Identification |
HMDB Protein ID
| HMDBP11834 |
Secondary Accession Numbers
| None |
Name
| Mitochondrial pyruvate carrier 1 |
Synonyms
|
- Brain protein 44-like protein
|
Gene Name
| MPC1 |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| Mediates the uptake of pyruvate into mitochondria.
|
Pathways
|
- 2-ketoglutarate dehydrogenase complex deficiency
- Citric Acid Cycle
- Congenital lactic acidosis
- Fructose-1,6-diphosphatase deficiency
- Fumarase deficiency
- Gluconeogenesis
- Glutaminolysis and Cancer
- Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease
- Glycogenosis, Type IA. Von gierke disease
- Glycogenosis, Type IB
- Glycogenosis, Type IC
- Mitochondrial complex II deficiency
- Phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1)
- Pyruvate dehydrogenase deficiency (E2)
- Pyruvate dehydrogenase deficiency (E3)
- The oncogenic action of 2-hydroxyglutarate
- The oncogenic action of D-2-hydroxyglutarate in Hydroxygluaricaciduria
- The Oncogenic Action of Fumarate
- The oncogenic action of L-2-hydroxyglutarate in Hydroxygluaricaciduria
- The Oncogenic Action of Succinate
- Transfer of Acetyl Groups into Mitochondria
- Triosephosphate isomerase
- Warburg Effect
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
transport |
Cellular Component |
integral to membrane |
mitochondrial inner membrane |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 6 |
Locus
| 6q27 |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| Not Available |
Molecular Weight
| 12347.37 |
Theoretical pI
| 9.615 |
Pfam Domain Function
|
Not Available |
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>>gi|7706369|ref|NP_057182.1| mitochondrial pyruvate carrier 1 isoform 1 [Homo sapiens]
MAGALVRKAADYVRSKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALC
CYSLTFMRFA
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q9Y5U8 |
UniProtKB/Swiss-Prot Entry Name
| Not Available |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| HGNC:21606 |
References |
General References
| Not Available |