it does so by competing for the same binding site as norepinephrine on the sodium-dependent noradraneline transporter (slc6a2) and by competing with serotonin for binding to the sodium-dependent serotonin transporter (slc6a4). this increases the concentrations of both norepinephrine and serotonin in their respective synapses and reverses the state of low concentrations of both neurotransmitters found in depression.
Parent Term
Biochemical pathway
Parent Definition
A linked series of chemical reactions that occur in a defined order within or between organism cells, and lead to a known function or end product.
Other Metabolites Mapped to 'Imipramine Action Pathway'