| Identification |
|---|
| HMDB Protein ID
| HMDBP11788 |
| Secondary Accession Numbers
| None |
| Name
| Heparan sulfate glucosamine 3-O-sulfotransferase 6 |
| Synonyms
|
- Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6
- 3-OST-6
- Heparan sulfate 3-O-sulfotransferase 6
- h3-OST-6
|
| Gene Name
| HS3ST6 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
|
| Pathways
|
Not Available
|
| Reactions
|
| Phosphoadenosine phosphosulfate + [heparan sulfate]-glucosamine → Adenosine 3',5'-diphosphate + [heparan sulfate]-glucosamine 3-sulfate |
details
|
|
| GO Classification
|
| Biological Process |
| small molecule metabolic process |
| glycosaminoglycan biosynthetic process |
| carbohydrate metabolic process |
| Cellular Component |
| integral to membrane |
| Golgi membrane |
| Molecular Function |
| [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q96QI5 |
| UniProtKB/Swiss-Prot Entry Name
| Not Available |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:14178 |
| References |
|---|
| General References
| Not Available |
