATCATTGAAGAATTAAACACAAAAATAATAGAAGAAGAAAAGAAAACTCTTGAGCTA AAGGATAAATTAACAACTGCTGATAAATTACTAGGAGAATTACAAGAACAGATTGTGCAA AAGAACCAAGAAATAAAAAACATGAAATTAGAGCTGACTAATTCTAAGCAAAAAGAAAGA CAGTCTTCTGAAGAAATAAAACAGTTAATGGGGACAGTCGAAGAACTTCAGAAGAGAAAT CATAAAGACAGCCAGTTCGAAACTGATATAGTACAACGAATGGAACAAGAAACACAAAGA AAGTTAGAACAACTCCGGGCAGAGCTGGATGAGATGTATGGGCAGCAGATAGTGCAAATG AAACAAGAATTAATAAGACAACACATGGCACAGATGGAGGAAATGAAAACACGGCATAAG GGAGAAATGGAGAATGCTTTAAGGTCATATTCAAATATTACAGTTAATGAAGATCAGATA AAGTTAATGAATGTGGCAATAAATGAACTGAATATAAAATTGCAAGATACTAACTCTCAA AAGGAAAAACTCAAGGAAGAACTAGGACTAATTTTAGAAGAAAAGTGTGCTCTACAGAGA CAGCTTGAAGACCTTGTTGAAGAATTGAGCTTTTCAAGGGAACAGATTCAGAGAGCTAGA CAGACAATAGCTGAACAAGAAAGTAAACTTAATGAAGCACATAAGTCCCTTAGTACAGTG GAAGATTTGAAAGCTGAGATTGTTTCTGCATCTGAATCCAGAAAGGAACTAGAATTAAAA CATGAAGCAGAAGTTACAAATTACAAGATAAAACTTGAAATGTTAGAAAAAGAAAAGAAT GCTGTGTTAGACAGAATGGCTGAATCACAAGAAGCTGAATTAGAGAGGCTGAGAACACAG CTTCTATTTAGTCACGAAGAAGAGCTTTCCAAACTGAAGGAAGATTTAGAAATTGAACAT CGAATAAATATTGAAAAACTTAAAGATAATTTAGGCATTCACTATAAACAGCAGATAGAT GGTTTACAGAATGAAATGAGTCAAAAGATAGAAACCATGCAGTTTGAAAAGGACAATTTG ATAACTAAGCAGAATCAATTAATTTTGGAAATTTCAAAGCTAAAAGATTTACAGCAGTCT CTTGTAAATTCAAAGTCAGAAGAAATGACTCTTCAAATCAATGAACTTCAAAAAGAAATT GAAATACTCAGACAAGAAGAAAAAGAAAAGGGTACACTTGAACAAGAAGTTCAAGAATTA CAACTTAAAACAGAATTGTTAGAAAAACAGATGAAGGAAAAAGAGAATGATCTTCAAGAA AAATTTGCACAACTTGAAGCAGAGAATAGCATTCTTAAAGATGAAAAGAAAACCCTTGAA GACATGTTGAAAATACATACTCCTGTTAGCCAAGAAGAAAGATTGATTTTCTTAGACTCC ATTAAGTCCAAATCCAAAGACTCTGTGTGGGAAAAAGAAATAGAAATACTTATAGAGGAA AATGAGGACCTCAAACAACAATGTATTCAGCTAAATGAAGAGATTGAAAAGCAAAGGAAC ACTTTTTCATTTGCTGAAAAAAACTTTGAAGTTAACTATCAAGAGTTACAAGAGGAGTAT GCTTGCCTTCTCAAAGTAAAAGATGATTTAGAAGACAGTAAAAATAAACAGGAATTAGAG TATAAAAGTAAACTTAAAGCACTTAATGAAGAGCTTCATTTGCAAAGAATAAATCCAACT ACAGTGAAAATGAAAAGTTCTGTCTTTGATGAAGACAAAACTTTTGTAGCAGAAACATTG GAAATGGGTGAGGTTGTTGAAAAGGATACAACAGAACTCATGGAAAAACTTGAGGTAACC AAGCGAGAGAAATTAGAGCTGTCACAGAGACTGTCTGATCTTTCTGAACAATTGAAACAG AAACATGGTGAGATTAGTTTTCTAAATGAAGAAGTTAAATCTTTAAAGCAAGAGAAAGAA CAAGTTTCATTGAGATGTAGAGAGCTAGAAATCATTATTAACCACAACAGGGCAGAAAAT GTACAGTCATGTGATACTCAAGTAAGCTCTTTATTAGATGGAGTTGTGACCATGACAAGC AGGGGTGCTGAAGGATCAGTTTCTAAAGTAAATAAAAGTTTTGGTGAAGAATCAAAAATA ATGGTGGAAGATAAAGTTTCTTTTGAAAATATGACTGTTGGAGAAGAAAGTAAGCAAGAA CAGTTGATTTTGGATCACTTACCATCTGTAACAAAGGAATCATCACTTAGAGCAACTCAA CCAAGTGAAAATGATAAACTTCAGAAAGAACTCAATGTACTTAAATCAGAACAGAATGAT TTAAGGCTACAGATGGAAGCCCAACGCATTTGCCTCTCTCTGGTTTATTCAACTCATGTG