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Record Information
Version5.0
StatusDetected and Quantified
Creation Date2005-11-16 15:48:42 UTC
Update Date2021-09-14 15:38:58 UTC
HMDB IDHMDB0001401
Secondary Accession Numbers
  • HMDB0001549
  • HMDB0006793
  • HMDB01401
  • HMDB01549
  • HMDB06793
Metabolite Identification
Common NameGlucose 6-phosphate
DescriptionGlucose 6-phosphate (G6P, sometimes called the Robison ester) is a glucose sugar phosphorylated at the hydroxy group on carbon 6. Glucose 6-phosphate (G6P) has two anomers: the alpha anomer and the beta anomer. Glucose 6-phosphate is an ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose 6-phosphate (Stedman, 26th ed). When glucose enters a cell, it is immediately phosphorylated to G6P. This is catalyzed with hexokinase enzymes, thus consuming one ATP. A major reason for immediate phosphorylation of the glucose is so that it cannot diffuse out of the cell. The phosphorylation adds a charged group so the G6P cannot easily cross cell membranes. G6P can travel down two metabolic pathways: glycolysis and the pentose phosphate pathway. In addition to the metabolic pathways, G6P can also be stored as glycogen in the liver if blood glucose levels are high. If the body needs energy or carbon skeletons for syntheses, G6P can be isomerized to fructose 6-phosphate and then phosphorylated to fructose 1,6-bisphosphate. Note, the molecule now has 2 phosphoryl groups attached. The addition of the 2nd phosphoryl group is an irreversible step, so once this happens G6P will enter glycolysis and be turned into pyruvate (ATP production occurs). If blood glucose levels are high, the body needs a way to store the excess glucose. After being converted to G6P, phosphoglucose mutase (an isomerase) can turn the molecule into glucose 1-phosphate. Glucose 1-phosphate can then be combined with uridine triphosphate (UTP) to form UDP-glucose. This reaction is driven by the hydrolysis of pyrophosphate that is released in the reaction. Now, the activated UDP-glucose can add to a growing glycogen molecule with the help of glycogen synthase. This is a very efficient storage mechanism for glucose since it costs the body only 1 ATP to store the 1 glucose molecule and virtually no energy to remove it from storage. It is important to note that glucose 6-phosphate is an allosteric activator of glycogen synthase, which makes sense because when the level of glucose is high the body should store the excess glucose as glycogen. On the other hand, glycogen synthase is inhibited when it is phosphorylated by protein kinase during times of high stress or low blood glucose levels.
Structure
Data?1582752198
Synonyms
ValueSource
6-O-Phosphono-D-glucopyranoseChEBI
D-Glucose 6-phosphateChEBI
GLC6pChEBI
Robison esterChEBI
D-Glucose 6-phosphoric acidGenerator
Glucose 6-phosphoric acidGenerator
a-D-Glucose 6- phosphateHMDB
alpha-D-Glucose 6- phosphateHMDB
alpha-D-Glucose 6-phosphateHMDB
alpha-D-Hexose 6-phosphateHMDB
D(+)-Glucopyranose 6-phosphateHMDB
D-Glucose-6-dihydrogen phosphateHMDB
D-Hexose 6-phosphateHMDB
Glucose-6-phosphateHMDB
Glucose 6-phosphateKEGG
D-Glucopyranose 6-phosphoric acidGenerator
Chemical FormulaC6H13O9P
Average Molecular Weight260.1358
Monoisotopic Molecular Weight260.029718526
IUPAC Name{[(2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid
Traditional Nameglucose 6-phosphate
CAS Registry Number56-73-5
SMILES
OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O
InChI Identifier
InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6?/m1/s1
InChI KeyNBSCHQHZLSJFNQ-GASJEMHNSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups.
