Accession NumberHMDB04706
Common_Name8(R)-hydroperoxylinoleic acid
Description8(R)-hydroperoxylinoleic acid (8(R)-EPODE) is an oxidized product of linoleic acid. Oxidized lipids such as 8(R)-HPODE can decrease cellular proteoglycan metabolism in endothelial monolayers and alter mRNA levels of major specific proteoglycans in a concentration-dependent manner. This may have implications in lipid-mediated disruption of endothelial barrier function and atherosclerosis. (PMID: 8645361, 9507987)
Chemical_IUPAC_Name(8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoic acid
Chemical FormulaC18H32O4
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Predicted 1H NMR SpectrumDownload
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Predicted 13C NMR PeaklistDownload
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