GATCAGGTTCGTGAATATATGGAAAATGAAAAAGATAAAGCTCTTTGCAGTCTTAAAGAA GAGCTTATTTTTGCTCAAGAGGAAAAGATCAAGGAACTTCAGAAAATACACCAGTTAGAA CTACAGACTATGAAAACACAAGAAACAGGTGATGAAGGAAAGCCTTTACATCTGCTCATT GGAAAACTTCAAAAGGCAGTGTCTGAAGAATGTTCTTATTTTTTACAGACTTTATGCAGT GTCCTTGGTGAATATTATACTCCTGCTTTAAAATGTGAAGTAAATGCAGAAGACAAAGAG AATTCTGGTGATTACATTTCTGAAAATGAAGATCCAGAATTACAAGATTATAGATATGAA GTTCAAGACTTTCAAGAAAATATGCACACTCTTCTCAACAAAGTAACAGAAGAATACAAC AAACTCTTGGTACTTCAAACACGACTAAGCAAGATCTGGGGACAGCAGACAGATGGTATG AAACTTGAATTTGGAGAAGAAAACCTTCCAAAAGAGGAAACAGAGTTTTTATCAATCCAT TCTCAGATGACCAATTTGGAAGACATTGATGTCAATCATAAAAGCAAGTTATCTTCTCTG CAAGATCTTGAAAAAACTAAACTTGAAGAACAAGTTCAAGAATTAGAAAGCCTCATATCC TCTTTGCAGCAACAGTTGAAAGAAACTGAACAAAACTATGAGGCAGAGATCCACTGTTTA CAGAAGAGGCTTCAAGCTGTTAGTGAGTCCACGGTTCCGCCAAGCTTACCTGTTGATTCG GTGGTAATTACAGAATCTGATGCACAGAGAACAATGTACCCTGGAAGTTGTGTGAAAAAG AATATTGATGGTACAATAGAGTTTTCTGGTGAATTTGGAGTGAAAGAGGAAACAAATATC GTTAAGTTGCTTGAAAAACAATACCAAGAACAATTAGAAGAAGAAGTAGCTAAGGTTATT GTGTCAATGAGTATAGCATTTGCTCAACAAACTGAACTGTCTAGAATATCTGGGGGAAAA GAAAATACTGCATCATCAAAGCAAGCACATGCTGTGTGTCAGCAAGAACAACATTATTTT AATGAAATGAAATTATCACAGGATCAAATTGGTTTTCAGACTTTTGAGACAGTGGATGTG AAATTTAAAGAAGAATTTAAACCACTTAGTAAAGAGTTAGGAGAACATGGAAAGGAAATT TTATTATCAAATAGTGATCCCCATGATATACCAGAATCAAAGGACTGTGTGCTGACTATT TCAGAAGAAATGTTCTCCAAAGATAAAACATTTATAGTTAGACAGTCTATTCATGATGAG ATTTCAGTGTCAAGCATGGATGCTTCTAGACAACTAATGTTGAATGAAGAACAGTTGGAA GATATGAGACAGGAACTTGTACGACAATACCAAGAACATCAACAGGCAACGGAATTGTTA AGGCAAGCACATATGCGGCAAATGGAGAGACAGCGAGAAGACCAGGAACAGCTACAAGAA GAGATTAAGAGACTTAATAGACAATTAGCCCAGAGATCCTCCATAGATAATGAAAACCTG GTTTCAGAGAGAGAGAGGGTGCTTTTAGAGGAGCTGGAAGCACTAAAGCAGCTGTCTTTA GCTGGAAGAGAGAAGCTGTGTTGTGAGCTGCGCAACAGCAGTACGCAAACACAGAATGGA AATGAAAACCAAGGAGAAGTTGAAGAACAAACATTTAAAGAAAAGGAATTAGACAGAAAA CCTGAAGATGTGCCTCCTGAGATTTTGTCTAATGAAAGGTATGCACTCCAGAAAGCTAAT AATAGACTTTTGAAGATCCTCTTAGAAGTTGTAAAGACAACAGCAGCTGTTGAAGAAACA ATTGGTCGCCATGTCCTTGGGATTCTAGATAGATCTAGTAAAAGCCAGTCATCTGCCAGC CTAATTTGGAGGTCAGAAGCAGAGGCATCTGTAAAGTCATGTGTCCATGAGGAACATACA AGAGTTACAGATGAATCCATTCCCTCTTATTCTGGAAGTGATATGCCAAGAAATGACATT AACATGTGGTCAAAAGTAACTGAGGAAGGAACAGAGCTGTCACAACGACTTGTGAGGAGT GGTTTTGCTGGAACTGAAATAGACCCTGAAAATGAAGAACTTATGCTGAACATTAGCTCT CGACTACAAGCAGCAGTTGAAAAACTCCTAGAAGCCATAAGTGAAACTAGCAGTCAGCTT GAACATGCGAAAGTGACACAGACAGAGTTGATGCGTGAGTCATTTAGACAGAAACAAGAA GCAACAGAGTCCCTTAAGTGCCAAGAGGAACTTCGAGAGCGCCTTCATGAGGAGTCCAGG GCCAGAGAACAGCTAGCTGTGGAGCTCAGTAAGGCTGAGGGCGTCATTGATGGCTATGCA GATGAAAAAACTCTTTTTGAAAGGCAAATTCAGGAAAAAACTGATATAATAGATCGTCTT