KingdomOrganic compounds
Super ClassOrganic oxygen compounds
ClassOrganooxygen compounds
Sub ClassCarbohydrates and carbohydrate conjugates
Direct ParentHexose phosphates
Alternative Parents
Substituents
  • Hexose phosphate
  • Monosaccharide phosphate
  • Monoalkyl phosphate
  • Organic phosphoric acid derivative
  • Alkyl phosphate
  • Oxane
  • Phosphoric acid ester
  • Hemiacetal
  • Secondary alcohol
  • Oxacycle
  • Organoheterocyclic compound
  • Polyol
  • Hydrocarbon derivative
  • Alcohol
  • Organic oxide
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External Descriptors
Ontology
Physiological effectNot Available
Disposition
Biological locationSource
Process
Naturally occurring process
Role
Physical Properties
StateLiquid
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Experimental Chromatographic Properties

Experimental Collision Cross Sections

Adduct TypeData SourceCCS Value (Å2)Reference
[M-H]-Astarita_neg143.330932474
[M-H]-Not Available146.5http://allccs.zhulab.cn/database/detail?ID=AllCCS00000421
Predicted Molecular Properties
PropertyValueSource
Water Solubility31.4 g/LALOGPS
logP-2.1ALOGPS
logP-3.1ChemAxon
logS-0.92ALOGPS
pKa (Strongest Acidic)1.22ChemAxon
pKa (Strongest Basic)-3.6ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count8ChemAxon
Hydrogen Donor Count6ChemAxon
Polar Surface Area156.91 ŲChemAxon
Rotatable Bond Count3ChemAxon
Refractivity46.8 m³·mol⁻¹ChemAxon
Polarizability21 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DarkChem[M+H]+160.11531661259
DarkChem[M-H]-153.19831661259
AllCCS[M+H]+156.31632859911
AllCCS[M-H]-147.16332859911
DeepCCS[M+H]+143.87330932474
DeepCCS[M-H]-141.47830932474
DeepCCS[M-2H]-175.8830932474
DeepCCS[M+Na]+150.95830932474
AllCCS[M+H]+156.332859911
AllCCS[M+H-H2O]+152.832859911
AllCCS[M+NH4]+159.632859911
AllCCS[M+Na]+160.532859911
AllCCS[M-H]-147.232859911
AllCCS[M+Na-2H]-147.532859911
AllCCS[M+HCOO]-147.932859911

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
Glucose 6-phosphateOC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O3460.7Standard polar33892256
Glucose 6-phosphateOC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O2090.2Standard non polar33892256
Glucose 6-phosphateOC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O2249.8Semi standard non polar33892256

Derivatized

Derivative Name / StructureSMILESKovats RI ValueColumn TypeReference
Glucose 6-phosphate,1TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@H]1O2152.3Semi standard non polar33892256
Glucose 6-phosphate,1TMS,isomer #2C[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O)OC(O)[C@H](O)[C@H]1O2115.4Semi standard non polar33892256
Glucose 6-phosphate,1TMS,isomer #3C[Si](C)(C)O[C@@H]1[C@@H](O)C(O)O[C@H](COP(=O)(O)O)[C@H]1O2129.5Semi standard non polar33892256
Glucose 6-phosphate,1TMS,isomer #4C[Si](C)(C)O[C@H]1C(O)O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O2157.5Semi standard non polar33892256
Glucose 6-phosphate,1TMS,isomer #5C[Si](C)(C)OP(=O)(O)OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O2267.7Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@H](O)[C@H]1O2113.2Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #10C[Si](C)(C)O[C@H]1C(O)O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@@H]1O2261.3Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #11C[Si](C)(C)OP(=O)(OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O)O[Si](C)(C)C2268.5Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #2C[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O[Si](C)(C)C)[C@H]1O2113.1Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #3C[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@H]1O[Si](C)(C)C2134.4Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #4C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@H](O)[C@H]1O2242.9Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #5C[Si](C)(C)O[C@H]1[C@H](O)[C@@H](O[Si](C)(C)C)C(O)O[C@@H]1COP(=O)(O)O2126.0Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #6C[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O)OC(O)[C@H](O)[C@H]1O[Si](C)(C)C2081.9Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #7C[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O[Si](C)(C)C)OC(O)[C@H](O)[C@H]1O2205.8Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #8C[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C)C(O)O[C@H](COP(=O)(O)O)[C@H]1O2127.9Semi standard non polar33892256
Glucose 6-phosphate,2TMS,isomer #9C[Si](C)(C)O[C@@H]1[C@@H](O)C(O)O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@H]1O2225.2Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O2118.7Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #10C[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O[Si](C)(C)C)OC(O)[C@H](O)[C@H]1O[Si](C)(C)C2153.4Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #11C[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)OC(O)[C@H](O)[C@H]1O2179.1Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #12C[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C)C(O)O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@H]1O2198.6Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #13C[Si](C)(C)O[C@@H]1[C@@H](O)C(O)O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@H]1O2185.6Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #14C[Si](C)(C)O[C@H]1C(O)O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@@H]1O2219.2Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #2C[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C2115.7Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #3C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@H]1O2167.8Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #4C[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2127.6Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #5C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@H]1O2182.5Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #6C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@H](O)[C@H]1O[Si](C)(C)C2180.9Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #7C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O)[C@H]1O2177.3Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #8C[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C)C(O)O[C@H](COP(=O)(O)O)[C@H]1O[Si](C)(C)C2137.2Semi standard non polar33892256
