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Showing Protein Tuberoinfundibular peptide of 39 residues (HMDBP08054)
Identification | |
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HMDB Protein ID | HMDBP08054 |
Secondary Accession Numbers |
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Name | Tuberoinfundibular peptide of 39 residues |
Synonyms |
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Gene Name | PTH2 |
Protein Type | Unknown |
Biological Properties | |
General Function | Involved in neuropeptide signaling pathway |
Specific Function | Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action on PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits |
Pathways | Not Available |
Reactions | Not Available |
GO Classification | Not Available |
Cellular Location |
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Gene Properties | |
Chromosome Location | Chromosome:1 |
Locus | 19q13.33 |
SNPs | PTH2 |
Gene Sequence |
>303 bp ATGGAGACCCGCCAGGTGTCCAGGAGCCCTCGGGTTCGGCTGCTGCTGCTGCTGCTGCTG CTGCTGGTGGTGCCCTGGGGCGTCCGCACTGCCTCGGGAGTCGCCCTGCCCCCGGTCGGG GTCCTCAGCCTCCGCCCCCCAGGACGGGCCTGGGCGGATCCCGCCACCCCCAGGCCGCGG AGGAGCCTGGCGCTGGCGGACGACGCGGCCTTCCGGGAACGCGCGCGGTTGCTGGCCGCC CTCGAGCGCCGCCACTGGCTGAACTCGTACATGCACAAGCTGCTGGTGTTGGATGCGCCC TGA |
Protein Properties | |
Number of Residues | 100 |
Molecular Weight | 11202.1 |
Theoretical pI | 12.33 |
Pfam Domain Function | Not Available |
Signals |
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Transmembrane Regions |
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Protein Sequence |
>Tuberoinfundibular peptide of 39 residues METRQVSRSPRVRLLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPRPR RSLALADDAAFRERARLLAALERRHWLNSYMHKLLVLDAP |
External Links | |
GenBank ID Protein | Not Available |
UniProtKB/Swiss-Prot ID | Q96A98 |
UniProtKB/Swiss-Prot Entry Name | TIP39_HUMAN |
PDB IDs | Not Available |
GenBank Gene ID | AY037555 |
GeneCard ID | PTH2 |
GenAtlas ID | PTH2 |
HGNC ID | HGNC:30828 |
References | |
General References |
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