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Identification
HMDB Protein ID HMDBP08762
Secondary Accession Numbers
  • 14485
Name Magnesium transporter MRS2 homolog, mitochondrial
Synonyms
  1. MRS2-like protein
Gene Name MRS2
Protein Type Unknown
Biological Properties
General Function Involved in ion transport
Specific Function Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix.
Pathways Not Available
Reactions Not Available
GO Classification
Cellular Component
integral to membrane
mitochondrial inner membrane
Molecular Function
magnesium ion transmembrane transporter activity
Cellular Location
  1. Mitochondrion inner membrane
  2. Multi-pass membrane protein
Gene Properties
Chromosome Location 6
Locus 6p22.3-p22.1
SNPs MRS2
Gene Sequence
>1332 bp
ATGGAATGCCTGCGCAGTTTACCCTGCCTCCTGCCCCGCGCGATGAGACTTCCCCGGCGG
ACGCTGTGTGCCCTGGCCTTGGACGTGACCTCTGTGGGTCCTCCCGTTGCTGCCTGCGGC
CGCCGAGCCAACCTGATTGGAAGGAGCCGAGCGGCGCAGCTTTGCGGGCCCGACCGGCTC
CGCGTGGCAGGTGAAGTGCACCGGTTTAGAACCTCTGACGTCTCTCAAGCCACTTTAGCC
AGTGTAGCCCCAGTATTTACTGTGACAAAATTTGACAAACAGGGAAACGTTACTTCTTTT
GAAAGGAAGAAAACTGAATTATACCAAGAGTTAGGTCTTCAAGCCAGAGATTTGAGATTT
CAGCATGTAATGAGTATCACAGTCAGAAACAATAGGATTATCATGAGAATGGAGTATTTG
AAAGCTGTGATAACTCCAGAGTGTCTTCTGATATTAGATTATCGTAATTTAAACTTAGAG
CAATGGCTGTTCCGGGAACTCCCTTCACAGTTGTCTGGAGAGGGTCAACTCGTTACATAC
CCTTTACCTTTTGAGTTTAGAGCTATAGAAGCACTCCTGCAATATTGGATCAACACCCTT
CAGGGGAAACTTAGCATTTTGCAGCCACTGATCCTTGAGACCTTGGATGCTTTGGTGGAC
CCCAAACATTCTTCTGTAGACAGAAGCAAACTGCACATTTTACTACAGAATGGCAAAAGT
CTATCAGAGTTAGAAACAGATATTAAAATTTTCAAAGAGTCAATTTTGGAGATCTTGGAT
GAGGAAGAGTTGCTAGAAGAGCTCTGTGTATCAAAATGGAGTGACCCACAAGTCTTTGAA
AAGAGCAGTGCTGGGATTGACCATGCAGAAGAAATGGAGTTGCTGTTGGAAAACTACTAC
CGATTGGCTGACGATCTCTCCAATGCAGCTCGTGAGCTTAGGGTGCTGATTGATGATTCA
CAAAGTATTATTTTCATTAATCTGGACAGCCACCGAAACGTGATGATGAGGTTGAATCTA
CAGCTGACCATGGGAACCTTCTCTCTTTCGCTCTTTGGACTAATGGGAGTTGCTTTTGGA
ATGAATTTGGAATCTTCCCTTGAAGAGGACCATAGAATTTTTTGGCTGATTACAGGAATT
ATGTTCATGGGAAGTGGCCTCATCTGGAGGCGCCTGCTTTCATTCCTTGGACGACAGCTA
GAAGCTCCATTGCCTCCTATGATGGCTTCTTTACCTAAAAAGACTCTTCTGGCAGATAGA
AGCATGGAATTGAAAAATAGCCTCAGACTGGATGGACTTGGATCAGGAAGGAGCATCCTA
ACAAACCGTTAG
Protein Properties
Number of Residues 443
Molecular Weight 50317.01
Theoretical pI 6.877
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Magnesium transporter MRS2 homolog, mitochondrial
MECLRSLPCLLPRAMRLPRRTLCALALDVTSVGPPVAACGRRANLIGRSRAAQLCGPDRL
RVAGEVHRFRTSDVSQATLASVAPVFTVTKFDKQGNVTSFERKKTELYQELGLQARDLRF
QHVMSITVRNNRIIMRMEYLKAVITPECLLILDYRNLNLEQWLFRELPSQLSGEGQLVTY
PLPFEFRAIEALLQYWINTLQGKLSILQPLILETLDALVDPKHSSVDRSKLHILLQNGKS
LSELETDIKIFKESILEILDEEELLEELCVSKWSDPQVFEKSSAGIDHAEEMELLLENYY
RLADDLSNAARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFG
MNLESSLEEDHRIFWLITGIMFMGSGLIWRRLLSFLGRQLEAPLPPMMASLPKKTLLADR
SMELKNSLRLDGLGSGRSILTNR
GenBank ID Protein 9858855
UniProtKB/Swiss-Prot ID Q9HD23
UniProtKB/Swiss-Prot Entry Name MRS2_HUMAN
PDB IDs Not Available
GenBank Gene ID AF288288
GeneCard ID MRS2
GenAtlas ID MRS2
HGNC ID HGNC:13785
References
General References
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