Glucose 6-phosphate,3TMS,isomer #9C[Si](C)(C)O[C@H]1[C@H](O)[C@@H](O[Si](C)(C)C)C(O)O[C@@H]1COP(=O)(O)O[Si](C)(C)C2200.6Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2149.6Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #10C[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)OC(O)[C@H](O)[C@H]1O[Si](C)(C)C2211.6Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #11C[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C)C(O)O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@H]1O2253.7Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #2C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O2203.2Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #3C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C2211.9Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #4C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@H]1O2203.7Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #5C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2215.6Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #6C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@H]1O2230.7Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #7C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O)[C@H]1O[Si](C)(C)C2185.4Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #8C[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C)C(O)O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2237.8Semi standard non polar33892256
Glucose 6-phosphate,4TMS,isomer #9C[Si](C)(C)O[C@H]1[C@H](O)[C@@H](O[Si](C)(C)C)C(O)O[C@@H]1COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C2258.2Semi standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2236.6Semi standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2242.3Standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2583.2Standard polar33892256
Glucose 6-phosphate,5TMS,isomer #2C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O2255.4Semi standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #2C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O2270.8Standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #2C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O2487.0Standard polar33892256
Glucose 6-phosphate,5TMS,isomer #3C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C2274.3Semi standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #3C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C2293.5Standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #3C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C2538.7Standard polar33892256
Glucose 6-phosphate,5TMS,isomer #4C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2268.9Semi standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #4C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2268.7Standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #4C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2499.5Standard polar33892256
Glucose 6-phosphate,5TMS,isomer #5C[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C)C(O)O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2277.1Semi standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #5C[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C)C(O)O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2267.0Standard non polar33892256
Glucose 6-phosphate,5TMS,isomer #5C[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C)C(O)O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2462.1Standard polar33892256
Glucose 6-phosphate,6TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2288.9Semi standard non polar33892256
Glucose 6-phosphate,6TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2293.9Standard non polar33892256
Glucose 6-phosphate,6TMS,isomer #1C[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C2407.7Standard polar33892256
Glucose 6-phosphate,1TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@H]1O2395.5Semi standard non polar33892256
Glucose 6-phosphate,1TBDMS,isomer #2CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O)OC(O)[C@H](O)[C@H]1O2398.4Semi standard non polar33892256
Glucose 6-phosphate,1TBDMS,isomer #3CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O)C(O)O[C@H](COP(=O)(O)O)[C@H]1O2412.8Semi standard non polar33892256
Glucose 6-phosphate,1TBDMS,isomer #4CC(C)(C)[Si](C)(C)O[C@H]1C(O)O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O2432.0Semi standard non polar33892256
Glucose 6-phosphate,1TBDMS,isomer #5CC(C)(C)[Si](C)(C)OP(=O)(O)OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O2523.1Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O2530.7Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #10CC(C)(C)[Si](C)(C)O[C@H]1C(O)O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O2703.8Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #11CC(C)(C)[Si](C)(C)OP(=O)(OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O)O[Si](C)(C)C(C)(C)C2740.9Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O2533.8Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #3CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C2535.5Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #4CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O)[C@H]1O2662.5Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #5CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@@H]1COP(=O)(O)O2570.9Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #6CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O)OC(O)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C2536.1Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #7CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)OC(O)[C@H](O)[C@H]1O2662.0Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #8CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@H](COP(=O)(O)O)[C@H]1O2569.3Semi standard non polar33892256
