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Record Information
Version3.6
Creation Date2006-08-13 02:26:15 UTC
Update Date2016-02-11 01:06:24 UTC
HMDB IDHMDB03642
Secondary Accession NumbersNone
Metabolite Identification
Common NameStrontium
DescriptionStrontium presents a health problem since it substitutes for calcium in bone, preventing expulsion from the body. Physiologically, it exists as an ion in the body.
Structure
Thumb
Synonyms
ValueSource
SR(2+)ChEBI
SR2+ChEBI
StrontiumChEBI
STRONTIUM ionChEBI
Chemical FormulaSr
Average Molecular Weight87.62
Monoisotopic Molecular Weight87.905614339
IUPAC Namestrontium(2+) ion
Traditional Namestrontium(2+) ion
CAS Registry Number7440-24-6
SMILES
[Sr++]
InChI Identifier
InChI=1S/Sr/q+2
InChI KeyInChIKey=PWYYWQHXAPXYMF-UHFFFAOYSA-N
Chemical Taxonomy
DescriptionThis compound belongs to the class of inorganic compounds known as homogeneous alkaline earth metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a alkaline earth metal atom.
KingdomInorganic compounds
Super ClassHomogeneous metal compounds
ClassHomogeneous alkaline earth metal compounds
Sub ClassNot Available
Direct ParentHomogeneous alkaline earth metal compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous alkaline earth metal
  • Acyclic compound
Molecular FrameworkAcyclic compounds
External Descriptors
Ontology
StatusDetected and Quantified
OriginNot Available
Biofunction
  • Essential minerals
  • Semi-essential minerals
ApplicationNot Available
Cellular locationsNot Available
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting Point777 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP-0.3ChemAxon
Physiological Charge2ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
SpectraNot Available
Biological Properties
Cellular LocationsNot Available
Biofluid Locations
  • Blood
  • Cerebrospinal Fluid (CSF)
  • Saliva
  • Urine
Tissue LocationNot Available
PathwaysNot Available
Normal Concentrations
BiofluidStatusValueAgeSexConditionReferenceDetails
BloodDetected and Quantified0.32 +/- 0.14 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.44 +/- 0.17 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.32 +/- 0.14 uMAdult (>18 years old)BothNormal details
BloodDetected and Quantified0.37 +/- 0.10 uMAdult (>18 years old)BothNormal
    • Geigy Scientific ...
details
BloodDetected and Quantified0.44 +/- 0.17 uMElderly (>65 years old)BothNormal details
Cerebrospinal Fluid (CSF)Detected and Quantified1.120 +/- 2.481 uMAdult (>18 years old)Not SpecifiedNormal details
SalivaDetected and Quantified0.534 +/- 0.46 uMAdult (>18 years old)BothNormal
    • Zerihun T. Dame, ...
details
SalivaDetected and Quantified0.0247 +/- 0.0110 uMAdult (>18 years old)Male
Normal
details
SalivaDetected and Quantified0.0211 +/- 0.0131 uMAdult (>18 years old)Male
Normal
details
SalivaDetected and Quantified0.0395 +/- 0.0397 uMAdult (>18 years old)Male
Normal
details
SalivaDetected and Quantified0.103-0.297 uMChildren (1-13 years old)BothNormal
    • Gian Paolo Sighin...
details
SalivaDetected and Quantified0.399 (0.228-33.440) uMAdolescent (13-18 years old)MaleNormal details
SalivaDetected and Quantified15.407 +/- 16.549 uMAdult (>18 years old)Male
Normal
details
SalivaDetected and Quantified13.125 +/- 23.739 uMAdult (>18 years old)Male
Normal
details
SalivaDetected and Quantified0.0112 +/- 0.0033 uMAdult (>18 years old)Not Specified
Normal
details
SalivaDetected and Quantified0.00902 +/- 0.00308 uMAdult (>18 years old)Not Specified
Normal
details
SalivaDetected and Quantified0.0233 +/- 0.0175 uMAdult (>18 years old)Male
Normal
details
UrineDetected and Quantified0.163 (0.030-0.415) umol/mmol creatinineAdult (>18 years old)Both
Normal
details
UrineDetected and Quantified0.1333 umol/mmol creatinineNot SpecifiedNot SpecifiedNormal
    • Geigy scientific ...
details
Abnormal Concentrations
BiofluidStatusValueAgeSexConditionReferenceDetails
BloodDetected and Quantified0.42 +/- 0.13 uMAdult (>18 years old)Both
Parkinson's disease
details
BloodDetected and Quantified0.27 +/- 0.09 uMAdult (>18 years old)Both
Multiple sclerosis
details
BloodDetected and Quantified0.32 +/- 0.10 uMAdult (>18 years old)Both
Parkinson's disease
details
BloodDetected and Quantified0.44 +/- 0.16 uMElderly (>65 years old)Both
Alzheimer's disease
details
Associated Disorders and Diseases
Disease References
Alzheimer's disease
  1. Bocca B, Forte G, Petrucci F, Pino A, Marchione F, Bomboi G, Senofonte O, Giubilei F, Alimonti A: Monitoring of chemical elements and oxidative damage in patients affected by Alzheimer's disease. Ann Ist Super Sanita. 2005;41(2):197-203. [16244393 ]
Multiple sclerosis
  1. Forte G, Visconti A, Santucci S, Ghazaryan A, Figa-Talamanca L, Cannoni S, Bocca B, Pino A, Violante N, Alimonti A, Salvetti M, Ristori G: Quantification of chemical elements in blood of patients affected by multiple sclerosis. Ann Ist Super Sanita. 2005;41(2):213-6. [16244395 ]
Parkinson's disease
  1. Forte G, Alimonti A, Pino A, Stanzione P, Brescianini S, Brusa L, Sancesario G, Violante N, Bocca B: Metals and oxidative stress in patients with Parkinson's disease. Ann Ist Super Sanita. 2005;41(2):189-95. [16244392 ]
Associated OMIM IDs
DrugBank IDNot Available
DrugBank Metabolite IDNot Available
Phenol Explorer Compound IDNot Available
Phenol Explorer Metabolite IDNot Available
FoodDB IDFDB003786
KNApSAcK IDNot Available
Chemspider ID94599
KEGG Compound IDC13884
BioCyc IDCPD-8886
BiGG IDNot Available
Wikipedia LinkStrontium
NuGOwiki LinkHMDB03642
Metagene LinkHMDB03642
METLIN IDNot Available
PubChem Compound104798
PDB IDSR
ChEBI ID35104
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General References
  1. Schaafsma A, de Vries PJ, Saris WH: Delay of natural bone loss by higher intakes of specific minerals and vitamins. Crit Rev Food Sci Nutr. 2001 May;41(4):225-49. [11401244 ]
  2. D'Haese PC, De Broe ME: Adequacy of dialysis: trace elements in dialysis fluids. Nephrol Dial Transplant. 1996;11 Suppl 2:92-7. [8804004 ]