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Identification |
HMDB Protein ID
| HMDBP11775 |
Secondary Accession Numbers
| None |
Name
| Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 4 |
Synonyms
|
- 3-hydroxyacyl-CoA dehydratase 4
- Protein tyrosine phosphatase-like protein PTPLAD2
- Protein-tyrosine phosphatase-like A domain-containing protein 2
- HACD4
|
Gene Name
| PTPLAD2 |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Responsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis.
|
Pathways
|
Not Available
|
Reactions
|
A very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] → a very-long-chain trans-2,3-dehydroacyl-[acyl-carrier protein] + Water |
details
|
|
GO Classification
|
Biological Process |
fatty acid biosynthetic process |
Cellular Component |
endoplasmic reticulum membrane |
integral to membrane |
Molecular Function |
lyase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 9 |
Locus
| 9p21.3 |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| Not Available |
Molecular Weight
| 27519.565 |
Theoretical pI
| 8.579 |
Pfam Domain Function
|
Not Available |
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>>gi|148226324|ref|NP_001010915.2| very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 4 [Homo sapiens]
MGPLALPAWLQPRYRKNAYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLV
MRLCQSVSLL
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q5VWC8 |
UniProtKB/Swiss-Prot Entry Name
| Not Available |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| HGNC:20920 |
References |
General References
| Not Available |