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| Identification |
|---|
| HMDB Protein ID
| HMDBP09534 |
| Secondary Accession Numbers
| |
| Name
| Putative uncharacterized protein ATP6V1E1 |
| Synonyms
|
- SubName: cDNA FLJ51833, highly similar to Homo sapiens ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 (ATP6V1E1), transcript variant 2, mRNA
|
| Gene Name
| ATP6V1E1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in proton-transporting ATPase activity, rotational mechanism |
| Specific Function
| Not Available |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Component |
| proton-transporting two-sector atpase complex, catalytic domain |
| macromolecular complex |
| protein complex |
| Function |
| proton-transporting atpase activity, rotational mechanism |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| cation transmembrane transporter activity |
| inorganic cation transmembrane transporter activity |
| monovalent inorganic cation transmembrane transporter activity |
| hydrogen ion transmembrane transporter activity |
| transporter activity |
| Process |
| purine nucleotide metabolic process |
| purine nucleotide biosynthetic process |
| purine nucleoside triphosphate biosynthetic process |
| purine ribonucleoside triphosphate biosynthetic process |
| metabolic process |
| nitrogen compound metabolic process |
| cellular nitrogen compound metabolic process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
| nucleobase, nucleoside and nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| nucleotide metabolic process |
| atp synthesis coupled proton transport |
| atp biosynthetic process |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 22pter-q11.2|22q11.1 |
| SNPs
| ATP6V1E1 |
| Gene Sequence
|
>615 bp
ATGGCTCTCAGCGATGCTGACGTGCAAAAGCAGGCAGAAGAAGAGTTCAACATAGAGAAA
GGTCGGCTTGTGCAAACCCAAAGACTAAAGATTATGGAATATTATGAGAAGAAAGAGAAA
CAGATTGAGCAGCAGAAGAAAATTCAGATGTCCAATTTGATGAATCAAGCGAGACTCAAA
GTCCTCAGAGCAAGAGATGACCTTATCACAGACCTACTAAATGAAGCAAAACAGAGACTC
AGCAAGGTGGTAAAAGATACAACCAGGTACCAAGTGCTGCTGGATGGACTGGTTCTCCAG
GGTTTGTACCAGTTGCTGGAGCCCCGAATGATTGTTCGTTGCAGGAAACAAGATTTCCCT
CTGGTAAAGGCTGCAGTGCAGAAGGCAATTCCTATGTACAAAATTGCCACCAAAAACGAT
GTTGATGTCCAAATTGACCAGGAGTCCTACCTGCCTGAAGACATAGCTGGTGGAGTTGAG
ATCTATAATGGAGATCGTAAAATAAAGGTTTCCAACACCCTGGAAAGCCGGCTGGATCTC
ATAGCCCAGCAGATGATGCCAGAAGTCCGGGGAGCCTTGTTTGGTGCAAATGCCAACAGG
AAGTTTTTGGACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 204 |
| Molecular Weight
| 23587.2 |
| Theoretical pI
| 9.47 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Putative uncharacterized protein ATP6V1E1
MALSDADVQKQAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKIQMSNLMNQARLK
VLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEPRMIVRCRKQDFP
LVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVEIYNGDRKIKVSNTLESRLDL
IAQQMMPEVRGALFGANANRKFLD
|
| External Links |
|---|
| GenBank ID Protein
| 87159816 |
| UniProtKB/Swiss-Prot ID
| P36543 |
| UniProtKB/Swiss-Prot Entry Name
| A8MUE4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001039366.1 |
| GeneCard ID
| ATP6V1E1 |
| GenAtlas ID
| ATP6V1E1 |
| HGNC ID
| HGNC:857 |
| References |
|---|
| General References
| - Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al.: The DNA sequence of human chromosome 22. Nature. 1999 Dec 2;402(6761):489-95. [PubMed:10591208 ]
|
