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HMDB Protein ID HMDBP11607
Secondary Accession Numbers None
Name 1,5-anhydro-D-fructose reductase
  1. AF reductase
  2. Aldo-keto reductase family 1 member C-like protein 2
  3. Aldo-keto reductase family 1 member E2
  4. LoopADR
  5. Testis-specific protein
  6. hTSP
Gene Name AKR1E2
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro).
Pathways Not Available
1,5-Anhydrosorbitol + NADP → D-1,5-Anhydrofructose + NADPH details
GO Classification
Cellular Component
Molecular Function
1,5-anhydro-D-fructose reductase activity
Cellular Location Not Available
Gene Properties
Chromosome Location 10
Locus 10p15.1
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 36588.935
Theoretical pI 7.493
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>>gi|93277124|ref|NP_001035267.1| 1,5-anhydro-D-fructose reductase isoform 1 [Homo sapiens]
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q96JD6
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
General References Not Available