Glucose 6-phosphate,2TBDMS,isomer #9CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O)C(O)O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@H]1O2673.0Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O2742.9Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #10CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)OC(O)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C2817.6Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #11CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)OC(O)[C@H](O)[C@H]1O2845.7Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #12CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@H]1O2848.6Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #13CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O)C(O)O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H]1O2848.2Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #14CC(C)(C)[Si](C)(C)O[C@H]1C(O)O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]1O2883.1Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C2733.6Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #3CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O2795.2Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #4CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C2753.6Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #5CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O2799.9Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #6CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C2798.7Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #7CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O)[C@H]1O2831.0Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #8CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@H](COP(=O)(O)O)[C@H]1O[Si](C)(C)C(C)(C)C2790.2Semi standard non polar33892256
Glucose 6-phosphate,3TBDMS,isomer #9CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@@H]1COP(=O)(O)O[Si](C)(C)C(C)(C)C2844.5Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C2982.3Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #10CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)OC(O)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C3023.1Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #11CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H]1O3066.5Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O2989.1Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #3CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C3000.9Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #4CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O2999.6Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #5CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C3013.8Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #6CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O3011.1Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #7CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C3017.7Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #8CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C3054.8Semi standard non polar33892256
Glucose 6-phosphate,4TBDMS,isomer #9CC(C)(C)[Si](C)(C)O[C@H]1[C@H](O)[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@@H]1COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C3070.2Semi standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C3237.9Semi standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C3137.6Standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #1CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C3009.2Standard polar33892256
Glucose 6-phosphate,5TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O3214.7Semi standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O3130.3Standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #2CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O2948.7Standard polar33892256
Glucose 6-phosphate,5TBDMS,isomer #3CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C3228.7Semi standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #3CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C3159.5Standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #3CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@H]1O[Si](C)(C)C(C)(C)C2972.5Standard polar33892256
Glucose 6-phosphate,5TBDMS,isomer #4CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C3232.7Semi standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #4CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C3123.7Standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #4CC(C)(C)[Si](C)(C)OC1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C2957.1Standard polar33892256
Glucose 6-phosphate,5TBDMS,isomer #5CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C3275.1Semi standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #5CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C3139.9Standard non polar33892256
Glucose 6-phosphate,5TBDMS,isomer #5CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)C(O)O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C2929.4Standard polar33892256
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (6 TMS)splash10-000b-1932000000-59f4881b86595037d0132014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (6 TMS)splash10-0f7t-1933000000-4894135f21c21c3694282014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (6 TMS; 1 MEOX)splash10-00di-9522000000-81266970683faa1f2aaf2014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (6 TMS; 1 MEOX)splash10-00di-9412000000-2f2a0e772025b48bf6f32014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-MS (1 MEOX; 6 TMS)splash10-000j-1956000000-692b4df2b9c16f6a780c2014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-MS (1 MEOX; 6 TMS)splash10-000i-1957000000-bd94955ffc1474153a482014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-MS (6 TMS)splash10-0v0a-0596000000-676527ddfc1d596e78f82014-06-16HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-EI-TOF (Non-derivatized)splash10-000b-1932000000-59f4881b86595037d0132017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-EI-TOF (Non-derivatized)splash10-0f7t-1933000000-4894135f21c21c3694282017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-EI-TOF (Non-derivatized)splash10-00di-9522000000-81266970683faa1f2aaf2017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-EI-TOF (Non-derivatized)splash10-00di-9412000000-2f2a0e772025b48bf6f32017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-MS (Non-derivatized)splash10-000j-1956000000-692b4df2b9c16f6a780c2017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-MS (Non-derivatized)splash10-000i-1957000000-bd94955ffc1474153a482017-09-12HMDB team, MONA, MassBankView Spectrum
