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Showing Protein Transcription initiation factor TFIID subunit 1 (HMDBP08821)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP08821
Secondary Accession Numbers
  • 14546
Name Transcription initiation factor TFIID subunit 1
Synonyms
  1. Cell cycle gene 1 protein
  2. TAF(II)250
  3. TAFII-250
  4. TAFII250
  5. TBP-associated factor 250 kDa
  6. Transcription initiation factor TFIID 250 kDa subunit
  7. p250
Gene Name TAF1
Protein Type Unknown
Biological Properties
General Function Involved in DNA binding
Specific Function Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA- binding activity. Essential for progression of the G1 phase of the cell cycle
Pathways Not Available
Reactions Not Available
GO Classification
Component
transcription factor complex
macromolecular complex
protein complex
transcription factor tfiid complex
Function
binding
nucleic acid binding
dna binding
Process
cellular component organization or biogenesis
biological regulation
cellular component organization
regulation of biological process
cellular component assembly
regulation of metabolic process
macromolecular complex assembly
regulation of macromolecule metabolic process
regulation of gene expression
regulation of transcription
regulation of transcription, dna-dependent
protein complex assembly
transcription initiation
Cellular Location
  1. Nucleus
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs TAF1
Gene Sequence 
>5619 bp
ATGGGACCCGGCTGCGATTTGCTGCTGCGGACAGCAGCTACCATCACTGCTGCCGCCATC
ATGTCAGACACGGACAGCGACGAAGATTCCGCTGGAGGCGGCCCATTTTCTTTAGCGGGT
TTCCTTTTCGGCAACATCAATGGAGCCGGGCAGCTGGAGGGGGAAAGCGTCTTGGATGAT
GAATGTAAGAAGCACTTGGCAGGCTTGGGGGCTTTGGGGCTGGGCAGCCTGATCACTGAA
CTCACGGCAAATGAAGAATTGACCGGGACTGACGGTGCCTTGGTAAATGATGAAGGGTGG
GTTAGGAGTACAGAAGATGCTGTGGACTATTCAGACATCAATGAGGTGGCAGAAGATGAA
AGCCGAAGATACCAGCAGACGATGGGGAGCTTGCAGCCCCTTTGCCACTCAGATTATGAT
GAAGATGACTATGATGCTGATTGTGAAGACATTGATTGCAAGTTGATGCCTCCTCCACCT
CCACCCCCGGGACCAATGAAGAAGGATAAGGACCAGGATTCTATTACTGGTGAGAAAGTG
GACTTCAGTAGTTCCTCTGACTCAGAATCTGAGATGGGACCTCAGGAAGCAACACAGGCA
GAATCTGAAGATGGAAAGCTGACCCTTCCATTGGCTGGGATTATGCAGCATGATGCCACC
AAGCTGTTGCCAAGTGTCACAGAACTTTTTCCAGAATTTCGACCTGGAAAGGTGTTACGT
TTTCTACGTCTTTTTGGACCAGGGAAGAATGTCCCATCTGTTTGGCGGAGTGCTCGGAGA
AAGAGGAAGAAGAAGCACCGTGAGCTGATACAGGAAGAGCAGATCCAGGAGGTGGAGTGC
TCAGTAGAATCAGAAGTCAGCCAGAAGTCTTTGTGGAACTACGACTACGCTCCACCACCA
CCTCCAGAGCAGTGTCTCTCTGATGATGAAATCACGATGATGGCTCCTGTGGAGTCCAAA
TTTTCCCAATCAACTGGAGATATAGATAAAGTGACAGATACCAAACCAAGAGTGGCTGAG
TGGCGTTATGGGCCTGCCCGACTGTGGTATGATATGCTGGGTGTCCCTGAAGATGGCAGT
GGGTTTGACTATGGCTTCAAACTGAGAAAGACAGAACATGAACCTGTGATAAAATCTAGA
ATGATAGAGGAATTTAGGAAACTTGAGGAAAACAATGGCACTGATCTTCTGGCTGATGAA
