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Identification
HMDB Protein ID HMDBP07412
Secondary Accession Numbers
  • 13102
Name FAD synthase
Synonyms
  1. FAD pyrophosphorylase
  2. FAD synthase region
  3. FMN adenylyltransferase
  4. Flavin adenine dinucleotide synthase
  5. Molybdenum cofactor biosynthesis protein-like region
Gene Name FLAD1
Protein Type Unknown
Biological Properties
General Function Involved in FMN adenylyltransferase activity
Specific Function Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
Pathways
  • FAD biosynthesis
  • Riboflavin metabolism
  • Riboflavin Metabolism
Reactions
Adenosine triphosphate + Flavin mononucleotide → Pyrophosphate + FAD details
GO Classification
Biological Process
riboflavin metabolic process
FAD biosynthetic process
Mo-molybdopterin cofactor biosynthetic process
Cellular Component
cytosol
Function
fmn adenylyltransferase activity
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
nucleotidyltransferase activity
adenylyltransferase activity
Molecular Function
ATP binding
FMN adenylyltransferase activity
Process
fadh2 metabolic process
fad biosynthetic process
metabolic process
coenzyme biosynthetic process
cellular metabolic process
oxidoreduction coenzyme metabolic process
cofactor metabolic process
coenzyme metabolic process
mo-molybdopterin cofactor biosynthetic process
Cellular Location Not Available
Gene Properties
Chromosome Location 1
Locus 1q21.3
SNPs FLAD1
Gene Sequence
>1764 bp
ATGGGTTGGGATTTGGGAACACGTTTATTCCAGAGGCAGGAACAAAGGAGTCGCTTGTCA
AGGATCTGGTTAGAGAAGACTAGGGTCTTCCTCGAAGGAAGCACGCGCACGCCTGCTCTC
CCCCATTGTCTTTTCTGGCTTCTCCAGGTTCCCTCGACCCAGGACCCCCTGTTCCCAGGC
TATGGCCCCCAGTGCCCTGTAGACCTGGCAGGCCCCCCGTGCTTGCGACCCCTATTTGGG
GGTCTGGGTGGCTACTGGAGGGCCTTGCAGAGGGGCAGAGAAGGCAGGACCATGACATCT
AGGGCCTCTGAACTTTCTCCGGGGCGCAGCGTGACGGCTGGCATCATCATTGTTGGAGAT
GAGATCCTTAAGGGACACACTCAGGACACCAACACCTTCTTTCTGTGCCGGACACTGCGC
TCCCTAGGGGTCCAGGTTTGCCGAGTCTCAGTTGTACCTGATGAGGTAGCCACCATTGCA
GCTGAGGTCACTTCTTTCTCCAACCGCTTCACCCATGTCCTCACAGCAGGGGGCATCGGC
CCCACTCATGATGATGTGACCTTTGAGGCAGTGGCACAGGCCTTTGGAGATGAGCTGAAG
CCACACCCCAAGTTGGAAGCAGCCACCAAAGCCCTAGGAGGGGAAGGCTGGGAGAAGCTA
TCATTGGTGCCCTCCTCTGCCCGCCTGCATTATGGCACAGATCCTTGCACTGGTCAACCT
TTCAGATTCCCTCTGGTCTCCGTCCGAAACGTCTACCTCTTCCCAGGCATTCCAGAGCTG
CTGCGGCGGGTGCTGGAGGGGATGAAGGGACTATTCCAAAACCCAGCTGTTCAGTTCCAC
TCAAAGGAGCTATATGTGGCTGCTGATGAAGCCTCCATCGCCCCCATTCTGGCTGAGGCC
CAGGCCCACTTTGGACGTAGGCTTGGCCTGGGTTCCTACCCTGACTGGGGCAGCAACTAC
TATCAGGTGAAGCTGACTCTAGACTCAGAGGAAGAAGGACCCCTGGAGGAATGCTTGGCC
TACCTGACTGCCCGTTTGCCCCAGGGATCGCTGGTCCCCTACATGCCCAACGCTGTGGAG
CAGGCCAGTGAGGCTGTATACAAACTCGCTGAATCAGGGTCTTCTTTGGGGAAAAAGGTG
GCAGGTGCCCTACAGACCATTGAGACCTCCCTGGCTCAGTACAGCCTCACCCAGCTCTGT
GTGGGCTTCAACGGGGGCAAAGACTGCACTGCCCTCCTGCACCTCTTCCATGCAGCTGTG
CAGAGGAAATTACCTGATGTTCCAAACCCCCTCCAGATCCTGTATATCCGCAGCATCTCC
CCTTTCCCTGAGCTGGAACAGTTTCTACAGGACACTATCAAGAGGTATAATCTGCAGATG
TTGGAAGCTGAGGGCAGCATGAAGCAGGCCCTGGGTGAACTGCAGGCACGGCACCCCCAG
CTGGAGGCTGTCCTTATGGGCACCCGCCGGACTGACCCCTACTCCTGTAGCCTCTGCCCT
TTCAGCCCCACTGACCCAGGCTGGCCCGCATTCATGCGCATCAACCCACTGCTGGACTGG
ACCTACAGAGACATCTGGGATTTTCTGCGTCAGCTGTTTGTCCCATACTGTATCCTGTAT
GACCGAGGATACACATCACTGGGGAGTCGGGAGAATACCGTGCGGAACCCGGCCCTGAAG
TGCCTGAGCCCAGGAGGACACCCCACATACCGTCCAGCCTATCTACTGGAGAACGAAGAA
GAGGAGCGGAACTCCCGCACATGA
Protein Properties
Number of Residues 587
Molecular Weight 49197.795
Theoretical pI 5.962
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>FAD synthase
MGWDLGTRLFQRQEQRSRLSRIWLEKTRVFLEGSTRTPALPHCLFWLLQVPSTQDPLFPG
YGPQCPVDLAGPPCLRPLFGGLGGYWRALQRGREGRTMTSRASELSPGRSVTAGIIIVGD
EILKGHTQDTNTFFLCRTLRSLGVQVCRVSVVPDEVATIAAEVTSFSNRFTHVLTAGGIG
PTHDDVTFEAVAQAFGDELKPHPKLEAATKALGGEGWEKLSLVPSSARLHYGTDPCTGQP
FRFPLVSVRNVYLFPGIPELLRRVLEGMKGLFQNPAVQFHSKELYVAADEASIAPILAEA
QAHFGRRLGLGSYPDWGSNYYQVKLTLDSEEEGPLEECLAYLTARLPQGSLVPYMPNAVE
QASEAVYKLAESGSSLGKKVAGALQTIETSLAQYSLTQLCVGFNGGKDCTALLHLFHAAV
QRKLPDVPNPLQILYIRSISPFPELEQFLQDTIKRYNLQMLEAEGSMKQALGELQARHPQ
LEAVLMGTRRTDPYSCSLCPFSPTDPGWPAFMRINPLLDWTYRDIWDFLRQLFVPYCILY
DRGYTSLGSRENTVRNPALKCLSPGGHPTYRPAYLLENEEEERNSRT
GenBank ID Protein 41872389
UniProtKB/Swiss-Prot ID Q8NFF5
UniProtKB/Swiss-Prot Entry Name FAD1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_025207.4
GeneCard ID FLAD1
GenAtlas ID FLAD1
HGNC ID HGNC:24671
References
General References
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