Hmdb loader
Survey
Identification
HMDB Protein ID HMDBP09150
Secondary Accession Numbers
  • 14905
Name Dipeptidase 2
Synonyms Not Available
Gene Name DPEP2
Protein Type Enzyme
Biological Properties
General Function Involved in metalloexopeptidase activity
Specific Function Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4)
Pathways Not Available
Reactions Not Available
GO Classification
Function
metalloexopeptidase activity
exopeptidase activity
catalytic activity
hydrolase activity
dipeptidase activity
dipeptidyl-peptidase activity
peptidase activity
peptidase activity, acting on l-amino acid peptides
metallopeptidase activity
Process
metabolic process
macromolecule metabolic process
protein metabolic process
proteolysis
Cellular Location
  1. Lipid-anchor
  2. GPI-anchor
  3. Membrane
Gene Properties
Chromosome Location Chromosome:1
Locus 16q22.1
SNPs DPEP2
Gene Sequence
>1461 bp
ATGCAGCCCTCCGGCCTCGAGGGTCCCGGCACGTTTGGTCGGTGGCCTCTGCTGAGTCTG
CTGCTCCTGCTGCTGCTGCTCCAGCCTGTAACCTGTGCCTACACCACGCCAGGCCCCCCC
AGAGCCCTCACCACGCTGGGCGCCCCCAGAGCCCACACCATGCCGGGCACCTACGCTCCC
TCGACCACACTCAGTAGTCCCAGCACCCAGGGCCTGCAAGAGCAGGCACGGGCCCTGATG
CGGGACTTCCCGCTCGTGGACGGCCACAACGACCTGCCCCTGGTCCTAAGGCAGGTTTAC
CAGAAAGGGCTACAGGATGTTAACCTGCGCAATTTCAGCTACGGCCAGACCAGCCTGGAC
AGGCTTAGAGATGGCCTCGTGGGCGCCCAGTTCTGGTCAGCCTATGTGCCATGCCAGACC
CAGGACCGGGATGCCCTGCGCCTCACCCTGGAGCAGATTGACCTCATACGCCGCATGTGT
GCCTCCTATTCTGAGCTGGAGCTTGTGACCTCGGCTAAAGCTCTGAACGACACTCAGAAA
TTGGCCTGCCTCATCGGTGTAGAGGGTGGCCACTCGCTGGACAATAGCCTCTCCATCTTA
CGTACCTTCTACATGCTGGGAGTGCGCTACCTGACGCTCACCCACACCTGCAACACACCC
TGGGCAGAGAGCTCCGCTAAGGGCGTCCACTCCTTCTACAACAACATCAGCGGGCTGACT
GACTTTGGTGAGAAGGTGGTGGCAGAAATGAACCGCCTGGGCATGATGGTAGACTTATCC
CATGTCTCAGATGCTGTGGCACGGCGGGCCCTGGAAGTGTCACAGGCACCTGTGATCTTC
TCCCACTCGGCTGCCCGGGGTGTGTGCAACAGTGCTCGGAATGTTCCTGATGACATCCTG
CAGCTTCTGAAGAAGAACGGTGGCGTCGTGATGGTGTCTTTGTCCATGGGAGTAATACAG
TGCAACCCATCAGCCAATGTGTCCACTGTGGCAGATCACTTCGACCACATCAAGGCTGTC
ATTGGATCCAAGTTCATCGGGATTGGTGGAGATTATGATGGGGCCGGCAAATTCCCTCAG
GGGCTGGAAGACGTGTCCACATACCCGGTCCTGATAGAGGAGTTGCTGAGTCGTGGCTGG
AGTGAGGAAGAGCTTCAGGGTGTCCTTCGTGGAAACCTGCTGCGGGTCTTCAGACAAGTG
GAAAAGGTACAGGAAGAAAACAAATGGCAAAGCCCCTTGGAGGACAAGTTCCCGGATGAG
CAGCTGAGCAGTTCCTGCCACTCCGACCTCTCACGTCTGCGTCAGAGACAGAGTCTGACT
TCAGGCCAGGAACTCACTGAGATTCCCATACACTGGACAGCCAAGTTACCAGCCAAGTGG
TCAGTCTCAGAGTCCTCCCCCCACATGGCCCCAGTCCTTGCAGTTGTGGCCACCTTCCCA
GTCCTTATTCTGTGGCTCTGA
Protein Properties
Number of Residues 486
Molecular Weight 53305.5
Theoretical pI 6.37
Pfam Domain Function
Signals
  • 1-32
Transmembrane Regions
  • None
Protein Sequence
>Dipeptidase 2
MQPSGLEGPGTFGRWPLLSLLLLLLLLQPVTCAYTTPGPPRALTTLGAPRAHTMPGTYAP
STTLSSPSTQGLQEQARALMRDFPLVDGHNDLPLVLRQVYQKGLQDVNLRNFSYGQTSLD
RLRDGLVGAQFWSAYVPCQTQDRDALRLTLEQIDLIRRMCASYSELELVTSAKALNDTQK
LACLIGVEGGHSLDNSLSILPTFYMLGVRYLTLTHTCNTPWAESSAKGVHSFYNNISGLT
DFGEKVVAEMNRLGMMVDLSHVSDAVARRALEVSQAPVIFSHSAARGVCNSARNVPDDIL
QLLKKNGGVVMVSLSMGVIQCNPSANVSTVADHFDHIKAVIGSKFIGIGGDYDGAGKFPQ
GLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDE
QLSSSCHSDLSRLRQRQSLTSGQELTEIPIHWTAKLPAKWSVSESSPHMAPVLAVVATFP
VLILWL
GenBank ID Protein 11641269
UniProtKB/Swiss-Prot ID Q9H4A9
UniProtKB/Swiss-Prot Entry Name DPEP2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_022355.2
GeneCard ID DPEP2
GenAtlas ID DPEP2
HGNC ID HGNC:23028
References
General References
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