Hmdb loader

HMDBP00272 (Catechol O-methyltransferase) Metabolite Associations

Displaying metabolite protein links 76 - 94 of 94 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0030802Patuletin519-96-0ThumbC16H12O8332.2617
332.05321736		Not Available
HMDB00308042-(3,4-Dihydroxyphenyl)-5,6-dihydroxy-7-methoxy-4H-1-benzopyran-4-one22384-63-0ThumbC16H12O7316.2623
316.058302738		Not Available
HMDB0001185S-Adenosylmethionine485-80-3ThumbC15H23N6O5S399.445
399.145063566		Not Available
HMDB00305413,3',4',7-TetrahydroxyflavanThumbC15H14O5274.2687
274.084123558		Not Available
HMDB00416513',4',5,7-TetrahydroxyisoflavanoneThumbC15H12O6288.2522
288.063388116		Not Available
HMDB0002708Cyanidin13306-05-3ThumbC15H11O6287.2442
287.055563084		Not Available
HMDB0005794Quercetin117-39-5ThumbC15H10O7302.2357
302.042652674		Not Available
HMDB0005800Luteolin491-70-3ThumbC15H10O6286.2363
286.047738052		Not Available
HMDB00416583'-HydroxygenisteinThumbC15H10O6286.2363
286.047738052		Not Available
HMDB0000939S-Adenosylhomocysteine979-92-0ThumbC14H20N6O5S384.411
384.12158847		Not Available
HMDB0012226Entacapone130929-57-6ThumbC14H15N3O5305.286
305.101170605		Not Available
HMDB00042153,3',4'5-Tetrahydroxystilbene10083-24-6ThumbC14H12O4244.246
244.073558866		Not Available
HMDB0014468Tolcapone134308-13-7ThumbC14H11NO5273.2408
273.063722467
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Ries V, Selzer R, Eichhorn T, Oertel WH, Eggert K: Replacing a dopamine agonist by the COMT-inhibitor tolcapone as an adjunct to L-dopa in the treatment of Parkinson's disease: a randomized, multicenter, open-label, parallel-group study. Clin Neuropharmacol. 2010 May;33(3):142-50. doi: 10.1097/WNF.0b013e3181d99d6f. [PubMed:20502133 ]
  3. Guay DR: Tolcapone, a selective catechol-O-methyltransferase inhibitor for treatment of Parkinson's disease. Pharmacotherapy. 1999 Jan;19(1):6-20. [PubMed:9917075 ]
  4. Keating GM, Lyseng-Williamson KA: Tolcapone: a review of its use in the management of Parkinson's disease. CNS Drugs. 2005;19(2):165-84. [PubMed:15697329 ]
  5. Truong DD: Tolcapone: review of its pharmacology and use as adjunctive therapy in patients with Parkinson's disease. Clin Interv Aging. 2009;4:109-13. Epub 2009 May 14. [PubMed:19503773 ]
  6. Apud JA, Mattay V, Chen J, Kolachana BS, Callicott JH, Rasetti R, Alce G, Iudicello JE, Akbar N, Egan MF, Goldberg TE, Weinberger DR: Tolcapone improves cognition and cortical information processing in normal human subjects. Neuropsychopharmacology. 2007 May;32(5):1011-20. Epub 2006 Oct 25. [PubMed:17063156 ]
  7. Stocchi F, De Pandis MF: Utility of tolcapone in fluctuating Parkinson's disease. Clin Interv Aging. 2006;1(4):317-25. [PubMed:18046910 ]
  8. Forsberg M, Lehtonen M, Heikkinen M, Savolainen J, Jarvinen T, Mannisto PT: Pharmacokinetics and pharmacodynamics of entacapone and tolcapone after acute and repeated administration: a comparative study in the rat. J Pharmacol Exp Ther. 2003 Feb;304(2):498-506. [PubMed:12538800 ]
  9. Tai CH, Wu RM: Catechol-O-methyltransferase and Parkinson's disease. Acta Med Okayama. 2002 Feb;56(1):1-6. [PubMed:11873938 ]
  10. Kaakkola S: Clinical pharmacology, therapeutic use and potential of COMT inhibitors in Parkinson's disease. Drugs. 2000 Jun;59(6):1233-50. [PubMed:10882160 ]
  11. Ruottinen HM, Rinne UK: COMT inhibition in the treatment of Parkinson's disease. J Neurol. 1998 Nov;245(11 Suppl 3):P25-34. [PubMed:9808337 ]
HMDB00416794-Hydroxy-(3',4'-dihydroxyphenyl)-valeric acidThumbC11H14O5226.2259
226.084123558		Not Available
HMDB00292333,4-Dihydroxyphenylvaleric acidThumbC11H14O4210.2265
210.089208936		Not Available
HMDB00291855-(3',4'-Dihydroxyphenyl)-gamma-valerolactone191666-22-5ThumbC11H12O4208.213
208.073558866		Not Available
HMDB0004063Metanephrine5001-33-2ThumbC10H15NO3197.231
197.105193351		Not Available
HMDB0011754Methyldopa555-30-6ThumbC10H13NO4211.2145
211.084457909		Not Available
HMDB00416613,4-Dihydroxyphenyllactic acid methyl esterThumbC10H12O5212.1993
212.068473494		Not Available
Displaying metabolite protein links 76 - 94 of 94 in total