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HMDB0014947 | Tropicamide | 1508-75-4 | | C17H20N2O2 | 284.3529 284.152477894 | - Betz AJ, McLaughlin PJ, Burgos M, Weber SM, Salamone JD: The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors. Psychopharmacology (Berl). 2007 Oct;194(3):347-59. Epub 2007 Jun 27. [PubMed:17594079 ]
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HMDB0014520 | Trihexyphenidyl | 144-11-6 | | C20H31NO | 301.4662 301.240564619 | - Bognar IT, Altes U, Beinhauer C, Kessler I, Fuder H: A muscarinic receptor different from the M1, M2, M3 and M4 subtypes mediates the contraction of the rabbit iris sphincter. Naunyn Schmiedebergs Arch Pharmacol. 1992 Jun;345(6):611-8. [PubMed:1635586 ]
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HMDB0014648 | Tridihexethyl | 60-49-1 | | C21H36NO | 318.5166 318.279689779 | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
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HMDB0014339 | Tramadol | 27203-92-5 | | C16H25NO2 | 263.3752 263.188529049 | - Shiraishi M, Minami K, Uezono Y, Yanagihara N, Shigematsu A: Inhibition by tramadol of muscarinic receptor-induced responses in cultured adrenal medullary cells and in Xenopus laevis oocytes expressing cloned M1 receptors. J Pharmacol Exp Ther. 2001 Oct;299(1):255-60. [PubMed:11561087 ]
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HMDB0015479 | Tiotropium | 186691-13-4 | | C19H22NO4S2 | 392.512 392.099024577 | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
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HMDB0014486 | Terfenadine | 50679-08-8 | | C32H41NO2 | 471.6734 471.313729561 | - Yasuda SU, Yasuda RP: Affinities of brompheniramine, chlorpheniramine, and terfenadine at the five human muscarinic cholinergic receptor subtypes. Pharmacotherapy. 1999 Apr;19(4):447-51. [PubMed:10212017 ]
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HMDB0014347 | Succinylcholine | 306-40-1 | | C14H30N2O4 | 290.399 290.220557458 | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
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HMDB0014915 | Propiomazine | 362-29-8 | | C20H24N2OS | 340.482 340.16093409 | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
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HMDB0015202 | Promethazine | 60-87-7 | | C17H20N2S | 284.419 284.13471934 | - Golembiewski JA, O'Brien D: A systematic approach to the management of postoperative nausea and vomiting. J Perianesth Nurs. 2002 Dec;17(6):364-76. [PubMed:12476402 ]
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HMDB0013938 | Promazine 5-sulfoxide | | | C17H20N2OS | 300.418 300.129633962 | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
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HMDB0014531 | Procyclidine | 77-37-2 | | C19H29NO | 287.4397 287.224914555 | - Waelbroeck M, Camus J, Tastenoy M, Mutschler E, Strohmann C, Tacke R, Schjelderup L, Aasen A, Lambrecht G, Christophe J: Stereoselective interaction of procyclidine, hexahydro-difenidol, hexbutinol and oxyphencyclimine, and of related antagonists, with four muscarinic receptors. Eur J Pharmacol. 1992 Sep 1;227(1):33-42. [PubMed:1426023 ]
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HMDB0015431 | Pipecuronium | 68399-58-6 | | C35H62N4O4 | 602.8912 602.477106492 | - Karpati E, Biro K, Kukorelli T: [Investigation of neuromuscular blocking agents at Richter Ltd]. Acta Pharm Hung. 2002;72(1):37-48. [PubMed:12426786 ]
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HMDB0015217 | Pilocarpine | 54-71-7 | | C11H16N2O2 | 208.2569 208.121177766 | - Sykes DA, Dowling MR, Charlton SJ: Exploring the mechanism of agonist efficacy: a relationship between efficacy and agonist dissociation rate at the muscarinic M3 receptor. Mol Pharmacol. 2009 Sep;76(3):543-51. doi: 10.1124/mol.108.054452. Epub 2009 Jun 4. [PubMed:19498041 ]
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HMDB0014853 | Paroxetine | 61869-08-7 | | C19H20FNO3 | 329.3654 329.142721716 | - Cusack B, Nelson A, Richelson E: Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology (Berl). 1994 May;114(4):559-65. [PubMed:7855217 ]
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HMDB0015430 | Pancuronium | 15500-66-0 | | C35H60N2O4 | 572.8619 572.455308418 | - Milchert M, Spassov A, Meissner K, Nedeljkov V, Lehmann C, Wendt M, Loster BW, Mazurkiewicz-Janik M, Gedrange T, Pavlovic D: Skeletal muscle relaxants inhibit rat tracheal smooth muscle tone in vitro. J Physiol Pharmacol. 2009 Dec;60 Suppl 8:5-11. [PubMed:20400785 ]
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HMDB0014527 | Oxyphencyclimine | 125-53-1 | | C20H28N2O3 | 344.4479 344.209992772 | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
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HMDB0015195 | Oxybutynin | 5633-20-5 | | C22H31NO3 | 357.4864 357.230393863 | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
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HMDB0005012 | Olanzapine | 132539-06-1 | | C17H20N4S | 312.432 312.14086735 | Not Available |
HMDB0014680 | Nortriptyline | 72-69-5 | | C19H21N | 263.3767 263.167399677 | - Cusack B, Nelson A, Richelson E: Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology (Berl). 1994 May;114(4):559-65. [PubMed:7855217 ]
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HMDB0014760 | Nicardipine | 55985-32-5 | | C26H29N3O6 | 479.525 479.205635675 | - Thayer SA, Welcome M, Chhabra A, Fairhurst AS: Effects of dihydropyridine calcium channel blocking drugs on rat brain muscarinic and alpha-adrenergic receptors. Biochem Pharmacol. 1985 Jan 15;34(2):175-80. [PubMed:2981533 ]
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HMDB0013972 | N-Dealkylated tolterodine | | | C19H25NO | 283.4079 283.193614427 | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
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HMDB0015357 | Mivacurium | 106791-40-6 | | C58H80N2O14 | 1029.2608 1028.560955278 | - Habre W, Adamicza A, Lele E, Novak T, Sly PD, Petak F: The involvement of histaminic and muscarinic receptors in the bronchoconstriction induced by myorelaxant administration in sensitized rabbits. Anesth Analg. 2008 Dec;107(6):1899-906. doi: 10.1213/ane.0b013e318186587c. [PubMed:19020136 ]
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HMDB0014484 | Metixene | 4969-02-2 | | C20H23NS | 309.468 309.155120431 | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
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HMDB0014605 | Methylscopolamine | 155-41-9 | | C18H24NO4 | 318.392 318.169984677 | - Sykes DA, Dowling MR, Charlton SJ: Exploring the mechanism of agonist efficacy: a relationship between efficacy and agonist dissociation rate at the muscarinic M3 receptor. Mol Pharmacol. 2009 Sep;76(3):543-51. doi: 10.1124/mol.108.054452. Epub 2009 Jun 4. [PubMed:19498041 ]
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