Experimental GC-MSGC-MS Spectrum - Glucose 6-phosphate GC-MS (Non-derivatized)splash10-0v0a-0596000000-676527ddfc1d596e78f82017-09-12HMDB team, MONA, MassBankView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Glucose 6-phosphate GC-MS (Non-derivatized) - 70eV, Positivesplash10-0005-9740000000-a6e81224fb97751dc2e62016-09-22Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Glucose 6-phosphate GC-MS (4 TMS) - 70eV, Positivesplash10-001i-6252790000-ef5662fb1886367e07f22017-10-06Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Glucose 6-phosphate GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Glucose 6-phosphate GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate Quattro_QQQ 10V, N/A-QTOF (Annotated)splash10-03di-0090000000-5653def80d1b5ff0eebb2012-07-24HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate Quattro_QQQ 25V, N/A-QTOF (Annotated)splash10-000b-9200000000-66741d773ac31b3476252012-07-24HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate Quattro_QQQ 40V, N/A-QTOF (Annotated)splash10-000t-9000000000-068809fcfaff0d387e6b2012-07-24HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative-QTOFsplash10-0a4i-1090000000-d6e539d78b38c01dafea2012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative-QTOFsplash10-0002-9210000000-8b9ff1c5095f48a81fef2012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative-QTOFsplash10-0002-9000000000-f6e1147852f75db4c0a42012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative-QTOFsplash10-002b-9000000000-1c52fd659f8a2b795e512012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative-QTOFsplash10-004i-9000000000-d3f6a05e18ea6d56c56d2012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive-QTOFsplash10-0006-0890000000-5f3047c92c970dfe69272012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive-QTOFsplash10-004i-0900000000-b84eb7685667fa7ee85e2012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive-QTOFsplash10-004i-2900000000-d4a0d51bb6e2da28533a2012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive-QTOFsplash10-004i-6900000000-dfb5bcbd9a7439c323522012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive-QTOFsplash10-03gi-9600000000-a0922c82e185f6b5aa672012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positive-QTOFsplash10-0006-0290000000-7ac7b397c52f29cd38222012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positive-QTOFsplash10-052b-6590000000-5cdbc23378480ac55c4f2012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-IT (LC/MSD Trap XCT, Agilent Technologies) , Positive-QTOFsplash10-004i-1900000000-b74270f21c60863622272012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negative-QTOFsplash10-002b-9000000000-bc69e8fa215a3b82dcf22012-08-31HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ , negative-QTOFsplash10-0a4i-0090000000-d6e539d78b38c01dafea2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Glucose 6-phosphate LC-ESI-QQ , negative-QTOFsplash10-0002-9210000000-10019f92fd1eca143bab2017-09-14HMDB team, MONAView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Glucose 6-phosphate 10V, Positive-QTOFsplash10-03di-0490000000-94ea79ec673f4688b7a02016-09-12Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Glucose 6-phosphate 20V, Positive-QTOFsplash10-03dm-5940000000-c649262446626dcb8d6e2016-09-12Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Glucose 6-phosphate 40V, Positive-QTOFsplash10-0uka-9800000000-aae2cb792906d2dec6cd2016-09-12Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Glucose 6-phosphate 10V, Negative-QTOFsplash10-0a6r-8290000000-8e20219f94b3fe964e382016-09-12Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Glucose 6-phosphate 20V, Negative-QTOFsplash10-004i-9000000000-b19b64f5cb4124047baf2016-09-12Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Glucose 6-phosphate 40V, Negative-QTOFsplash10-004i-9000000000-ecb75a44e3d25affdf312016-09-12Wishart LabView Spectrum

NMR Spectra

Spectrum TypeDescriptionDeposition DateSourceView
Experimental 1D NMR1H NMR Spectrum (1D, 600 MHz, H2O, experimental)2012-12-04Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 100 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 100 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 1000 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 1000 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 200 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 200 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 300 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 300 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 400 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 400 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 500 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 500 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 600 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 600 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 700 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 700 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 800 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 800 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR1H NMR Spectrum (1D, 900 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Predicted 1D NMR13C NMR Spectrum (1D, 900 MHz, D2O, predicted)2021-09-25Wishart LabView Spectrum
Experimental 2D NMR[1H, 13C]-HSQC NMR Spectrum (2D, 600 MHz, H2O, experimental)2012-12-05Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Endoplasmic reticulum
Biospecimen Locations
  • Blood
  • Cellular Cytoplasm
  • Feces
  • Saliva
  • Urine
Tissue Locations
  • Adipose Tissue
  • Adrenal Gland
  • Fibroblasts
  • Kidney
  • Liver
  • Placenta
  • Skeletal Muscle
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothNormal details
BloodDetected and Quantified4.52 +/- 8.7 uMNewborn (0-30 days old)BothNormal
    • Geigy Scientific ...
