Accession NumberHMDB04701
Common_Name9,10-epoxyoctadecenoic acid
Description9,10-epoxyoctadecenoic acid (9,10-EOA) is a peroxidation product of linoleic acid (LA). 9,10-EOA is a naturally occurring component of oxidized low density lipoprotein (LDL), the level of which increases with aging, atherosclerosis, and rheumatoid arthritis, perhaps due to an increase in 15-lipoxygenase and free oxygen radicals. 9,10-EOA is a proliferator-activated receptors (PPAR) gamma2 ligand, that is antiosteogenic without stimulating adipocyte differentiation. Studies in dogs suggest that 9,10-EOA has toxic cardiovascular effects. (PMID: 12665667, 12021203, 10667371)
Chemical_IUPAC_Name8-[3-[(Z)-oct-2-enyl]oxiran-2-yl]octanoic acid
Chemical FormulaC18H32O3
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