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Identification
HMDB Protein ID HMDBP11837
Secondary Accession Numbers None
Name Myotubularin-related protein 2
Synonyms Not Available
Gene Name MTMR2
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate.
Pathways
  • Fructose and mannose metabolism
Reactions
NADP + Water → Phosphoric acid + NAD details
Beta-D-Fructose 2-phosphate + Water → D-Fructose + Phosphoric acid details
N-Acetylmannosamine + Phosphoric acid → N-Acetyl-D-mannosamine 6-phosphate + Water details
GO Classification
Biological Process
small molecule metabolic process
phosphatidylinositol biosynthetic process
dendritic spine maintenance
negative regulation of excitatory postsynaptic membrane potential
negative regulation of receptor catabolic process
negative regulation of receptor internalization
positive regulation of early endosome to late endosome transport
regulation of excitatory postsynaptic membrane potential
phosphatidylinositol dephosphorylation
protein tetramerization
inositol phosphate dephosphorylation
peptidyl-tyrosine dephosphorylation
Cellular Component
cytosol
synaptic membrane
vacuolar membrane
nucleus
early endosome membrane
synaptic vesicle
axon
postsynaptic density
Molecular Function
protein tyrosine/serine/threonine phosphatase activity
protein tyrosine phosphatase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight Not Available
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q13614
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:7450
References
General References Not Available