details
BloodDetected and Quantified29.1 +/- 6.8 uMAdult (>18 years old)BothNormal
    • Geigy Scientific ...
details
Cellular CytoplasmDetected and Quantified38.0 (26.0-50.0) uMAdult (>18 years old)BothNormal details
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal
details
SalivaDetected and Quantified6.88 +/- 3.72 uMAdult (>18 years old)FemaleNormal details
SalivaDetected and Quantified1.60 +/- 1.19 uMAdult (>18 years old)Both
Normal
    • Sugimoto et al. (...
details
SalivaDetected and Quantified1.73 +/- 1.28 uMAdult (>18 years old)Not Specified
Normal
    • Sugimoto et al. (...
details
SalivaDetected and Quantified2.23 +/- 5.59 uMAdult (>18 years old)Not Specified
Normal
    • Sugimoto et al. (...
details
SalivaDetected and Quantified2.42 +/- 1.55 uMAdult (>18 years old)Both
Normal
    • Sugimoto et al. (...
details
UrineDetected but not QuantifiedNot QuantifiedAdult (>18 years old)BothNormal details
Abnormal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Colorectal cancer
details
SalivaDetected and Quantified4.06 +/- 0.96 uMAdult (>18 years old)MaleAlzheimer's disease details
SalivaDetected and Quantified5.51 +/- 3.94 uMAdult (>18 years old)MaleFrontotemporal lobe dementia details
SalivaDetected and Quantified7.79 +/- 8.06 uMAdult (>18 years old)BothLewy body disease details
UrineDetected and Quantified44.163 umol/mmol creatinineChildren (1 - 13 years old)Not Specified
Eosinophilic esophagitis
    • Analysis of 30 no...
details
Associated Disorders and Diseases
Disease References
Colorectal cancer
  1. Goedert JJ, Sampson JN, Moore SC, Xiao Q, Xiong X, Hayes RB, Ahn J, Shi J, Sinha R: Fecal metabolomics: assay performance and association with colorectal cancer. Carcinogenesis. 2014 Sep;35(9):2089-96. doi: 10.1093/carcin/bgu131. Epub 2014 Jul 18. [PubMed:25037050 ]
Alzheimer's disease
  1. Tsuruoka M, Hara J, Hirayama A, Sugimoto M, Soga T, Shankle WR, Tomita M: Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurodegenerative dementia patients. Electrophoresis. 2013 Oct;34(19):2865-72. doi: 10.1002/elps.201300019. Epub 2013 Sep 6. [PubMed:23857558 ]
Frontotemporal dementia
  1. Tsuruoka M, Hara J, Hirayama A, Sugimoto M, Soga T, Shankle WR, Tomita M: Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurodegenerative dementia patients. Electrophoresis. 2013 Oct;34(19):2865-72. doi: 10.1002/elps.201300019. Epub 2013 Sep 6. [PubMed:23857558 ]
Lewy body disease
  1. Tsuruoka M, Hara J, Hirayama A, Sugimoto M, Soga T, Shankle WR, Tomita M: Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurodegenerative dementia patients. Electrophoresis. 2013 Oct;34(19):2865-72. doi: 10.1002/elps.201300019. Epub 2013 Sep 6. [PubMed:23857558 ]
Eosinophilic esophagitis
  1. Slae, M., Huynh, H., Wishart, D.S. (2014). Analysis of 30 normal pediatric urine samples via NMR spectroscopy (unpublished work). NA.
