following absorption, ifosfamide is converted into 4-hydroxyifosfamide by a variety of cytochrome p450 isozymes in the liver. 4-hydroxyifosfamide crosses the plasma membrane of the cancer cell and spontaneuosly forms aldoifosfamide.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Ifosfamide Action Pathway'