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Human Metabolome Database Version 3.5

Showing metabocard for Guanosine diphosphate (HMDB01201)

• Identification
• Taxonomy
• Ontology
• Physical properties
• Spectra
• Biological properties
• Concentrations
• Links
• References

enzymes (214)

• Blood
• Urine

Record Information
Version	3.5
Creation Date	2005-11-16 08:48:42 -0700
Update Date	2013-02-08 17:10:05 -0700
HMDB ID	HMDB01201
Secondary Accession Numbers	None
Metabolite Identification
Common Name	Guanosine diphosphate
Description	Guanosine 5'-(trihydrogen diphosphate). A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. It is an ester of pyrophosphoric acid with the nucleoside guanosine. GDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase guanine. GDP is the product of GTP dephosphorylation by GTPases, e.g. the G-proteins that are involved in signal transduction.
Structure	Download: MOL | SDF | SMILES | InChI Display: 2D Structure | 3D Structure
Synonyms	5'-GDP GDP Guanosine 5'-(trihydrogen pyrophosphate) Guanosine 5'-diphosphate Guanosine 5'-pyrophosphate Guanosine mono(trihydrogen diphosphate) Guanosine pyrophosphate Guanosine-5'-diphosphate Guanosine-diphosphate PpG
Chemical Formula	C10H15N5O11P2
Average Molecular Weight	443.2005
Monoisotopic Molecular Weight	443.024329371
IUPAC Name	[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid
Traditional IUPAC Name	{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy(hydroxy)phosphoryl}oxyphosphonic acid
CAS Registry Number	146-91-8
SMILES	NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1
InChI Identifier	InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChI Key	QGWNDRXFNXRZMB-UUOKFMHZSA-N
Chemical Taxonomy
Kingdom	Organic Compounds
Super Class	Nucleosides, Nucleotides, and Analogues
Class	Purine Nucleotides
Sub Class	Purine Ribonucleotides
Other Descriptors	Aromatic Heteropolycyclic Compounds Ribonucleotides(KEGG) guanosine 5'-phosphate(ChEBI) purine ribonucleoside 5'-diphosphate(ChEBI)
Substituents	1,2 Diol 1 Phosphoribosyl Imidazole Aminopyrimidine Glycosyl Compound Hypoxanthine Imidazole Imidazopyrimidine Monosaccharide Phosphate N Glycosyl Compound Organic Hypophosphite Organic Phosphite Organic Pyrophosphate Oxolane Pentose Monosaccharide Phosphoric Acid Ester Purine Purinone Pyrimidine Pyrimidone Saccharide Secondary Alcohol
Direct Parent	Purine Ribonucleoside Diphosphates
Ontology
Status	Detected and Quantified
Origin	Endogenous
Biofunction	Component of Fructose and mannose metabolism
Application	Not Available
Cellular locations	Cytoplasm Extracellular Mitochondria Nucleus Golgi apparatus
Physical Properties
State	Solid
Experimental Properties	Property Value Reference Melting Point Not Available Not Available Boiling Point Not Available Not Available Water Solubility Not Available Not Available LogP Not Available Not Available
Predicted Properties	Property Value Source Water Solubility 4.44 g/L ALOGPS LogP -1.51 ALOGPS LogP -3.5 ChemAxon LogS -2.00 ALOGPS pKa (strongest acidic) 1.97 ChemAxon pKa (strongest basic) 1.35 ChemAxon Hydrogen Acceptor Count 12 ChemAxon Hydrogen Donor Count 7 ChemAxon Polar Surface Area 248.28 A2 ChemAxon Rotatable Bond Count 6 ChemAxon Refractivity 86.37 ChemAxon Polarizability 35.28 ChemAxon Formal Charge 0 ChemAxon Physiological Charge -2 ChemAxon
Spectra
	1H NMR Spectrum MS/MS Spectrum Quattro_QQQ 10 MS/MS Spectrum Quattro_QQQ 25 MS/MS Spectrum Quattro_QQQ 40 [1H,1H] 2D NMR Spectrum [1H,13C] 2D NMR Spectrum
Biological Properties
Cellular Locations	Cytoplasm Extracellular Mitochondria Nucleus Golgi apparatus
Biofluid Locations	Blood Cerebrospinal Fluid (CSF)
Tissue Location	Not Available
Pathways	Name SMPDB Link KEGG Link Citric Acid Cycle SMP00057 map00020 Gluconeogenesis SMP00128 map00010 Purine Metabolism SMP00050 map00230
Normal Concentrations
	Biofluid Status Value Age Sex Condition Comments Blood Detected and Quantified 15.0 +/- 2.0 uM Adult (>18 years old) Male Normal Not Available Blood Detected and Quantified 18.0 +/- 8.0 uM Adult (>18 years old) Both Normal Not Available Cerebrospinal Fluid (CSF) Detected and Quantified 1.86 +/- 0.027 uM Adult (>18 years old) Both Normal Not Available
Abnormal Concentrations
	Biofluid Status Value Age Sex Condition Comments Cerebrospinal Fluid (CSF) Detected and Quantified 2.11 +/- 1.93 uM Adult (>18 years old) Both Rachialgia Not Available Cerebrospinal Fluid (CSF) Detected and Quantified 4.05 +/- 0.03 uM Adult (>18 years old) Both Subarachnoid hemorrhage Not Available Cerebrospinal Fluid (CSF) Detected and Quantified 0.99 +/- 1.32 uM Adult (>18 years old) Both Epilepsy Not Available Cerebrospinal Fluid (CSF) Detected and Quantified 2.55 +/- 1.62 uM Adult (>18 years old) Both Stroke Cerebral stroke Cerebrospinal Fluid (CSF) Detected and Quantified 2.59 +/- 1.77 uM Adult (>18 years old) Both Neuroinfection Not Available
