Accession NumberHMDB02752
Common_NameProstaglandin A2
DescriptionProduced by the seminal vessicals: Prostaglandins are a group of lipid compounds that are derived enzymatically from fattyacids. Technically a hormone, the prostanoid class of fatty acid derivatives is a subclass of eicosanoids. Prostaglandin A is cyclopentenone and endogenous metabolite derived from arachidonic acid. Exhibits potent cellular anti-proliferative activity in vivo and in vitro. Excess PGA2 causes an accumulation in both S and G2/M, and a marked decrease in G1. As well there is an increase in DNA content preceeding the G0/G1 peak (indicative of apoptic body formation) mediated by changes in expression levels of Bax and Bcl-2.
Chemical_IUPAC_Name(5Z,13E,15S)15-hydroxy-9-oxo-prosta-5,10,13-trien-1-oic acid
Chemical FormulaC20H30O4
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Predicted 1H NMR SpectrumDownload
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Predicted 13C NMR PeaklistDownload
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