Human Metabolome Database: Showing Protein Copine-7 (HMDBP07625)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 metabolite

Identification
HMDB Protein ID	HMDBP07625
Secondary Accession Numbers	13334
Name	Copine-7
Synonyms	Copine VII
Gene Name	CPNE7
Protein Type	Unknown
Biological Properties
General Function	Involved in transporter activity
Specific Function	May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties
Pathways	Not Available
Reactions	Not Available
GO Classification	Not Available
Cellular Location	Not Available
Gene Properties
Chromosome Location	Chromosome:1
Locus	16q24.3
SNPs	CPNE7
Gene Sequence	>1902 bp ATGAGCGCGGGCTCGGAGCGCGGGGCGGCGGCAACCCCCGGGGGTTTGCCCGCGCCCTGC GCCTCGAAGGTGGAGCTGCGGCTCAGCTGCCGGCACCTGCTGGACCGCGACCCGCTCACC AAGTCCGACCCCAGCGTGGCGTTGCTGCAGCAGGCGCAGGGCCAGTGGGTGCAGGTGGGC AGAACCGAGGTGGTCCGGAGCAGCCTGCATCCCGTGTTCTCCAAGGTCTTCACGGTGGAC TACTACTTCGAGGAGGTGCAGAGGCTGCGCTTTGAGGTGTACGACACGCATGGGCCCAGC GGCTTCAGCTGTCAGGAGGACGATTTCCTGGGGGGCATGGAGTGCACCCTGGGGCAGCCA GCCCAAAAGTGGCTTCTGCAAGTCGTGATGAGAGTGTCTGTTGATGTGCTGGGCCCTGCT GGACACTGCGCTAAGCACTTCCTGTGCTGCACGGAATCCTCACACCTTGCCAGGACGGGT CCTTCTTTTTTATTGAGGTATGATGACCTCTGCCTCCCCTGGGCGACTGCTGGCGCCGTG AGGTGGTGGACGTGCAGGGGTGGCCACACGCAGGGATGGCAGATTGTGGCCCAGAAGAAG GTGACCCGCCCGCTGCTGCTCAAGTTTGGCAGGAACGCTGGCAAGTCCACCATCACGGTG ATCGCCGAGGACATCTCGGGGAACAACGGCTACGTGGAGCTCTCCTTCCGGGCCAGGAAG CTGGACGACAAGGACCTCTTCAGCAAGTCCGACCCCTTCCTGGAGCTCTACAGGGTCAAC GACGACCAGGGCTTGCAGCTGGTGTACAGGACGGAGGTGGTGAAGAACAACCTGAACCCG GTGTGGGAGGCCTTCAAAGTCTCTCTGAGTTCCCTCTGCAGCTGCGAGGAGACAAGGCCT CTAAAGTGCCTGGTCTGGGATTACGACTCTCGAGGAAAGCACGACTTCATCGGAGAATTC TCTACCACCTTCGAGGAGATGCAGAAGGCCTTTGAGGAGGGGCAGGCCCAGTGGGACTGT GTGAACCCCAAATACAAGCAGAAGAGACGCAGTTATAAGAACTCAGGAGTGGTCGTCCTG GCTGACCTCAAGTTCCACAGGGTGTACTCCTTCCTGGACTATATCATGGGCGGCTGCCAG ATCCACTTCACCGTGGCCATTGACTTCACCGCCTCCAATGGAGACCCGCGGAACAGCTGC TCCCTGCACTACATCAACCCCTACCAGCCGAACGAGTACCTGAAGGCACTGGTGTCCGTG GGCGAGATCTGCCAGGACTATGACAGTGACAAGAGGTTTTCCGCTTTGGGGTTTGGAGCC CGGATCCCTCCCAAGTATGAGGTGTCCCATGACTTTGCCATCAATTTCAACCCTGAGGAC GATGAGTGTGAAGGCATCCAGGGCGTGGTGGAGGCCTACCAGAACTGCCTGCCCAGGGTC CAGCTCTACGGCCCCACCAACGTGGCGCCCATCATCTCCAAGGTGGCACGCGTGGCGGCG GCCGAGGAGAGCACCGGGAAAGCCTCTCAATACTACATCCTGCTGATCCTGACGGACGGC GTGGTGACCGACATGGCCGACACACGGGAGGCCATTGTGCGTGCCTCACGCCTGCCCATG TCCATCATCATCGTGGGCGTGGGCAACGCCGACTTCACCGACATGCAGGTCCTGGACGGC GACGACGGCGTCCTGCGCTCCCCACGGGGTGAGCCCGCGCTCCGGGACATCGTACAGTTC GTGCCCTTCCGGGAGCTCAAGAACGCATCCCCTGCGGCGCTGGCCAAGTGCGTGCTGGCC GAGGTCCCGAAGCAGGTGGTGGAGTACTACAGCCACAGAGGCCTGCCCCCGAGAAGCCTG GGTGTCCCTGCCGGAGAGGCCAGCCCAGGCTGCACACCGTGA
Protein Properties
Number of Residues	633
Molecular Weight	70293.3
Theoretical pI	6.33
Pfam Domain Function	C2 (PF00168 ) Copine (PF07002 )
Signals	None
Transmembrane Regions	None
Protein Sequence	>Copine-7 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQP AQKWLLQVVMRVSVDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAV RWWTCRGGHTQGWQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARK LDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRP LKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVL ADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSV GEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRV QLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPM SIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLA EVPKQVVEYYSHRGLPPRSLGVPAGEASPGCTP
External Links
GenBank ID Protein	6453352
UniProtKB/Swiss-Prot ID	Q9UBL6
UniProtKB/Swiss-Prot Entry Name	CPNE7_HUMAN
PDB IDs	Not Available
GenBank Gene ID	AJ133798
GeneCard ID	CPNE7
GenAtlas ID	CPNE7
HGNC ID	HGNC:2320
References
General References	Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ] Savino M, d'Apolito M, Centra M, van Beerendonk HM, Cleton-Jansen AM, Whitmore SA, Crawford J, Callen DF, Zelante L, Savoia A: Characterization of copine VII, a new member of the copine family, and its exclusion as a candidate in sporadic breast cancers with loss of heterozygosity at 16q24.3. Genomics. 1999 Oct 15;61(2):219-26. [PubMed:10534407 ]