Associated Disorders and Diseases
Disease References	Rachialgia Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662 Subarachnoid hemorrhage Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662 Epilepsy Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662 Stroke Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662 Neuroinfection Czarnecka J, Cieslak M, Michal K: Application of solid phase extraction and high-performance liquid chromatography to qualitative and quantitative analysis of nucleotides and nucleosides in human cerebrospinal fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):85-90. Pubmed: 15993662
Associated OMIM IDs	105800 (Subarachnoid hemorrhage) 540000 (Stroke)
External Links
DrugBank ID	Not Available
Phenol Explorer Compound ID	Not Available
Phenol Explorer Metabolite ID	Not Available
FoodDB ID	FDB022487
KNApSAcK ID	Not Available
Chemspider ID	8630
KEGG Compound ID	C00035
BioCyc ID	GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE
BiGG ID	33599
Wikipedia Link	GDP
NuGOwiki Link	HMDB01201
Metagene Link	HMDB01201
METLIN ID	6077
PubChem Compound	8977
PDB ID	GDP
ChEBI ID	17552
References
Synthesis Reference	Edlin, Gordon; Donini, P. Synthesis of guanosine 5'-diphosphate, 2'-(or 3'-) diphosphate, and related nucleotides in a variety of physiological conditions. Journal of Biological Chemistry (1971), 246(13), 4371-3.
Material Safety Data Sheet (MSDS)	Not Available
General References	Chantin C, Bonin B, Boulieu R, Bory C: Liquid-chromatographic study of purine metabolism abnormalities in purine nucleoside phosphorylase deficiency. Clin Chem. 1996 Feb;42(2):326-8. Pubmed: 8595732

---

Enzymes
Name: Ectonucleoside triphosphate diphosphohydrolase 1 Reactions: ATP + 2 H2O = AMP + 2 phosphate [RN:R00085] Gene Name: ENTPD1 Uniprot ID: P49961 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Soluble calcium-activated nucleotidase 1 Reactions: a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329] Gene Name: CANT1 Uniprot ID: Q8WVQ1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 3 Reactions: ATP + 2 H2O = AMP + 2 phosphate [RN:R00085] Gene Name: ENTPD3 Uniprot ID: O75355 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Uridine-cytidine kinase 1 Reactions: ATP + uridine = ADP + UMP [RN:R00964] Gene Name: UCK1 Uniprot ID: Q9HA47 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate kinase, mitochondrial Reactions: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331] Gene Name: NME4 Uniprot ID: O00746 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ribonucleoside-diphosphate reductase large subunit Reactions: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin [RN:R04294] Gene Name: RRM1 Uniprot ID: P23921 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate kinase A Reactions: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331] Gene Name: NME1 Uniprot ID: P15531 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate kinase 7 Reactions: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331] Gene Name: NME7 Uniprot ID: Q9Y5B8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ribonucleoside-diphosphate reductase subunit M2 Reactions: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin [RN:R04294] Gene Name: RRM2 Uniprot ID: P31350 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate kinase B Reactions: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331] Gene Name: NME2 Uniprot ID: P22392 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate kinase 3 Reactions: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331] Gene Name: NME3 Uniprot ID: Q13232 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate kinase 6 Reactions: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331] Gene Name: NME6 Uniprot ID: O75414 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Fucose-1-phosphate guanylyltransferase Reactions: GTP + beta-L-fucose 1-phosphate = diphosphate + GDP-L-fucose [RN:R01951] Gene Name: FPGT Uniprot ID: O14772 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Alpha-1,3-mannosyltransferase ALG2 Reactions: Gene Name: ALG2 Uniprot ID: Q9H553 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dolichol-phosphate mannosyltransferase Reactions: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate [RN:R01009] Gene Name: DPM1 Uniprot ID: O60762 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GDP-mannose 4,6 dehydratase Reactions: GDP-mannose = GDP-4-dehydro-6-deoxy-D-mannose + H2O [RN:R00888] Gene Name: GMDS Uniprot ID: O60547 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Galactoside 2-alpha-L-fucosyltransferase 2 Reactions: GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D- galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide = GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D- glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11)- ceramide [RN:R04081] Gene Name: FUT2 Uniprot ID: Q10981 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Galactoside 2-alpha-L-fucosyltransferase 1 Reactions: GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D- galactosyl-(1->4)-beta-D-glucosyl-(11)-ceramide = GDP + alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D- glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(11)- ceramide [RN:R04081] Gene Name: FUT1 Uniprot ID: P19526 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 6-phosphofructokinase type C Reactions: ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate [RN:R00756] Gene Name: PFKP Uniprot ID: Q01813 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 6-phosphofructokinase, liver type Reactions: ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate [RN:R00756] Gene Name: PFKL Uniprot ID: P17858 Protein Sequence: FASTA Gene Sequence: FASTA
Name: 6-phosphofructokinase, muscle type Reactions: ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate [RN:R00756] Gene Name: PFKM Uniprot ID: P08237 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pyruvate kinase isozymes M1/M2 Reactions: ATP + pyruvate = ADP + phosphoenolpyruvate [RN:R00200] Gene Name: PKM2 Uniprot ID: P14618 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pyruvate kinase isozymes R/L Reactions: ATP + pyruvate = ADP + phosphoenolpyruvate [RN:R00200] Gene Name: PKLR Uniprot ID: P30613 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 4 Reactions: a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329] Gene Name: ENTPD4 Uniprot ID: Q9Y227 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 6 Reactions: a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329] Gene Name: ENTPD6 Uniprot ID: O75354 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 5 Reactions: a nucleoside diphosphate + H2O = a nucleotide + phosphate [RN:R00329] Gene Name: ENTPD5 Uniprot ID: O75356 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Adenylosuccinate synthetase isozyme 2 Reactions: GTP + IMP + L-aspartate = GDP + phosphate + N6-(1,2-dicarboxyethyl)-AMP [RN:R01135] Gene Name: ADSS Uniprot ID: P30520 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Adenylosuccinate synthetase isozyme 1 Reactions: GTP + IMP + L-aspartate = GDP + phosphate + N6-(1,2-dicarboxyethyl)-AMP [RN:R01135] Gene Name: ADSSL1 Uniprot ID: Q8N142 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial Reactions: GTP + succinate + CoA = GDP + phosphate + succinyl-CoA [RN:R00432] Gene Name: SUCLG1 Uniprot ID: P53597 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial Reactions: GTP + succinate + CoA = GDP + phosphate + succinyl-CoA [RN:R00432] Gene Name: SUCLG2 Uniprot ID: Q96I99 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Reactions: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2 [RN:R00431] Gene Name: PCK1 Uniprot ID: P35558 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GDP-L-fucose synthase Reactions: GDP-L-fucose + NADP+ = GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ [RN:R05692] Gene Name: TSTA3 Uniprot ID: Q13630 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanylate kinase Reactions: ATP + GMP = ADP + GDP [RN:R00332] Gene Name: GUK1 Uniprot ID: Q16774 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial Reactions: ATP + succinate + CoA = ADP + phosphate + succinyl-CoA [RN:R00405] Gene Name: SUCLA2 Uniprot ID: Q9P2R7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Alpha-(1,3)-fucosyltransferase Reactions: GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D- glucosaminyl-R [RN:R04553] Gene Name: FUT5 Uniprot ID: Q11128 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 2 Reactions: Gene Name: RAPGEF2 Uniprot ID: Q9Y4G8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Polyribonucleotide nucleotidyltransferase 1, mitochondrial Reactions: RNAn+1 + phosphate = RNAn + a nucleoside diphosphate [RN:R07282] Gene Name: PNPT1 Uniprot ID: Q8TCS8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 1 Reactions: Gene Name: ARHGEF1 Uniprot ID: Q92888 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Reactions: Gene Name: GNG2 Uniprot ID: P59768 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related C3 botulinum toxin substrate 1 Reactions: Gene Name: RAC1 Uniprot ID: P63000 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho GDP-dissociation inhibitor 3 Reactions: Gene Name: ARHGDIG Uniprot ID: Q99819 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Reactions: Gene Name: GNAS Uniprot ID: P63092 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rab GDP dissociation inhibitor alpha Reactions: Gene Name: GDI1 Uniprot ID: P31150 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Proto-oncogene DBL Reactions: Gene Name: MCF2 Uniprot ID: P10911 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cell division control protein 42 homolog Reactions: Gene Name: CDC42 Uniprot ID: P60953 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rab GDP dissociation inhibitor beta Reactions: Gene Name: GDI2 Uniprot ID: P50395 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho GDP-dissociation inhibitor 1 Reactions: Gene Name: ARHGDIA Uniprot ID: P52565 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho GDP-dissociation inhibitor 2 Reactions: Gene Name: ARHGDIB Uniprot ID: P52566 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related C3 botulinum toxin substrate 2 Reactions: Gene Name: RAC2 Uniprot ID: P15153 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Elongation factor 1-alpha 1 Reactions: Gene Name: EEF1A1 Uniprot ID: P68104 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Elongation factor 1-alpha 2 Reactions: Gene Name: EEF1A2 Uniprot ID: Q05639 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Vinexin Reactions: Gene Name: SORBS3 Uniprot ID: O60504 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTPase HRas Reactions: Gene Name: HRAS Uniprot ID: P01112 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho-related GTP-binding protein RhoQ Reactions: Gene Name: RHOQ Uniprot ID: P17081 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(q) subunit alpha Reactions: Gene Name: GNAQ Uniprot ID: P50148 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-11 Reactions: Gene Name: GNA11 Uniprot ID: P29992 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Reactions: Gene Name: GNG11 Uniprot ID: P61952 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Chitobiosyldiphosphodolichol beta-mannosyltransferase Reactions: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-(1->4)-D-mannosylchitobiosyldiphosphodolichol [RN:R04502 R05972] Gene Name: ALG1 Uniprot ID: Q9BT22 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(t) subunit alpha-1 Reactions: Gene Name: GNAT1 Uniprot ID: P11488 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Uridine-cytidine kinase 2 Reactions: ATP + uridine = ADP + UMP [RN:R00964] Gene Name: UCK2 Uniprot ID: Q9BZX2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein ALEX Reactions: Gene Name: GNAS Uniprot ID: P84996 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 3 Reactions: Gene Name: RAPGEF3 Uniprot ID: O95398 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Lysophosphatidic acid receptor 2 Reactions: Gene Name: LPAR2 Uniprot ID: Q9HBW0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 4 Reactions: Gene Name: RAPGEF4 Uniprot ID: Q8WZA2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Elongation factor 2 Reactions: Gene Name: EEF2 Uniprot ID: P13639 Protein Sequence: FASTA Gene Sequence: FASTA
Name: ENTPD4 protein Reactions: Gene Name: ENTPD4 Uniprot ID: Q8NE73 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Mannose-1-phosphate guanyltransferase beta Reactions: GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose [RN:R00885] Gene Name: GMPPB Uniprot ID: Q9Y5P6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Mannose-1-phosphate guanyltransferase alpha Reactions: GTP + alpha-D-mannose 1-phosphate = diphosphate + GDP-mannose [RN:R00885] Gene Name: GMPPA Uniprot ID: Q96IJ6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Alpha-(1,3)-fucosyltransferase Reactions: Gene Name: FUT9 Uniprot ID: Q9Y231 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Alpha-(1,6)-fucosyltransferase Reactions: GDP-beta-L-fucose + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N- acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D- mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D- glucosaminyl}asparagine = GDP + N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N- acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D- mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L- fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine [RN:R05988] Gene Name: FUT8 Uniprot ID: Q9BYC5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Reactions: Gene Name: PREX1 Uniprot ID: Q8TCU6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ribonucleoside-diphosphate