Associated OMIM IDs
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB021818
KNApSAcK IDC00007306
Chemspider ID5743
KEGG Compound IDC00092
BioCyc IDD-glucose-6-phosphate
BiGG ID36977
Wikipedia LinkGlucose_6-phosphate
METLIN ID145
PubChem Compound5958
PDB IDNot Available
ChEBI ID4170
Food Biomarker OntologyNot Available
VMH IDG6P
MarkerDB IDMDB00029998
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Nakayama Y, Kinoshita A, Tomita M: Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition. Theor Biol Med Model. 2005 May 9;2:18. [PubMed:15882454 ]
  2. Price TB, Laurent D, Petersen KF: 13C/31P NMR studies on the role of glucose transport/phosphorylation in human glycogen supercompensation. Int J Sports Med. 2003 May;24(4):238-44. [PubMed:12784164 ]
  3. Boden G, Jadali F, White J, Liang Y, Mozzoli M, Chen X, Coleman E, Smith C: Effects of fat on insulin-stimulated carbohydrate metabolism in normal men. J Clin Invest. 1991 Sep;88(3):960-6. [PubMed:1885781 ]
  4. Lehto M, Xiang K, Stoffel M, Espinosa R 3rd, Groop LC, Le Beau MM, Bell GI: Human hexokinase II: localization of the polymorphic gene to chromosome 2. Diabetologia. 1993 Dec;36(12):1299-302. [PubMed:8307259 ]
  5. Brehm A, Krssak M, Schmid AI, Nowotny P, Waldhausl W, Roden M: Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle. Diabetes. 2006 Jan;55(1):136-40. [PubMed:16380486 ]
  6. Roden M: How free fatty acids inhibit glucose utilization in human skeletal muscle. News Physiol Sci. 2004 Jun;19:92-6. [PubMed:15143200 ]
  7. Chang PY, Jensen J, Printz RL, Granner DK, Ivy JL, Moller DE: Overexpression of hexokinase II in transgenic mice. Evidence that increased phosphorylation augments muscle glucose uptake. J Biol Chem. 1996 Jun 21;271(25):14834-9. [PubMed:8662926 ]
  8. Schalin-Jantti C, Harkonen M, Groop LC: Impaired activation of glycogen synthase in people at increased risk for developing NIDDM. Diabetes. 1992 May;41(5):598-604. [PubMed:1568529 ]
  9. Vaag A, Damsbo P, Hother-Nielsen O, Beck-Nielsen H: Hyperglycaemia compensates for the defects in insulin-mediated glucose metabolism and in the activation of glycogen synthase in the skeletal muscle of patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia. 1992 Jan;35(1):80-8. [PubMed:1541385 ]
  10. Fortpied J, Maliekal P, Vertommen D, Van Schaftingen E: Magnesium-dependent phosphatase-1 is a protein-fructosamine-6-phosphatase potentially involved in glycation repair. J Biol Chem. 2006 Jul 7;281(27):18378-85. Epub 2006 May 1. [PubMed:16670083 ]
  11. Cline GW, Petersen KF, Krssak M, Shen J, Hundal RS, Trajanoski Z, Inzucchi S, Dresner A, Rothman DL, Shulman GI: Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes. N Engl J Med. 1999 Jul 22;341(4):240-6. [PubMed:10413736 ]
  12. Foster JD, Pederson BA, Nordlie RC: Glucose-6-phosphatase structure, regulation, and function: an update. Proc Soc Exp Biol Med. 1997 Sep;215(4):314-32. [PubMed:9270716 ]
  13. Turvey EA, Heigenhauser GJ, Parolin M, Peters SJ: Elevated n-3 fatty acids in a high-fat diet attenuate the increase in PDH kinase activity but not PDH activity in human skeletal muscle. J Appl Physiol (1985). 2005 Jan;98(1):350-5. [PubMed:15591305 ]
  14. Benkoel L, Chamlian A, Barrat E, Laffargue P: The use of ferricyanide for the electron microscopic demonstration of dehydrogenases in human steroidogenic cells. J Histochem Cytochem. 1976 Nov;24(11):1194-203. [PubMed:1002973 ]
  15. Villar-Palasi C, Guinovart JJ: The role of glucose 6-phosphate in the control of glycogen synthase. FASEB J. 1997 Jun;11(7):544-58. [PubMed:9212078 ]
  16. Vestergaard H, Bjorbaek C, Hansen T, Larsen FS, Granner DK, Pedersen O: Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients. J Clin Invest. 1995 Dec;96(6):2639-45. [PubMed:8675629 ]
  17. Roussel R, Carlier PG, Wary C, Velho G, Bloch G: Evidence for 100% 13C NMR visibility of glucose in human skeletal muscle. Magn Reson Med. 1997 Jun;37(6):821-4. [PubMed:9178231 ]
