Hmdb loader
Record Information
Version5.0
StatusExpected but not Quantified
Creation Date2012-09-06 15:16:52 UTC
Update Date2022-03-07 02:52:00 UTC
HMDB IDHMDB0015511
Secondary Accession Numbers
  • HMDB15511
Metabolite Identification
Common NameBromazepam
DescriptionBromazepam is only found in individuals that have used or taken this drug. It is one of the benzodiazepines that is used in the treatment of anxiety disorders. [PubChem] It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances.Bromazepam binds to the GABA receptor GABAA, causing a conformational change and increasing inhibitory effects of GABA. Other neurotransmitters are not influenced.
Structure
Data?1582753305
Synonyms
ValueSource
LectopamKegg
7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiaxepin-2(1H)-oneHMDB
7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiazepin-2(1H)-oneHMDB
1a Brand OF bromazepamHMDB
Bromazepam lichtenstein brandHMDB
Bromazepam betaHMDB
Heumann brand OF bromazepamHMDB
LexatinHMDB
Betapharm brand OF bromazepamHMDB
Apo-bromazepamHMDB
Apotex brand OF bromazepamHMDB
Bromaz 1a pharmaHMDB
Hexal brand OF bromazepamHMDB
CT-Arzneimittel brand OF bromazepamHMDB
DurazanilHMDB
Aliud brand OF bromazepamHMDB
Apo bromazepamHMDB
Bromazepam heumannHMDB
Bromazepam ratiopharmHMDB
Bromazepam-neuraxpharmHMDB
Bromazepam-ratiopharmHMDB
Gen-bromazepamHMDB
LexomilHMDB
LexotanHMDB
Roche brand OF bromazepamHMDB
Neuraxpharm brand OF bromazepamHMDB
Ratiopharm brand OF bromazepamHMDB
AnxyrexHMDB
BromaLichHMDB
BromazanilHMDB
Bromazepam alHMDB
Bromazepam roche brandHMDB
Gen bromazepamHMDB
Genpharm brand OF bromazepamHMDB
Irex brand OF bromazepamHMDB
LexotanilHMDB
Lichtenstein brand OF bromazepamHMDB
Merck dura brand OF bromazepamHMDB
Bromazep von CTHMDB
CT Arzneimittel brand OF bromazepamHMDB
Beta, BromazepamHMDB
Bromazepam neuraxpharmHMDB
Von CT, bromazepHMDB
Chemical FormulaC14H10BrN3O
Average Molecular Weight316.153
Monoisotopic Molecular Weight315.000724604
IUPAC Name7-bromo-5-(pyridin-2-yl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Traditional Namebromazepam
CAS Registry Number1812-30-2
SMILES
BrC1=CC2=C(NC(=O)CN=C2C2=CC=CC=N2)C=C1
InChI Identifier
InChI=1S/C14H10BrN3O/c15-9-4-5-11-10(7-9)14(17-8-13(19)18-11)12-3-1-2-6-16-12/h1-7H,8H2,(H,18,19)
InChI KeyVMIYHDSEFNYJSL-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as 1,4-benzodiazepines. These are organic compounds containing a benzene ring fused to a 1,4-azepine.
KingdomOrganic compounds
Super ClassOrganoheterocyclic compounds
ClassBenzodiazepines
Sub Class1,4-benzodiazepines
Direct Parent1,4-benzodiazepines
Alternative Parents
Substituents
  • 1,4-benzodiazepine
  • Alpha-amino acid or derivatives
  • Aryl bromide
  • Aryl halide
  • Pyridine
  • Benzenoid
  • Heteroaromatic compound
  • Carboxamide group
  • Ketimine
  • Lactam
  • Secondary carboxylic acid amide
  • Carboxylic acid derivative
  • Azacycle
  • Organic 1,3-dipolar compound
  • Propargyl-type 1,3-dipolar organic compound
  • Organobromide
  • Organohalogen compound
  • Hydrocarbon derivative
  • Imine
  • Organic nitrogen compound
  • Organic oxide
  • Carbonyl group
  • Organonitrogen compound
  • Organooxygen compound
  • Organic oxygen compound
  • Organopnictogen compound
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External DescriptorsNot Available
Ontology
Not AvailableNot Available
Physical Properties
StateSolid
Experimental Molecular Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water Solubility0.04 g/LNot Available
LogP2.05SANGSTER (1994)
Experimental Chromatographic Properties

Experimental Collision Cross Sections

Adduct TypeData SourceCCS Value (Å2)Reference
[M+H]+CBM159.830932474
Predicted Molecular Properties
PropertyValueSource
Water Solubility0.04 g/LALOGPS
logP2.09ALOGPS
logP2.54ChemAxon
logS-3.9ALOGPS
pKa (Strongest Acidic)12.24ChemAxon
pKa (Strongest Basic)2.68ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area54.35 ŲChemAxon
Rotatable Bond Count1ChemAxon
Refractivity76.99 m³·mol⁻¹ChemAxon
Polarizability28.11 ųChemAxon
Number of Rings3ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DeepCCS[M+H]+159.80430932474
DeepCCS[M-H]-157.40930932474
DeepCCS[M-2H]-190.42730932474
DeepCCS[M+Na]+165.81130932474
AllCCS[M+H]+167.532859911
AllCCS[M+H-H2O]+163.732859911
AllCCS[M+NH4]+170.932859911
AllCCS[M+Na]+171.932859911
AllCCS[M-H]-162.932859911
AllCCS[M+Na-2H]-162.632859911
AllCCS[M+HCOO]-162.532859911