AACTTCCTGATGGTGACACAGCTGCATTGGGAGGATGATATCATCTGGGATGGGGAGGAT
GTCAAACACAAAGGGACAAAACCTCAGCGTGCAAGCCTGGCAGGCTGGCTTCCTTCTAGC
ATGACTAGGAATGCGATGGCTTACAATGTTCAGCAAGGTTTTGCAGCCACTCTTGATGAT
GACAAACCTTGGTACTCCATTTTTCCCATTGACAATGAGGATCTGGTATATGGACGCTGG
GAGGACAATATCATTTGGGATGCTCAGGCCATGCCCCGGCTGTTGGAACCTCCTGTTTTG
ACACTTGATCCCAATGATGAGAACCTCATTTTGGAAATTCCTGATGAGAAGGAAGAGGCC
ACCTCTAACTCCCCCTCCAAGGAGAGTAAGAAGGAATCATCTCTGAAGAAGAGTCGAATT
CTCTTAGGGAAAACAGGAGTCATCAAGGAGGAACCACAGCAGAACATGTCTCAGCCAGAA
GTGAAAGATCCATGGAATCTCTCCAATGATGAGTATTATTATCCCAAGCAACAGGGTCTT
CGAGGCACCTTTGGAGGGAATATTATCCAGCATTCAATTCCTGCTGTGGAATTACGGCAG
CCCTTCTTTCCCACCCACATGGGGCCCATCAAACTCCGGCAGTTCCATCGCCCACCTCTG
AAAAAGTACTCATTTGGTGCACTTTCTCAGCCAGGTCCCCACTCAGTCCAACCTTTGCTA
AAGCACATCAAAAAAAAGGCCAAGATGAGAGAACAAGAGAGGCAAGCTTCAGGTGGTGGA
GAGATGTTTTTTATGCGCACACCTCAGGACCTCACAGGCAAAGATGGTGATCTTATTCTT
GCAGAATATAGTGAGGAAAATGGACCCTTAATGATGCAGGTTGGCATGGCAACCAAGATA
AAGAACTATTATAAACGGAAACCTGGAAAAGATCCTGGAGCACCAGATTGTAAATATGGG
GAAACTGTTTACTGCCATACATCTCCTTTCCTGGGTTCTCTCCATCCTGGCCAATTGCTG
CAAGCATTTGAGAACAACCTTTTTCGTGCTCCAATTTATCTTCATAAGATGCCAGAAACT
GATTTCTTGATCATTCGGACAAGACAGGGTTACTATATTCGGGAATTAGTGGATATTTTT
GTGGTTGGCCAGCAGTGTCCCTTGTTTGAAGTTCCTGGGCCTAACTCCAAAAGGGCCAAT
ACGCATATTCGAGACTTTCTACAGGTTTTTATTTACCGCCTTTTCTGGAAAAGTAAAGAT
CGGCCACGGAGGATACGAATGGAAGATATAAAAAAAGCCTTTCCTTCCCATTCAGAAAGC
AGCATCCGGAAGAGGCTAAAGCTCTGCGCTGACTTCAAACGCACAGGGATGGACTCAAAC
TGGTGGGTGCTTAAGTCTGATTTTCGTTTACCAACGGAAGAAGAGATCAGAGCTATGGTG
TCACCAGAGCAGTGCTGTGCTTATTATAGCATGATAGCTGCAGAGCAACGACTGAAGGAT
GCTGGCTATGGTGAGAAATCCTTTTTTGCTCCAGAAGAAGAAAATGAGGAAGATTTCCAG
ATGAAGATTGATGATGAAGTTCGCACTGCCCCTTGGAACACCACAAGGGCCTTCATTGCT
GCCATGAAGGGCAAGTGTCTGCTAGAGGTGACTGGGGTGGCAGATCCCACGGGGTGTGGT
GAAGGATTCTCCTATGTGAAGATTCCAAACAAACCAACACAGCAGAAGGATGATAAAGAA
CCGCAGCCAGTGAAGAAGACAGTGACAGGAACAGATGCAGACCTTCGTCGCCTTTCCCTG
AAAAATGCCAAGCAACTTCTACGTAAATTTGGTGTGCCTGAGGAAGAGATTAAAAAGTTG
TCCCGCTGGGAAGTGATTGATGTGGTGCGCACAATGTCAACAGAACAGGCTCGTTCTGGA
GAGGGGCCCATGAGTAAATTTGCCCGTGGATCAAGGTTTTCTGTGGCTGAGCATCAAGAG
CGTTACAAAGAGGAATGTCAGCGCATCTTTGACCTACAGAACAAGGTTCTGTCATCAACT
GAAGTCTTATCAACTGACACAGACAGCAGCTCAGCTGAAGATAGTGACTTTGAAGAAATG
GGAAAGAACATTGAGAACATGTTGCAGAACAAGAAAACCAGCTCTCAGCTTTCACGTGAA
CGGGAGGAACAGGAGCGGAAGGAACTACAGCGAATGCTACTGGCAGCAGGCTCAGCAGCA
TCCGGAAACAATCACAGAGATGATGACACAGCTTCCGTGACTAGCCTTAACTCTTCTGCC
ACTGGACGCTGTCTCAAGATTTATCGCACGTTTCGAGATGAAGAGGGGAAAGAGTATGTT
CGCTGTGAGACAGTCCGAAAACCAGCTGTCATTGATGCCTATGTGCGCATACGGACTACA
AAAGATGAGGAATTCATTCGAAAATTTGCCCTTTTTGATGAACAACATCGGGAAGAGATG
CGAAAAGAACGGCGGAGGATTCAAGAGCAACTGAGGCGGCTTAAGAGGAACCAGGAAAAG
GAGAAGCTTAAGGGTCCTCCTGAGAAGAAGCCCAAGAAAATGAAGGAGCGTCCTGACCTA
AAACTGAAATGTGGGGCATGTGGTGCCATTGGACACATGAGGACTAACAAATTCTGCCCC
