You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Human Metabolome Database.
Identification
HMDB Protein ID HMDBP11838
Secondary Accession Numbers None
Name Myotubularin-related protein 6
Synonyms Not Available
Gene Name MTMR6
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.
Pathways
  • Fructose and mannose metabolism
Reactions
NADP + Water → Phosphoric acid + NAD details
Beta-D-Fructose 2-phosphate + Water → D-Fructose + Phosphoric acid details
N-Acetylmannosamine + Phosphoric acid → N-Acetyl-D-mannosamine 6-phosphate + Water details
GO Classification
Biological Process
small molecule metabolic process
phosphatidylinositol biosynthetic process
Cellular Component
cytosol
nuclear envelope
Molecular Function
protein serine/threonine phosphatase activity
calcium-activated potassium channel activity
protein tyrosine phosphatase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight Not Available
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9Y217
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:7453
References
General References Not Available