GAGCAGGAGTTGTTATGTGCAAGTAACAGGTTGCAAGAATTGGAGGCAGAGCAACAGCAG ATCCAAGAAGAAAGAGAATTACTGTCCAGACAAAAGGAAGCTATGAAAGCAGAGGCAGGC CCAGTTGAACAACAATTACTACAGGAGACAGAAAAATTAATGAAGGAAAAACTAGAAGTA CAATGTCAAGCTGAAAAAGTACGTGATGACCTTCAAAAACAAGTGAAAGCTCTAGAAATA GATGTGGAAGAACAAGTCAGTAGGTTTATAGAGCTGGAACAAGAAAAAAATACTGAACTA ATGGATTTAAGACAGCAAAACCAAGCATTGGAAAAGCAGTTAGAAAAAATGAGAAAATTT TTAGATGAGCAAGCCATTGACAGAGAACATGAGAGAGATGTATTCCAACAGGAAATACAG AAACTAGAACAGCAACTTAAGGTTGTTCCTCGATTCCAGCCTATCAGTGAACATCAAACT AGAGAGGTTGAACAGTTAGCAAATCATCTGAAAGAAAAAACAGACAAATGCAGTGAGCTT TTGCTCTCTAAAGAGCAGCTTCAAAGGGATATACAAGAAAGGAATGAAGAAATAGAGAAA CTGGAGTTCAGAGTAAGAGAACTGGAGCAGGCGCTTCTTGTGAGTGCAGATACTTTTCAA AAGGTAGAGGACCGAAAACACTTTGGAGCTGTAGAAGCTAAACCAGAATTGTCCCTAGAA GTACAATTGCAGGCTGAACGAGATGCCATAGACAGAAAGGAAAAAGAGATTACAAACTTA GAAGAGCAATTAGAACAGTTTAGAGAAGAACTGGAAAATAAGAATGAAGAAGTTCAACAA TTACATATGCAATTAGAAATACAGAAAAAGGAATCTACTACCCGCCTACAAGAACTTGAA CAGGAAAACAAATTATTTAAGGATGACATGGAGAAACTGGGACTTGCCATAAAGGAATCT GATGCCATGTCTACTCAAGACCAACATGTGCTATTTGGGAAATTTGCTCAAATAATACAG GAAAAAGAGGTAGAAATTGACCAATTAAATGAACAAGTTACGAAACTCCAGCAGCAACTT AAAATTACAACAGATAACAAGGTTATTGAAGAAAAAAATGAACTGATAAGGGATCTTGAA ACCCAAATAGAATGTTTGATGAGTGATCAAGAATGTGTGAAGAGAAATAGAGAAGAAGAA ATAGAGCAGCTCAATGAAGTGATTGAAAAACTTCAACAGGAATTGGCAAATATTGGACAG AAGACATCAATGAATGCTCATTCCCTCTCAGAAGAAGCAGACAGTTTAAAACATCAATTG GATGTGGTTATAGCTGAAAAGCTGGCCTTGGAACAGCAAGTAGAAACCGCTAATGAAGAA ATGACCTTCATGAAAAATGTACTTAAAGAAACCAATTTTAAAATGAATCAGCTAACACAG GAATTATTCAGCTTAAAGAGAGAACGTGAAAGTGTGGAAAAGATTCAAAGCATACCAGAG AATAGTGTTAACGTGGCTATAGATCATCTGAGCAAAGACAAACCTGAACTAGAAGTAGTC CTTACAGAGGATGCTCTTAAATCCCTAGAAAATCAGACATACTTCAAATCTTTTGAAGAA AATGGCAAAGGTTCCATAATTAATTTGGAAACAAGGTTGCTACAACTTGAGAGCACTGTT AGTGCAAAGGACTTAGAACTTACCCAGTGTTATAAACAAATAAAAGACATGCAAGAACAA GGCCAGTTTGAAACAGAAATGCTTCAAAAGAAGATTGTAAACCTACAGAAAATAGTTGAA GAAAAAGTGGCTGCTGCTCTTGTCAGTCAAATCCAACTTGAGGCAGTTCAGGAATATGCA AAATTCTGTCAAGATAATCAAACAATTTCATCAGAACCTGAAAGAACAAATATTCAGAAT TTAAATCAACTAAGAGAAGATGAGTTGGGGTCAGATATATCAGCATTAACCTTGAGAATA TCAGAATTAGAAAGCCAGGTTGTTGAAATGCATACTAGTTTGATTTTAGAAAAAGAACAA GTAGAAATTGCAGAAAAAAATGTTTTAGAAAAAGAAAAGAAGCTGCTAGAACTACAGAAG CTATTGGAGGGCAATGAGAAAAAACAGAGAGAGAAAGAAAAGAAAAGAAGCCCTCAAGAT GTTGAAGTTCTCAAGACAACTACTGAGCTATTTCATAGCAATGAAGAAAGTGGATTTTTT AATGAACTCGAGGCTCTTAGAGCTGAATCAGTGGCTACCAAAGCAGAACTTGCCAGTTAT AAAGAAAAGGCTGAAAAACTTCAAGAAGAGCTTTTGGTAAAAGAAACAAATATGACATCT CTTCAGAAAGACTTAAGCCAAGTTAGGGATCACCTCGCAGAGGCAAAAGAGAAATTGTCC