Human Metabolome Database: Showing Protein Glycylpeptide N-tetradecanoyltransferase (HMDBP10650)

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Identification Biological properties Gene properties Protein properties External links References XML Show 1 metabolite

Identification

HMDB Protein ID

HMDBP10650

Secondary Accession Numbers

16887

Name

Glycylpeptide N-tetradecanoyltransferase

Synonyms

Not Available

Gene Name

NMT2

Protein Type

Enzyme

Biological Properties

General Function

Involved in glycylpeptide N-tetradecanoyltransferase activity

Specific Function

Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins

Pathways

Not Available

Reactions

Not Available

GO Classification

Function
catalytic activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
acyltransferase activity
n-acyltransferase activity
glycylpeptide n-tetradecanoyltransferase activity
Process
metabolic process
macromolecule metabolic process
protein amino acid lipidation
macromolecule modification
protein modification process
n-terminal protein lipidation
n-terminal protein myristoylation

Cellular Location

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

10p13

SNPs

NMT2

Gene Sequence

>1590 bp
ATGGCGGAGGACAGCGAGTCTGCGGCCAGCCAGCAGAGCCTGGAACTGGACGACCAGGAC
ACGTGCGGGATAGACGGGGACAATGAGGAGGAGACGGAGCACGCCAAAGGAAGTCCTGGA
GGGTATTTGGGAGCCAAAAAGAAAAAGAAGAAACAGAAGAGAAAAAAGGAGAAACCAAAT
TCCGGAGGCACCAAGTCAGACTCGGCATCTGATTCCCAGGAGATTAAAATTCAGCAGCCT
TCGAAACACAACACCATCTGGCAGCAGATTTCAGCGGGAGCAGCCATGGGTAGTGCTACT
ATGGAAGGTGAATGGACAGGCATGAGAAATGATCATAAGAATCCCAGTGTTCCAATGCAG
AAGTTGCAGGATATCCAGAGAGCAATGGAGCTGCTATCCGCATGCCAGGGCCCAGCCAGG
AACATTGATGAGGCTGCAAAGCACAGATACCAGTTTTGGGACACACAACCGGTACCAAAA
CTAGATGAAGTCATAACATCTCATGGTGCAATTGAACCAGATAAAGACAACGTACGCCAA
GAACCGTATTCTTTGCCACAGGGTTTTATGTGGGACACTTTAGACTTGAGTGATGCCGAA
GTGCTCAAGGAGTTATACACGTTGTTAAATGAGAATTACGTAGAAGATGATGACAATATG
TTCCGATTTGACTATTCACCCGAGTTCCTGTTGTGGGCTCTGCGTCCACCAGGCTGGCTC
CTGCAGTGGCACTGTGGGGTCAGAGTGTCTTCAAATAAAAAACTGGTCGGGTTCATAAGT
GCCATCCCAGCAAACATTCGGATTTATGACAGTGTGAAGAAGATGGTAGAAATCAACTTT
CTTTGTGTTCATAAGAAGTTGAGATCGAAACGGGTAGCCCCAGTGCTAATCCGAGAGATC
ACTAGAAGAGTGAACCTGGAAGGGATCTTCCAGGCTGTGTACACCGCGGGAGTGGTTCTT
CCTAAGCCCATAGCCACATGCAGATACTGGCATCGATCACTAAACCCCAGAAAATTGGTA
GAAGTGAAATTTTCTCACTTGAGTAGAAATATGACTTTACAGAGAACAATGAAGCTATAC
AGACTTCCAGATGTTACAAAGACTTCAGGTTTGAGACCAATGGAACCAAAAGATATCAAA
TCAGTTCGAGAATTAATCAACACTTACCTGAAGCAGTTTCATCTGGCTCCAGTGATGGAT
GAAGAGGAAGTAGCCCACTGGTTCCTCCCCCGGGAGCACATTATTGACACGTTTGTAGTG
GAGAGCCCCAACGGTAAACTGACTGATTTCCTGAGCTTCTATACGCTCCCCTCCACGGTG
ATGCACCACCCTGCTCACAAGAGCCTCAAAGCCGCCTACTCATTCTACAACATCCACACA
GAGACGCCCCTGCTGGACCTCATGAGCGACGCGCTCATCCTGGCTAAATCGAAAGGATTT
GATGTATTCAATGCACTGGATTTGATGGAAAATAAGACATTCTTGGAAAAACTCAAGTTT
GGTATAGGAGATGGCAATTTGCAGTATTACCTGTACAATTGGAGGTGTCCAGGTACAGAT
TCTGAAAAGGTTGGACTAGTACTACAATAG

Protein Properties

Number of Residues

529

Molecular Weight

60378.5

Theoretical pI

7.46

Pfam Domain Function

NMT (PF01233 )
NMT_C (PF02799 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>Glycylpeptide N-tetradecanoyltransferase
MAEDSESAASQQSLELDDQDTCGIDGDNEEETEHAKGSPGGYLGAKKKKKKQKRKKEKPN
SGGTKSDSASDSQEIKIQQPSKHNTIWQQISAGAAMGSATMEGEWTGMRNDHKNPSVPMQ
KLQDIQRAMELLSACQGPARNIDEAAKHRYQFWDTQPVPKLDEVITSHGAIEPDKDNVRQ
EPYSLPQGFMWDTLDLSDAEVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWL
LQWHCGVRVSSNKKLVGFISAIPANIRIYDSVKKMVEINFLCVHKKLRSKRVAPVLIREI
TRRVNLEGIFQAVYTAGVVLPKPIATCRYWHRSLNPRKLVEVKFSHLSRNMTLQRTMKLY
RLPDVTKTSGLRPMEPKDIKSVRELINTYLKQFHLAPVMDEEEVAHWFLPREHIIDTFVV
ESPNGKLTDFLSFYTLPSTVMHHPAHKSLKAAYSFYNIHTETPLLDLMSDALILAKSKGF
DVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ

External Links

GenBank ID Protein

55665859

UniProtKB/Swiss-Prot ID

Q5VUC7

UniProtKB/Swiss-Prot Entry Name

Q5VUC7_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AL590365

GeneCard ID