reductase subunit M2 B Reactions: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin [RN:R04294] Gene Name: RRM2B Uniprot ID: Q7LG56 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Uridine-cytidine kinase-like 1 Reactions: ATP + uridine = ADP + UMP [RN:R00964] Gene Name: UCKL1 Uniprot ID: Q9NWZ5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ectonucleoside triphosphate diphosphohydrolase 8 Reactions: ATP + 2 H2O = AMP + 2 phosphate [RN:R00085] Gene Name: ENTPD8 Uniprot ID: Q5MY95 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Synembryn-B Reactions: Gene Name: RIC8B Uniprot ID: Q9NVN3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 6 Reactions: Gene Name: RAPGEF6 Uniprot ID: Q8TEU7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Neuroepithelial cell-transforming gene 1 protein Reactions: Gene Name: NET1 Uniprot ID: Q7Z628 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Cell cycle progression protein 1 Reactions: Gene Name: CCPG1 Uniprot ID: Q9ULG6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Reactions: Gene Name: PREX2 Uniprot ID: Q70Z35 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dynamin-1-like protein Reactions: GTP + H2O = GDP + phosphate [RN:R00335] Gene Name: DNM1L Uniprot ID: O00429 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 10 Reactions: Gene Name: DOCK10 Uniprot ID: Q96BY6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 1 Reactions: Gene Name: DOCK1 Uniprot ID: Q14185 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 2 Reactions: Gene Name: DOCK2 Uniprot ID: Q92608 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 3 Reactions: Gene Name: DOCK3 Uniprot ID: Q8IZD9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 4 Reactions: Gene Name: DOCK4 Uniprot ID: Q8N1I0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 5 Reactions: Gene Name: DOCK5 Uniprot ID: Q9H7D0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 6 Reactions: Gene Name: DOCK6 Uniprot ID: Q96HP0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 7 Reactions: Gene Name: DOCK7 Uniprot ID: Q96N67 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dedicator of cytokinesis protein 8 Reactions: Gene Name: DOCK8 Uniprot ID: Q8NF50 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dynamin-1 Reactions: GTP + H2O = GDP + phosphate [RN:R00335] Gene Name: DNM1 Uniprot ID: Q05193 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Dynamin-2 Reactions: GTP + H2O = GDP + phosphate [RN:R00335] Gene Name: DNM2 Uniprot ID: P50570 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Elongation factor G, mitochondrial Reactions: Gene Name: GFM1 Uniprot ID: Q96RP9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ribosome-releasing factor 2, mitochondrial Reactions: Gene Name: GFM2 Uniprot ID: Q969S9 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Elongation factor Tu, mitochondrial Reactions: Gene Name: TUFM Uniprot ID: P49411 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Elongation factor Tu GTP-binding domain-containing protein 1 Reactions: Gene Name: EFTUD1 Uniprot ID: Q7Z2Z2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTPase-activating protein and VPS9 domain-containing protein 1 Reactions: Gene Name: GAPVD1 Uniprot ID: Q14C86 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Reactions: Gene Name: GNB1 Uniprot ID: P62873 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Reactions: Gene Name: GNB2 Uniprot ID: P62879 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Reactions: Gene Name: GNB3 Uniprot ID: P16520 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit beta-4 Reactions: Gene Name: GNB4 Uniprot ID: Q9HAV0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit beta-5 Reactions: Gene Name: GNB5 Uniprot ID: O14775 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Reactions: Gene Name: GNG10 Uniprot ID: P50151 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Reactions: Gene Name: GNG12 Uniprot ID: Q9UBI6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Reactions: Gene Name: GNG13 Uniprot ID: Q9P2W3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(T) subunit gamma-T1 Reactions: Gene Name: GNGT1 Uniprot ID: P63211 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Reactions: Gene Name: GNG3 Uniprot ID: P63215 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Reactions: Gene Name: GNG4 Uniprot ID: P50150 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Reactions: Gene Name: GNG5 Uniprot ID: P63218 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Reactions: Gene Name: GNG7 Uniprot ID: O60262 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Reactions: Gene Name: GNG8 Uniprot ID: Q9UK08 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Reactions: Gene Name: GNGT2 Uniprot ID: O14610 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein-like 1 Reactions: Gene Name: GNL1 Uniprot ID: P36915 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Probable E3 ubiquitin-protein ligase HERC1 Reactions: Gene Name: HERC1 Uniprot ID: Q15751 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Eukaryotic translation initiation factor 5 Reactions: Gene Name: EIF5 Uniprot ID: P55010 Protein Sequence: FASTA Gene Sequence: FASTA