ATTTTAGAAAAAGAAGATGAGACTGAGGTACAAGAAAGCAAAAAGGCCTGCATGTTTGAG CCACTTCCTATAAAACTGAGTAAGAGCATTGCATCCCAGACAGATGGGACTCTGAAGATC AGTAGCAGCAATCAGACTCCACAAATTCTTGTTAAAAATGCAGGAATACAAATTAATTTA CAGAGTGAATGTTCCTCAGAAGAAGTTACTGAAATAATCAGTCAGTTTACTGAAAAAATT GAGAAGATGCAAGAACTACATGCTGCTGAAATTTTGGACATGGAATCCAGACATATTTCA GAAACTGAAACCTTAAAGAGGGAACACTATGTTGCCGTTCAGTTACTGAAAGAGGAATGT GGTACCTTGAAGGCAGTGATACAGTGTCTGAGAAGTAAAGAGGTATTTGGTTTTTATAAT ATGTGTTTTTCAACATTGTGTGATTCTGGATCAGACTGGGGTCAGGGAATTTATCTTACA CACAGTCAGGGATTTGACATAGCATCAGAAGGCCGAGGAGAAGAAAGTGAAAGTGCAACA GATTCCTTTCCAAAGAAAATAAAGGGATTACTGAGAGCTGTCCATAATGAAGGCATGCAG GTGCTTTCTCTCACTGAGTCTCCCTATAGTGATGGAGAGGACCATTCTATTCAGCAGGTT TCAGAACCTTGGCTAGAAGAGAGAAAAGCTTACATCAATACAATCTCATCTCTAAAGGAT TTAATTACAAAGATGCAACTGCAAAGAGAAGCCGAGGTTTATGATAGTTCTCAATCTCAT GAGAGCTTCTCAGACTGGCGAGGTGAACTACTGCTTGCCCTTCAACAAGTTTTCTTAGAA GAGCGTAGTGTTTTACTAGCAGCATTTCGGACGGAGCTGACAGCTCTAGGTACTACAGAT GCAGTTGGTTTACTAAACTGTTTGGAACAGAGAATACAAGAACAGGGTGTTGAATATCAA GCAGCTATGGAATGCCTCCAGAAAGCAGATAGAAGGAGTTTGTTATCTGAAATTCAGGCA CTGCATGCACAAATGAATGGTAGGAAAATTACTCTGAAAAGAGAACAAGAGAGTGAGAAA CCAAGCCAAGAACTCTTGGAATATAATATACAGCAGAAGCAGTCTCAAATGCTGGAGATG CAAGTGGAGCTCAGCAGTATGAAAGACAGAGCAACGGAACTGCAGGAGCAGCTGAGTTCT GAGAAAATGGTGGTTGCTGAACTGAAGAGTGAGCTTGCACAAACTAAATTGGAACTAGAA ACAACACTCAAGGCACAGCATAAACACCTAAAAGAATTGGAGGCTTTCAGGTTGGAAGTT AAAGATAAGACAGATGAAGTACATTTGCTTAATGACACATTAGCAAGTGAACAGAAAAAA TCAAGAGAGCTCCAGTGGGCTTTGGAGAAAGAGAAAGCCAAGTTGGGACGCAGTGAAGAA CGGGATAAAGAAGAACTTGAGGATCTGAAGTTTTCACTTGAGAGTCAGAAACAAAGGAAT CTTCAGCTAAATCTACTTTTGGAACAACAGAAACAACTACTGAACGAATCCCAGCAAAAA ATAGAATCACAGAGAATGCTATATGATGCCCAGTTGTCAGAAGAACAAGGTCGAAACTTA GAGCTTCAGGTACTTCTTGAATCTGAGAAAGTTCGAATTCGGGAAATGAGTAGTACCCTA GATAGGGAGCGGGAATTGCACGCACAGCTGCAGAGCAGTGATGGTACTGGACAGTCTCGG CCACCCTTGCCCTCAGAGGACCTACTGAAAGAGCTGCAGAAACAGCTAGAGGAAAAACAC AGTCGCATAGTAGAATTGTTAAATGAGACTGAAAAATATAAACTGGATTCTTTGCAAACA CGACAGCAAATGGAAAAAGATAGGCAGGTTCACAGGAAAACACTGCAGACAGAACAGGAG GCCAACACTGAGGGACAGAAAAAAATGCATGAGCTCCAGTCCAAAGTGGAAGATCTTCAG CGCCAGCTGGAAGAGAAAAGACAACAAGTTTATAAGTTAGACCTTGAAGGACAGCGACTA CAAGGAATCATGCAGGAATTCCAGAAGCAAGAACTAGAACGAGAAGAAAAACGAGAAAGT AGAAGAATTCTGTATCAGAACCTTAATGAGCCAACCACGTGGAGCTTAACCAGTGATAGA ACTAGAAATTGGGTTCTTCAACAGAAAATAGAAGGAGAAACAAAAGAATCAAACTACGCT AAATTGATTGAAATGAATGGAGGAGGAACCGGCTGTAATCATGAATTAGAAATGATCAGA CAAAAGCTTCAATGTGTAGCTTCAAAACTACAGGTTCTACCCCAGAAAGCCTCTGAGAGA CTACAGTTTGAAACAGCAGATGATGAAGATTTCATTTGGGTTCAGGAAAATATTGATGAA