Accession Number | HMDB04698 |
Common_Name | 12(R)-HETE |
Description | 12(R)-HETE is a naturally occurring hydroxyeicosatetraenoic acid eicosanoid that has been isolated from several tissues in mammals. Human and bovine corneal epithelial cytochrome P450 convert arachidonic acid to 12(R)-HETE, a metabolite with inflammatory properties including vasodilatation and breakdown of the blood-aqueous barrier. Increased amounts of 12(R)-HETE are found in the lesional skin of patients with the skin disease psoriasis when compared to clinically normal skin. 12(R)-HETE is a chemoattractant for human polymorphonuclear leucocytes in vitro. (PMID: 1709873, 3707572, 3317516) |
Chemical_IUPAC_Name | (5Z,8Z,10E,12R,14Z)-12-hydroxyicosa-5,8,10,14-tetraenoic acid |
Chemical Formula | C20H32O3 |
Sample Concentration | Not Available |
Mass Value | Not Available |
Mass Unit | Not Available |
Manufacturer | Not Available |
Analyzer | Not Available |
Delivery | Not Available |
Ionization | Not Available |
Predicted 1H NMR Spectrum | Download |
Predicted 1H NMR Peaklist | Download |
Predicted 13C NMR Spectrum | Download |
Predicted 13C NMR Peaklist | Download |
Sample Concentration | Not Available |
Mass Value | Not Available |
Mass Unit | Not Available |
Manufacturer | Not Available |
Frequency | Not Available |
1H NMR Spectrum | Not Available |
Sample Concentration | Not Available |
Mass Value | Not Available |
Mass Unit | Not Available |
Manufacturer | Not Available |
Frequency | Not Available |
13C NMR Spectrum | Not Available |
Low Energy Voltage | Not Available |
Low Energy Spectrum | Not Available |
Low Energy Peaklist | Not Available |
Medium Energy Spectrum | Not Available |
Hight Energy Spectrum | Not Available |