Accession NumberHMDB05045
Common_Name15S-hydroxyeicosatrienoic acid
Description15S-hydroxyeicosatrienoic acid (15S-HETrE) is the in vivo metabolite of gamma-linolenic acid, a polyunsaturated fatty acid that have been reported to modulate arachidonic acid (AA) metabolism and tumorigenesis. 15S-HETrE suppress cyclooxygenase-2 (COX-2) over expression and/or Prostaglandin E2 (PGE2) biosynthesis (PMID 15197770), and inhibits [(3)H]thymidine uptake in parallel with the upregulation of peroxisome proliferator-activated receptor-gamma expression (a growth modulating nuclear receptor, PPARgamma). (PMID 12445673)
Chemical_IUPAC_Name(8Z,11Z,13E,15S)-15-hydroxyicosa-8,11,13-trienoic acid
Chemical FormulaC20H34O3
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Predicted 1H NMR SpectrumDownload
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Predicted 13C NMR PeaklistDownload
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