Showing Protein Glycodelin (HMDBP02836)

• 8343

1. GD
2. PAEG
3. PEG
4. PP14
5. Placental protein 14
6. Pregnancy-associated endometrial alpha-2 globulin
7. Progestagen-associated endometrial protein
8. Progesterone-associated endometrial protein

1. Secreted

>568 bp
CTCAGAGCCACCCACAGCCGCAGCCATGCTGTGCCTCCTGCTCACCCTGGGCGTGGCCCT
GGTCTGTGGTGTCCCGGCCATGGACATCCCCCAGACCAAGCAGGACCTGGAGCTCCCAAA
GTTGGCAGGGACCTGGCACTCCATGGCCATGGCGACCAACAACATCTCCCTCATGGCGAC
ACTGAAGGCCCCTCTGAGGGTCCACATCACCTCACTGTTGCCCACCCCCGAGGACAACCT
GGAGATCGTTCTGCACAGATGGGAGAACAACAGCTGTGTTGAGAAGAAGGTCCTTGGAGA
GAAGACTGAGAATCCAAAGAAGTTCAAGATCAACTATACGGTGGCGAACGAGGCCACGCT
GCTCGATACTGACTACGACAATTTCCTGTTTCTCTGCCTACAGGACACCACCACCCCCAT
CCAGAGCATGATGTGCCAGTACCTGGCCAGAGTCCTGGTGGAGGACGATGAGATCATGCA
GGGATTCATCAGGGCTTTCAGGCCCCTGCCCAGGCACCTATGGTACTTGCTGGACTTGAA
ACAGATGGAAGAGCCGTGCCGTTTCTAG

• Lipocalin (PF00061 )

• 1-18

• None

>Glycodelin
MLCLLLTLGVALVCGVPAMDIPQTKQDLELPKLAGTWHSMAMATNNISLMATLKAPLRVH
ITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNF
LFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF

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3. Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Blocker H, Heubner D, Hoerlein A, Michel G, Wedler H, Kohrer K, Ottenwalder B, Poustka A, Wiemann S, Schupp I: The full-ORF clone resource of the German cDNA Consortium. BMC Genomics. 2007 Oct 31;8:399. [PubMed:17974005 ]
4. Julkunen M, Seppala M, Janne OA: Complete amino acid sequence of human placental protein 14: a progesterone-regulated uterine protein homologous to beta-lactoglobulins. Proc Natl Acad Sci U S A. 1988 Dec;85(23):8845-9. [PubMed:3194393 ]
5. Vaisse C, Atger M, Potier B, Milgrom E: Human placental protein 14 gene: sequence and characterization of a short duplication. DNA Cell Biol. 1990 Jul-Aug;9(6):401-13. [PubMed:2206398 ]
6. Garde J, Bell SC, Eperon IC: Multiple forms of mRNA encoding human pregnancy-associated endometrial alpha 2-globulin, a beta-lactoglobulin homologue. Proc Natl Acad Sci U S A. 1991 Mar 15;88(6):2456-60. [PubMed:2006183 ]
7. Bell SC, Keyte JW, Waites GT: Pregnancy-associated endometrial alpha 2-globulin, the major secretory protein of the luteal phase and first trimester pregnancy endometrium, is not glycosylated prolactin but related to beta-lactoglobulins. J Clin Endocrinol Metab. 1987 Nov;65(5):1067-71. [PubMed:3667877 ]
8. Huhtala ML, Seppala M, Narvanen A, Palomaki P, Julkunen M, Bohn H: Amino acid sequence homology between human placental protein 14 and beta-lactoglobulins from various species. Endocrinology. 1987 Jun;120(6):2620-2. [PubMed:3569148 ]
9. Vigne JL, Hornung D, Mueller MD, Taylor RN: Purification and characterization of an immunomodulatory endometrial protein, glycodelin. J Biol Chem. 2001 May 18;276(20):17101-5. Epub 2001 Mar 5. [PubMed:11278680 ]
10. Dell A, Morris HR, Easton RL, Panico M, Patankar M, Oehniger S, Koistinen R, Koistinen H, Seppala M, Clark GF: Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities. J Biol Chem. 1995 Oct 13;270(41):24116-26. [PubMed:7592613 ]
11. Morris HR, Dell A, Easton RL, Panico M, Koistinen H, Koistinen R, Oehninger S, Patankar MS, Seppala M, Clark GF: Gender-specific glycosylation of human glycodelin affects its contraceptive activity. J Biol Chem. 1996 Dec 13;271(50):32159-67. [PubMed:8943270 ]
12. Koistinen H, Koistinen R, Dell A, Morris HR, Easton RL, Patankar MS, Oehninger S, Clark GF, Seppala M: Glycodelin from seminal plasma is a differentially glycosylated form of contraceptive glycodelin-A. Mol Hum Reprod. 1996 Oct;2(10):759-65. [PubMed:9239694 ]