ATTATTTTACAACTACAGAAATTAACTGGCCAGCAAGGTGAAGAGCCCAGCTTGGTGTCC CCAAGTACTTCTTGTGGCTCATTGACTGAAAGACTACTGAGACAAAATGCTGAGCTGACA GGGCATATCAGTCAACTGACTGAAGAGAAGAATGACTTAAGGAACATGGTTATGAAGCTG GAAGAGCAGATCAGGTGGTATCGACAGACAGGAGCTGGTAGAGATAATTCTTCCAGGTTT TCATTGAATGGTGGTGCCAACATTGAAGCCATCATTGCCTCTGAAAAAGAAGTATGGAAC AGAGAAAAATTGACTCTCCAGAAATCTTTGAAAAGGGCAGAGGCTGAAGTATACAAACTG AAAGCTGAACTAAGAAATGACTCTTTACTTCAAACTCTGAGCCCTGATTCTGAACATGTC ACTTTAAAGAGAATTTATGGTAAATACTTGAGGGCAGAAAGTTTTCGAAAGGCTCTCATT TACCAGAAGAAATACCTGCTGCTGTTACTGGGTGGGTTCCAGGAATGTGAAGATGCCACC TTGGCCCTGCTTGCCCGGATGGGGGGGCAGCCAGCTTTCACGGATCTAGAGGTGATCACC AATCGCCCAAAGGGCTTCACCAGGTTTCGGTCGGCCGTCAGAGTATCCATTGCAATTTCC AGAATGAAATTTTTGGTTCGACGGTGGCATCGAGTCACAGGTTCTGTTTCCATCAATATT AACAGAGATGGCTTTGGACTGAATCAAGGTGCAGAAAAGACTGACTCATTTTATCATTCT TCTGGTGGGCTGGAGTTATATGGAGAACCAAGACATACTACGTATCGCTCAAGATCAGAT CTGGACTATATTAGGTCCCCTTTACCATTTCAGAATAGGTACCCAGGCACTCCAGCTGAT TTCAATCCTGGTTCTTTAGCATGTTCTCAGCTTCAGAATTACGATCCTGACAGAGCCCTA ACAGATTATATCACTCGGCTAGAGGCACTGCAAAGACGACTTGGAACTATACAGTCAGGT TCAACTACTCAATTTCATGCTGGCATGAGAAGATAA
Protein Properties
Number of Residues	3911
Molecular Weight	453664.2
Theoretical pI	4.65
Pfam Domain Function	PACT_coil_coil (PF10495 )
Signals	None
Transmembrane Regions	None
Protein Sequence	>A-kinase anchor protein 9 MEDEERQKKLEAGKAKIEELSLAFLVRQLAQFRQRKAQSDGQSPSKKQKKKRKTSSSKHD VSAHHDLNIDQSQCNEMYINSSQRVESTVIPESTIMRTLHSGEITSHEQGFSVELESEIS TTADDCSSEVNGCSFVMRTGKPTNLLREEEFGVDDSYSEQGAQDSPTHLEMMESELAGKQ HEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREF LELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQ KKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLEL KDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRN HKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHK GEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQR QLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELK HEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEH RINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQS LVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQE KFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEE NEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELE YKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVT KREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAEN VQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQE QLILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDLRLQMEAQRICLSLVYSTHV DQVREYMENEKDKALCSLKEELIFAQEEKIKELQKIHQLELQTMKTQETGDEGKPLHLLI GKLQKAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKENSGDYISENEDPELQDYRYE VQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIH SQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAEIHCL QKRLQAVSESTVPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEETNI VKLLEKQYQEQLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYF NEMKLSQDQIGFQTFETVDVKFKEEFKPLSKELGEHGKEILLSNSDPHDIPESKDCVLTI SEEMFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELL RQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSL AGREKLCCELRNSSTQTQNGNENQGEVEEQTFKEKELDRKPEDVPPEILSNERYALQKAN NRLLKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHT RVTDESIPSYSGSDMPRNDINMWSKVTEEGTELSQRLVRSGFAGTEIDPENEELMLNISS RLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESR AREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQ IQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEI DVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ KLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEK LEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNL EEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKES DAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLE TQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQL DVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPE NSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTV SAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYA KFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQ VEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFF NELEALRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLS ILEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINL QSECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLKREHYVAVQLLKEEC GTLKAVIQCLRSKEVFGFYNMCFSTLCDSGSDWGQGIYLTHSQGFDIASEGRGEESESAT DSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINTISSLKD LITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTALGTTD AVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESEK PSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELE TTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEE RDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNL ELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKH SRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQ RQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDR TRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASER LQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSPSTSCGSLTERLLRQNAELT GHISQLTEEKNDLRNMVMKLEEQIRWYRQTGAGRDNSSRFSLNGGANIEAIIASEKEVWN REKLTLQKSLKRAEAEVYKLKAELRNDSLLQTLSPDSEHVTLKRIYGKYLRAESFRKALI YQKKYLLLLLGGFQECEDATLALLARMGGQPAFTDLEVITNRPKGFTRFRSAVRVSIAIS RMKFLVRRWHRVTGSVSININRDGFGLNQGAEKTDSFYHSSGGLELYGEPRHTTYRSRSD LDYIRSPLPFQNRYPGTPADFNPGSLACSQLQNYDPDRALTDYITRLEALQRRLGTIQSG STTQFHAGMRR
