Human Metabolome Database: Showing Protein Vacuolar protein sorting-associated protein 29 (HMDBP12004)

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Identification Biological properties Gene properties Protein properties External links References XML Show 2 metabolites

Identification

HMDB Protein ID

HMDBP12004

Secondary Accession Numbers

None

Name

Vacuolar protein sorting-associated protein 29

Synonyms

hVPS29
PEP11 homolog
Vesicle protein sorting 29

Gene Name

VPS29

Protein Type

Unknown

Biological Properties

General Function

Not Available

Specific Function

Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).

Pathways

Not Available

Reactions

O-phospho-L(or D)-serine + Water → L(or D)-serine + Phosphate

details

GO Classification

Biological Process
protein transport
Cellular Component
endosome membrane
endosome
Molecular Function
metal ion binding
phosphoserine phosphatase activity

Cellular Location

Not Available

Gene Properties

Chromosome Location

Locus

12q24

SNPs

Not Available

Gene Sequence

Not Available

Protein Properties

Number of Residues

Not Available

Molecular Weight

20505.595

Theoretical pI

6.791

Pfam Domain Function

Metallophos_2 (PF12850 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>>gi|7706441|ref|NP_057310.1| vacuolar protein sorting-associated protein 29 isoform 1 [Homo sapiens]
MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVR
GDFDENLNYP

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

Q9UBQ0

UniProtKB/Swiss-Prot Entry Name

Not Available

PDB IDs