Name: IQ motif and SEC7 domain-containing protein 1 Reactions: Gene Name: IQSEC1 Uniprot ID: Q6DN90 Protein Sequence: FASTA Gene Sequence: FASTA
Name: MAP kinase-activating death domain protein Reactions: Gene Name: MADD Uniprot ID: Q8WXG6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor DBS Reactions: Gene Name: MCF2L Uniprot ID: O15068 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related protein Rab-5A Reactions: Gene Name: RAB5A Uniprot ID: P20339 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related protein Rab-5B Reactions: Gene Name: RAB5B Uniprot ID: P61020 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ran-binding protein 3 Reactions: Gene Name: RANBP3 Uniprot ID: Q9H6Z4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ral guanine nucleotide dissociation stimulator-like 2 Reactions: Gene Name: RGL2 Uniprot ID: O15211 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ral guanine nucleotide dissociation stimulator-like 3 Reactions: Gene Name: RGL3 Uniprot ID: Q3MIN7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Synembryn-A Reactions: Gene Name: RIC8A Uniprot ID: Q9NPQ8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras and Rab interactor 1 Reactions: Gene Name: RIN1 Uniprot ID: Q13671 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras and Rab interactor 2 Reactions: Gene Name: RIN2 Uniprot ID: Q8WYP3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras and Rab interactor 3 Reactions: Gene Name: RIN3 Uniprot ID: Q8TB24 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTP-binding protein Rit1 Reactions: Gene Name: RIT1 Uniprot ID: Q92963 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTP-binding protein Rit2 Reactions: Gene Name: RIT2 Uniprot ID: Q99578 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor 5 Reactions: Gene Name: RAPGEF5 Uniprot ID: Q92565 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related GTP-binding protein A Reactions: Gene Name: RRAGA Uniprot ID: Q7L523 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related GTP-binding protein B Reactions: Gene Name: RRAGB Uniprot ID: Q5VZM2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related GTP-binding protein C Reactions: Gene Name: RRAGC Uniprot ID: Q9HB90 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-related GTP-binding protein D Reactions: Gene Name: RRAGD Uniprot ID: Q9NQL2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Secretion-regulating guanine nucleotide exchange factor Reactions: Gene Name: SERGEF Uniprot ID: Q9UGK8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: T-lymphoma invasion and metastasis-inducing protein 2 Reactions: Gene Name: TIAM2 Uniprot ID: Q8IVF5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein XRP2 Reactions: Gene Name: RP2 Uniprot ID: O75695 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Putative nucleoside diphosphate kinase Reactions: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331] Gene Name: NME2P1 Uniprot ID: O60361 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 Reactions: Gene Name: NUDT15 Uniprot ID: Q9NV35 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate-linked moiety X motif 17 Reactions: Gene Name: NUDT17 Uniprot ID: P0C025 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate-linked moiety X motif 18 Reactions: Gene Name: NUDT18 Uniprot ID: Q6ZVK8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate-linked moiety X motif 8, mitochondrial Reactions: Gene Name: NUDT8 Uniprot ID: Q8WV74 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GDP-fucose protein O-fucosyltransferase 1 Reactions: transfers an alpha-L-fucosyl residue from GDP-beta-L-fucose to the serine hydroxy group of a protein acceptor Gene Name: POFUT1 Uniprot ID: Q9H488 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho-related GTP-binding protein RhoU Reactions: Gene Name: RHOU Uniprot ID: Q7L0Q8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Alpha-(1,3)-fucosyltransferase Reactions: GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D- glucosaminyl-R [RN:R04553] Gene Name: FUT6 Uniprot ID: P51993 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GDP-fucose protein O-fucosyltransferase 2 Reactions: transfers an alpha-L-fucosyl residue from GDP-beta-L-fucose to the serine hydroxy group of a protein acceptor Gene Name: POFUT2 Uniprot ID: Q9Y2G5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(i) subunit alpha-1 Reactions: Gene Name: GNAI1 Uniprot ID: P63096 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Reactions: Gene Name: GNAS Uniprot ID: Q5JWF2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor VAV2 Reactions: Gene Name: VAV2 Uniprot ID: P52735 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho-guanine nucleotide exchange factor Reactions: Gene Name: RGNEF Uniprot ID: Q8N1W1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras guanyl-releasing protein 3 Reactions: Gene Name: RASGRP3 Uniprot ID: Q8IV61 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein RCC2 Reactions: Gene Name: RCC2 Uniprot ID: Q9P258 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein very KIND Reactions: Gene Name: KNDC1 Uniprot ID: Q76NI1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Nucleoside diphosphate kinase Reactions: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate [RN:R00331] Gene Name: NME4 Uniprot ID: A2IDD0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Abl interactor 1 Reactions: Gene Name: ABI1 Uniprot ID: Q8IZP0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTP-binding protein SAR1b Reactions: Gene Name: SAR1B Uniprot ID: Q9Y6B6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-GEF domain-containing family member 1A Reactions: Gene Name: RASGEF1A Uniprot ID: Q8N9B8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: G-protein-signaling modulator 1 Reactions: Gene Name: GPSM1 Uniprot ID: Q86YR5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GTP-binding protein GEM Reactions: Gene Name: GEM Uniprot ID: P55040 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rap guanine nucleotide exchange factor-like 1 Reactions: Gene Name: RAPGEFL1 Uniprot ID: Q9UHV5 Protein Sequence: FASTA
Name: Guanine nucleotide binding protein-like 1 Reactions: Gene Name: GNL1 Uniprot ID: B0V0L1 Protein Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 6 Reactions: Gene Name: ARHGEF6 Uniprot ID: Q15052 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-14 Reactions: Gene Name: GNA14 Uniprot ID: O95837 Protein Sequence: FASTA Gene Sequence: FASTA
Name: PH and SEC7 domain-containing protein 4 Reactions: Gene Name: PSD4 Uniprot ID: Q8NDX1 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 9 Reactions: Gene Name: ARHGEF9 Uniprot ID: O43307 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(k) subunit alpha Reactions: Gene Name: GNAI3 Uniprot ID: P08754 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Epithelial cell-transforming sequence 2 oncogene-like Reactions: Gene Name: ECT2L Uniprot ID: Q008S8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Pleckstrin homology domain-containing family G member 6 Reactions: Gene Name: PLEKHG6 Uniprot ID: Q3KR16 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(i) subunit alpha-2 Reactions: Gene Name: GNAI2 Uniprot ID: P04899 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(t) subunit alpha-2 Reactions: Gene Name: GNAT2 Uniprot ID: P19087 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 37 Reactions: Gene Name: ARHGEF37 Uniprot ID: A1IGU5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: PH and SEC7 domain-containing protein 3 Reactions: Gene Name: PSD3 Uniprot ID: Q9NYI0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: PH and SEC7 domain-containing protein 1 Reactions: Gene Name: PSD Uniprot ID: A5PKW4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(o) subunit alpha Reactions: Gene Name: GNAO1 Uniprot ID: P09471 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-GEF domain-containing family member 1B Reactions: Gene Name: RASGEF1B Uniprot ID: Q0VAM2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 18 Reactions: Gene Name: ARHGEF18 Uniprot ID: Q6ZSZ5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: ALS2 C-terminal-like protein Reactions: Gene Name: ALS2CL Uniprot ID: Q60I27 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Switch-associated protein 70 Reactions: Gene Name: SWAP70 Uniprot ID: Q9UH65 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-specific guanine nucleotide-releasing factor RalGPS2 Reactions: Gene Name: RALGPS2 Uniprot ID: Q86X27 Protein Sequence: FASTA Gene Sequence: FASTA
