Accession NumberHMDB06780
Common_NameTriiodo thyronine
DescriptionTriiodothyronine, C15H12I3NO4, also known as T3, is a thyroid hormone. Thyroid-stimulating hormone (TSH) activates the production of tetraiodothyronine (T4) and T3. This process is under regulation. In the hypothalamus, T4 is converted to T3. TSH is inhibited mainly by T3. The thyroid gland releases greater amounts of T4 than T3, so plasma concentration of T4 are 40-fold higher than those T3. Most the circulating T3 is formed peripherally by deiodination of T4 (85%), a process that involves the removal of iodine from carbon 5 on the outer ring of T4. Thus, T4 acts as prohormone for T3. This thyroid hormone is similar to thyroxine but with one fewer iodine atom per molecule. In addition, T3 exhibits greater activity and is produced in smaller quantity.It is the most powerful thyroid hormone, and affects almost every process in the body, including body temperature, growth, and heart rate.(Wikipedia)
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Chemical FormulaC15H12I3NO4
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