External Links
GenBank ID Protein	4128008
UniProtKB/Swiss-Prot ID	Q99996
UniProtKB/Swiss-Prot Entry Name	AKAP9_HUMAN
PDB IDs	Not Available
GenBank Gene ID	AJ010770
GeneCard ID	AKAP9
GenAtlas ID	AKAP9
HGNC ID	HGNC:379
References
General References	Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. Sci Signal. 2009 Aug 18;2(84):ra46. doi: 10.1126/scisignal.2000007. [PubMed:19690332 ] Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science. 2007 May 25;316(5828):1160-6. [PubMed:17525332 ] Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE: The consensus coding sequences of human breast and colorectal cancers. Science. 2006 Oct 13;314(5797):268-74. Epub 2006 Sep 7. [PubMed:16959974 ] Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K, Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R, Zhang J, Hudek AK, Li M, Haddad M, Duggan GE, Fernandez BA, Kanematsu E, Gentles S, Christopoulos CC, Choufani S, Kwasnicka D, Zheng XH, Lai Z, Nusskern D, Zhang Q, Gu Z, Lu F, Zeesman S, Nowaczyk MJ, Teshima I, Chitayat D, Shuman C, Weksberg R, Zackai EH, Grebe TA, Cox SR, Kirkpatrick SJ, Rahman N, Friedman JM, Heng HH, Pelicci PG, Lo-Coco F, Belloni E, Shaffer LG, Pober B, Morton CC, Gusella JF, Bruns GA, Korf BR, Quade BJ, Ligon AH, Ferguson H, Higgins AW, Leach NT, Herrick SR, Lemyre E, Farra CG, Kim HG, Summers AM, Gripp KW, Roberts W, Szatmari P, Winsor EJ, Grzeschik KH, Teebi A, Minassian BA, Kere J, Armengol L, Pujana MA, Estivill X, Wilson MD, Koop BF, Tosi S, Moore GE, Boright AP, Zlotorynski E, Kerem B, Kroisel PM, Petek E, Oscier DG, Mould SJ, Dohner H, Dohner K, Rommens JM, Vincent JB, Venter JC, Li PW, Mural RJ, Adams MD, Tsui LC: Human chromosome 7: DNA sequence and biology. Science. 2003 May 2;300(5620):767-72. Epub 2003 Apr 10. [PubMed:12690205 ] Hillier LW, Fulton RS, Fulton LA, Graves TA, Pepin KH, Wagner-McPherson C, Layman D, Maas J, Jaeger S, Walker R, Wylie K, Sekhon M, Becker MC, O'Laughlin MD, Schaller ME, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Cordes M, Du H, Sun H, Edwards J, Bradshaw-Cordum H, Ali J, Andrews S, Isak A, Vanbrunt A, Nguyen C, Du F, Lamar B, Courtney L, Kalicki