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
BromazepamBrC1=CC2=C(NC(=O)CN=C2C2=CC=CC=N2)C=C13397.9Standard polar33892256
BromazepamBrC1=CC2=C(NC(=O)CN=C2C2=CC=CC=N2)C=C12642.5Standard non polar33892256
BromazepamBrC1=CC2=C(NC(=O)CN=C2C2=CC=CC=N2)C=C12649.5Semi standard non polar33892256

Derivatized

Derivative Name / StructureSMILESKovats RI ValueColumn TypeReference
Bromazepam,1TMS,isomer #1C[Si](C)(C)N1C(=O)CN=C(C2=CC=CC=N2)C2=CC(Br)=CC=C212375.1Semi standard non polar33892256
Bromazepam,1TMS,isomer #1C[Si](C)(C)N1C(=O)CN=C(C2=CC=CC=N2)C2=CC(Br)=CC=C212481.4Standard non polar33892256
Bromazepam,1TMS,isomer #1C[Si](C)(C)N1C(=O)CN=C(C2=CC=CC=N2)C2=CC(Br)=CC=C213788.8Standard polar33892256
Bromazepam,1TBDMS,isomer #1CC(C)(C)[Si](C)(C)N1C(=O)CN=C(C2=CC=CC=N2)C2=CC(Br)=CC=C212603.8Semi standard non polar33892256
Bromazepam,1TBDMS,isomer #1CC(C)(C)[Si](C)(C)N1C(=O)CN=C(C2=CC=CC=N2)C2=CC(Br)=CC=C212700.3Standard non polar33892256
Bromazepam,1TBDMS,isomer #1CC(C)(C)[Si](C)(C)N1C(=O)CN=C(C2=CC=CC=N2)C2=CC(Br)=CC=C213875.7Standard polar33892256
Spectra

GC-MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Predicted GC-MSPredicted GC-MS Spectrum - Bromazepam GC-MS (Non-derivatized) - 70eV, Positivesplash10-000i-0091000000-cf3c3fba2d2e801551b12017-09-01Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Bromazepam GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - Bromazepam GC-MS (Non-derivatized) - 70eV, PositiveNot Available2021-10-12Wishart LabView Spectrum
MSMass Spectrum (Electron Ionization)splash10-00n0-9463000000-abe7fdab778f08fe18c42014-09-20Not AvailableView Spectrum

