Accession NumberHMDB01028
Common_Name25-Azacholesterol
Description25-Azacholesterol has potent hypocholesterolemic activity. (PMID 14287266) It specifically inhibits cholesterol side-chain cleavage resulting in a decrease in steroid hormone production (PMID 5165491). Azasteroids may be membrane effectors which, in the case of mitochondria, lead to changes in adenosine triphosphate levels and(or) dehydrogenase activity. Their effects on sterol metabolism, therefore, may be of secondary consideration. (PMID 994744) 25-azacholesterol can induce a myotonic state in muscles. (PMID 5009506)
Chemical_IUPAC_Name(3S,8S,9R,10S,13R,14R,17S)-17-[(2R)-5-dimethylaminopentan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Chemical FormulaC26H45NO
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Predicted 1H NMR SpectrumDownload
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Predicted 13C NMR PeaklistDownload
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