Accession NumberHMDB03929
Common_Name5-Aminoimidazole
DescriptionBecause of its ability to mimic a low energy status of the cell, the cell-permeable nucleoside 5-aminoimidazole-4-carboxamide (AICA) riboside was proposed as an antineoplastic agent switching off major energy-consuming processes associated with the malignant phenotype (lipid production, DNA synthesis, cell proliferation, cell migration, etc.). Key to the antineoplastic action of AICA riboside is its conversion to ZMP, an AMP mimetic that at high concentrations activates the AMP-activated protein kinase (AMPK). (PMID: 16985054)
Chemical_IUPAC_Name3H-imidazol-4-amine
Chemical FormulaC3H5N3
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Predicted 13C NMR PeaklistDownload
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