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Identification
HMDB Protein ID HMDBP11738
Secondary Accession Numbers None
Name Fucose mutarotase
Synonyms Not Available
Gene Name FUOM
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Involved in the interconversion between alpha- and beta-L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O-glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes.
Pathways Not Available
Reactions
L-Fucose → beta-L-Fucose details
GO Classification
Biological Process
fucose metabolic process
Molecular Function
fucose binding
racemase and epimerase activity, acting on carbohydrates and derivatives
Cellular Location Not Available
Gene Properties
Chromosome Location 10
Locus 10q26.3
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 16764.555
Theoretical pI 5.581
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>>gi|148596947|ref|NP_001091953.1| fucose mutarotase isoform 1 [Homo sapiens]
MVALKGVPALLSPELLYALARMGHGDEIVLADLNFPASSICQCGPMEIRADGLGIPQLLE
AVLKLLPLDT
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID A2VDF0
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:24733
References
General References Not Available