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Identification
HMDB Protein ID HMDBP11661
Secondary Accession Numbers None
Name Probable ATP-dependent RNA helicase DDX17
Synonyms
  1. DEAD box protein 17
  2. DEAD box protein p72
  3. RNA-dependent helicase p72
Gene Name DDX17
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function RNA-dependent ATPase activity. Involved in transcriptional regulation. Transcriptional coactivator for estrogen receptor ESR1. Increases ESR1 AF-1 domain-mediated transactivation. Synergizes with DDX5 and SRA1 RNA to activate MYOD1 transcriptional activity and probably involved in skeletal muscle differentiation. Required for zinc-finger antiviral protein ZC3HAV1-mediated mRNA degradation.
Pathways Not Available
Reactions
Adenosine triphosphate + Water → ADP + Phosphoric acid details
GO Classification
Biological Process
positive regulation of intracellular estrogen receptor signaling pathway
regulation of skeletal muscle cell differentiation
RNA processing
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-dependent
Cellular Component
nucleolus
nucleus
Molecular Function
RNA helicase activity
RNA-dependent ATPase activity
ATP binding
ATP-dependent helicase activity
estrogen receptor binding
transcription coactivator activity
RNA binding
Cellular Location Not Available
Gene Properties
Chromosome Location 22
Locus 22q13.1
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 80271.8
Theoretical pI 8.269
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>>gi|38201710|ref|NP_006377.2| probable ATP-dependent RNA helicase DDX17 isoform 1 [Homo sapiens]
MPTGFVAPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQ
ALPSPAIRAP
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q92841
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:2740
References
General References Not Available