J, Ozersky P, Bielicki L, Scott K, Holmes A, Harkins R, Harris A, Strong CM, Hou S, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Leonard S, Rohlfing T, Rock SM, Tin-Wollam AM, Abbott A, Minx P, Maupin R, Strowmatt C, Latreille P, Miller N, Johnson D, Murray J, Woessner JP, Wendl MC, Yang SP, Schultz BR, Wallis JW, Spieth J, Bieri TA, Nelson JO, Berkowicz N, Wohldmann PE, Cook LL, Hickenbotham MT, Eldred J, Williams D, Bedell JA, Mardis ER, Clifton SW, Chissoe SL, Marra MA, Raymond C, Haugen E, Gillett W, Zhou Y, James R, Phelps K, Iadanoto S, Bubb K, Simms E, Levy R, Clendenning J, Kaul R, Kent WJ, Furey TS, Baertsch RA, Brent MR, Keibler E, Flicek P, Bork P, Suyama M, Bailey JA, Portnoy ME, Torrents D, Chinwalla AT, Gish WR, Eddy SR, McPherson JD, Olson MV, Eichler EE, Green ED, Waterston RH, Wilson RK: The DNA sequence of human chromosome 7. Nature. 2003 Jul 10;424(6945):157-64. [PubMed:12853948 ] Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 1998 Oct 30;5(5):277-86. [PubMed:9872452 ] Lin JW, Wyszynski M, Madhavan R, Sealock R, Kim JU, Sheng M: Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1. J Neurosci. 1998 Mar 15;18(6):2017-27. [PubMed:9482789 ] Witczak O, Skalhegg BS, Keryer G, Bornens M, Tasken K, Jahnsen T, Orstavik S: Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450. EMBO J. 1999 Apr 1;18(7):1858-68. [PubMed:10202149 ] Takahashi M, Shibata H, Shimakawa M, Miyamoto M, Mukai H, Ono Y: Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus. J Biol Chem. 1999 Jun 11;274(24):17267-74. [PubMed:10358086 ] Schmidt PH, Dransfield DT, Claudio JO, Hawley RG, Trotter KW, Milgram SL, Goldenring JR: AKAP350, a multiply spliced protein kinase A-anchoring protein associated with centrosomes. J Biol Chem. 1999 Jan 29;274(5):3055-66. [PubMed:9915845 ] Shanks RA, Larocca MC, Berryman M, Edwards JC, Urushidani T, Navarre J, Goldenring JR: AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member. J Biol Chem. 2002 Oct 25;277(43):40973-80. Epub 2002 Aug 5. [PubMed:12163479 ] Larocca MC, Shanks RA, Tian L, Nelson DL, Stewart DM, Goldenring JR: AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus. Mol Biol Cell. 2004 Jun;15(6):2771-81. Epub 2004 Mar 26. [PubMed:15047863 ] Chen L, Marquardt ML, Tester DJ, Sampson KJ, Ackerman MJ, Kass RS: Mutation of an A-kinase-anchoring protein causes long-QT syndrome. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20990-5. Epub 2007 Dec 19. [PubMed:18093912 ]