Accession NumberHMDB06244
Common_Name12 hydroxy arachidonic acid
DescriptionArachidonic acid is generated by Phospholipase A2 (PLA2) from neural membrane phospholipids.This metabolite has a variety of physiological effects by itself and also is substrates for the synthesis of more potent lipid mediators such as eicosanoids, platelet activating factor, and 4-hydroxynonenal (4-HNE). (PMID: 16684969) The active metabolites of arachidonic acid,Eicosanoids, (AA), play an important role in the regulation of renal haemodynamics and glomerular filtration. Cytochromes P450 (P450s) are known to oxidize arachidonic acid to the physiologically active molecules hydroxyeicosatetraenoic acids (HETEs) and epoxyeicosatrienoic acids (EETs), which play important roles in blood pressure regulation and inflammation. (PMID: 17272674)
Chemical_IUPAC_NameNot Available
Chemical FormulaC20H32O3
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Predicted 1H NMR SpectrumDownload
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Predicted 13C NMR PeaklistDownload
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