MS/MS Spectra

Spectrum TypeDescriptionSplash KeyDeposition DateSourceView
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , negative-QTOFsplash10-03di-0049000000-67c4bd48b889caf68ca32017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , negative-QTOFsplash10-000i-0090000000-8d6819f4db99e73f4dbe2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , negative-QTOFsplash10-002r-6090000000-f5e0ef1096bea72d5c892017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , negative-QTOFsplash10-004i-9010000000-19864d6c0a50c513bb182017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , negative-QTOFsplash10-004i-9000000000-59557fda51a0ea2c63d72017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , negative-QTOFsplash10-004i-9000000000-6b0acd4d149e1fb20f9a2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , negative-QTOFsplash10-004i-9000000000-6b0acd4d149e1fb20f9a2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , negative-QTOFsplash10-004i-9000000000-6b0acd4d149e1fb20f9a2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , negative-QTOFsplash10-004i-9000000000-6b0acd4d149e1fb20f9a2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QTOF , positive-QTOFsplash10-014i-0379000000-14ceeb34a706f6a12f412017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , positive-QTOFsplash10-014i-0009000000-09662342e908d558048e2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , positive-QTOFsplash10-014i-0029000000-4b93291583996cb3cbda2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , positive-QTOFsplash10-05o0-0492000000-035f589c482b481c51522017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , positive-QTOFsplash10-053r-1890000000-1997ad0374625359f4832017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , positive-QTOFsplash10-053r-1960000000-4f105348e7e7804313ce2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , positive-QTOFsplash10-053r-1930000000-b0f688a41f88a133b74b2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , positive-QTOFsplash10-0f89-1910000000-c0dd1d47a44a292c87b62017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , positive-QTOFsplash10-0fb9-2900000000-706d4c35cde468a8387d2017-09-14HMDB team, MONAView Spectrum
Experimental LC-MS/MSLC-MS/MS Spectrum - Bromazepam LC-ESI-QFT , positive-QTOFsplash10-004i-6900000000-85795e315602b7e61a6b2017-09-14HMDB team, MONAView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Bromazepam 10V, Positive-QTOFsplash10-014i-0019000000-9838285fc2c3cd651ac22016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Bromazepam 20V, Positive-QTOFsplash10-014r-0096000000-280bb1a170e2f078b4e02016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Bromazepam 40V, Positive-QTOFsplash10-000i-2090000000-b45001feb54839adf3072016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Bromazepam 10V, Negative-QTOFsplash10-03di-0009000000-f5383e2ca907102396d12016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Bromazepam 20V, Negative-QTOFsplash10-03di-0029000000-68359119cecb7b2899e12016-08-03Wishart LabView Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - Bromazepam 40V, Negative-QTOFsplash10-001i-2191000000-ee5f9b155d34898671dc2016-08-03Wishart LabView Spectrum
Biological Properties
Cellular Locations
  • Membrane
Biospecimen Locations
  • Blood
  • Urine
Tissue LocationsNot Available
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
BloodExpected but not QuantifiedNot QuantifiedNot AvailableNot AvailableTaking drug identified by DrugBank entry DB01558 details
UrineExpected but not QuantifiedNot QuantifiedNot AvailableNot AvailableTaking drug identified by DrugBank entry DB01558 details
Abnormal Concentrations
Not Available
Predicted Concentrations
BiospecimenValueOriginal ageOriginal sexOriginal conditionComments
Blood0.000 uMAdult (>18 years old)BothNormalPredicted based on drug qualities
Blood0.000 umol/mmol creatinineAdult (>18 years old)BothNormalPredicted based on drug qualities
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDDB01558
Phenol Explorer Compound IDNot Available
FooDB IDNot Available
KNApSAcK IDNot Available
Chemspider ID2347
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkBromazepam
METLIN IDNot Available
PubChem Compound2441
PDB IDNot Available
ChEBI ID116960
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Oelschlager H: [Chemical and pharmacologic aspects of benzodiazepines]. Schweiz Rundsch Med Prax. 1989 Jul 4;78(27-28):766-72. [PubMed:2570451 ]
  2. Ochs HR, Greenblatt DJ, Friedman H, Burstein ES, Locniskar A, Harmatz JS, Shader RI: Bromazepam pharmacokinetics: influence of age, gender, oral contraceptives, cimetidine, and propranolol. Clin Pharmacol Ther. 1987 May;41(5):562-70. [PubMed:2882883 ]
  3. van Harten J: Overview of the pharmacokinetics of fluvoxamine. Clin Pharmacokinet. 1995;29 Suppl 1:1-9. [PubMed:8846617 ]
  4. Oda M, Kotegawa T, Tsutsumi K, Ohtani Y, Kuwatani K, Nakano S: The effect of itraconazole on the pharmacokinetics and pharmacodynamics of bromazepam in healthy volunteers. Eur J Clin Pharmacol. 2003 Nov;59(8-9):615-9. Epub 2003 Sep 27. [PubMed:14517708 ]

Only showing the first 10 proteins. There are 23 proteins in total.

Enzymes

General function:
Involved in monooxygenase activity
Specific function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide.
Gene Name:
CYP3A4
Uniprot ID:
P08684
Molecular weight:
57255.585
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
General function:
Involved in monooxygenase activity
Specific function:
Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
Gene Name:
CYP2C19
Uniprot ID:
P33261
Molecular weight:
55944.565
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
General function:
Involved in monooxygenase activity
Specific function:
Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
Gene Name:
CYP2E1
Uniprot ID:
P05181
Molecular weight:
56848.42
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
General function:
Involved in monooxygenase activity
Specific function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Gene Name:
CYP1A2
Uniprot ID:
P05177
Molecular weight:
58406.915
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
General function:
Involved in ion transport
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRG2
Uniprot ID:
P18507
Molecular weight:
54161.8
References
  1. Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. doi: 10.1111/j.1600-0404.2008.01004.x. Epub 2008 Mar 31. [PubMed:18384456 ]
General function:
Involved in ion transport
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA1
Uniprot ID:
P14867
Molecular weight:
51801.4
References
  1. Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. doi: 10.1111/j.1600-0404.2008.01004.x. Epub 2008 Mar 31. [PubMed:18384456 ]
General function:
Involved in ion transport
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA2
Uniprot ID:
P47869
Molecular weight:
51325.9
References
  1. Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. doi: 10.1111/j.1600-0404.2008.01004.x. Epub 2008 Mar 31. [PubMed:18384456 ]
General function:
Involved in ion transport
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA3
Uniprot ID:
P34903
Molecular weight:
55164.1
References
  1. Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. doi: 10.1111/j.1600-0404.2008.01004.x. Epub 2008 Mar 31. [PubMed:18384456 ]
General function:
Involved in ion transport
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA4
Uniprot ID:
P48169
Molecular weight:
61622.6
References
  1. Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. doi: 10.1111/j.1600-0404.2008.01004.x. Epub 2008 Mar 31. [PubMed:18384456 ]
General function:
Involved in ion transport
Specific function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel
Gene Name:
GABRA5
Uniprot ID:
P31644
Molecular weight:
52145.6
References
  1. Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand. 2008 Aug;118(2):69-86. doi: 10.1111/j.1600-0404.2008.01004.x. Epub 2008 Mar 31. [PubMed:18384456 ]

Only showing the first 10 proteins. There are 23 proteins in total.