  18. Cigolini M, Bonora E, Querena M, Moghetti P, Cacciatori V, Zancanaro C, Benati D, Muggeo M: Differences in glucose metabolic enzyme activities in human adipose tissue from abdominal and gluteal regions. Metabolism. 1988 Sep;37(9):820-3. [PubMed:3419322 ]
  19. Petersen KF, Hendler R, Price T, Perseghin G, Rothman DL, Held N, Amatruda JM, Shulman GI: 13C/31P NMR studies on the mechanism of insulin resistance in obesity. Diabetes. 1998 Mar;47(3):381-6. [PubMed:9519743 ]
  20. Boden G, Chen X, Ruiz J, White JV, Rossetti L: Mechanisms of fatty acid-induced inhibition of glucose uptake. J Clin Invest. 1994 Jun;93(6):2438-46. [PubMed:8200979 ]
  21. Elshenawy S, Pinney SE, Stuart T, Doulias PT, Zura G, Parry S, Elovitz MA, Bennett MJ, Bansal A, Strauss JF 3rd, Ischiropoulos H, Simmons RA: The Metabolomic Signature of the Placenta in Spontaneous Preterm Birth. Int J Mol Sci. 2020 Feb 4;21(3). pii: ijms21031043. doi: 10.3390/ijms21031043. [PubMed:32033212 ]

Only showing the first 10 proteins. There are 20 proteins in total.

Enzymes

General function:
Involved in ATP binding
Specific function:
Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
Gene Name:
GCK
Uniprot ID:
P35557
Molecular weight:
52191.07
Reactions
Adenosine triphosphate + D-Glucose → ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + alpha-D-Glucose → ADP + Glucose 6-phosphatedetails
General function:
Involved in ATP binding
Specific function:
Not Available
Gene Name:
HK3
Uniprot ID:
P52790
Molecular weight:
99024.56
Reactions
Adenosine triphosphate + D-Galactose → ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + D-Glucose → ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + alpha-D-Glucose → ADP + Glucose 6-phosphatedetails
General function:
Involved in ATP binding
Specific function:
Not Available
Gene Name:
HK2
Uniprot ID:
P52789
Molecular weight:
102379.06
Reactions
Adenosine triphosphate + D-Galactose → ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + D-Glucose → ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + alpha-D-Glucose → ADP + Glucose 6-phosphatedetails
General function:
Involved in ATP binding
Specific function:
Not Available
Gene Name:
HK1
Uniprot ID:
P19367
Molecular weight:
102485.1
Reactions
Adenosine triphosphate + D-Galactose → ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + D-Glucose → ADP + Glucose 6-phosphatedetails
Adenosine triphosphate + alpha-D-Glucose → ADP + Glucose 6-phosphatedetails
General function:
Involved in glucose-6-phosphate dehydrogenase activity
Specific function:
Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power.
Gene Name:
G6PD
Uniprot ID:
P11413
Molecular weight:
62467.88
Reactions
Glucose 6-phosphate + NADP → 6-phospho-D-glucono-1,5-lactone + NADPHdetails
General function:
Involved in 6-phosphogluconolactonase activity
Specific function:
Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates.
Gene Name:
H6PD
Uniprot ID:
O95479
Molecular weight:
88891.99
Reactions
Glucose 6-phosphate + NAD(P)(+) → 6-Phosphonoglucono-D-lactone + NAD(P)Hdetails
General function:
Involved in phosphotransferase activity, alcohol group as acceptor
Specific function:
Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity).
Gene Name:
ADPGK
Uniprot ID:
Q9BRR6
Molecular weight:
53960.185
Reactions
ADP + D-Glucose → Adenosine monophosphate + Glucose 6-phosphatedetails
alpha-D-Glucose + ADP → Glucose 6-phosphate + Adenosine monophosphatedetails
General function:
Involved in phosphorylase activity
Specific function:
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Gene Name:
PYGL
Uniprot ID:
P06737
Molecular weight:
93133.25
General function:
Involved in phosphorylase activity
Specific function:
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Gene Name:
PYGM
Uniprot ID:
P11217
Molecular weight:
87316.355
General function:
Involved in phosphorylase activity
Specific function:
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Gene Name:
PYGB
Uniprot ID:
P11216
Molecular weight:
96695.18

Only showing the first 10 proteins. There are 20 proteins in total.