Accession NumberHMDB01908
Common_NameEganoprost
Description19(R)-hydroxy-PGE2 (19-OH PGE2) is a selective prostanoid EP2-receptor agonist; it doesn't stimulate FP-receptors, and is devoid of activity at thromboxane A2, prostaglandin D2 and prostacyclin sensitive receptors. 19-OH PGE2 is formed in large quantities from PGE2 in human seminal plasma. PGE2 is the most common and most biologically active of the mammalian prostaglandins. It has important effects in labour and also stimulates osteoblasts to release factors which stimulate bone resorption by osteoclasts (a type of bone cell that removes bone tissue by removing the bone's mineralized matrix). (PMID: 16978535, 8248550, 817207)
Chemical_IUPAC_Name(Z)-7-[(1R,2R,3R)-2-[(E,3S,7R)-3,7-dihydroxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoic acid
Chemical FormulaC20H32O6
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Predicted 1H NMR SpectrumDownload
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Predicted 13C NMR PeaklistDownload
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