CTCTATTATCAAACAAATGCGCCACCTTCCAACCCTGTTGCCATGACAGAAGAACAGGAG
GAGGAGTTGGAAAAGACAGTCATTCATAATGATAATGAAGAACTTATCAAGGTTGAAGGG
ACCAAAATTGTCTTGGGGAAACAGCTAATTGAGAGTGCGGATGAGGTTCGCAGAAAATCT
CTGGTTCTCAAGTTTCCTAAACAGCAGCTTCCTCCAAAGAAGAAACGGCGAGTTGGAACC
ACTGTTCACTGTGACTATTTGAATAGACCTCATAAGTCCATCCACCGGCGCCGCACAGAC
CCTATGGTGACGCTGTCGTCCATCTTGGAGTCTATCATCAATGACATGAGAGATCTTCCA
AATACATACCCTTTCCACACTCCAGTCAATGCAAAGGTTGTAAAGGACTACTACAAAATC
ATCACTCGGCCAATGGACCTACAAACACTCCGCGAAAACGTGCGTAAACGCCTCTACCCA
TCTCGGGAAGAGTTCAGAGAGCATCTGGAGCTAATTGTGAAAAATAGTGCAACCTACAAT
GGGCCAAAACACTCATTGACTCAGATCTCTCAATCCATGCTGGATCTCTGTGATGAAAAA
CTCAAAGAGAAAGAAGACAAATTAGCTCGCTTAGAGAAAGCTATCAACCCCTTGCTGGAT
GATGATGACCAAGTGGCGTTTTCTTTCATTCTGGACAACATTGTCACCCAGAAAATGATG
GCAGTTCCAGATTCTTGGCCATTTCATCACCCAGTTAATAAGAAATTTGTTCCAGATTAT
TACAAAGTGATTGTCAATCCAATGGATTTAGAGACCATACGTAAGAACATCTCCAAGCAC
AAGTATCAGAGTCGGGAGAGCTTTCTGGATGATGTAAACCTTATTCTGGCCAACAGTGTT
AAGTATAATGGACCTGAGAGTCAGTATACTAAGACTGCCCAGGAGATTGTGAACGTCTGT
TACCAGACATTGACTGAGTATGATGAACATTTGACTCAACTTGAGAAGGATATTTGTACT
GCTAAAGAAGCAGCTTTGGAGGAAGCAGAATTAGAAAGCCTGGACCCAATGACCCCAGGG
CCCTACACGCCTCAGCCTCCTGATTTGTATGATACCAACACATCCCTCAGTATGTCTCGA
GATGCCTCTGTATTTCAAGATGAGAGCAATATGTCTGTCTTGGATATTCCCAGTGCCACT
CCAGAAAAGCAGGTAACACAGGAAGGTGAAGATGGAGATGGTGATCTTGCAGATGAAGAG
GAAGGAACTGTACAACAGCCTCAAGCCAGTGTCCTGTATGAGGATTTGCTTATGTCTGAA
GGAGAAGATGATGAGGAAGATGCTGGGAGTGATGAAGAAGGAGACAATCCTTTCTCTGCT
ATCCAGCTGAGTGAAAGTGGAAGTGACTCTGATGTGGGATCTGGTGGAATAAGACCCAAA
CAACCCCGCATGCTTCAGGAGAACACAAGGATGGACATGGAAAATGAAGAAAGCATGATG
TCCTATGAGGGAGACGGTGGGGAGGCTTCCCATGGTTTGGAGGATAGCAACATCAGTTAT
GGGAGCTATGAGGAGCCTGATCCCAAGTCGAACACCCAAGACACAAGCTTCAGCAGCATC
GGTGGGTATGAGGTATCAGAGGAGGAAGAAGATGAGGAGGAGGAAGAGCAGCGCTCTGGG
CCGAGCGTACTAAGCCAGGTCCACCTGTCAGAGGACGAGGAGGACAGTGAGGATTTCCAC
TCCATTGCTGGGGACAGTGACTTGGACTCTGATGAATGA
Protein Properties
Number of Residues 1872
Molecular Weight 212675.5
Theoretical pI 4.7
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence 
>Transcription initiation factor TFIID subunit 1
MGPGCDLLLRTAATITAAAIMSDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESVLDD
ECKKHLAGLGALGLGSLITELTANEELTGTDGALVNDEGWVRSTEDAVDYSDINEVAEDE
SRRYQQTMGSLQPLCHSDYDEDDYDADCEDIDCKLMPPPPPPPGPMKKDKDQDSITGEKV
DFSSSSDSESEMGPQEATQAESEDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLR
FLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEVECSVESEVSQKSLWNYDYAPPP
PPEQCLSDDEITMMAPVESKFSQSTGDIDKVTDTKPRVAEWRYGPARLWYDMLGVPEDGS
GFDYGFKLRKTEHEPVIKSRMIEEFRKLEENNGTDLLADENFLMVTQLHWEDDIIWDGED
VKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFAATLDDDKPWYSIFPIDNEDLVYGRW
EDNIIWDAQAMPRLLEPPVLTLDPNDENLILEIPDEKEEATSNSPSKESKKESSLKKSRI
LLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQGLRGTFGGNIIQHSIPAVELRQ
PFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGG
EMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYG
ETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPETDFLIIRTRQGYYIRELVDIF
VVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSES
SIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKD
AGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCG
EGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKL
SRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSST
EVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGSAA
SGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKPAVIDAYVRIRTT
KDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDL
KLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEG
TKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTD
PMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYP
SREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLD
DDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKH
KYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTEYDEHLTQLEKDICT
AKEAALEEAELESLDPMTPGPYTPQPPDLYDTNTSLSMSRDASVFQDESNMSVLDIPSAT
PEKQVTQEGEDGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSA
IQLSESGSDSDVGSGGIRPKQPRMLQENTRMDMENEESMMSYEGDGGEASHGLEDSNISY
GSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEEEQRSGPSVLSQVHLSEDEEDSEDFH
SIAGDSDLDSDE
GenBank ID Protein 20357588
UniProtKB/Swiss-Prot ID P21675
UniProtKB/Swiss-Prot Entry Name TAF1_HUMAN
PDB IDs
GenBank Gene ID NM_138923.2
GeneCard ID TAF1
GenAtlas ID TAF1
HGNC ID HGNC:11535
References
General References
  1. Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. Sci Signal. 2009 Aug 18;2(84):ra46. doi: 10.1126/scisignal.2000007. [PubMed:19690332 ]
  2. Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR: Patterns of somatic mutation in human cancer genomes. Nature. 2007 Mar 8;446(7132):153-8. [PubMed:17344846 ]
  3. Dou Y, Milne TA, Tackett AJ, Smith ER, Fukuda A, Wysocka J, Allis CD, Chait BT, Hess JL, Roeder RG: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell. 2005 Jun 17;121(6):873-85. [PubMed:15960975 ]
  4. Li HH, Li AG, Sheppard HM, Liu X: Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression. Mol Cell. 2004 Mar 26;13(6):867-78. [PubMed:15053879 ]
  5. Sekiguchi T, Nohiro Y, Nakamura Y, Hisamoto N, Nishimoto T: The human CCG1 gene, essential for progression of the G1 phase, encodes a 210-kilodalton nuclear DNA-binding protein. Mol Cell Biol. 1991 Jun;11(6):3317-25. [PubMed:2038334 ]
  6. Sekiguchi T, Miyata T, Nishimoto T: Molecular cloning of the cDNA of human X chromosomal gene (CCG1) which complements the temperature-sensitive G1 mutants, tsBN462 and ts13, of the BHK cell line. EMBO J. 1988 Jun;7(6):1683-7. [PubMed:3169001 ]