Name: FERM, RhoGEF and pleckstrin domain-containing protein 2 Reactions: Gene Name: FARP2 Uniprot ID: O94887 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ral guanine nucleotide dissociation stimulator-like 1 Reactions: Gene Name: RGL1 Uniprot ID: Q9NZL6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-13 Reactions: Gene Name: GNA13 Uniprot ID: Q14344 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Vav-like protein C9orf100 Reactions: Gene Name: C9orf100 Uniprot ID: Q8N4T4 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Probable guanine nucleotide exchange factor MCF2L2 Reactions: Gene Name: MCF2L2 Uniprot ID: Q86YR7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 7 Reactions: Gene Name: ARHGEF7 Uniprot ID: Q14155 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein (G protein), alpha 14 Reactions: Gene Name: GNA14 Uniprot ID: B1ALW3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein-like 1 Reactions: Gene Name: GNL1 Uniprot ID: A2AB27 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-12 Reactions: Gene Name: GNA12 Uniprot ID: Q03113 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-specific guanine nucleotide-releasing factor RalGPS1 Reactions: Gene Name: RALGPS1 Uniprot ID: Q5JS13 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 11 Reactions: Gene Name: ARHGEF11 Uniprot ID: O15085 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Growth factor receptor-bound protein 2 Reactions: Gene Name: GRB2 Uniprot ID: P62993 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein (G protein), beta polypeptide 1 Reactions: Gene Name: GNB1 Uniprot ID: B1AKQ8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 10-like protein Reactions: Gene Name: ARHGEF10L Uniprot ID: Q9HCE6 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein (G protein), q polypeptide Reactions: Gene Name: GNAQ Uniprot ID: B1AM21 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Protein SOLO Reactions: Gene Name: SOLO Uniprot ID: Q8TER5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Prolactin regulatory element-binding protein Reactions: Gene Name: PREB Uniprot ID: Q9HCU5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 4 Reactions: Gene Name: ARHGEF4 Uniprot ID: Q9NR80 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor for Rab-3A Reactions: Gene Name: RAB3IL1 Uniprot ID: Q8TBN0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Engulfment and cell motility protein 1 Reactions: Gene Name: ELMO1 Uniprot ID: Q92556 Protein Sequence: FASTA Gene Sequence: FASTA
Name: GRB2-related adapter protein Reactions: Gene Name: GRAP Uniprot ID: Q13588 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(z) subunit alpha Reactions: Gene Name: GNAZ Uniprot ID: P19086 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Engulfment and cell motility protein 3 Reactions: Gene Name: ELMO3 Uniprot ID: Q96BJ8 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide exchange factor GEFT Reactions: Gene Name: GEFT Uniprot ID: Q86VW2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Differentially expressed in FDCP 6 homolog Reactions: Gene Name: DEF6 Uniprot ID: Q9H4E7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Alpha-catulin Reactions: Gene Name: CTNNAL1 Uniprot ID: Q9UBT7 Protein Sequence: FASTA Gene Sequence: FASTA
Name: IQ motif and SEC7 domain-containing protein 3 Reactions: Gene Name: IQSEC3 Uniprot ID: Q9UPP2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Engulfment and cell motility protein 2 Reactions: Gene Name: ELMO2 Uniprot ID: Q96JJ3 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 17 Reactions: Gene Name: ARHGEF17 Uniprot ID: Q96PE2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ras-GEF domain-containing family member 1C Reactions: Gene Name: RASGEF1C Uniprot ID: Q8N431 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 12 Reactions: Gene Name: ARHGEF12 Uniprot ID: Q9NZN5 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Ephexin-1 Reactions: Gene Name: NGEF Uniprot ID: Q8N5V2 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide binding protein-like 1 Reactions: Gene Name: GNL1 Uniprot ID: B0V0L0 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein G(olf) subunit alpha Reactions: Gene Name: GNAL Uniprot ID: P38405 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Guanine nucleotide-binding protein subunit alpha-15 Reactions: Gene Name: GNA15 Uniprot ID: P30679 Protein Sequence: FASTA Gene Sequence: FASTA
Name: Rho guanine nucleotide exchange factor 3 Reactions: Gene Name: ARHGEF3 Uniprot ID: Q9NR81 Protein Sequence: FASTA Gene Sequence: FASTA

This project is supported by Genome Alberta & Genome Canada, a not-for-profit organization that is leading Canada's national genomics strategy with $600 million in funding from the federal government.