  7. Ruppert S, Wang EH, Tjian R: Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation. Nature. 1993 Mar 11;362(6416):175-9. [PubMed:7680771 ]
  8. Nolte D, Niemann S, Muller U: Specific sequence changes in multiple transcript system DYT3 are associated with X-linked dystonia parkinsonism. Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10347-52. Epub 2003 Aug 19. [PubMed:12928496 ]
  9. Hisatake K, Hasegawa S, Takada R, Nakatani Y, Horikoshi M, Roeder RG: The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1. Nature. 1993 Mar 11;362(6416):179-81. [PubMed:8450888 ]
  10. Dikstein R, Ruppert S, Tjian R: TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74. Cell. 1996 Mar 8;84(5):781-90. [PubMed:8625415 ]
  11. Damania B, Alwine JC: TAF-like function of SV40 large T antigen. Genes Dev. 1996 Jun 1;10(11):1369-81. [PubMed:8647434 ]
  12. O'Brien T, Tjian R: Functional analysis of the human TAFII250 N-terminal kinase domain. Mol Cell. 1998 May;1(6):905-11. [PubMed:9660973 ]
  13. Siegert JL, Robbins PD: Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250. Mol Cell Biol. 1999 Jan;19(1):846-54. [PubMed:9858607 ]
  14. Munakata T, Adachi N, Yokoyama N, Kuzuhara T, Horikoshi M: A human homologue of yeast anti-silencing factor has histone chaperone activity. Genes Cells. 2000 Mar;5(3):221-33. [PubMed:10759893 ]
  15. Solow S, Salunek M, Ryan R, Lieberman PM: Taf(II) 250 phosphorylates human transcription factor IIA on serine residues important for TBP binding and transcription activity. J Biol Chem. 2001 May 11;276(19):15886-92. Epub 2001 Feb 20. [PubMed:11278496 ]
  16. Chimura T, Kuzuhara T, Horikoshi M: Identification and characterization of CIA/ASF1 as an interactor of bromodomains associated with TFIID. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9334-9. Epub 2002 Jul 1. [PubMed:12093919 ]
  17. Umehara T, Horikoshi M: Transcription initiation factor IID-interactive histone chaperone CIA-II implicated in mammalian spermatogenesis. J Biol Chem. 2003 Sep 12;278(37):35660-7. Epub 2003 Jul 2. [PubMed:12842904 ]
  18. Jacobson RH, Ladurner AG, King DS, Tjian R: Structure and function of a human TAFII250 double bromodomain module. Science. 2000 May 26;288(5470):1422-5. [PubMed:10827952 ]
  19. Makino S, Kaji R, Ando S, Tomizawa M, Yasuno K, Goto S, Matsumoto S, Tabuena MD, Maranon E, Dantes M, Lee LV, Ogasawara K, Tooyama I, Akatsu H, Nishimura M, Tamiya G: Reduced neuron-specific expression of the TAF1 gene is associated with X-linked dystonia-parkinsonism. Am J Hum Genet. 2007 Mar;80(3):393-406. Epub 2007 Jan 23. [PubMed:17273961 ]